-
1
-
-
66749102156
-
The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour
-
Kompier, L. C. et al. The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour. J. Pathol. 218, 104-112 (2009).
-
(2009)
J. Pathol.
, vol.218
, pp. 104-112
-
-
Kompier, L.C.1
-
2
-
-
84883813935
-
EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: Update 2013
-
Babjuk, M. et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013. Eur. Urol. 64, 639-653 (2013).
-
(2013)
Eur. Urol.
, vol.64
, pp. 639-653
-
-
Babjuk, M.1
-
3
-
-
0027285323
-
Predictability of recurrent and progressive disease in individual patients with primary superficial bladder cancer
-
Kiemeney, L. A., Witjes, J. A., Heijbroek, R. P., Verbeek, A. L. & Debruyne, F. M. Predictability of recurrent and progressive disease in individual patients with primary superficial bladder cancer. J. Urol. 150, 60-64 (1993).
-
(1993)
J. Urol.
, vol.150
, pp. 60-64
-
-
Kiemeney, L.A.1
Witjes, J.A.2
Heijbroek, R.P.3
Verbeek, A.L.4
Debruyne, F.M.5
-
4
-
-
32944465832
-
Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: A combined analysis of 2596 patients from seven EORTC trials
-
Sylvester, R. J. et al. Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. Eur. Urol. 49, 466-477 (2006).
-
(2006)
Eur. Urol.
, vol.49
, pp. 466-477
-
-
Sylvester, R.J.1
-
5
-
-
84949632227
-
-
Surveillance Epidemiology and End Results Program (SEER). seer.cancer.gov [online]
-
Surveillance, Epidemiology, and End Results Program (SEER). seer.cancer.gov [online], http://seer.cancer.gov/statfacts/html/urinb.html (2015).
-
(2015)
-
-
-
6
-
-
84904042826
-
Conditional survival after radical cystectomy for bladder cancer: Evidence for a patient changing risk profile over time
-
Ploussard, G. et al. Conditional survival after radical cystectomy for bladder cancer: evidence for a patient changing risk profile over time. Eur. Urol. 66, 361-370 (2014).
-
(2014)
Eur. Urol.
, vol.66
, pp. 361-370
-
-
Ploussard, G.1
-
7
-
-
79957960529
-
International phase III trial assessing neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: Long-term results of the BA06 30894 trial
-
International Collaboration of Trialists et al. International phase III trial assessing neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: long-term results of the BA06 30894 trial. J. Clin. Oncol. 29, 2171-2177 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 2171-2177
-
-
-
8
-
-
84979849583
-
Blaascarcinoom: Kankerzorg in beeld
-
Visser, O. & Horenblas, S. Blaascarcinoom: Kankerzorg in beeld. Intergraal kankercentrum Nederland [online], https://www.iknl.nl/docs/default-source/KIB-rapportages/portfolio-kib- blaascarcinoom.pdf?sfvrsn=2 (2014).
-
(2014)
Intergraal Kankercentrum Nederland [Online]
-
-
Visser, O.1
Horenblas, S.2
-
9
-
-
84876305104
-
Incidence, survival and mortality rates of stage-specific bladder cancer in United States: A trend analysis
-
Abdollah, F. et al. Incidence, survival and mortality rates of stage-specific bladder cancer in United States: a trend analysis. Cancer Epidemiol. 37, 219-225 (2013).
-
(2013)
Cancer Epidemiol.
, vol.37
, pp. 219-225
-
-
Abdollah, F.1
-
11
-
-
55349136976
-
A history of cancer chemotherapy
-
DeVita, V. T. Jr, & Chu, E. A history of cancer chemotherapy. Cancer Res. 68, 8643-8653 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 8643-8653
-
-
DeVita, V.T.1
Chu, E.2
-
12
-
-
84899485656
-
Targeted therapies in urothelial carcinoma
-
Ghosh, M., Brancato, S. J., Agarwal, P. K. & Apolo, A. B. Targeted therapies in urothelial carcinoma. Curr. Opin. Oncol. 26, 305-320 (2014).
-
(2014)
Curr. Opin. Oncol.
, vol.26
, pp. 305-320
-
-
Ghosh, M.1
Brancato, S.J.2
Agarwal, P.K.3
Apolo, A.B.4
-
13
-
-
84923097970
-
Intratumour heterogeneity in urologic cancers: From molecular evidence to clinical implications
-
Gerlinger, M. et al. Intratumour heterogeneity in urologic cancers: from molecular evidence to clinical implications. Eur. Urol. 67, 729-737 (2015).
-
(2015)
Eur. Urol.
, vol.67
, pp. 729-737
-
-
Gerlinger, M.1
-
14
-
-
84863000299
-
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
-
Diaz, L. A. Jr. et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 486, 537-540 (2012).
-
(2012)
Nature
, vol.486
, pp. 537-540
-
-
Diaz, L.A.1
-
15
-
-
36849022660
-
A phase II trial of cisplatin, fixed dose-rate gemcitabine and gefitinib for advanced urothelial tract carcinoma: Results of the Cancer and Leukaemia Group B 90102
-
Philips, G. K. et al. A phase II trial of cisplatin, fixed dose-rate gemcitabine and gefitinib for advanced urothelial tract carcinoma: results of the Cancer and Leukaemia Group B 90102. BJU Int. 101, 20-25 (2007).
-
(2007)
BJU Int.
, vol.101
, pp. 20-25
-
-
Philips, G.K.1
-
16
-
-
84864423349
-
A systematic review of neoadjuvant and adjuvant chemotherapy for muscle-invasive bladder cancer
-
Meeks, J. J. et al. A systematic review of neoadjuvant and adjuvant chemotherapy for muscle-invasive bladder cancer. Eur. Urol. 62, 523-533 (2012).
-
(2012)
Eur. Urol.
, vol.62
, pp. 523-533
-
-
Meeks, J.J.1
-
17
-
-
33645734205
-
Contributions of human xenografts to anticancer drug development
-
Sausville, E. A. & Burger, A. M. Contributions of human xenografts to anticancer drug development. Cancer Res. 66, 3351-3354 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 3351-3354
-
-
Sausville, E.A.1
Burger, A.M.2
-
18
-
-
84940776859
-
Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies
-
Jäger, W. et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget 6, 21522-21532 (2015).
-
(2015)
Oncotarget
, vol.6
, pp. 21522-21532
-
-
Jäger, W.1
-
19
-
-
84883808098
-
Hiding in plain view: Genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa
-
Jäger, W. et al. Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa. J. Urol. 190, 1404-1409 (2013).
-
(2013)
J. Urol.
, vol.190
, pp. 1404-1409
-
-
Jäger, W.1
-
20
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
Schlessinger, J. Cell signaling by receptor tyrosine kinases. Cell 103, 211-225 (2000).
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
21
-
-
84897022815
-
Comprehensive molecular characterization of urothelial bladder carcinoma
-
Cancer Genome Atlas Research Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 507, 315-322 (2014).
-
(2014)
Nature
, vol.507
, pp. 315-322
-
-
Cancer Genome Atlas Research Network1
-
22
-
-
84920655875
-
Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladder
-
Kim, P. H. et al. Genomic predictors of survival in patients with high-grade urothelial carcinoma of the bladder. Eur. Urol. 67, 198-201 (2015).
-
(2015)
Eur. Urol.
, vol.67
, pp. 198-201
-
-
Kim, P.H.1
-
23
-
-
34548435148
-
Targeted therapies in bladder cancer-an update
-
Black, P. C., Agarwal, P. K. & Dinney, C. P. Targeted therapies in bladder cancer-an update. Urol. Oncol. 25, 433-438 (2007).
-
(2007)
Urol. Oncol.
, vol.25
, pp. 433-438
-
-
Black, P.C.1
Agarwal, P.K.2
Dinney, C.P.3
-
24
-
-
36749029619
-
Distinctive expression pattern of ErbB family receptors signifies an aggressive variant of bladder cancer
-
Kassouf, W. et al. Distinctive expression pattern of ErbB family receptors signifies an aggressive variant of bladder cancer. J. Urol. 179, 353-358 (2008).
