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Volumn 50, Issue 12, 2015, Pages 1197-1205

Effect of branched-chain amino acid supplementation on functional liver regeneration in patients undergoing portal vein embolization and sequential hepatectomy: a randomized controlled trial

Author keywords

Branched chain amino acids; Functional liver regeneration; Liver uptake value; Major hepatectomy; Portal vein embolization

Indexed keywords

ALBUMIN; BRANCHED CHAIN AMINO ACID; HUMAN SERUM ALBUMIN TC 99M; ISOLEUCINE; LEUCINE; VALINE; MACROSALB TC 99M; PENTETATE TECHNETIUM TC 99M; RADIOPHARMACEUTICAL AGENT; TECHNETIUM TC 99M DTPA-GALACTOSYL-HUMAN SERUM ALBUMIN;

EID: 84949531075     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-015-1067-y     Document Type: Article
Times cited : (40)

References (42)
  • 1
    • 0033752004 scopus 로고    scopus 로고
    • Percutaneous portal vein embolization increases the feasibility and safety of major liver resection for hepatocellular carcinoma in injured liver
    • COI: 1:STN:280:DC%2BD3crhtF2qsQ%3D%3D, PID: 11066138
    • Azoulay D, Castaing D, Krissat J, et al. Percutaneous portal vein embolization increases the feasibility and safety of major liver resection for hepatocellular carcinoma in injured liver. Ann Surg. 2000;232:665–72.
    • (2000) Ann Surg , vol.232 , pp. 665-672
    • Azoulay, D.1    Castaing, D.2    Krissat, J.3
  • 2
    • 0037315694 scopus 로고    scopus 로고
    • Portal vein embolization before right hepatectomy: prospective clinical trial
    • PID: 12560779
    • Farges O, Belghiti J, Kianmanesh R, et al. Portal vein embolization before right hepatectomy: prospective clinical trial. Ann Surg. 2003;237:208–17.
    • (2003) Ann Surg , vol.237 , pp. 208-217
    • Farges, O.1    Belghiti, J.2    Kianmanesh, R.3
  • 3
    • 33644636165 scopus 로고    scopus 로고
    • Two hundred forty consecutive portal vein embolizations before extended hepatectomy for biliary cancer: surgical outcome and long-term follow-up
    • PID: 16495702
    • Nagino M, Kamiya J, Nishio H, et al. Two hundred forty consecutive portal vein embolizations before extended hepatectomy for biliary cancer: surgical outcome and long-term follow-up. Ann Surg. 2006;243:364–72.
    • (2006) Ann Surg , vol.243 , pp. 364-372
    • Nagino, M.1    Kamiya, J.2    Nishio, H.3
  • 4
    • 70349431193 scopus 로고    scopus 로고
    • Volumetric and functional recovery of the remnant liver after major liver resection with prior portal vein embolization : recovery after PVE and liver resection
    • PID: 19475462
    • van den Esschert JW, de Graaf W, van Lienden KP, et al. Volumetric and functional recovery of the remnant liver after major liver resection with prior portal vein embolization: recovery after PVE and liver resection. J Gastrointest Surg. 2009;13:1464–9.
    • (2009) J Gastrointest Surg , vol.13 , pp. 1464-1469
    • van den Esschert, J.W.1    de Graaf, W.2    van Lienden, K.P.3
  • 5
    • 0026033871 scopus 로고
    • Human liver regeneration after major hepatectomy. A study of liver volume by computed tomography
    • COI: 1:STN:280:DyaK3M7ltFWmtw%3D%3D, PID: 1998403
    • Chen MF, Hwang TL, Hung CF. Human liver regeneration after major hepatectomy. A study of liver volume by computed tomography. Ann Surg. 1991;213:227–9.
    • (1991) Ann Surg , vol.213 , pp. 227-229
    • Chen, M.F.1    Hwang, T.L.2    Hung, C.F.3
  • 6
    • 84880132795 scopus 로고    scopus 로고
    • Percentage of future liver remnant volume before portal vein embolization influences the degree of liver regeneration after hepatectomy
    • PID: 23715651
    • Okabe H, Beppu T, Nakagawa S, et al. Percentage of future liver remnant volume before portal vein embolization influences the degree of liver regeneration after hepatectomy. J Gastrointest Surg. 2013;17:1447–51.
