Branched-chain amino acid-enriched nutrients improve nutritional and metabolic abnormalities in the early post-transplant period after living donor liver transplantation

Journal of Hepato-Biliary-Pancreatic Sciences

Volumn 19, Issue 4, 2012, Pages 438-448

  Yoshida, Ryuichi ^a   Yagi, Takahito ^a   Sadamori, Hiroshi ^a   Matsuda, Hiroaki ^a   Shinoura, Susumu ^a   Umeda, Yuzo ^a   Sato, Daisuke ^a   Utsumi, Masashi ^a   Nagasaka, Takeshi ^a   Okazaki, Nami ^a   Date, Ai ^a   Noguchi, Ayako ^a   Tanaka, Akemi ^a   Hasegawa, Yuko ^a   Sakamoto, Yachiyo ^a   Fujiwara, Toshiyoshi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Branched chain amino acid enriched nutrients; Energy metabolism; Living donor liver transplantation; Non protein respiratory quotient; Perioperative nutrition

Indexed keywords

BRANCHED CHAIN AMINO ACID; RETINOL BINDING PROTEIN; TYROSINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIET THERAPY; ENTERIC FEEDING; FEMALE; HUMAN; LIVER TRANSPLANTATION; LIVING DONOR LIVER TRANSPLANTATION; MALE; METABOLIC DISORDER; NUTRIENT; NUTRITIONAL DISORDER; PILOT STUDY; POSTOPERATIVE CARE; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY QUOTIENT; TREATMENT OUTCOME;

ADULT; AMINO ACIDS, BRANCHED-CHAIN; CALORIMETRY, INDIRECT; DIETARY SUPPLEMENTS; ENERGY METABOLISM; ENTERAL NUTRITION; FEMALE; HUMANS; LIVER DISEASES; LIVER REGENERATION; LIVER TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; NUTRITIONAL STATUS; PILOT PROJECTS; POSTOPERATIVE PERIOD; PROSPECTIVE STUDIES;

EID: 84865503158     PISSN: 18686974     EISSN: 18686982     Source Type: Journal    
DOI: 10.1007/s00534-011-0459-5     Document Type: Article

References (43)