-
(2008)
J. Urol.
, vol.179
, pp. 353-358
-
-
Kassouf, W.1
-
25
-
-
38849152398
-
Targeted therapies: A new generation of cancer treatments
-
Gerber, D. E. Targeted therapies: a new generation of cancer treatments. Am. Fam. Physician 77, 311-319 (2008).
-
(2008)
Am. Fam. Physician
, vol.77
, pp. 311-319
-
-
Gerber, D.E.1
-
26
-
-
22044442973
-
Tyrosine kinases as targets for cancer therapy
-
Krause, D. S. & Van Etten, R. A. Tyrosine kinases as targets for cancer therapy. N. Engl. J. Med. 353, 172-187 (2005).
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 172-187
-
-
Krause, D.S.1
Van Etten, R.A.2
-
27
-
-
70749137263
-
Targeting EGFR with photodynamic therapy in combination with erbitux enhances in vivo bladder tumor response
-
Bhuvaneswari, R., Gan, Y. Y., Soo, K. C. & Olivo, M. Targeting EGFR with photodynamic therapy in combination with erbitux enhances in vivo bladder tumor response. Mol. Cancer 8, 94 (2009).
-
(2009)
Mol. Cancer
, vol.8
, pp. 94
-
-
Bhuvaneswari, R.1
Gan, Y.Y.2
Soo, K.C.3
Olivo, M.4
-
28
-
-
79958204380
-
Suppression of bladder cancer cell tumorigenicity in an athymic mouse model by adenoviral vector-mediated transfer of LRIG1
-
Li, F., Ye, Z. Q., Guo, D. S. & Yang, W. M. Suppression of bladder cancer cell tumorigenicity in an athymic mouse model by adenoviral vector-mediated transfer of LRIG1. Oncol. Rep. 26, 439-446 (2011).
-
(2011)
Oncol. Rep.
, vol.26
, pp. 439-446
-
-
Li, F.1
Ye, Z.Q.2
Guo, D.S.3
Yang, W.M.4
-
29
-
-
84904479838
-
EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype
-
Rebouissou, S. et al. EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype. Sci. Transl. Med. 6, 244ra91 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 244ra91
-
-
Rebouissou, S.1
-
30
-
-
84875286224
-
Combined use of anti-VEGF and anti-EGFR monoclonal antibodies with photodynamic therapy suppresses tumor growth in an in vivo tumor model
-
Bhuvaneswari, R., Thong, P., Yuen, G. Y., Olivo, M. & Chee, S. K. Combined use of anti-VEGF and anti-EGFR monoclonal antibodies with photodynamic therapy suppresses tumor growth in an in vivo tumor model. J. Cancer Sci. Ther. 5, 100-105 (2013).
-
(2013)
J. Cancer Sci. Ther.
, vol.5
, pp. 100-105
-
-
Bhuvaneswari, R.1
Thong, P.2
Yuen, G.Y.3
Olivo, M.4
Chee, S.K.5
-
31
-
-
80052868947
-
Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance
-
Quesnelle, K. M. & Grandis, J. R. Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance. Clin. Cancer Res. 17, 5935-5944 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 5935-5944
-
-
Quesnelle, K.M.1
Grandis, J.R.2
-
33
-
-
84860492047
-
CanSAR: An integrated cancer public translational research and drug discovery resource
-
Halling-Brown, M. D. et al. canSAR: an integrated cancer public translational research and drug discovery resource. Nucleic Acids Res. 40, D947-D956 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D947-D956
-
-
Halling-Brown, M.D.1
-
34
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis, C. S. et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N. Engl. J. Med. 359, 1757-1765 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
-
35
-
-
77953434938
-
A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results
-
Pruthi, R. S. et al. A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: clinical and pathological results. BJU Int. 106, 349-354 (2010).
-
(2010)
BJU Int.
, vol.106
, pp. 349-354
-
-
Pruthi, R.S.1
-
36
-
-
66149084012
-
A phase II trial of cisplatin (C), gemcitabine (G) and gefitinib for advanced urothelial tract carcinoma: Results of Cancer and Leukemia Group B (CALGB) 90102
-
Philips, G. K. et al. A phase II trial of cisplatin (C), gemcitabine (G) and gefitinib for advanced urothelial tract carcinoma: results of Cancer and Leukemia Group B (CALGB) 90102. Ann. Oncol. 20, 1074-1079 (2009).
-
(2009)
Ann. Oncol.
, vol.20
, pp. 1074-1079
-
-
Philips, G.K.1
-
37
-
-
84905713382
-
A randomized phase 2 trial of gemcitabine/cisplatin with or without cetuximab in patients with advanced urothelial carcinoma
-
Hussain, M. et al. A randomized phase 2 trial of gemcitabine/cisplatin with or without cetuximab in patients with advanced urothelial carcinoma. Cancer 120, 2684-2693 (2014).
-
(2014)
Cancer
, vol.120
, pp. 2684-2693
-
-
Hussain, M.1
-
38
-
-
75149171017
-
Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium
-
Petrylak, D. P. et al. Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium. BJU Int. 105, 317-321 (2010).
-
(2010)
BJU Int.
, vol.105
, pp. 317-321
-
-
Petrylak, D.P.1
-
39
-
-
84949632229
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00238420 (2015).
-
(2015)
-
-
-
40
-
-
84949632230
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02006667 (2015).
-
(2015)
-
-
-
41
-
-
84949632231
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01828736 (2013).
-
(2013)
-
-
-
42
-
-
84949632232
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01191892 (2012).
-
(2012)
-
-
-
43
-
-
84949632233
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01382706 (2015).
-
(2015)
-
-
-
44
-
-
84949632234
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02013765 (2014).
-
(2014)
-
-
-
45
-
-
84921676709
-
ERBB2 mutations characterize a subgroup of muscle-invasive bladder cancers with excellent response to neoadjuvant chemotherapy
-
Groenendijk, F. H. et al. ERBB2 mutations characterize a subgroup of muscle-invasive bladder cancers with excellent response to neoadjuvant chemotherapy. Eur. Urol. http://dx.doi.org/10.1016/j.eururo.2015.01.014.
-
Eur. Urol
-
-
Groenendijk, F.H.1
-
46
-
-
77955508884
-
Molecular grade (FGFR3/MIB-1) and EORTC risk scores are predictive in primary non-muscle-invasive bladder cancer
-
van Rhijn, B. W. et al. Molecular grade (FGFR3/MIB-1) and EORTC risk scores are predictive in primary non-muscle-invasive bladder cancer. Eur. Urol. 58, 433-441 (2010).
-
(2010)
Eur. Urol.
, vol.58
, pp. 433-441
-
-
Van Rhijn, B.W.1
-
47
-
-
34548407864
-
FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
-
Tomlinson, D. C., Baldo, O., Harnden, P. & Knowles, M. A. FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J. Pathol. 213, 91-98 (2007).
-
(2007)
J. Pathol.
, vol.213
, pp. 91-98
-
-
Tomlinson, D.C.1
Baldo, O.2
Harnden, P.3
Knowles, M.A.4
-
49
-
-
66349135677
-
Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
-
Qing, J. et al. Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J. Clin. Invest. 119, 1216-1229 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1216-1229
-
-
Qing, J.1
-
50
-
-
84880064049
-
Fibroblast growth factor receptor 3 is a rational therapeutic target in bladder cancer
-
Gust, K. M. et al. Fibroblast growth factor receptor 3 is a rational therapeutic target in bladder cancer. Mol. Cancer Ther. 12, 1245-1254 (2013).
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 1245-1254
-
-
Gust, K.M.1
-
51
-
-
84878781242
-
Identification of targetable FGFR gene fusions in diverse cancers
-
Wu, Y. M. et al. Identification of targetable FGFR gene fusions in diverse cancers. Cancer Discov. 3, 636-647 (2013).
-
(2013)
Cancer Discov.
, vol.3
, pp. 636-647
-
-
Wu, Y.M.1
-
52
-
-
78650875209
-
Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo
-
Lamont, F. R. et al. Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo. Br. J. Cancer 104, 75-82 (2011).
