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Volumn 24, Issue 12, 2015, Pages 2585-2599

Human umbilical cord mesenchymal stem cells promote breast cancer metastasis by interleukin-8-and interleukin-6-dependent induction of CD44+/CD24− cells

Author keywords

Epithelial to mesenchymal transition (EMT); Interleukin 6 (IL 6); Interleukin 8 (IL 8); Mesenchymal stem cells (MSCs)

Indexed keywords

CD24 ANTIGEN; HERMES ANTIGEN; INTERLEUKIN 6; INTERLEUKIN 8; CD24 PROTEIN, HUMAN; CD44 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

EID: 84949796234     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368915X687462     Document Type: Article
Times cited : (49)

References (45)
  • 2
    • 8444230395 scopus 로고    scopus 로고
    • Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clin
    • Benoy, I. H.; Salgado, R.; Van Dam, P.; Geboers, K.; Van Marck, E.; Scharpé, S.; Vermeulen, P. B.; Dirix, L. Y. Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clin. Cancer Res. 10:7157-7162; 2004
    • (2004) Cancer Res , vol.10 , pp. 7157-7162
    • Benoy, I.H.1    Salgado, R.2    Van Dam, P.3    Geboers, K.4    Van Marck, E.5    Scharpé, S.6    Vermeulen, P.B.7    Dirix, L.Y.8
  • 3
    • 25444495269 scopus 로고    scopus 로고
    • Opinion: Migrating cancer stem cells-An integrated concept of malignant tumour progression. Nat
    • Brabletz, T.; Jung, A.; Spaderna, S.; Hlubek, F.; Kirchner, T. Opinion: Migrating cancer stem cells-An integrated concept of malignant tumour progression. Nat. Rev. Cancer 5:744-749; 2005
    • (2005) Rev. Cancer , vol.5 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 5
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger, J. A.; Kipps, T. J. CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment. Blood 107:1761-1767; 2006
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.A.1    Kipps, T.J.2
  • 10
    • 84866481797 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived interleukin-6 and vascular endothelial growth factor promote breast cancer cell migration
    • De Luca, A.; Lamura, L.; Gallo, M.; Maffia, V.; Normanno, N. Mesenchymal stem cell-derived interleukin-6 and vascular endothelial growth factor promote breast cancer cell migration. J. Cell. Biochem. 113:3363-3370; 2012
    • (2012) J. Cell. Biochem , vol.113 , pp. 3363-3370
    • De Luca, A.1    Lamura, L.2    Gallo, M.3    Maffia, V.4    Normanno, N.5
  • 12
    • 79960952144 scopus 로고    scopus 로고
    • IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells
    • Fernando, R. I.; Castillo, M. D.; Litzinger, M.; Hamilton, D. H.; Palena, C. IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells. Cancer Res. 71:5296-5306; 2011
    • (2011) Cancer Res , vol.71 , pp. 5296-5306
    • Fernando, R.I.1    Castillo, M.D.2    Litzinger, M.3    Hamilton, D.H.4    Palena, C.5
  • 13
    • 42549114180 scopus 로고    scopus 로고
    • Mesenchymal stem cells: An emerging tool for cancer targeting and therapy
    • Fritz, V.; Jorgensen, C. Mesenchymal stem cells: An emerging tool for cancer targeting and therapy. Curr. Stem Cell Res. Ther. 3:32-42; 2008
    • (2008) Curr. Stem Cell Res. Ther , vol.3 , pp. 32-42
    • Fritz, V.1    Jorgensen, C.2
  • 15
    • 34547619243 scopus 로고    scopus 로고
    • Mesenchymal stem cells in cancer: Tumor-associated fibroblasts and cell-based delivery vehicles
    • Hall, B.; Dembinski, J.; Sasser, A. K.; Studeny, M., Andreeff, M.; Marini, F. Mesenchymal stem cells in cancer: Tumor-associated fibroblasts and cell-based delivery vehicles. Int. J. Hematol. 86:8-16; 2007
    • (2007) Int. J. Hematol , vol.86 , pp. 8-16
    • Hall, B.1    Dembinski, J.2    Sasser, A.K.3    Studeny, M.4    Reeff, M.5    Marini, F.6
  • 18
    • 68049122875 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Immunobiology and role in immunomodulation and tissue regeneration
    • Kode, J. A.; Mukherjee, S.; Joglekar, M. V.; Hardikar, A. A. Mesenchymal stem cells: Immunobiology and role in immunomodulation and tissue regeneration. Cytotherapy 11:377-391; 2009
    • (2009) Cytotherapy , vol.11 , pp. 377-391
    • Kode, J.A.1    Mukherjee, S.2    Joglekar, M.V.3    Hardikar, A.A.4
  • 19
    • 80053401068 scopus 로고    scopus 로고