    • (2013) J Gastrointest Surg , vol.17 , pp. 1447-1451
    • Okabe, H.1    Beppu, T.2    Nakagawa, S.3
  • 7
    • 37649009511 scopus 로고    scopus 로고
    • 99mTc-GSA scintigraphy with SPECT for assessment of hepatic function and functional volume during liver regeneration in a rat model of partial hepatectomy
    • PID: 18077537
    • 99mTc-GSA scintigraphy with SPECT for assessment of hepatic function and functional volume during liver regeneration in a rat model of partial hepatectomy. J Nucl Med. 2008;49:122–8.
    • (2008) J Nucl Med , vol.49 , pp. 122-128
    • de Graaf, W.1    Vetelainen, R.L.2    de Bruin, K.3
  • 8
    • 70349671217 scopus 로고    scopus 로고
    • Three hundred and one consecutive extended right hepatectomies: evaluation of outcome based on systematic liver volumetry
    • Kishi Y, Abdalla EK, Chun YS, et al. Three hundred and one consecutive extended right hepatectomies: evaluation of outcome based on systematic liver volumetry. Ann Surg. 2009;25:540–8.
    • (2009) Ann Surg , vol.25 , pp. 540-548
    • Kishi, Y.1    Abdalla, E.K.2    Chun, Y.S.3
  • 9
    • 33645666489 scopus 로고    scopus 로고
    • Platelet derived serotonin mediates liver regeneration
    • COI: 1:CAS:528:DC%2BD28XjtFalsL0%3D, PID: 16601191
    • Lesurtel M, Graf R, Aleil B, et al. Platelet derived serotonin mediates liver regeneration. Science. 2006;312:104–7.
    • (2006) Science , vol.312 , pp. 104-107
    • Lesurtel, M.1    Graf, R.2    Aleil, B.3
  • 10
    • 0142155141 scopus 로고    scopus 로고
    • Hepatic regeneration in living donor liver transplantation
    • Olthoff KM. Hepatic regeneration in living donor liver transplantation. Liver Transplant. 2003;9(10 Suppl 2):S35–41.
    • (2003) Liver Transplant , vol.9 , pp. S35-S41
    • Olthoff, K.M.1
  • 11
    • 79960296425 scopus 로고    scopus 로고
    • 99mTc-galactosyl human serum albumin scintigraphy SPECT–computed tomography fusion system
    • PID: 21523415
    • 99mTc-galactosyl human serum albumin scintigraphy SPECT–computed tomography fusion system. J Gastroenterol. 2011;46:938–43.
    • (2011) J Gastroenterol , vol.46 , pp. 938-943
    • Beppu, T.1    Hayashi, H.2    Okabe, H.3
  • 12
    • 84863215754 scopus 로고    scopus 로고
    • Fused 99m-Tc-GSA SPECT/CT imaging for the preoperative evaluation of postoperative liver function: can the liver uptake index predict postoperative hepatic functional reserve?
    • PID: 22302293
    • Yoshida M, Shiraishi S, Sakaguchi F, et al. Fused 99m-Tc-GSA SPECT/CT imaging for the preoperative evaluation of postoperative liver function: can the liver uptake index predict postoperative hepatic functional reserve? Jpn J Radiol. 2012;30:255–62.
    • (2012) Jpn J Radiol , vol.30 , pp. 255-262
    • Yoshida, M.1    Shiraishi, S.2    Sakaguchi, F.3
  • 13
    • 84865978978 scopus 로고    scopus 로고
    • 99mTc GSA SPECT/CT 3D fused images to evaluate severe fibrosis in patients with chronic liver disease
    • PID: 22492469
    • 99mTc GSA SPECT/CT 3D fused images to evaluate severe fibrosis in patients with chronic liver disease. Jpn J Radiol. 2012;30:435–41.
    • (2012) Jpn J Radiol. , vol.30 , pp. 435-441
    • Yoshida, M.1    Shiraishi, S.2    Sakaguchi, F.3
  • 14
    • 79955466140 scopus 로고    scopus 로고
    • Increase in future remnant liver function after preoperative portal vein embolization
    • PID: 21484773
    • de Graaf W, van Lienden KP, van den Esschert JW, et al. Increase in future remnant liver function after preoperative portal vein embolization. Br J Surg. 2011;98:825–34.