-
(2011)
Br. J. Cancer
, vol.104
, pp. 75-82
-
-
Lamont, F.R.1
-
53
-
-
84874500441
-
Fibroblast growth factor receptors-1 and-3 play distinct roles in the regulation of bladder cancer growth and metastasis: Implications for therapeutic targeting
-
Cheng, T. et al. Fibroblast growth factor receptors-1 and-3 play distinct roles in the regulation of bladder cancer growth and metastasis: implications for therapeutic targeting. PLoS ONE 8, e57284 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e57284
-
-
Cheng, T.1
-
54
-
-
84885229945
-
Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer
-
Herrera-Abreu, M. T. et al. Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer. Cancer Discov. 3, 1058-1071 (2013).
-
(2013)
Cancer Discov.
, vol.3
, pp. 1058-1071
-
-
Herrera-Abreu, M.T.1
-
55
-
-
84925225265
-
Phase 2 trial of dovitinib in patients with progressive FGFR3-mutated or FGFR3 wild-type advanced urothelial carcinoma
-
Milowsky, M. I. et al. Phase 2 trial of dovitinib in patients with progressive FGFR3-mutated or FGFR3 wild-type advanced urothelial carcinoma. Eur. J. Cancer 50, 3145-3152 (2014).
-
(2014)
Eur. J. Cancer
, vol.50
, pp. 3145-3152
-
-
Milowsky, M.I.1
-
56
-
-
84907347811
-
Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumors
-
Galsky, M. D. et al. Phase Ib study of dovitinib in combination with gemcitabine plus cisplatin or gemcitabine plus carboplatin in patients with advanced solid tumors. Cancer Chemother. Pharmacol. 74, 465-471 (2014).
-
(2014)
Cancer Chemother. Pharmacol.
, vol.74
, pp. 465-471
-
-
Galsky, M.D.1
-
57
-
-
84949632235
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01732107 (2015).
-
(2015)
-
-
-
58
-
-
27944473690
-
VEGF as a key mediator of angiogenesis in cancer
-
Carmeliet, P. VEGF as a key mediator of angiogenesis in cancer. Oncology 69 (Suppl. 3), 4-10 (2005).
-
(2005)
Oncology
, vol.69
, pp. 4-10
-
-
Carmeliet, P.1
-
59
-
-
77955198725
-
SiRNA-mediated knockdown of VEGF-A, VEGF-C and VEGFR-3 suppresses the growth and metastasis of mouse bladder carcinoma in vivo
-
Feng, W. et al. siRNA-mediated knockdown of VEGF-A, VEGF-C and VEGFR-3 suppresses the growth and metastasis of mouse bladder carcinoma in vivo. Exp. Ther. Med. 1, 899-904 (2010).
-
(2010)
Exp. Ther. Med.
, vol.1
, pp. 899-904
-
-
Feng, W.1
-
60
-
-
79953790937
-
Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer
-
Yang, H. et al. Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer. Mol. Cancer 10, 36 (2011).
-
(2011)
Mol. Cancer
, vol.10
, pp. 36
-
-
Yang, H.1
-
61
-
-
70350096110
-
Construction of a DNA vaccine encoding Flk-1 extracellular domain and C3d fusion gene and investigation of its suppressing effect on tumor growth
-
Liang, P. H. et al. Construction of a DNA vaccine encoding Flk-1 extracellular domain and C3d fusion gene and investigation of its suppressing effect on tumor growth. Cancer Immunol. Immunother. 59, 93-101 (2010).
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, pp. 93-101
-
-
Liang, P.H.1
-
62
-
-
84862557093
-
Phase II trial of neoadjuvant cisplatin, gemcitabine, and bevacizumab followed by radical cystectomy (RC) in patients with muscle-invasive transitional cell carcinoma (TCC) of the bladder
-
abstract 276
-
Chaudhary, U. B. et al. Phase II trial of neoadjuvant cisplatin, gemcitabine, and bevacizumab followed by radical cystectomy (RC) in patients with muscle-invasive transitional cell carcinoma (TCC) of the bladder. J. Clin. Oncol. 29 (Suppl. 7), abstract 276 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
-
-
Chaudhary, U.B.1
-
63
-
-
84860242276
-
Neoadjuvant chemotherapy with DD-MVAC and bevacizumab in high-risk urothelial cancer: Results from a phase II trial at the M. D. Anderson Cancer Center
-
abstract 261
-
Siefker-Radtke, A. O. et al. Neoadjuvant chemotherapy with DD-MVAC and bevacizumab in high-risk urothelial cancer: results from a phase II trial at the M. D. Anderson Cancer Center. J. Clin. Oncol. 30 (Suppl. 5), abstract 261 (2012).
-
(2012)
J. Clin. Oncol.
, pp. 30
-
-
Siefker-Radtke, A.O.1
-
64
-
-
84875722132
-
Phase II study of gemcitabine, carboplatin, and bevacizumab in patients with advanced unresectable or metastatic urothelial cancer
-
Balar, A. V. et al. Phase II study of gemcitabine, carboplatin, and bevacizumab in patients with advanced unresectable or metastatic urothelial cancer. J. Clin. Oncol. 31, 724-730 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 724-730
-
-
Balar, A.V.1
-
65
-
-
84876982362
-
Gemcitabine, cisplatin, and sunitinib for metastatic urothelial carcinoma and as preoperative therapy for muscle-invasive bladder cancer
-
Galsky, M. D. et al. Gemcitabine, cisplatin, and sunitinib for metastatic urothelial carcinoma and as preoperative therapy for muscle-invasive bladder cancer. Clin. Genitourin. Cancer 11, 175-181 (2013).
-
(2013)
Clin. Genitourin. Cancer
, vol.11
, pp. 175-181
-
-
Galsky, M.D.1
-
66
-
-
79955006416
-
Phase II trial of cisplatin, gemcitabine, and bevacizumab as first-line therapy for metastatic urothelial carcinoma: Hoosier Oncology Group GU 04-75
-
Hahn, N. M. et al. Phase II trial of cisplatin, gemcitabine, and bevacizumab as first-line therapy for metastatic urothelial carcinoma: Hoosier Oncology Group GU 04-75. J. Clin. Oncol. 29, 1525-1530 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 1525-1530
-
-
Hahn, N.M.1
-
67
-
-
77950474660
-
Phase II study of sunitinib in patients with metastatic urothelial cancer
-
Gallagher, D. J. et al. Phase II study of sunitinib in patients with metastatic urothelial cancer. J. Clin. Oncol. 28, 1373-1379 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1373-1379
-
-
Gallagher, D.J.1
-
68
-
-
77957756488
-
Phase II study of aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a California Cancer Consortium Trial
-
Twardowski, P. et al. Phase II study of aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a California Cancer Consortium Trial. Urology 76, 923-926 (2010).
-
(2010)
Urology
, vol.76
, pp. 923-926
-
-
Twardowski, P.1
-
69
-
-
84887993264
-
A phase II safety and efficacy study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer
-
Pili, R. et al. A phase II safety and efficacy study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor pazopanib in patients with metastatic urothelial cancer. Clin. Genitourin. Cancer 11, 477-483 (2013).
-
(2013)
Clin. Genitourin. Cancer
, vol.11
, pp. 477-483
-
-
Pili, R.1
-
70
-
-
84864337145
-
Pazopanib in advanced and platinum-resistant urothelial cancer: An open-label, single group, phase 2 trial
-
Necchi, A. et al. Pazopanib in advanced and platinum-resistant urothelial cancer: an open-label, single group, phase 2 trial. Lancet Oncol. 13, 810-816 (2012).
-
(2012)
Lancet Oncol.
, vol.13
, pp. 810-816
-
-
Necchi, A.1
-
71
-
-
84949632236
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00942331 (2015).
-
(2015)
-
-
-
72
-
-
84949632237
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01108055 (2014).
-
(2014)
-
-
-
73
-
-
84949632238
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00794950 (2015).
-
(2015)
-
-
-
74
-
-
63049094489
-
Inactivation of p53 and Pten promotes invasive bladder cancer
-
Puzio-Kuter, A. M. et al. Inactivation of p53 and Pten promotes invasive bladder cancer. Genes Dev. 23, 675-680 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 675-680
-
-
Puzio-Kuter, A.M.1
-
75
-
-
79960088030
-
The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers
-
Makhlin, I. et al. The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers. BJU Int. 108, E84-E90 (2011).
-
(2011)
BJU Int.
