Reduced variation around drug-resistant dhfr alleles in African Plasmodium falciparum

Molecular Biology and Evolution

Volumn 22, Issue 9, 2005, Pages 1834-1844

  Pearce, Richard ^a   Malisa, Allen ^b,c   Kachur, S Patrick ^c,d   Barnes, Karen ^e   Sharp, Brian ^f   Roper, Cally ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b Department of Biological Sciences   (Tanzania)

^c IFAKARA HEALTH INSTITUTE   (Tanzania)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^e UNIVERSITY OF CAPE TOWN   (South Africa)

^f SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

Plasmodium falciparum; Pyrimethamine resistance; Selective sweeps

Indexed keywords

FANSIDAR;

ALLELE; ARTICLE; BITE; CHROMOSOME; CHROMOSOME ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DHFR GENE; DRUG SENSITIVITY; DRUG USE; GENE; GENETIC RECOMBINATION; GENETIC SELECTION; GENETIC VARIABILITY; HUMAN; INOCULATION; MALARIA; MARKER GENE; MEASUREMENT; NONHUMAN; PLASMODIUM FALCIPARUM; POPULATION; RETROSPECTIVE STUDY; SOUTH AFRICA;

AFRICA; ALLELES; ANIMALS; ANTIMALARIALS; DRUG COMBINATIONS; DRUG RESISTANCE; GENE FREQUENCY; GENES, PROTOZOAN; GENOME, PROTOZOAN; HUMANS; MALARIA, FALCIPARUM; MICROSATELLITE REPEATS; MUTATION; PLASMODIUM FALCIPARUM; PYRIMETHAMINE; RECOMBINATION, GENETIC; RETROSPECTIVE STUDIES; SELECTION (GENETICS); SULFADOXINE; VARIATION (GENETICS);

PLASMODIUM FALCIPARUM;

EID: 23944440692     PISSN: 07374038     EISSN: None     Source Type: Journal    
DOI: 10.1093/molbev/msi177     Document Type: Article

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