    • Breast cancer stem cells; cytokine networks; and the tumor microenvironment
    • Korkaya, H.; Liu, S.; Wicha, M. S. Breast cancer stem cells; cytokine networks; and the tumor microenvironment. J. Clin. Invest. 121:3804-3809; 2011
    • (2011) J. Clin. Invest , vol.121 , pp. 3804-3809
    • Korkaya, H.1    Liu, S.2    Wicha, M.S.3
  • 21
    • 84866307571 scopus 로고    scopus 로고
    • Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling
    • Li, H.-J.; Reinhardt, F.; Herschman, H. R.; Weinberg, R. A. Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer Discov. 2:840-855; 2012
    • (2012) Cancer Discov , vol.2 , pp. 840-855
    • Li, H.-J.1    Reinhardt, F.2    Herschman, H.R.3    Weinberg, R.A.4
  • 24
    • 66249083525 scopus 로고    scopus 로고
    • Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer
    • Loebinger, M. R.; Eddaoudi, A.; Davies, D.; Janes, S. M. Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer. Cancer Res. 69:4134-4142; 2009
    • (2009) Cancer Res , vol.69 , pp. 4134-4142
    • Loebinger, M.R.1    Eddaoudi, A.2    Davies, D.3    Janes, S.M.4
  • 25
    • 33746936122 scopus 로고    scopus 로고
    • Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials
    • Lu, L. L.; Liu, Y. J.; Yang, S. G.; Zhao, Q. J.; Wang, X.; Gong, W.; Han, Z. B.; Xu, Z. S.; Lu, Y. X.; Liu, D.; Chen, Z. Z.; Han, Z. C. Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. Haematologica 91: 1017-1026; 2006
    • (2006) Haematologica , vol.91 , pp. 1017-1026
    • Lu, L.L.1    Liu, Y.J.2    Yang, S.G.3    Zhao, Q.J.4    Wang, X.5    Gong, W.6    Han, Z.B.7    Xu, Z.S.8    Lu, Y.X.9    Liu, D.10    Chen, Z.Z.11    Han, Z.C.12
  • 30
    • 77950553914 scopus 로고    scopus 로고
    • No contribution of umbilical cord mesenchymal stromal cells to capillarization and venularization of hepatic sinusoids accompanied by hepatic differentiation in carbon tetrachloride-induced mouse liver fibrosis
    • Ren, H.; Zhao, Q.; Cheng, T.; Lu, S.; Chen, Z.; Meng, L.; Zhu, X; Yang, S.; Xing, W.; Xiao, Y.; Ren, Q.; Chi, Y.; Gu, D.; Yang, R.; Han, Z. C. No contribution of umbilical cord mesenchymal stromal cells to capillarization and venularization of hepatic sinusoids accompanied by hepatic differentiation in carbon tetrachloride-induced mouse liver fibrosis. Cytotherapy 12:371-383; 2010
    • (2010) Cytotherapy , vol.12 , pp. 371-383
    • Ren, H.1    Zhao, Q.2    Cheng, T.3    Lu, S.4    Chen, Z.5    Meng, L.6    Zhu, X.7    Yang, S.8    Xing, W.9    Xiao, Y.10    Ren, Q.11    Chi, Y.12    Gu, D.13    Yang, R.14    Han, Z.C.15
  • 31
    • 78349245224 scopus 로고    scopus 로고
    • Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk
    • Rhodes, L. V.; Antoon, J. W.; Muir, S. E.; Elliott, S.; Beckman, B. S.; Burow, M. E. Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk. Mol. Cancer 9: 295; 2010
    • (2010) Mol. Cancer , vol.9
    • Rhodes, L.V.1    Antoon, J.W.2    Muir, S.E.3    Elliott, S.4    Beckman, B.S.5    Burow, M.E.6
  • 34
    • 10744223635 scopus 로고    scopus 로고
    • Interleukin 1 system and sexsteroid receptor expression in human breast cancer: Interleukin 1alpha protein secretion is correlated with malignant phenotype
    • Singer, C. F.; Kronsteiner, N.; Hudelist, G.; Marton, E.; Walter, I.; Kubista, M.; Czerwenka, K.; Schreiber, M.; Seifert, M.; Kubista, E. Interleukin 1 system and sex steroid receptor expression in human breast cancer: Interleukin 1alpha protein secretion is correlated with malignant phenotype. Clin. Cancer Res. 9: 4877-4883; 2003
    • (2003) Clin. Cancer Res , vol.9 , pp. 4877-4883
    • Singer, C.F.1    Kronsteiner, N.2    Hudelist, G.3    Marton, E.4    Walter, I.5    Kubista, M.6    Czerwenka, K.7    Schreiber, M.8    Seifert, M.9    Kubista, E.10
  • 35
    • 84873333749 scopus 로고    scopus 로고
    • Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms
    • Singh, J. K.; Farnie, G.; Bundred, N. J.; Simões, B. M.; Shergill, A.; Landberg, G.; Howell, S. J.; Clarke, R. B. Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms. Clin. Cancer Res. 19: 643-656; 2013
    • (2013) Clin. Cancer Res , vol.19 , pp. 643-656