, vol.108
, pp. E84-E90
-
-
Makhlin, I.1
-
76
-
-
84884592636
-
PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation
-
Seront, E. et al. PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation. Br. J. Cancer 109, 1586-1592 (2013).
-
(2013)
Br. J. Cancer
, vol.109
, pp. 1586-1592
-
-
Seront, E.1
-
77
-
-
84859601315
-
Urothelial tumor initiation requires deregulation of multiple signaling pathways: Implications in target-based therapies
-
Zhou, H. et al. Urothelial tumor initiation requires deregulation of multiple signaling pathways: Implications in target-based therapies. Carcinogenesis 33, 770-780 (2012).
-
(2012)
Carcinogenesis
, vol.33
, pp. 770-780
-
-
Zhou, H.1
-
78
-
-
84949632239
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01090466 (2012).
-
(2012)
-
-
-
79
-
-
84949632240
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01182168 (2015).
-
(2015)
-
-
-
80
-
-
84949632241
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01215136 (2015).
-
(2015)
-
-
-
81
-
-
84864369495
-
Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: Clinical activity, molecular response, and biomarkers
-
Seront, E. et al. Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers. Ann. Oncol. 23, 2663-2670 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, pp. 2663-2670
-
-
Seront, E.1
-
82
-
-
84868000731
-
A phase II trial of temsirolimus in second-line metastatic urothelial cancer
-
Gerullis, H. et al. A phase II trial of temsirolimus in second-line metastatic urothelial cancer. Med. Oncol. 29, 2870-2876 (2012).
-
(2012)
Med. Oncol.
, vol.29
, pp. 2870-2876
-
-
Gerullis, H.1
-
83
-
-
84880781405
-
Phase II study of everolimus in metastatic urothelial cancer
-
Milowsky, M. I. et al. Phase II study of everolimus in metastatic urothelial cancer. BJU Int. 112, 462-470 (2013).
-
(2013)
BJU Int.
, vol.112
, pp. 462-470
-
-
Milowsky, M.I.1
-
84
-
-
84949632242
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01551030 (2014).
-
(2014)
-
-
-
85
-
-
84904555503
-
Phase i dose-escalation and-expansion study of buparlisib (BKM120), an oral pan-class i PI3K inhibitor, in patients with advanced solid tumors
-
Rodon, J. et al. Phase I dose-escalation and-expansion study of buparlisib (BKM120), an oral pan-class I PI3K inhibitor, in patients with advanced solid tumors. Invest. New Drugs 32, 670-681 (2014).
-
(2014)
Invest. New Drugs
, vol.32
, pp. 670-681
-
-
Rodon, J.1
-
86
-
-
84949632243
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01259063 (2015).
-
(2015)
-
-
-
87
-
-
77955018234
-
Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells
-
Harada, Y. et al. Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells. Cancer Res. 70, 5829-5839 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5829-5839
-
-
Harada, Y.1
-
88
-
-
77950300277
-
Potent cytotoxic effect of a novel nuclear factor-κB inhibitor dehydroxymethylepoxyquinomicin on human bladder cancer cells producing various cytokines
-
Kodaira, K. et al. Potent cytotoxic effect of a novel nuclear factor-κB inhibitor dehydroxymethylepoxyquinomicin on human bladder cancer cells producing various cytokines. Urology 75, 805-812 (2010).
-
(2010)
Urology
, vol.75
, pp. 805-812
-
-
Kodaira, K.1
-
89
-
-
79953212611
-
A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-κ B and generating reactive oxygen species
-
Shanmugam, R. et al. A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-κ B and generating reactive oxygen species. Int. J. Cancer 128, 2481-2494 (2011).
-
(2011)
Int. J. Cancer
, vol.128
, pp. 2481-2494
-
-
Shanmugam, R.1
-
90
-
-
84866431328
-
Targeting Stat3 abrogates EGFR inhibitor resistance in cancer
-
Sen, M. et al. Targeting Stat3 abrogates EGFR inhibitor resistance in cancer. Clin. Cancer Res. 18, 4986-4996 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 4986-4996
-
-
Sen, M.1
-
91
-
-
84859059272
-
Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells
-
Zhu, J. et al. Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells. Cell Signal. 24, 1323-1332 (2012).
-
(2012)
Cell Signal.
, vol.24
, pp. 1323-1332
-
-
Zhu, J.1
-
92
-
-
84862146158
-
Androgen receptor signaling regulates cell growth and vulnerability to doxorubicin in bladder cancer
-
Shiota, M. et al. Androgen receptor signaling regulates cell growth and vulnerability to doxorubicin in bladder cancer. J. Urol. 188, 276-286 (2012).
-
(2012)
J. Urol.
, vol.188
, pp. 276-286
-
-
Shiota, M.1
-
93
-
-
77950299628
-
Androgen receptor is a potential therapeutic target for bladder cancer
-
Wu, J. T., Han, B. M., Yu, S. Q., Wang, H. P. & Xia, S. J. Androgen receptor is a potential therapeutic target for bladder cancer. Urology 75, 820-827 (2010).
-
(2010)
Urology
, vol.75
, pp. 820-827
-
-
Wu, J.T.1
Han, B.M.2
Yu, S.Q.3
Wang, H.P.4
Xia, S.J.5
-
94
-
-
84920279836
-
Androgen receptor inducing bladder cancer progression by promoting an epithelial-mesenchymal transition
-
Jitao, W. et al. Androgen receptor inducing bladder cancer progression by promoting an epithelial-mesenchymal transition. Andrologia 46, 1128-1133 (2014).
-
(2014)
Andrologia
, vol.46
, pp. 1128-1133
-
-
Jitao, W.1
-
95
-
-
79957899607
-
CD24 offers a therapeutic target for control of bladder cancer metastasis based on a requirement for lung colonization
-
Overdevest, J. B. et al. CD24 offers a therapeutic target for control of bladder cancer metastasis based on a requirement for lung colonization. Cancer Res. 71, 3802-3811 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 3802-3811
-
-
Overdevest, J.B.1
-
96
-
-
77950233381
-
Inhibition of bladder tumour growth by histone deacetylase inhibitor
-
Ozawa, A. et al. Inhibition of bladder tumour growth by histone deacetylase inhibitor. BJU Int. 105, 1181-1186 (2010).
-
(2010)
BJU Int.
, vol.105
, pp. 1181-1186
-
-
Ozawa, A.1
-
97
-
-
34247637194
-
Promotion of bladder cancer development and progression by androgen receptor signals
-
Miyamoto, H. et al. Promotion of bladder cancer development and progression by androgen receptor signals. J. Natl Cancer Inst. 99, 558-568 (2007).
-
(2007)
J. Natl Cancer Inst.
, vol.99
, pp. 558-568
-
-
Miyamoto, H.1
-
98
-
-
84871372488
-
CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated
-
Overdevest, J. B. et al. CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated. Proc. Natl Acad. Sci. USA 109, E3588-E3596 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. E3588-E3596
-
-
Overdevest, J.B.1
-
99
-
-
84877099149
-
The investigational aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo
-
Zhou, N. et al. The investigational aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo. Clin. Cancer Res. 19, 1717-1728 (2013).
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 1717-1728
-
-
Zhou, N.1
-
100
-
-
84949632244
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02109328 (2014).
-
(2014)
-
-
-
101
-
-
0034902711
-
What we could do now: Molecular pathology of bladder cancer
-
Knowles, M. What we could do now: molecular pathology of bladder cancer. Mol. Pathol. 54, 215-221 (2001).
-
(2001)
Mol. Pathol.
, vol.54
, pp. 215-221
-
-
Knowles, M.1
-
102
-
-
0034995205
-
Mutations in apoptosis genes: A pathogenetic factor for human disease
-
Müllauer, L. et al. Mutations in apoptosis genes: a pathogenetic factor for human disease. Mutat. Res. 488, 211-231 (2001).
-
(2001)
Mutat. Res.
, vol.488
, pp. 211-231
-
-
Müllauer, L.1
-
103
-
-
84881077064
-
P53-stabilizing agent CP-31398 prevents growth and invasion of urothelial cancer of the bladder in transgenic UPII-SV40T mice
-
Madka, V. et al. p53-stabilizing agent CP-31398 prevents growth and invasion of urothelial cancer of the bladder in transgenic UPII-SV40T mice. Neoplasia 15, 966-974 (2013).