1. Lautz HU, Selverg O, Körber J, Bürger M, Mü ller MJ. Proteincalorie malnutrition in liver cirrhosis. Clin Investig. 1992;70: 478-86.
2. Müller MJ, Lauts HU, Plogmann B, Bürger M, Körber J, Schmidt FW. Energy expenditure and substrate oxidation in patients with cirrhosis: the impact of cause, clinical staging and nutritional state. Hepatology. 1992;15:782-94.
3. Crawford DH, Shepherd RW, Halliday JW, Cooksley GW, Golding SD, Cheng WS, et al. Body composition in nonalcoholic cirrhosis: the effect of disease etiology and severity on nutritional compartments. Gastroenterology. 1994;106:1611-7.
4. Italian Multicentre Cooperative Project on Nutrition in Liver Cirrhosis. Nutritional status in cirrhosis. J Hepatol. 1994;21:317-335.
5. Nielsen K, Kondrup J, Martinsen L, Stilling B, Wikman B. Nutritional assessment and adequacy of dietary intake in hospitalized patients with alcoholic cirrhosis. Br J Nutr. 1993;69(3): 665-79.
6. Merli M, Romiti A, Riggio O, Capocaccia L. Optimal nutritional indexes in chronic liver disease. J Parenter Enter Nutr. 1987;11(5 Suppl):130S-4S.
7. Porayko MK, DiCecco S, O'Keefe SJ. Impact of malnutrition, its therapy on liver transplantation. SeminLiver Dis. 1991;11(4):305-14.
8. Moriwaki H, Shiraki M, Fukushima H, Shimizu M, Iwasa J, Naiki T, et al. Long-term outcome of branched-chain amino acid treatment in patients with liver cirrhosis. Hepatol Res. 2008;38:S102-6.
9. Nakaya Y, Okita K, Suzuki K, Moriwaki H, Kato A, Miwa Y, et al. BCAA-enriched snack improves nutritional state of cirrhosis. Nutrition. 2007;23:113-20.
10. The San-in Group of Liver Surgery. Long-term oral administration of branched chain amino acids after curative resection of hepatocellular carcinoma: a prospective randomized trial. Br J Surg. 1997;84(11):1525-1531.
11. Meng WC, Leung KL, Ho RL, Leung TW, Lau WY. Prospective randomized control study on the effect of branched-chain amino acids in patients with liver resection for hepatocellular carcinoma. Aust N Z J Surg. 1999;69(11):811-5.
12. Poon RT, Yu WC, Fan ST, Wong J. Long-term oral branched chain amino acids in patients undergoing chemoembolization for hepatocellular carcinoma: a randomized trial. Aliment Pharmacol Ther. 2004;19(7):779-88.
13. Muto Y, Sato S, Watanabe A, Moriwaki H, Suzuki K, Kato A, Long-Term Survival Study Group, et al. Effects of oral branchedchain amino acid granules on event-free survival in patients with liver cirrhosis. Clin Gastroenterol Hepatol. 2005;3(7):705-13.
14. Takeshita S, Ichikawa T, Nakao K, Miyaaki H, Shibata H, Matsuzaki T, et al. A snack enriched with oral branched-chain amino acids prevents a fall in albumin in patients with liver cirrhosis undergoing chemoembolization for hepatocellular carcinoma. Nutr Res. 2009;29(2):89-93.
15. Ishikawa T, Michitaka I, Kamimura H, Higuchi K, Kubota T, Seki K, et al. Oral branched-chain amino acids administration improves impaired liver dysfunction after radiofrequency ablation therapy for hepatocellular carcinoma. Hepatogastroenterology. 2009;56(94-95):1491-5.
16. Kuroda H, Ushio A, Miyamoto Y, Sawara K, Oikawa K, Kasai K, et al. Effects of branched-chain amino acid-enriched nutrient for patients with hepatocellular carcinoma following radiofrequency ablation: a one-year prospective trial. J Gastroenterol Hepatol. 2010;25(9):1550-5.
17. Uemoto S. Liver transplantation. Nippon Rinsho. 2010;68(12):2277-2280 (in Japanese with English abstract).
18. Iida T, Kaido T, Yagi S, Yoshizawa A, Hata K, Mizumoto M, et al. Posttransplant bacteremia in adult living donor liver transplant recipients. Liver Transplant. 2010;16(12):1379-85.
19. Hasse JM. Nutritional implications of liver transplantation. Henry Ford Hosp Med J. 1990;38:235-40.
20. Campos AC, Matias JE, Coelho JC. Nutritional aspects of liver transplantation. Curr Opin Clin Nutr Metab Care. 2002;5(3): 297-307 (Review).
21. Sanchez AJ, Aranda-Michel J. Nutrition for the liver transplant patient. Liver Transplant. 2006;12:1310-6.
