Significance of branched chain amino acids as possible stimulators of hepatocyte growth factor

Biochemical and Biophysical Research Communications

Volumn 313, Issue 2, 2004, Pages 411-416

  Tomiya, Tomoaki ^a   Omata, Masao ^a   Fujiwara, Kenji ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

BCAA; HGF; Leucine

Indexed keywords

BRANCHED CHAIN AMINO ACID; INITIATION FACTOR 4E; ISOLEUCINE; LEUCINE; PROTEIN P53; S6 KINASE; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; VALINE;

ANGIOGENESIS; APOPTOSIS; CELL METABOLISM; CELL PROLIFERATION; CONFERENCE PAPER; DNA SYNTHESIS; DRUG ACTIVITY; GENE EXPRESSION; HEART INJURY; HEMATOPOIETIC CELL; HUMAN; KIDNEY FIBROSIS; KIDNEY INJURY; LIVER CELL; LIVER INJURY; LIVER REGENERATION; LUNG INJURY; LYMPHOID CELL; MITOGENESIS; MORPHOGENESIS; MUSCLE CELL; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; STELLATE CELL;

EID: 0346996345     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.07.017     Document Type: Conference Paper

References (57)

1. Crawford D.H., Shepherd R.W., Halliday J.W., Cooksley G.W., Golding S.D., Cheng W.S., Powell L.W. Body composition in nonalcoholic cirrhosis: the effect of disease etiology and severity on nutritional compartments. Gastroenterology. 106:1994;1611-1617.
2. Nielsen K., Kondrup J., Martinsen C., Shilling B., Wikman B. Nutritional assessment and adequacy of dietary intake in hospitalized patients with alcoholic cirrhosis. Br. J. Nutr. 69:1993;665-679.
3. ESPEN Consensus Group, M. Plauth, M. Merli, J. Kondrup, A. Weimann, P. Ferenci, M.J. Muller. ESPEN guidelines for nutrition in liver disease and transplantation. Clin. Nutr. 16 (1997) 43-55.
4. Ichihara A. BCA, HGF, and proteasomes. Biochem. Biophys. Res. Commun. 266:1999;647-651.
5. Cooper A.J.L. Role of the liver in amino acid metabolism. Zakim T., Boyer T.D. Hepatology; A Text Book of Liver Disease. 1996;563-601 W.B. Saunders, Philadelphia.
6. Marchesini G., Bianchi G., Rossi B., Brizi M., Melchionda N. Nutritional treatment with branched-chain amino acids in advanced liver cirrhosis. J. Gastroenterol. 35:2000;7-12.
7. Yamauchi M., Takeda K., Sakamoto K., Ohata M., Toda G. Effect of oral branched chain amino acid supplementation in the late evening on the nutritional state of patients with liver cirrhosis. Hepatol. Res. 21:2001;199-204.
8. Fabbri A., Magrini N., Bianchi G., Zoli M., Marchesini G. Overview of randomized clinical trials of oral branched-chain amino acid treatment in chronic hepatic encephalopathy. J. Parenter. Enteral. Nutr. 20:1996;159-164.
9. Marchesini G., Bianchi G., Merli M., Amodio P., Panella C., Loguercio C., Fanelli F.R., Abbiati R. Italian BCAA Study Group. Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial. Gastroenterology. 124:2003;1792-1801.
10. Hutson S.M., Harris R.A. Symposium: leucine as a nutritional signal: introduction. J. Nutr. 131:2001;839-840.
11. Gautsch T.A., Anthony J.C., Kimball S.R., Paul G.L., Layman D.K., Jefferson L.S. Availability of eIF4E regulates skeletal muscle protein synthesis during recovery from exercise. Am. J. Physiol. 274:1998;C406-C414.
12. Yoshizawa F., Kimball S.R., Jefferson L.S. Modulation of translation initiation in rat skeletal muscle and liver in response to food intake. Biochem. Biophys. Res. Commun. 240:1997;825-831.
13. Harris R.A., Kobayashi R., Murakami T., Shimomura Y. Regulation of branched-chain α-keto acid dehydrogenase kinase expression in rat liver. J. Nutr. 131:2001;841S-845S.
14. Flakoll P.J., Wentzel L.S., Rice D.E., Hill J.O., Abumrad N.N. Short-term regulation of insulin-mediated glucose utilization in four-day fasted human volunteers: role of amino acid availability. Diabetologia. 35:1992;357-366.
15. McDowell H.E., Christie G.R., Stenhouse G., Hundal H.S. Leucine activates system A amino acid transport in L6 rat skeletal muscle cells. Am. J. Physiol. 269:1995;C1287-C1294.
16. May M.E., Buse M.G. Effects of branched-chain amino acids on protein turnover. Diabetes Metab. Rev. 5:1989;227-245.