-
(2013)
Neoplasia
, vol.15
, pp. 966-974
-
-
Madka, V.1
-
104
-
-
0033565558
-
Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma
-
Zhang, Z. et al. Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma. Cancer Res. 59, 3512-3517 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 3512-3517
-
-
Zhang, Z.1
-
105
-
-
12144290526
-
A soluble single-chain T-cell receptor IL-2 fusion protein retains MHC-restricted peptide specificity and IL-2 bioactivity
-
Card, K. et al. A soluble single-chain T-cell receptor IL-2 fusion protein retains MHC-restricted peptide specificity and IL-2 bioactivity. Cancer Immunol. Immunother. 53, 345-357 (2004).
-
(2004)
Cancer Immunol. Immunother.
, vol.53
, pp. 345-357
-
-
Card, K.1
-
106
-
-
84949632245
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01326871 (2015).
-
(2015)
-
-
-
107
-
-
84949632246
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01625260 (2015).
-
(2015)
-
-
-
108
-
-
84884187921
-
Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma
-
Yoshimine, S. et al. Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma. Br. J. Cancer 11, 2312-2320 (2013).
-
(2013)
Br. J. Cancer
, vol.11
, pp. 2312-2320
-
-
Yoshimine, S.1
-
109
-
-
0037249506
-
Expression and prognostic significance of LIVIN, SURVIVIN and other apoptosis-related genes in the progression of superficial bladder cancer
-
Gazzaniga, P. et al. Expression and prognostic significance of LIVIN, SURVIVIN and other apoptosis-related genes in the progression of superficial bladder cancer. Ann. Oncol. 14, 85-90 (2003).
-
(2003)
Ann. Oncol.
, vol.14
, pp. 85-90
-
-
Gazzaniga, P.1
-
110
-
-
78049381635
-
Antisense oligonucleotide targeting livin induces apoptosis of human bladder cancer cell via a mechanism involving caspase 3
-
Liu, C. A. et al. Antisense oligonucleotide targeting livin induces apoptosis of human bladder cancer cell via a mechanism involving caspase 3. J. Exp. Clin. Cancer Res. 29, 63 (2010).
-
(2010)
J. Exp. Clin. Cancer Res.
, vol.29
, pp. 63
-
-
Liu, C.A.1
-
111
-
-
84878986697
-
Translation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonization
-
Wang, H. et al. Translation initiation factor eIF3b expression in human cancer and its role in tumor growth and lung colonization. Clin. Cancer Res. 19, 2850-2860 (2013).
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 2850-2860
-
-
Wang, H.1
-
112
-
-
78650102883
-
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences
-
Amit, D. & Hochberg, A. Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences. J. Transl. Med. 8, 134 (2010).
-
(2010)
J. Transl. Med.
, vol.8
, pp. 134
-
-
Amit, D.1
Hochberg, A.2
-
113
-
-
79958025545
-
Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P3 and IGF2-P4 regulatory sequences
-
Amit, D., Tamir, S., Birman, T., Gofrit, O. N. & Hochberg, A. Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P3 and IGF2-P4 regulatory sequences. Int. J. Clin. Exp. Med. 4, 91-102 (2011).
-
(2011)
Int. J. Clin. Exp. Med.
, vol.4
, pp. 91-102
-
-
Amit, D.1
Tamir, S.2
Birman, T.3
Gofrit, O.N.4
Hochberg, A.5
-
114
-
-
84949632247
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00903708 (2012).
-
(2012)
-
-
-
115
-
-
34848901974
-
Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity
-
Graff, J. R. et al. Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity. J. Clin. Invest. 117, 2638-2648 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2638-2648
-
-
Graff, J.R.1
-
116
-
-
38849180436
-
Targeting the eukaryotic translation initiation factor 4E for cancer therapy
-
Graff, J. R., Konicek, B. W., Carter, J. H. & Marcusson, E. G. Targeting the eukaryotic translation initiation factor 4E for cancer therapy. Cancer Res. 68, 631-634 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 631-634
-
-
Graff, J.R.1
Konicek, B.W.2
Carter, J.H.3
Marcusson, E.G.4
-
117
-
-
84892423233
-
Epidermal growth factor enhances androgen receptor-mediated bladder cancer progression and invasion via potentiation of AR transactivation
-
Hsieh, T. F. et al. Epidermal growth factor enhances androgen receptor-mediated bladder cancer progression and invasion via potentiation of AR transactivation. Oncol. Rep. 30, 2917-2922 (2013).
-
(2013)
Oncol. Rep.
, vol.30
, pp. 2917-2922
-
-
Hsieh, T.F.1
-
118
-
-
80054114844
-
A phase 1 dose escalation, pharmacokinetic, and pharmacodynamic evaluation of eIF-4E antisense oligonucleotide LY2275796 in patients with advanced cancer
-
Hong, D. S. et al. A phase 1 dose escalation, pharmacokinetic, and pharmacodynamic evaluation of eIF-4E antisense oligonucleotide LY2275796 in patients with advanced cancer. Clin. Cancer Res. 17, 6582-6591 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6582-6591
-
-
Hong, D.S.1
-
119
-
-
84869215008
-
FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth
-
Du, X. et al. FGFR3 stimulates stearoyl CoA desaturase 1 activity to promote bladder tumor growth. Cancer Res. 72, 5843-5855 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 5843-5855
-
-
Du, X.1
-
120
-
-
67650064783
-
A critical role for choline kinase-α in the aggressiveness of bladder carcinomas
-
Hernando, E. et al. A critical role for choline kinase-α in the aggressiveness of bladder carcinomas. Oncogene 28, 2425-2435 (2009).
-
(2009)
Oncogene
, vol.28
, pp. 2425-2435
-
-
Hernando, E.1
-
121
-
-
84878862969
-
Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: Evidence in human tumor-derived cell lines and mouse xenografts
-
de la Cueva, A. et al. Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts. PLoS ONE 8, e64961 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e64961
-
-
De La Cueva, A.1
-
122
-
-
84949632248
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01215864 (2014).
-
(2014)
-
-
-
123
-
-
84866609922
-
Screening of well-established drugs targeting cancer metabolism: Reproducibility of the efficacy of a highly effective drug combination in mice
-
Abolhassani, M. et al. Screening of well-established drugs targeting cancer metabolism: Reproducibility of the efficacy of a highly effective drug combination in mice. Invest. New Drugs 30, 1331-1342 (2012).
-
(2012)
Invest. New Drugs
, vol.30
, pp. 1331-1342
-
-
Abolhassani, M.1
-
124
-
-
84856515477
-
Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: Experimental results and case report
-
Guais, A. et al. Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report. Invest. New Drugs 30, 200-211 (2012).
-
(2012)
Invest. New Drugs
, vol.30
, pp. 200-211
-
-
Guais, A.1
-
125
-
-
84893856177
-
Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging
-
Allen, M. D. et al. Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging. Cancer Res. 74, 896-907 (2014).
-
(2014)
Cancer Res.
, vol.74
, pp. 896-907
-
-
Allen, M.D.1
-
126
-
-
84893735507
-
CD40 ligand and tdTomato-armed vaccinia virus for induction of antitumor immune response and tumor imaging
-
Parviainen, S. et al. CD40 ligand and tdTomato-armed vaccinia virus for induction of antitumor immune response and tumor imaging. Gene Ther. 21, 195-204 (2014).
-
(2014)
Gene Ther.
, vol.21
, pp. 195-204
-
-
Parviainen, S.1
-
127
-
-
84890471598
-
Targeting plasminogen activator inhibitor-1 inhibits angiogenesis and tumor growth in a human cancer xenograft model
-
Gomes-Giacoia, E., Miyake, M., Goodison, S. & Rosser, C. J. Targeting plasminogen activator inhibitor-1 inhibits angiogenesis and tumor growth in a human cancer xenograft model. Mol. Cancer Ther. 12, 2697-2708 (2013).
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 2697-2708
-
-
Gomes-Giacoia, E.1
Miyake, M.2
Goodison, S.3
Rosser, C.J.4
-
128
-
-
84868257627
-
CD24 is an effector of HIF-1-driven primary tumor growth and metastasis
-
Thomas, S. et al. CD24 is an effector of HIF-1-driven primary tumor growth and metastasis. Cancer Res. 72, 5600-5612 (2012).
