Mechanistic Insights into R776H Mediated Activation of Epidermal Growth Factor Receptor Kinase

Biochemistry

Volumn 54, Issue 27, 2015, Pages 4216-4225

  Ruan, Zheng ^a,b   Kannan, Natarajan ^a  

^a University of Georgia   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DIMERS; ENZYMES; MOLECULAR DYNAMICS; NUMBERING SYSTEMS; PHOSPHORYLATION;

ASYMMETRIC DIMERS; CO-TRANSFECTIONS; EPIDERMAL GROWTH FACTOR RECEPTORS; KINASE ACTIVATION; MOLECULAR DYNAMICS SIMULATIONS; MUTATIONAL ACTIVATION; RECURRENT MUTATION; REGULATORY INTERACTIONS;

CHEMICAL ACTIVATION;

DIMER; EPIDERMAL GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; SIMULATION; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; POINT MUTATION; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ANIMALS; CHO CELLS; CRICETULUS; HUMANS; MOLECULAR DYNAMICS SIMULATION; PHOSPHORYLATION; POINT MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84949672840     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00444     Document Type: Article

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