17. Louard R.J., Barrett E.J., Gelfand R.A. Overnight branched-chain amino acid infusion causes sustained suppression of muscle proteolysis. Metabolism. 44:1995;424-429.
18. Laine R.O., Hutson R.G., Kilberg M.S. Eukaryotic gene expression: metabolite control by amino acids. Progr. Nucleic Acid Res. Mol. Biol. 53:1996;219-248.
19. Peyrollier K., Hajduch E., Blair A.S., Hyde R., Hundal H.S. L-Leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of System A amino acid transport. Biochem. J. 350:2000;361-368.
20. Shigemitsu K., Tsujishita Y., Miyake H., Hidayat S., Tanaka N., Hara K., Yonezawa K. Structural requirement of leucine for activation of p70 S6 kinase. FEBS Lett. 447:1999;303-306.
21. Xu G., Kwon G., Marshall C.A., Lin T.A., Lawrence J.C. Jr., McDaniel M.L. Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling. J. Biol. Chem. 273:1998;28178-28184.
22. Anthony J.C., Lang C.H., Crozier S.J., Anthony T.G., MacLean D.A., Kimball S.R., Jefferson L.S. Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine. Am. J. Physiol. Endocrinol. Metab. 282:2002;E1092-E1101.
23. Gitlin N. Hepatic encephalopathy. Zakim T., Boyer T.D. Hepatology; A text book of liver disease. 1996;605-617 W.B. Saunders, Philadelphia.
24. Michalopoulos G.K., DeFrances M.C. Liver regeneration. Science. 276:1997;60-66.
25. Tsubouchi H. Hepatocyte growth factor for liver disease. Hepatology. 30:1999;333-334.
26. Zarnegar R., Michalopoulos G.K. The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J. Cell Biol. 129:1995;1177-1180.
27. Fausto N. Liver regeneration. J. Hepatol. 32:2000;S-19.
28. Matsumoto K., Nakamura T. Emerging multipotent aspects of hepatocyte growth factor. J. Biochem. 119:1996;591-600.
29. Funakoshi H., Nakamura T. Hepatocyte growth factor: from diagnosis to clinical applications. Clin. Chim. Acta. 327:2003;1-23.
30. Maina F., Klein R. Hepatocyte growth factor, a versatile signal for developing neurons. Nat. Neurosci. 2:1999;213-217.
31. Bussolino F., Di Renzo M.F., Ziche M., Bocchietto E., Olivero M., Naldini L., Gaudino G., Tamagnone L., Coffer A., Comoglio P.M. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J. Cell Biol. 119:1992;629-641.
32. Ware L.B., Matthay M.A. Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am. J. Physiol. 282:2002;L924-L940.
33. Fujiwara K., Nagoshi S., Ohno A., Hirata K., Ohta Y., Mochida S., Tomiya T., Higashio K., Kurokawa K. Stimulation of liver growth by exogenous human hepatocyte growth factor in normal and partially hepatectomized rats. Hepatology. 18:1993;1443-1449.
34. Yamaoka M., Hirata K., Ogata I., Tomiya T., Nagoshi S., Mochida S., Fujiwara K. Enhancement of albumin production by hepatocyte growth factor in rat hepatocytes: distinction in mode of action from stimulation of DNA synthesis. Liver. 18:1998;52-59.
35. Ueki T., Kaneda Y., Tsutsui H., Nakanishi K., Sawa Y., Morishita R., Matsumoto K., Nakamura T., Takahashi H., Okamoto E., Fujimoto J. Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat. Med. 5:1999;226-230.
36. Ishiki Y., Ohnishi H., Muto Y., Matsumoto K., Nakamura T. Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effect in vivo. Hepatology. 16:1992;1227-1235.
37. Tomiya T., Nagoshi S., Fujiwara K. Significance of serum human hepatocyte growth factor levels in patients with hepatic failure. Hepatology. 15:1992;1-4.
38. Tomiya T., Tani M., Yamada S., Hayashi S., Umeda N., Fujiwara K. Serum hepatocyte growth factor levels in hepatectomized and non-hepatectomized surgical patients. Gastroenterology. 103:1992;1621-1624.
39. Tomiya T., Fujiwara K. Serum levels of transforming growth factor α in patients after partial hepatectomy as determined by an enzyme linked immunosorbent assay. Hepatology. 18:1993;304-308.
40. Tomiya T., Fujiwara K. Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor α levels. Hepatology. 23:1996;253-257.