-
(2012)
Cancer Res.
, vol.72
, pp. 5600-5612
-
-
Thomas, S.1
-
129
-
-
59449103002
-
A novel cancer therapy by skin delivery of indoleamine 2, 3-dioxygenase siRNA
-
Yen, M. C. et al. A novel cancer therapy by skin delivery of indoleamine 2, 3-dioxygenase siRNA. Clin. Cancer Res. 15, 641-649 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 641-649
-
-
Yen, M.C.1
-
130
-
-
80555139618
-
Additive antitumoral effect of interleukin-12 gene therapy and chemotherapy in the treatment of urothelial bladder cancer in vitro and in vivo
-
Liu, W., Cao, Y., Fernandez, M. I., Niu, H. & Xiu, Y. Additive antitumoral effect of interleukin-12 gene therapy and chemotherapy in the treatment of urothelial bladder cancer in vitro and in vivo. Int. Urol. Nephrol. 43, 721-727 (2011).
-
(2011)
Int. Urol. Nephrol.
, vol.43
, pp. 721-727
-
-
Liu, W.1
Cao, Y.2
Fernandez, M.I.3
Niu, H.4
Xiu, Y.5
-
131
-
-
84928468444
-
Emerging immunotherapies for bladder cancer
-
Kim, J. W., Tomita, Y., Trepel, J. & Apolo, A. B. Emerging immunotherapies for bladder cancer. Curr. Opin. Oncol. 27, 191-200 (2015).
-
(2015)
Curr. Opin. Oncol.
, vol.27
, pp. 191-200
-
-
Kim, J.W.1
Tomita, Y.2
Trepel, J.3
Apolo, A.B.4
-
132
-
-
84923078390
-
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
-
Powles, T. et al. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 515, 3558-62 (2014).
-
(2014)
Nature
, vol.515
, pp. 3558-3562
-
-
Powles, T.1
-
133
-
-
84926419796
-
Could MPDL3280A offer a therapeutic breakthrough in metastatic bladder cancer?
-
Fenner, A. Could MPDL3280A offer a therapeutic breakthrough in metastatic bladder cancer? Nat. Rev. Urol. 12, 61 (2015).
-
(2015)
Nat. Rev. Urol.
, vol.12
, pp. 61
-
-
Fenner, A.1
-
134
-
-
84949632249
-
-
U. S. Food and Drug Administration. fda.gov [online]
-
U. S. Food and Drug Administration. fda.gov [online], http://www.fda.gov/RegulatoryInformation/Legislation/SignificantAmendmentstotheFDCAct/FDASIA/ucm329491.htm (2015).
-
(2015)
-
-
-
135
-
-
84949632250
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02108652 (2015).
-
(2015)
-
-
-
136
-
-
84949632251
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02302807 (2015).
-
(2015)
-
-
-
137
-
-
84949632252
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02351739 (2015).
-
(2015)
-
-
-
138
-
-
84949632253
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02256436 (2015).
-
(2015)
-
-
-
139
-
-
84949632254
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02335424 (2015).
-
(2015)
-
-
-
140
-
-
84949632255
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02324582 (2015).
-
(2015)
-
-
-
141
-
-
84949632256
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT01928394 (2015).
-
(2015)
-
-
-
142
-
-
84949632257
-
-
US National Library of Medicine. ClinicalTrials.gov [online]
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02387996 (2015).
-
(2015)
-
-
-
143
-
-
84892551595
-
Combined therapeutic effects of adenoviral vector-mediated GLIPR1 gene therapy and radiotherapy in prostate and bladder cancer models
-
Fujita, T. et al. Combined therapeutic effects of adenoviral vector-mediated GLIPR1 gene therapy and radiotherapy in prostate and bladder cancer models. Urol. Oncol. 32, 92-100 (2014).
-
(2014)
Urol. Oncol.
, vol.32
, pp. 92-100
-
-
Fujita, T.1
-
144
-
-
84895070947
-
Enhanced antitumor efficacy of integrin-targeted oncolytic adenovirus AxdAdB3-F/RGD on bladder cancer
-
Wang, H. et al. Enhanced antitumor efficacy of integrin-targeted oncolytic adenovirus AxdAdB3-F/RGD on bladder cancer. Urology 83, 508.e513-508.e519 (2014).
-
(2014)
Urology
, vol.83
, pp. 508e513-508e519
-
-
Wang, H.1
-
145
-
-
84878614614
-
Viruses in cancer treatment
-
Alemany, R. Viruses in cancer treatment. Clin. Transl. Oncol. 15, 182-188 (2013).
-
(2013)
Clin. Transl. Oncol.
, vol.15
, pp. 182-188
-
-
Alemany, R.1
-
146
-
-
84933526132
-
From virotherapy to oncolytic immunotherapy: Where are we now?
-
Coffin, R. S. From virotherapy to oncolytic immunotherapy: where are we now? Curr. Opin. Virol. 13, 93-100 (2015).
-
(2015)
Curr. Opin. Virol.
, vol.13
, pp. 93-100
-
-
Coffin, R.S.1
-
147
-
-
84895536864
-
Armed therapeutic viruses-A disruptive therapy on the horizon of cancer immunotherapy
-
Bauzon, M. & Hermiston, T. Armed therapeutic viruses-a disruptive therapy on the horizon of cancer immunotherapy. Front. Immunol. 5, 1-10 (2014).
-
(2014)
Front. Immunol.
, vol.5
, pp. 1-10
-
-
Bauzon, M.1
Hermiston, T.2
-
148
-
-
84869095632
-
A first human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer
-
Burke, J. M. et al. A first human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer. J. Urol. 188, 2391-2397 (2012).
-
(2012)
J. Urol.
, vol.188
, pp. 2391-2397
-
-
Burke, J.M.1
-
149
-
-
84859102997
-
Tyrosine kinase receptor inhibitor-targeted combined chemotherapy for metastatic bladder cancer
-
Wu, C. L., Ping, S. Y., Yu, C. P. & Yu, D. S. Tyrosine kinase receptor inhibitor-targeted combined chemotherapy for metastatic bladder cancer. Kaohsiung J. Med. Sci. 28, 194-203 (2012).
-
(2012)
Kaohsiung J. Med. Sci.
, vol.28
, pp. 194-203
-
-
Wu, C.L.1
Ping, S.Y.2
Yu, C.P.3
Yu, D.S.4
-
150
-
-
84929054410
-
The differential expression of EphB2 and EphB4 receptor kinases in normal bladder and in transitional cell carcinoma of the bladder
-
Li, X. et al. The differential expression of EphB2 and EphB4 receptor kinases in normal bladder and in transitional cell carcinoma of the bladder. PloS One 9, e105326 (2014).
-
(2014)
PloS One
, vol.9
, pp. e105326
-
-
Li, X.1
-
151
-
-
84904750908
-
The effects of STAT3 and survivin silencing on the growth of human bladder carcinoma cells
-
Zhang, B., Lu, Z., Hou, Y., Hu, J. & Wang, C. The effects of STAT3 and survivin silencing on the growth of human bladder carcinoma cells. Tumour Biol. 35, 5401-5407 (2014).
-
(2014)
Tumour Biol.
, vol.35
, pp. 5401-5407
-
-
Zhang, B.1
Lu, Z.2
Hou, Y.3
Hu, J.4
Wang, C.5
-
152
-
-
84907588664
-
Targeting of α-v integrins reduces malignancy of bladder carcinoma
-
van der Horst, G. et al. Targeting of α-v integrins reduces malignancy of bladder carcinoma. PLoS ONE 9, e108464 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e108464
-
-
Van Der Horst, G.1
-
153
-
-
85041813459
-
Improving bioscience research reporting: The ARRIVE guidelines for reporting animal research
-
Kilkenny, C., Browne, W. J., Cuthill, I. C., Emerson, M. & Altman, D. G. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol. 8, e1000412 (2010).
