Use of macrophages to deliver therapeutic and imaging contrast agents to tumors

Biomaterials

Volumn 33, Issue 16, 2012, Pages 4195-4203

  Choi, Jinhyang ^a   Kim, Hye Yeong ^a   Ju, Eun Jin ^a   Jung, Joohee ^a   Park, Jaesook ^a   Chung, Hye Kyung ^b   Lee, Jin Seong ^a   Lee, Jung Shin ^a   Park, Heon Joo ^c   Song, Si Yeol ^a   Jeong, Seong Yun ^a   Choi, Eun Kyung ^a,b  

^a University of Ulsan College of Medicine   (South Korea)

^b Asan Medical Center   (South Korea)

^c Inha University School of Medicine   (South Korea)

Author keywords

Drug delivery; Liposomal doxorubicin; Macrophage; Tumor target

Indexed keywords

ADMINISTRATION SYSTEM; BIOCARRIER; DOXORUBICIN; DRUG-TARGETING; IMAGING CONTRAST; IN-VIVO; LIPOSOMAL DOXORUBICIN; MONOCYTES/MACROPHAGES; MR IMAGING; PERITONEAL MACROPHAGE; SYSTEMIC ADMINISTRATION; THERAPEUTIC EFFECTS; THERAPEUTIC EFFICACY; TROJAN HORSE; TUMOR CELLS; TUMOR GROWTH; TUMOR MODELS; TUMOR SITE; TUMOR TISSUES;

BLOOD VESSELS; DISEASES; DRUG DELIVERY; IRON OXIDES; LIPOSOMES; MACROPHAGES; MAGNETIC RESONANCE IMAGING; PHOSPHOLIPIDS;

TUMORS;

CONTRAST MEDIUM; DOXORUBICIN; IRON OXIDE; LIPOSOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL; CANCER CELL; CANCER GROWTH; CANCER THERAPY; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENCAPSULATION; HYPOXIA; MACROPHAGE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL MOVEMENT; CONTRAST MEDIA; DOXORUBICIN; HUMANS; MACROPHAGES, PERITONEAL; MAGNETIC RESONANCE IMAGING; MICE; NEOPLASMS;

EQUIDAE;

EID: 84862819070     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.02.022     Document Type: Article

References (29)

1. Brown D.M. Drug delivery systems in cancer therapy 2004, Humana Press Inc., Totowa.
2. Portney N.G., Ozkan M. Nano-oncology: drug delivery, imaging, and sensing. Anal Bioanal Chem 2006, 384:620-630.
3. Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 2005, 5:161-171.
4. Haley B., Frenkel E. Nanoparticles for drug delivery in cancer treatment. Urol Oncol 2008, 26:57-64.
5. Davis M.E., Chen Z.G., Shin D.M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat Rev Drug Discov 2008, 7:771-782.
6. Batrakova E.V., Gendelman H.E., Kabanov A.V. Cell-mediated drug delivery. Expert Opin Drug Deliv 2011, 8:415-433.
7. Dou H., Destache C.J., Morehead J.R., Mosley R.L., Boska M.D., Kingsley J., et al. Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery. Blood 2006, 108:2827-2835.
8. Sica A., Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 2007, 117:1155-1166.
9. Lewis C.E., Pollard J.W. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006, 66:605-612.
10. Takahashi K. Development and differentiation of macrophages and their related cells. Hum Cell 1994, 7:109-115.
11. Solinas G., Germano G., Mantovani A., Allavena P. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol 2009, 86:1065-1073.
12. Lewis C., Murdoch C. Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies. Am J Pathol 2005, 167:627-635.
13. Wilson W.R., Hay M.P. Targeting hypoxia in cancer therapy. Nat Rev Cancer 2011, 11:393-410.
14. Espey M.G. Tumor macrophage redox and effector mechanisms associated with hypoxia. Free Radic Biol Med 2006, 41:1621-1628.
15. Choi M.R., Stanton-Maxey K.J., Stanley J.K., Levin C.S., Bardhan R., Akin D., et al. A cellular Trojan Horse for delivery of therapeutic nanoparticles into tumors. Nano Lett 2007, 7:3759-3765.
16. Madsen S.J., Baek S.K., Makkouk A.R., Krasieva T., Hirschberg H. Macrophages as cell-based delivery systems for nanoshells in photothermal therapy. Ann Biomed Eng 2011, [Epub ahead of print].
17. Dou H., Grotepas C.B., McMillan J.M., Destache C.J., Chaubal M., Werling J., et al. Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS. J Immunol 2009, 183:661-669.
18. Muthana M., Giannoudis A., Scott S.D., Fang H.Y., Coffelt S.B., Morrow F.J., et al. Use of macrophages to target therapeutic adenovirus to human prostate tumors. Cancer Res 2011, 71:1805-1815.
19. Ghassabeh G.H., De Baetselier P., Brys L., Noel W., Van Ginderachter J.A., Meerschaut S., et al. Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Blood 2006, 108:575-583.
20. Hou Z., Falcone D.J., Subbaramaiah K., Dannenberg A.J. Macrophages induce COX-2 expression in breast cancer cells: role of IL-1β autoamplification. Carcinogenesis 2011, 32:695-702.
21. Takeda N., O'Dea E.L., Doedens A., Kim J.W., Weidemann A., Stockmann C., et al. Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis. Genes Dev 2010, 24:491-501.
22. Bressani R.F., Nowacek A.S., Singh S., Balkundi S., Rabinow B., McMillan J., et al. Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage. Nanotoxicology 2011, 5:592-605.
23. Ikehara Y., Niwa T., Biao L., Ikehara S.K., Ohashi N., Kobayashi T., et al. A carbohydrate recognition-based drug delivery and controlled release system using intraperitoneal macrophages as a cellular vehicle. Cancer Res 2006, 66:8740-8748.
24. Puri A., Loomis K., Smith B., Lee J.H., Yavlovich A., Heldman E., et al. Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic. Crit Rev Ther Drug Carier Syst 2009, 26:523-580.
25. Fossheim S.L., Il'yasov K.A., Hennig J., Bjornerud A. Thermosensitive paramagnetic liposomes for temperature control during MR imaging-guided hyperthermia: in vitro feasibility studies. Acad Radiol 2000, 7:1107-1115.
26. de Smet M., Langereis S., van den Bosch S., Grull H. Temperature-sensitive liposomes for doxorubicin delivery under MRI guidance. J Control Release 2010, 143:120-127.
27. Needham D., Anyarambhatla G., Kong G., Dewhirst M.W. A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model. Cancer Res 2000, 60:1197-1201.
28. Kong G., Anyarambhatla G., Petros W.P., Braun R.D., Colvin O.M., Needham D., et al. Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. Cancer Res 2000, 60:6950-6957.
29. Yarmolenko P.S., Zhao Y., Landon C., Spasojevic I., Yuan F., Needham D., et al. Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours. Int J Hyperthermia 2010, 26:485-498.