    • (2011) Br J Surg , vol.98 , pp. 825-834
    • de Graaf, W.1    van Lienden, K.P.2    van den Esschert, J.W.3
  • 15
    • 0035123681 scopus 로고    scopus 로고
    • Functional hepatic volume measured by technetium-99m-galactosyl-human serum albumin liver scintigraphy: comparison between hepatocyte volume and liver volume by computed tomography
    • COI: 1:STN:280:DC%2BD3M7ot12msA%3D%3D, PID: 11232703
    • Kwon AH, Matsui Y, Ha-Kawa SK, et al. Functional hepatic volume measured by technetium-99m-galactosyl-human serum albumin liver scintigraphy: comparison between hepatocyte volume and liver volume by computed tomography. Am J Gastroenterol. 2001;96:541–6.
    • (2001) Am J Gastroenterol , vol.96 , pp. 541-546
    • Kwon, A.H.1    Matsui, Y.2    Ha-Kawa, S.K.3
  • 16
    • 84888088346 scopus 로고    scopus 로고
    • Branched-chain amino acids in liver diseases
    • COI: 1:CAS:528:DC%2BC2cXjvFaqtLo%3D, PID: 24282351
    • Tajiri K, Shimizu Y. Branched-chain amino acids in liver diseases. World J Gastroenterol. 2013;19:7620–9.
    • (2013) World J Gastroenterol , vol.19 , pp. 7620-7629
    • Tajiri, K.1    Shimizu, Y.2
  • 17
    • 33745727871 scopus 로고    scopus 로고
    • Overweight and obesity increase the risk for liver cancer in patients with liver cirrhosis and long-term oral supplementation with branched-chain amino acid granules inhibits liver carcinogenesis in heavier patients with liver cirrhosis
    • COI: 1:CAS:528:DC%2BD28XmslGqtb4%3D, PID: 16737844
    • Muto Y, Sato S, Watanabe A, et al. Overweight and obesity increase the risk for liver cancer in patients with liver cirrhosis and long-term oral supplementation with branched-chain amino acid granules inhibits liver carcinogenesis in heavier patients with liver cirrhosis. Hepatol Res. 2006;35:204–14.
    • (2006) Hepatol Res , vol.35 , pp. 204-214
    • Muto, Y.1    Sato, S.2    Watanabe, A.3
  • 18
    • 84879262070 scopus 로고    scopus 로고
    • Oral supplementation of branched-chain amino acids reduces early recurrence after hepatic resection in patients with hepatocellular carcinoma: a prospective study
    • COI: 1:CAS:528:DC%2BC3sXps1ynsrs%3D, PID: 22890582
    • Ichikawa K, Okabayashi T, Maeda H, et al. Oral supplementation of branched-chain amino acids reduces early recurrence after hepatic resection in patients with hepatocellular carcinoma: a prospective study. Surg Today. 2013;43:720–6.
    • (2013) Surg Today , vol.43 , pp. 720-726
    • Ichikawa, K.1    Okabayashi, T.2    Maeda, H.3
  • 19
    • 83355176160 scopus 로고    scopus 로고
    • Effects of branched-chain amino acid infusions on liver regeneration and plasma amino acid patterns in partially hepatectomized rats
    • COI: 1:CAS:528:DC%2BC3MXhs1yntb%2FJ, PID: 21937393
    • Kim SJ, Kim DG, Lee MD. Effects of branched-chain amino acid infusions on liver regeneration and plasma amino acid patterns in partially hepatectomized rats. Hepatogastroenterology. 2011;58:1280–5.