22. Selberg O, Böttcher J, Tusch G, Pichlmayr R, Henkel E,Mü ller MJ. Identification of high- and low-risk patients before liver transplantation: a prospective cohort study of nutritional and metabolic parameters in 150 patients. Hepatology. 1997;25(3):652-7.
23. Plauth M, Cabré E, Riggio O, Assis-Camilo M, Pirlich M, Kondrup J, et al. ESPEN guidelines on enteral nutrition: liver disease. Clin Nutr. 2006;25(2):285-94.
24. Okita M, Watanabe A, Nagashima H. Nutritional treatment of liver cirrhosis by branched-chain amino acid-enriched nutrient mixture. J Nutr Sci Vitaminol. 1985;31:291-303.
25. Fischer JE, Rosen HM, Ebeid AM, James JH, Keane JM, Soeters PB. The effect of normalization of plasma amino acids on hepatic encephalopathy in man. Surgery. 1976;80(1):77-91.
26. Marshall WJ. Nutritional assessment: its role in the provision of nutritional support. J Clin Pathol. 2008;61(10):1083-8.
27. Kaido T, Egawa H, Tsuji H, Ashihara E, Maekawa T, Uemoto S. In-hospital mortality in adult recipients of living donor liver transplantation: experience of 576 consecutive cases at a single center. Liver Transplant. 2009;15(11):1420-5.
28. Kajiwara K, Okuno M, Kobayashi T, Honma N, Maki T, Kato M, et al. Oral supplementation with branched chain amino acids improves survival rate of rats with carbon tetrachloride-induced liver cirrhosis. Dig Dis Sci. 1998;43:1572-9.
29. Yoshida T, Muto Y, Moriwaki H, Yamato M. Effect of long-term oral supplementation with branched chain amino acid granules on the prognosis of liver cirrhosis. J Gastroenterol. 1989;24:692-8.
30. Hasse JM, Blue LS, Liepa GU, Goldstein RM, Jennings LW, Mor E, et al. Early enteral nutrition support in patients undergoing liver transplantation. J Parenter Enter Nutr. 1995;19(6):437-43.
31. Ingenbleek Y, De Visscher M, De Nayer P. Measurement of prealbumin as index of protein-calorie malnutrition. Lancet. 1972;2(7768):106-9.
32. Beck FK, Rosenthal TC. Prealbumin: a marker for nutritional evaluation. Am Fam Physician. 2002;65(8):1575-8.
33. Ingenbleek Y, Van Den Schrieck HG, De Nayer P, De Visscher M. The role of retinol-binding protein in protein-calorie malnutrition. Metabolism. 1975;24(5):633-41.
34. Holecek M. Nutritional modulation of liver regeneration by carbohydrates, lipids, and amino acids: a review. Nutrition. 1999;15(10):784-8.
35. Ijichi C, Matsumura T, Tsuji T, Eto Y. Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system. Biochem Biophys Res Commun. 2003;303(1):59-64.
36. Nishitani S, Takehana K. Pharmacological activities of branchedchain amino acids: augmentation of albumin synthesis in liver and improvement of glucose metabolism in skeletal muscle. Hepatol Res. 2004;30S:19-24.
37. Matsumura T, Morinaga Y, Fujitani S, Takehana K, Nishitani S, Sonaka I. Oral administration of branched-chain amino acids activates the mTOR signal in cirrhotic rat liver. Hepatol Res. 2005;33(1):27-32.
38. Greco AV, Mingrone G, Benedetti G, Capristo E, Tataranni PA, Gasbarrini G. Daily energy and substrate metabolism in patients with cirrhosis. Hepatology. 1998;27(2):346-50.
39. Tajika M, Kato M, Mohri H, Miwa Y, Kato T, Ohnishi H, et al. Prognostic value of energy metabolism in patients with viral liver cirrhosis. Nutrition. 2002;18(3):229-34.
40. Plevak DJ, DiCecco SR, Wiesner RH, Porayko MK, Wahlstrom HE, Janzow DJ, et al. Nutritional support for liver transplantation: identifying caloric and protein requirements. Mayo Clin Proc. 1994;69(3):225-30.
41. Calder PC. Branched-chain amino acids and immunity. J Nutr. 2006;136(1 Suppl):288S-93S.
42. Petro TM, Bhattacharjee JK. Effect of dietary essential amino acid limitations upon the susceptibility to Salmonella typhimurium and the effect upon humoral and cellular immune responses in mice. Infect Immun. 1981;32(1):251-9.
43. Aschkenasy A. Prevention of the immunodepressive effects of excess dietary leucine by isoleucine and valine in the rat. J Nutr. 1979;109(7):1214-22.