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000412
-
-
Kilkenny, C.1
Browne, W.J.2
Cuthill, I.C.3
Emerson, M.4
Altman, D.G.5
-
154
-
-
84893726404
-
Two years later: Journals are not yet enforcing the ARRIVE guidelines on reporting standards for pre-clinical animal studies
-
Baker, D., Lidster, K., Sottomayor, A. & Amor, S. Two years later: journals are not yet enforcing the ARRIVE guidelines on reporting standards for pre-clinical animal studies. PLoS Biol. 12, e1001756 (2014).
-
(2014)
PLoS Biol.
, vol.12
, pp. e1001756
-
-
Baker, D.1
Lidster, K.2
Sottomayor, A.3
Amor, S.4
-
155
-
-
84864601712
-
A comparison of cancer burden and research spending reveals discrepancies in the distribution of research funding
-
Carter, A. J. & Nguyen, C. N. A comparison of cancer burden and research spending reveals discrepancies in the distribution of research funding. BMC Public Health 12, 526 (2012).
-
(2012)
BMC Public Health
, vol.12
, pp. 526
-
-
Carter, A.J.1
Nguyen, C.N.2
-
156
-
-
84896729356
-
Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway
-
Joung, Y. H. et al. Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway. Int. J. Oncol. 44, 883-895 (2014).
-
(2014)
Int. J. Oncol.
, vol.44
, pp. 883-895
-
-
Joung, Y.H.1
-
157
-
-
61349185227
-
In vitro and in vivo inhibitory effect evaluation of cyclooxygenase-2 inhibitors, antisense cyclooxygenase-2 cDNA, and their combination on the growth of human bladder cancer cells
-
Qin, J. et al. In vitro and in vivo inhibitory effect evaluation of cyclooxygenase-2 inhibitors, antisense cyclooxygenase-2 cDNA, and their combination on the growth of human bladder cancer cells. Biomed. Pharmacother. 63, 241-248 (2009).
-
(2009)
Biomed. Pharmacother.
, vol.63
, pp. 241-248
-
-
Qin, J.1
-
158
-
-
57249096979
-
Intravesical administration of plasminogen activator inhibitor type-1 inhibits in vivo bladder tumor invasion and progression
-
Chen, S. C., Henry, D. O., Hicks, D. G., Reczek, P. R. & Wong, M. K. Intravesical administration of plasminogen activator inhibitor type-1 inhibits in vivo bladder tumor invasion and progression. J. Urol. 181, 336-342 (2009).
-
(2009)
J. Urol.
, vol.181
, pp. 336-342
-
-
Chen, S.C.1
Henry, D.O.2
Hicks, D.G.3
Reczek, P.R.4
Wong, M.K.5
-
159
-
-
78649773966
-
Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion
-
Bhattacharya, A. et al. Allyl isothiocyanate-rich mustard seed powder inhibits bladder cancer growth and muscle invasion. Carcinogenesis 31, 2105-2110 (2010).
-
(2010)
Carcinogenesis
, vol.31
, pp. 2105-2110
-
-
Bhattacharya, A.1
-
160
-
-
84863028426
-
The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl) cysteine, inhibits the growth and muscle invasion of bladder cancer
-
Bhattacharya, A., Li, Y., Geng, F., Munday, R. & Zhang, Y. The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl) cysteine, inhibits the growth and muscle invasion of bladder cancer. Carcinogenesis 33, 394-398 (2012).
-
(2012)
Carcinogenesis
, vol.33
, pp. 394-398
-
-
Bhattacharya, A.1
Li, Y.2
Geng, F.3
Munday, R.4
Zhang, Y.5
-
161
-
-
79960906404
-
Small interfering RNA targeting integrin-linked kinase inhibited the growth and induced apoptosis in human bladder cancer cells
-
Gao, J. et al. Small interfering RNA targeting integrin-linked kinase inhibited the growth and induced apoptosis in human bladder cancer cells. Int. J. Biochem. Cell Biol. 43, 1294-1304 (2011).
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 1294-1304
-
-
Gao, J.1
-
162
-
-
80051474820
-
ShRNA targeting PLCε inhibits bladder cancer cell growth in vitro and in vivo
-
Cheng, H. et al. shRNA targeting PLCε inhibits bladder cancer cell growth in vitro and in vivo. Urology 78, e7-e11 (2011).
-
(2011)
Urology
, vol.78
, pp. e7-e11
-
-
Cheng, H.1
-
163
-
-
84902178629
-
Thrombomodulin expression regulates tumorigenesis in bladder cancer
-
Wu, C. T., Chang, Y. H., Lin, P., Chen, W. C. & Chen, M. F. Thrombomodulin expression regulates tumorigenesis in bladder cancer. BMC Cancer 14, 375 (2014).
-
(2014)
BMC Cancer
, vol.14
, pp. 375
-
-
Wu, C.T.1
Chang, Y.H.2
Lin, P.3
Chen, W.C.4
Chen, M.F.5
-
164
-
-
71049173726
-
Heat-shock protein 70-72 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumour progression and promotes migration and invasion
-
Garg, M. et al. Heat-shock protein 70-72 (HSP70-2) expression in bladder urothelial carcinoma is associated with tumour progression and promotes migration and invasion. Eur. J. Cancer 46, 207-215 (2010).
-
(2010)
Eur. J. Cancer
, vol.46
, pp. 207-215
-
-
Garg, M.1
-
165
-
-
84892422200
-
The impact of the receptor of hyaluronan-mediated motility (RHAMM) on human urothelial transitional cell cancer of the bladder
-
Niedworok, C. et al. The impact of the receptor of hyaluronan-mediated motility (RHAMM) on human urothelial transitional cell cancer of the bladder. PLoS ONE 8, e75681 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e75681
-
-
Niedworok, C.1
-
166
-
-
84873660557
-
A novel mechanism of PPAR γ induction via EGFR signalling constitutes rational for combination therapy in bladder cancer
-
Mansure, J. J. et al. A novel mechanism of PPAR γ induction via EGFR signalling constitutes rational for combination therapy in bladder cancer. PLoS ONE 8, e55997 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e55997
-
-
Mansure, J.J.1
-
167
-
-
78650350269
-
Effect of nitroxoline on angiogenesis and growth of human bladder cancer
-
Shim, J. S. et al. Effect of nitroxoline on angiogenesis and growth of human bladder cancer. J. Natl Cancer Inst. 102, 1855-1873 (2010).
-
(2010)
J. Natl Cancer Inst.
, vol.102
, pp. 1855-1873
-
-
Shim, J.S.1
-
168
-
-
79955952869
-
Cyclooxygenase 2-dependent and independent activation of Akt through casein kinase 2 contributes to human bladder cancer cell survival
-
Shimada, K., Anai, S., Marco, D. A., Fujimoto, K. & Konishi, N. Cyclooxygenase 2-dependent and independent activation of Akt through casein kinase 2 contributes to human bladder cancer cell survival. BMC Urol. 11, 8 (2011).
-
(2011)
BMC Urol.
, vol.11
, pp. 8
-
-
Shimada, K.1
Anai, S.2
Marco, D.A.3
Fujimoto, K.4
Konishi, N.5
-
169
-
-
68849099328
-
Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer
-
Matsui, Y. et al. Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer. Mol. Cancer Ther. 8, 2402-2411 (2009).
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2402-2411
-
-
Matsui, Y.1
-
170
-
-
77149132132
-
Activation of nerve growth factor-induced B α by methylene-substituted diindolynmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth
-
Cho, S. D. et al. Activation of nerve growth factor-induced B α by methylene-substituted diindolynmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth. Mol. Pharmacol. 77, 396-404 (2010).
-
(2010)
Mol. Pharmacol.
, vol.77
, pp. 396-404
-
-
Cho, S.D.1
-
171
-
-
84891904422
-
Intravesical instillation of c-MYC inhibitor KSI-3716 suppresses orthotopic bladder tumor growth
-
Jeong, K. C. et al. Intravesical instillation of c-MYC inhibitor KSI-3716 suppresses orthotopic bladder tumor growth. J. Urol. 191, 510-518 (2014).
-
(2014)
J. Urol.
, vol.191
, pp. 510-518
-
-
Jeong, K.C.1
-
172
-
-
77956636408
-
A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor
-
Ding, S. et al. A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor. J. Urol. 184, 1175-1181 (2010).
-
(2010)
J. Urol.
, vol.184
, pp. 1175-1181
-
-
Ding, S.1
-
173
-
-
84906266052
-
Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter
-
Seo, H. K. et al. Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter. Oncotarget 5, 5615-5623 (2014).