    • (2011) Hepatogastroenterology , vol.58 , pp. 1280-1285
    • Kim, S.J.1    Kim, D.G.2    Lee, M.D.3
  • 20
    • 0346996345 scopus 로고    scopus 로고
    • Significance of branched chain amino acids as possible stimulators of hepatocyte growth factor
    • COI: 1:CAS:528:DC%2BD3sXpvVWmtbk%3D, PID: 14684177
    • Tomiya T, Omata M, Fujiwara K. Significance of branched chain amino acids as possible stimulators of hepatocyte growth factor. Biochem Biophys Res Commun. 2004;313:411–6.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 411-416
    • Tomiya, T.1    Omata, M.2    Fujiwara, K.3
  • 21
    • 0032706215 scopus 로고    scopus 로고
    • Prospective randomized control study on the effect of branched chain amino acids in patients with liver resection for hepatocellular carcinoma
    • COI: 1:STN:280:DC%2BD3c%2FhvFCjsg%3D%3D, PID: 10553972
    • Meng WC, Leung KL, Ho RL, et al. Prospective randomized control study on the effect of branched chain amino acids in patients with liver resection for hepatocellular carcinoma. Aust N Z J Surg. 1999;69:811–5.
    • (1999) Aust N Z J Surg , vol.69 , pp. 811-815
    • Meng, W.C.1    Leung, K.L.2    Ho, R.L.3
  • 22
    • 79954438223 scopus 로고    scopus 로고
    • Oral supplementation with carbohydrate- and branched-chain amino acid-enriched nutrients improves postoperative quality of life in patients undergoing hepatic resection
    • COI: 1:CAS:528:DC%2BC3MXjsFGjtbk%3D, PID: 20852905
    • Okabayashi T, Iyoki M, Sugimoto T, et al. Oral supplementation with carbohydrate- and branched-chain amino acid-enriched nutrients improves postoperative quality of life in patients undergoing hepatic resection. Amino Acids. 2011;40:1213–20.
    • (2011) Amino Acids , vol.40 , pp. 1213-1220
    • Okabayashi, T.1    Iyoki, M.2    Sugimoto, T.3
  • 23
    • 84949532698 scopus 로고    scopus 로고
    • Hepatectomy and elemental nutrition
    • (in Japanese)
    • Katsuragawa H, Yamamoto M. Hepatectomy and elemental nutrition. Jpn J Med Pharm Sci. 2007;57:121–5 (in Japanese).
    • (2007) Jpn J Med Pharm Sci , vol.57 , pp. 121-125
    • Katsuragawa, H.1    Yamamoto, M.2
  • 24
    • 77949272174 scopus 로고    scopus 로고
    • A new approach to percutaneous transhepatic portal embolization using ethanolamine oleate iopamidol
    • PID: 19821004
    • Beppu T, Iwatsuki M, Okabe H, et al. A new approach to percutaneous transhepatic portal embolization using ethanolamine oleate iopamidol. J Gastroenterol. 2009;45:211–7.
    • (2009) J Gastroenterol , vol.45 , pp. 211-217
    • Beppu, T.1    Iwatsuki, M.2    Okabe, H.3
  • 25
    • 84906345570 scopus 로고    scopus 로고
    • Remnant liver volume-based predictors of postoperative liver dysfunction after hepatectomy: analysis of 625 consecutive patients from a single institution
    • PID: 23860603
    • Okabe H, Beppu T, Chikamoto A, et al. Remnant liver volume-based predictors of postoperative liver dysfunction after hepatectomy: analysis of 625 consecutive patients from a single institution. Int J Clin Oncol. 2014;19:614–21.
    • (2014) Int J Clin Oncol , vol.19 , pp. 614-621
    • Okabe, H.1    Beppu, T.2    Chikamoto, A.3
  • 26
    • 84860572429 scopus 로고    scopus 로고
    • Liver hanging maneuver decrease blood loss and operative time in a right-side hepatectomy
    • PID: 22353521
    • Beppu T, Ishiko T, Chikamoto A, et al. Liver hanging maneuver decrease blood loss and operative time in a right-side hepatectomy. Hepatogastroenterology. 2012;59:542–5.
    • (2012) Hepatogastroenterology , vol.59 , pp. 542-545
    • Beppu, T.1    Ishiko, T.2    Chikamoto, A.3
  • 27
    • 0031685246 scopus 로고    scopus 로고
    • Preoperative evaluation of hepatic functional reserve following hepatectomy by technetium-99m galactosyl human serum albumin liver scintigraphy and computed tomography
    • COI: 1:STN:280:DyaK1M%2FjsFKrsA%3D%3D, PID: 9818276
    • Mitsumori A, Nagaya I, Kimoto S, et al. Preoperative evaluation of hepatic functional reserve following hepatectomy by technetium-99m galactosyl human serum albumin liver scintigraphy and computed tomography. Eur J Nucl Med. 1998;25:1377–82.
