Development and in vivo evaluation of an implantable nano-enabled multipolymeric scaffold for the management of AIDS dementia complex (ADC)

International Journal of Pharmaceutics

Volumn 496, Issue 2, 2015, Pages 863-877

  Harilall, Sheri Lee ^a   Choonara, Yahya E ^a   Tomar, Lomas Kumar ^a   Tyagi, Charu ^a   Kumar, Pradeep ^a   Du Toit, Lisa C ^a   Modi, Girish ^a   Naidoo, Dinesh ^a   Iyuke, Sunny E ^b   Danckwerts, Michael P ^a   Pillay, Viness ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

AIDS dementia complex management; Implantable device; Nanoparticles; Polymeric scaffold

Indexed keywords

MOLECULAR SCAFFOLD; PLACEBO; POLYMER; ZIDOVUDINE; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL THERAPY; ARTICLE; BRAIN TISSUE; COLLOID; CONTROLLED STUDY; DRUG DELIVERY DEVICE; DRUG RELEASE; EQUIPMENT DESIGN; FRONTAL LOBE; HIV ASSOCIATED DEMENTIA; IMPLANTABLE MULTIPOLYMERIC DRUG DELIVERY DEVICE; IN VITRO STUDY; IN VIVO STUDY; MALE; MECHANICS; NANOFABRICATION; NANOPHARMACEUTICS; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RAT; WEIGHT REDUCTION; ZETA POTENTIAL; AIDS DEMENTIA COMPLEX; ANIMAL; BRAIN; CHEMISTRY; DEVICES; DRUG DELIVERY SYSTEM; HUMAN; INFRARED SPECTROSCOPY; MEDICINAL CHEMISTRY; PATHOLOGY; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; SPRAGUE DAWLEY RAT; TISSUE SCAFFOLD;

AIDS DEMENTIA COMPLEX; ANIMALS; BRAIN; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; HUMANS; MALE; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TISSUE SCAFFOLDS; ZIDOVUDINE;

EID: 84949599715     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.10.025     Document Type: Article

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