Multiple Origins of Mutations in the mdr1 Gene—A Putative Marker of Chloroquine Resistance in P. vivax

PLoS Neglected Tropical Diseases

Volumn 9, Issue 11, 2015, Pages

  Schousboe, Mette L ^a   Ranjitkar, Samir ^a   Rajakaruna, Rupika S ^b   Amerasinghe, Priyanie H ^c   Morales, Francisco ^d   Pearce, Richard ^e   Ord, Rosalyn ^f   Leslie, Toby ^e   Rowland, Mark ^e   Gadalla, Nahla B ^g   Konradsen, Flemming ^a   Bygbjerg, Ib C ^a   Roper, Cally ^e   Alifrangis, Michael ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF PERADENIYA   (Sri Lanka)

^c INTERNATIONAL WATER MANAGEMENT INSTITUTE   (India)

^d UNIVERSIDAD SAN FRANCISCO DE QUITO   (Ecuador)

^e LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^f NEW YORK BLOOD CENTER   (United States)

^g NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; GENOMIC DNA; MULTIDRUG RESISTANCE PROTEIN 1; ANTIMALARIAL AGENT; MDR1 PROTEIN, PLASMODIUM VIVAX; MICROSATELLITE DNA; MULTIDRUG RESISTANCE PROTEIN; PROTOZOAL PROTEIN;

ALLELE; ANIMAL TISSUE; ARTICLE; CODON; DNA FLANKING REGION; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MUTATION; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; HAPLOTYPE; HETEROZYGOSITY; MICROSATELLITE MARKER; MULTIDRUG RESISTANCE PROTEIN 1 GENE; NONHUMAN; PLASMODIUM VIVAX; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ASIA; DRUG EFFECTS; DRUG RESISTANCE; ECUADOR; GENETIC SELECTION; GENETICS; GENOTYPE; HUMAN; MUTATION; PHYLOGEOGRAPHY; SUDAN;

ANTIMALARIALS; ASIA; CHLOROQUINE; DRUG RESISTANCE; ECUADOR; GENOTYPE; HUMANS; MICROSATELLITE REPEATS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PHYLOGEOGRAPHY; PLASMODIUM VIVAX; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTOZOAN PROTEINS; SELECTION, GENETIC; SUDAN;

EID: 84949579803     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0004196     Document Type: Article

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