    • (1998) Eur J Nucl Med , vol.25 , pp. 1377-1382
    • Mitsumori, A.1    Nagaya, I.2    Kimoto, S.3
  • 29
    • 80053610863 scopus 로고    scopus 로고
    • Preoperative portal vein embolization (PVE) for patients with hepatocellular carcinoma can improve resectability and may improve disease-free survival
    • PID: 21520093
    • Okabe H, Beppu T, Ishiko T, et al. Preoperative portal vein embolization (PVE) for patients with hepatocellular carcinoma can improve resectability and may improve disease-free survival. J Surg Oncol. 2011;104:641–6.
    • (2011) J Surg Oncol , vol.104 , pp. 641-646
    • Okabe, H.1    Beppu, T.2    Ishiko, T.3
  • 30
    • 84919432705 scopus 로고    scopus 로고
    • Functional assessment versus conventional volumetric assessment in the prediction of operative outcomes after major hepatectomy
    • PID: 25482462
    • Hayashi H, Beppu T, Okabe H, et al. Functional assessment versus conventional volumetric assessment in the prediction of operative outcomes after major hepatectomy. Surgery. 2015;157:20–6.
    • (2015) Surgery , vol.157 , pp. 20-26
    • Hayashi, H.1    Beppu, T.2    Okabe, H.3
  • 31
    • 79960843029 scopus 로고    scopus 로고
    • Prognostic impact of preoperative the branched-chain amino acid to the tyrosine ratio in hepatocellular carcinoma patients after initial hepatectomy
    • PID: 21607795
    • Mizuguchi T, Kawamoto M, Meguro M, et al. Prognostic impact of preoperative the branched-chain amino acid to the tyrosine ratio in hepatocellular carcinoma patients after initial hepatectomy. J Gastrointest Surg. 2011;15:1433–9.
    • (2011) J Gastrointest Surg , vol.15 , pp. 1433-1439
    • Mizuguchi, T.1    Kawamoto, M.2    Meguro, M.3
  • 32
    • 34347363025 scopus 로고    scopus 로고
    • Effect of a late evening snack on outpatients with liver cirrhosis
    • COI: 1:CAS:528:DC%2BD2sXptlGqt70%3D, PID: 17517075
    • Aoyama K, Tsuchiya M, Mori K, et al. Effect of a late evening snack on outpatients with liver cirrhosis. Hepatol Res. 2007;37:608–14.
    • (2007) Hepatol Res , vol.37 , pp. 608-614
    • Aoyama, K.1    Tsuchiya, M.2    Mori, K.3
  • 33
    • 84857347318 scopus 로고    scopus 로고
    • Late evening snack: exploiting a period of anabolic opportunity in cirrhosis
    • COI: 1:CAS:528:DC%2BC38Xltlaks7k%3D, PID: 22004479
    • Tsien CD, McCullough AJ, Dasarathy S. Late evening snack: exploiting a period of anabolic opportunity in cirrhosis. J Gastroenterol Hepatol. 2012;27:430–41.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 430-441
    • Tsien, C.D.1    McCullough, A.J.2    Dasarathy, S.3
  • 34
    • 0021783405 scopus 로고
    • Effect of branched chain amino acids on liver regeneration after partial hepatectomy
    • COI: 1:CAS:528:DyaL28XkvFKr, PID: 2932755
    • Holecek M, Simek J, Kruf M, et al. Effect of branched chain amino acids on liver regeneration after partial hepatectomy. Physiol Bohemoslov. 1985;34:359–66.
    • (1985) Physiol Bohemoslov , vol.34 , pp. 359-366
    • Holecek, M.1    Simek, J.2    Kruf, M.3
  • 35
    • 84865503158 scopus 로고    scopus 로고
    • Branched-chain amino acid-enriched nutrients improve nutritional and metabolic abnormalities in the early post-transplant period after living donor liver transplantation
    • PID: 21947604
    • Yoshida R, Yagi T, Sadamori H, et al. Branched-chain amino acid-enriched nutrients improve nutritional and metabolic abnormalities in the early post-transplant period after living donor liver transplantation. J Hepatobiliary Pancreat Sci. 2012;19:438–48.