41. Tomiya T., Hayashi S., Yanase M., Umeda N., Tani M., Yamada S., Masaki N., Ogata I., Fujiwara K. Serum transforming growth factor α level can be a parameter for liver regeneration after partial hepatectomy in patients with liver cancer. Semin. Oncol. 24:1997;14-17.
42. Tomiya T., Ogata I., Fujiwara K. Transforming growth factor alpha levels in liver and blood correlate better than hepatocyte growth factor with hepatocyte proliferation during liver regeneration. Am. J. Pathol. 153:1998;955-961.
43. Tomiya T., Ogata I., Yamaoka M., Yanase M., Inoue Y., Fujiwara K. The mitogenic activity of hepatocyte growth factor on rat hepatocytes is dependent upon endogenous transforming growth factor α Am. J. Pathol. 157:2000;1693-1701.
44. Inoue Y., Tomiya T., Yanase M., Arai M., Ikeda H., Tejima K., Ogata I., Kimura S., Omata M., Fujiwara K. P53 may positively regulate hepatocyte proliferation in rats. Hepatology. 36:2002;336-344.
45. Scheving L.A., Stevenson M.C., Taylormoore J.M., Traxler P., Russell W.E. Integral role of the EGF receptor in HGF-mediated hepatocyte proliferation. Biochem. Biophys. Res. Commun. 290:2002;197-203.
46. Maeshima A., Zhang Y.Q., Furukawa M., Naruse T., Kojima I. Hepatocyte growth factor induces branching tubulogenesis in MDCK cells by modulating the activin-follistatin system. Kidney Int. 58:2000;1511-1522.
47. Gohda E., Kataoka H., Tsubouchi H., Daikilara Y., Yamamoto I. Phorbol ester-induced secretion of human hepatocyte growth factor by human skin fibroblasts and its inhibition by dexamethasone. FEBS Lett. 301:1992;107-110.
48. Tamura M., Arakaki N., Tsubouchi H., Takada H., Daikuhara Y. Enhancement of human hepatocyte growth factor production by interleukin-1 alpha and -1 beta and tumor necrosis factor-alpha by fibroblasts in culture. J. Biol. Chem. 268:1993;8140-8145.
49. Inaba M., Koyama H., Hino M., Okuno S., Terada M., Nishizawa Y., Nishino T., Morii H. Regulation of release of hepatocyte growth factor from human promyelocytic leukemia cells, HL-60, by 1,25-dihydroxyvitamin D3, 12-O-tetradecanoylphorbol 13-acetate, and dibutyryl cyclic adenosine monophosphate. Blood. 82:1993;53-59.
50. Liu Y., Michalopoulos G.K., Zarnegar R. Structural and functional characterization of the mouse hepatocyte growth factor gene promoter. J. Biol. Chem. 269:1994;4152-4160.
51. Gohda E., Matsunaga T., Kataoka H., Takebe T., Yamamoto I. Induction of hepatocyte growth factor in human skin fibroblasts by epidermal growth factor, platelet-derived growth factor and fibroblast growth factor. Cytokine. 6:1994;633-640.
52. Broten J., Michalopoulos G., Petersen B., Cruise J. Adrenergic stimulation of hepatocyte growth factor expression. Biochem. Biophys. Res. Commun. 262:1999;76-79.
53. Matsumoto K., Tajima H., Hamanoue M., Kohno S., Kinoshita T., Nakamura T. Identification and characterization of "injurin," an inducer of expression of the gene for hepatocyte growth factor. Proc. Natl. Acad. Sci. USA. 89:1992;3800-3804.
54. Haug C., Schmid-Kotsas A., Zorn U., Bachem M.G., Schuett S., Gruenert A., Rozdzinski E. Hepatocyte growth factor is upregulated by low-density lipoproteins and inhibits endothelin-1 release. Am. J. Physiol. 279:2000;H2865-H2871.
55. Tomiya T., Inoue Y., Yanase M., Arai M., Ikeda H., Tejima K., Nagashima K., Nishikawa T., Fujiwara K. Leucine stimulates the secretion of hepatocyte growth factor by hepatic stellate cells. Biochem. Biophys. Res. Commun. 297:2002;1108-1111.
56. Greenwel P., Schwartz M., Rosas M., Peyrol S., Grimaud J.A., Rojkind M. Characterization of fat-storing cell lines derived from normal and CCl4-cirrhotic livers. Differences in the production of interleukin-6. Lab Invest. 65:1991;644-653.
57. Greenwel P., Rubin J., Schwartz M., Hertzberg E.L., Rojkind M. Liver fat-storing cell clones obtained from a CCl4-cirrhotic rat are heterogeneous with regard to proliferation, expression of extracellular matrix components, interleukin-6, and connexin 43. Lab. Invest. 69:1993;210-216.