    • Singh, J.K.1    Farnie, G.2    Bundred, N.J.3    Simões, B.M.4    Shergill, A.5    Landberg, G.6    Howell, S.J.7    Clarke, R.B.8
  • 38
    • 79959461779 scopus 로고    scopus 로고
    • Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+CD25+ Forkhead Boxp3 (FOXP3)+ regulatory T cells and balancing anti-and pro-inflammatory factors
    • Sun, J.; Han, Z. B.; Liao, W.; Yang, S. G.; Yang, Z.; Yu, J.; Meng, L.; Wu, R.; Han, Z. C. Intrapulmonary delivery of human umbilical cord mesenchymal stem cells attenuates acute lung injury by expanding CD4+CD25+ Forkhead Boxp3 (FOXP3)+ regulatory T cells and balancing anti-and pro-inflammatory factors. Cell. Physiol. Biochem. 27:587-596; 2011
    • (2011) Cell. Physiol. Biochem. , vol.27 , pp. 587-596
    • Sun, J.1    Han, Z.B.2    Liao, W.3    Yang, S.G.4    Yang, Z.5    Yu, J.6    Meng, L.7    Wu, R.8    Han, Z.C.9
  • 39
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery, J. P.; Sleeman, J. P. Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol. 7:131-142; 2006
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 40
    • 78651251372 scopus 로고    scopus 로고
    • P38 MAPKcontributes to the growth inhibition of leukemic tumor cells mediated by human umbilical cord mesenchymal stem cells
    • Tian, K.; Yang, S.; Ren, Q.; Han, Z.; Lu, S.; Ma, F.; Zhang, L.; Han, Z. p38 MAPK contributes to the growth inhibition of leukemic tumor cells mediated by human umbilical cord mesenchymal stem cells. Cell. Physiol. Biochem. 26: 799-808; 2010
    • (2010) Cell. Physiol. Biochem , vol.26 , pp. 799-808
    • Tian, K.1    Yang, S.2    Ren, Q.3    Han, Z.4    Lu, S.5    Ma, F.6    Zhang, L.7    Han, Z.8
  • 41
    • 68049147001 scopus 로고    scopus 로고
    • Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging
    • Wang, H.; Cao, F.; De, A.; Cao, Y.; Contag, C.; Gambhir, S. S.; Wu, J. C.; Chen, X. Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells 27:1548-1558; 2009
    • (2009) Stem Cells , vol.27 , pp. 1548-1558
    • Wang, H.1    Cao, F.2    De, A.3    Cao, Y.4    Contag, C.5    Gambhir, S.S.6    Wu, J.C.7    Chen, X.8
  • 43
    • 84864979988 scopus 로고    scopus 로고
    • Mesenchymal stem cells play a potential role in regulating the establishment and maintenance of epithelial-mesenchymal transition in MCF7 human breast cancer cells by paracrine and induced autocrine TGF-b
    • Xu, Q.; Wang, L.; Li, H.; Han, Q.; Li, J.; Qu, X.; Huang, S.; Zhao, R. C. Mesenchymal stem cells play a potential role in regulating the establishment and maintenance of epithelial-mesenchymal transition in MCF7 human breast cancer cells by paracrine and induced autocrine TGF-b. Int. J. Oncol. 41:959-968; 2012
    • (2012) Int. J. Oncol , vol.41 , pp. 959-968
    • Xu, Q.1    Wang, L.2    Li, H.3    Han, Q.4    Li, J.5    Qu, X.6    Huang, S.7    Zhao, R.C.8
  • 44
    • 84872167781 scopus 로고    scopus 로고
    • Human umbilical cord mesenchymal stem cells as vehicles of CD20-specific TRAIL fusion protein delivery: A double-target therapy against non-Hodgkin’s lymphoma
    • Yan, C.; Li, S.; Li, Z.; Peng, H.; Yuan, X.; Jiang, L.; Zhang, Y.; Fan, D.; Hu, X.; Yang, M.; Xiong, D. Human umbilical cord mesenchymal stem cells as vehicles of CD20-specific TRAIL fusion protein delivery: A double-target therapy against non-Hodgkin’s lymphoma. Mol. Pharm. 10:142-151; 2013
    • (2013) Mol. Pharm , vol.10 , pp. 142-151
    • Yan, C.1    Li, S.2    Li, Z.3    Peng, H.4    Yuan, X.5    Jiang, L.6    Zhang, Y.7    Fan, D.8    Hu, X.9    Yang, M.10    Xiong, D.11
  • 45
    • 77955290246 scopus 로고    scopus 로고
    • Intravenous administration of bone marrow mesenchymal stem cells benefits experimental autoimmune myasthenia gravis mice through an immunomodulatory action. Scand
    • Yu, J.; Zheng, C.; Ren, X.; Li, J.; Liu, M.; Zhang, L.; Liang, L.; Du, W.; Han, Z. C. Intravenous administration of bone marrow mesenchymal stem cells benefits experimental autoimmune myasthenia gravis mice through an immunomodulatory action. Scand. J. Immunol. 72:242-249; 2010.
    • (2010) J. Immunol , vol.72 , pp. 242-249
    • Yu, J.1    Zheng, C.2    Ren, X.3    Li, J.4    Liu, M.5    Zhang, L.6    Liang, L.7    Du, W.8    Han, Z.C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.