    • (2012) J Hepatobiliary Pancreat Sci , vol.19 , pp. 438-448
    • Yoshida, R.1    Yagi, T.2    Sadamori, H.3
  • 36
    • 77951667943 scopus 로고    scopus 로고
    • Preoperative oral supplementation with carbohydrate and branched-chain amino acid-enriched nutrient improves insulin resistance in patients undergoing a hepatectomy: a randomized clinical trial using an artificial pancreas
    • COI: 1:CAS:528:DC%2BC3cXjt1eqs7o%3D, PID: 19399583
    • Okabayashi T, Nishimori I, Yamashita K, et al. Preoperative oral supplementation with carbohydrate and branched-chain amino acid-enriched nutrient improves insulin resistance in patients undergoing a hepatectomy: a randomized clinical trial using an artificial pancreas. Amino Acids. 2010;38:901–7.
    • (2010) Amino Acids , vol.38 , pp. 901-907
    • Okabayashi, T.1    Nishimori, I.2    Yamashita, K.3
  • 37
    • 67349195436 scopus 로고    scopus 로고
    • Branched-chain amino acid suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats
    • COI: 1:CAS:528:DC%2BD1MXlslCrtrY%3D, PID: 19319465
    • Yoshiji H, Noguchi R, Kitada M, et al. Branched-chain amino acid suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats. J Gastroenterol. 2009;44:483–91.
    • (2009) J Gastroenterol , vol.44 , pp. 483-491
    • Yoshiji, H.1    Noguchi, R.2    Kitada, M.3
  • 38
    • 33646021275 scopus 로고    scopus 로고
    • Mild hepatic steatosis is not a major risk factor for hepatectomy and regenerative power is not impaired
    • PID: 16627060
    • Cho JY, Suh KS, Kwon CH, et al. Mild hepatic steatosis is not a major risk factor for hepatectomy and regenerative power is not impaired. Surgery. 2006;139:508–15.
    • (2006) Surgery , vol.139 , pp. 508-515
    • Cho, J.Y.1    Suh, K.S.2    Kwon, C.H.3
  • 39
    • 79953313457 scopus 로고    scopus 로고
    • The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice
    • COI: 1:CAS:528:DC%2BC3MXpsVGks7Y%3D, PID: 21372430
    • Arakawa M, Masaki T, Nishimura J, et al. The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice. Endocr J. 2011;58:161–70.
    • (2011) Endocr J , vol.58 , pp. 161-170
    • Arakawa, M.1    Masaki, T.2    Nishimura, J.3
  • 40
    • 0032992312 scopus 로고    scopus 로고
    • Utility of technetium-99m-labeled-galactosyl human serum albumin scintigraphy for estimating the hepatic functional reserve
    • COI: 1:STN:280:DyaK1MzgtVWntw%3D%3D, PID: 10372930
    • Fujioka H, Kawashita Y, Kamohara Y, et al. Utility of technetium-99m-labeled-galactosyl human serum albumin scintigraphy for estimating the hepatic functional reserve. J Clin Gastroenterol. 1999;28:329–33.
    • (1999) J Clin Gastroenterol , vol.28 , pp. 329-333
    • Fujioka, H.1    Kawashita, Y.2    Kamohara, Y.3
  • 41
    • 48549092299 scopus 로고    scopus 로고
    • Preoperative evaluation of hepatic functional reserve by converted ICGR15 calculated from Tc-GSA scintigraphy
    • PID: 18522682
    • Kawamura H, Kamiyama T, Nakagawa T, et al. Preoperative evaluation of hepatic functional reserve by converted ICGR15 calculated from Tc-GSA scintigraphy. J Gastroenterol Hepatol. 2008;23:1235–41.
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 1235-1241
    • Kawamura, H.1    Kamiyama, T.2    Nakagawa, T.3
  • 42
    • 83055174653 scopus 로고    scopus 로고
    • Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells
    • COI: 1:CAS:528:DC%2BC38XhtV2nsL0%3D
    • Ninomiya S, Shimizu M, Imai K, et al. Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells. Cancer Prev Res. 2011;4:2092–100.
    • (2011) Cancer Prev Res. , vol.4 , pp. 2092-2100
    • Ninomiya, S.1    Shimizu, M.2    Imai, K.3


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