Aldosterone down-regulates the slowly activated delayed rectifier potassium current in adult Guinea pig cardiomyocytes

British Journal of Pharmacology

Volumn 172, Issue 23, 2015, Pages 5596-5608

  Lv, Yankun ^a,b   Bai, Song ^a   Zhang, Hua ^a   Zhang, Hongxue ^a   Meng, Jing ^a   Li, Li ^b   Xu, Yanfang ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; DELAYED RECTIFIER POTASSIUM CHANNEL; GLASS; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; SPIRONOLACTONE; POTASSIUM CHANNEL BLOCKING AGENT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; GENE EXPRESSION; GUINEA PIG; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART PAPILLARY MUSCLE; HEART REPOLARIZATION; HEART VENTRICLE; HORMONE ACTION; IN VITRO STUDY; MALE; MICROELECTRODE; NONHUMAN; OSMOTIC PUMP; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QT PROLONGATION; TISSUE SECTION; WHOLE CELL PATCH CLAMP; ANIMAL; ANTAGONISTS AND INHIBITORS; CARDIAC MUSCLE CELL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ALDOSTERONE; ANIMALS; DELAYED RECTIFIER POTASSIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GUINEA PIGS; INJECTIONS, SUBCUTANEOUS; MALE; MYOCYTES, CARDIAC; POTASSIUM CHANNEL BLOCKERS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84949531129     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13163     Document Type: Article

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