-
(2014)
Oncotarget
, vol.5
, pp. 5615-5623
-
-
Seo, H.K.1
-
174
-
-
79955572694
-
RNAi-based therapeutics targeting survivin and PLK1 for treatment of bladder cancer
-
Seth, S. et al. RNAi-based therapeutics targeting survivin and PLK1 for treatment of bladder cancer. Mol. Ther. 19, 928-935 (2011).
-
(2011)
Mol. Ther.
, vol.19
, pp. 928-935
-
-
Seth, S.1
-
175
-
-
71849097523
-
Role of syndecan-1 (CD138) in cell survival of human urothelial carcinoma
-
Shimada, K. et al. Role of syndecan-1 (CD138) in cell survival of human urothelial carcinoma. Cancer Sci. 101, 155-160 (2010).
-
(2010)
Cancer Sci.
, vol.101
, pp. 155-160
-
-
Shimada, K.1
-
176
-
-
84887765144
-
Inhibition of nitric oxide is a good therapeutic target for bladder tumors that express iNOS
-
Belgorosky, D. et al. Inhibition of nitric oxide is a good therapeutic target for bladder tumors that express iNOS. Nitric Oxide 36, 11-18 (2014).
-
(2014)
Nitric Oxide
, vol.36
, pp. 11-18
-
-
Belgorosky, D.1
-
177
-
-
84885420703
-
+ T cell
-
+ T cell. Tumor Biol. 34, 2863-2869 (2013).
-
(2013)
Tumor Biol.
, vol.34
, pp. 2863-2869
-
-
Han, C.1
-
178
-
-
84896505509
-
TGF-β-induced upregulation of malat1 promotes bladder cancer metastasis by associating with suz12
-
Fan, Y. et al. TGF-β-induced upregulation of malat1 promotes bladder cancer metastasis by associating with suz12. Clin. Cancer Res. 20, 1531-1541 (2014).
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 1531-1541
-
-
Fan, Y.1
-
179
-
-
85027957698
-
A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells
-
Lin, C. C. et al. A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells. Cancer Immunol. Immunother. 60, 1019-1027 (2011).
-
(2011)
Cancer Immunol. Immunother.
, vol.60
, pp. 1019-1027
-
-
Lin, C.C.1
-
180
-
-
84904254200
-
FGFR3 translocations in bladder cancer: Differential sensitivity to HSP90 inhibition based on drug metabolism
-
Acquaviva, J. et al. FGFR3 translocations in bladder cancer: differential sensitivity to HSP90 inhibition based on drug metabolism. Mol. Cancer Res. 12, 1042-1054 (2014).
-
(2014)
Mol. Cancer Res.
, vol.12
, pp. 1042-1054
-
-
Acquaviva, J.1
-
181
-
-
84922162501
-
Combined CDKN1A/TP53 mutation in bladder cancer is a therapeutic target
-
Liu, Y. & Kwiatkowski, D. J. Combined CDKN1A/TP53 mutation in bladder cancer is a therapeutic target. Mol. Cancer Ther. 14, 174-182 (2015).
-
(2015)
Mol. Cancer Ther.
, vol.14
, pp. 174-182
-
-
Liu, Y.1
Kwiatkowski, D.J.2
-
182
-
-
77952174698
-
Dasatinib is preclinically active against Src-overexpressing human transitional cell carcinoma of the urothelium with activated Src signaling
-
Levitt, J. M., Yamashita, H., Jian, W., Lerner, S. P. & Sonpavde, G. Dasatinib is preclinically active against Src-overexpressing human transitional cell carcinoma of the urothelium with activated Src signaling. Mol. Cancer Ther. 9, 1128-1135 (2010).
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 1128-1135
-
-
Levitt, J.M.1
Yamashita, H.2
Jian, W.3
Lerner, S.P.4
Sonpavde, G.5
-
183
-
-
77950687263
-
Growth delay of human bladder cancer cells by prostate stem cell antigen downregulation is associated with activation of immune signaling pathways
-
Marra, E. et al. Growth delay of human bladder cancer cells by prostate stem cell antigen downregulation is associated with activation of immune signaling pathways. BMC Cancer 10, 129 (2010).
-
(2010)
BMC Cancer
, vol.10
, pp. 129
-
-
Marra, E.1
-
184
-
-
84878161187
-
RNA interference targeting adrenomedullin induces apoptosis and reduces the growth of human bladder urothelial cell carcinoma
-
Liu, A. G. et al. RNA interference targeting adrenomedullin induces apoptosis and reduces the growth of human bladder urothelial cell carcinoma. Med. Oncol. 30, 616 (2013).
-
(2013)
Med. Oncol.
, vol.30
, pp. 616
-
-
Liu, A.G.1
-
185
-
-
84870308901
-
The inhibition of human bladder cancer growth by calcium carbonate/CaIP6 nanocomposite particles delivering AIB1 siRNA
-
Wei, J. et al. The inhibition of human bladder cancer growth by calcium carbonate/CaIP6 nanocomposite particles delivering AIB1 siRNA. Biomaterials 34, 1246-1254 (2013).
-
(2013)
Biomaterials
, vol.34
, pp. 1246-1254
-
-
Wei, J.1
-
186
-
-
84862792644
-
MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins
-
Chen, H. et al. MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins. Cancer Lett. 320, 40-47 (2012).
-
(2012)
Cancer Lett.
, vol.320
, pp. 40-47
-
-
Chen, H.1
-
187
-
-
79960124328
-
Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells
-
Zhou, H. et al. Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells. Mol. Cancer Ther. 10, 1276-1288 (2011).
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 1276-1288
-
-
Zhou, H.1
-
188
-
-
84878684130
-
Overexpression of immunoglobulin G prompts cell proliferation and inhibits cell apoptosis in human urothelial carcinoma
-
Liang, P. Y. et al. Overexpression of immunoglobulin G prompts cell proliferation and inhibits cell apoptosis in human urothelial carcinoma. Tumor Biol. 34, 1783-1791 (2013).
-
(2013)
Tumor Biol.
, vol.34
, pp. 1783-1791
-
-
Liang, P.Y.1
-
189
-
-
84899021999
-
Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α
-
Zhao, W. et al. Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α. J. Biol. Chem. 289, 11219-11229 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 11219-11229
-
-
Zhao, W.1
-
190
-
-
84904723632
-
Replication-competent adenovirus expressing TRAIL synergistically potentiates the antitumor effect of gemcitabine in bladder cancer cells
-
Mao, L. et al. Replication-competent adenovirus expressing TRAIL synergistically potentiates the antitumor effect of gemcitabine in bladder cancer cells. Tumour Biol. 35, 5937-5944 (2014).
-
(2014)
Tumour Biol.
, vol.35
, pp. 5937-5944
-
-
Mao, L.1
-
191
-
-
84905441209
-
BCMab1, a monoclonal antibody against aberrantly glycosylated integrin α3β1, has potent antitumor activity of bladder cancer in vivo
-
Li, C. et al. BCMab1, a monoclonal antibody against aberrantly glycosylated integrin α3β1, has potent antitumor activity of bladder cancer in vivo. Clin. Cancer Res. 20, 4001-4013 (2014).
-
(2014)
Clin. Cancer Res.
, vol.20
, pp. 4001-4013
-
-
Li, C.1
-
192
-
-
84859719825
-
RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration
-
Said, N., Sanchez-Carbayo, M., Smith, S. C. & Theodorescu, D. RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration. J. Clin. Invest. 122, 1503-1518 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1503-1518
-
-
Said, N.1
Sanchez-Carbayo, M.2
Smith, S.C.3
Theodorescu, D.4
-
193
-
-
84920733820
-
A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas
-
Foulks, J. M. et al. A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas. Neoplasia 16, 403-412 (2014).
-
(2014)
Neoplasia
, vol.16
, pp. 403-412
-
-
Foulks, J.M.1
-
194
-
-
84921712127
-
Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer
-
Zhao, F. et al. Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer. Oncotarget 6, 1064-1078 (2015).
-
(2015)
Oncotarget
, vol.6
, pp. 1064-1078
-
-
Zhao, F.1
|