Fused 99m-Tc-GSA SPECT/CT imaging for the preoperative evaluation of postoperative liver function: Can the liver uptake index predict postoperative hepatic functional reserve?

Japanese Journal of Radiology

Volumn 30, Issue 3, 2012, Pages 255-262

  Yoshida, Morikatsu ^a   Tashiro, Kuniyuki ^b   Baba, Hideo ^a,c   Shiraishi, Shinya ^a   Tomiguchi, Seiji ^a,c   Yamashita, Yasuyuki ^a   Sakaguchi, Fumi ^a   Okabe, Hirohisa ^a,c   Utsunomiya, Daisuke ^a   Beppu, Toru ^a,c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO CITY HOSPITAL   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

Author keywords

99mTc GSA SPECT; Computed tomography; Fusion imaging; Liver function; Liver resection

Indexed keywords

BILIRUBIN; DIETHYLENE TRIAMINE PENTAACETATE GALACTOSYL HUMAN SERUM ALBUMIN TC 99M; GALACTOSE; PENTETIC ACID; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BILIRUBIN BLOOD LEVEL; BODY SURFACE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; DISEASE SEVERITY; FEMALE; HUMAN; LIVER DYSFUNCTION; LIVER FUNCTION TEST; LIVER METABOLISM; LIVER RESECTION; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTHROMBIN TIME; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

AGED; FEMALE; HEPATECTOMY; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LIVER DISEASES; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; POSTOPERATIVE PERIOD; PREDICTIVE VALUE OF TESTS; PREOPERATIVE PERIOD; RADIOPHARMACEUTICALS; RETROSPECTIVE STUDIES; ROC CURVE; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M AGGREGATED ALBUMIN; TECHNETIUM TC 99M PENTETATE;

EID: 84863215754     PISSN: 18671071     EISSN: 1867108X     Source Type: Journal    
DOI: 10.1007/s11604-011-0041-8     Document Type: Article

References (35)

1. Hwang EH, Taki J, Shuke N, Nakajima K, Kinuya S, Konishi S, et al. Preoperative assessment of residual hepatic functional reserve using 99mTc-DTPA-galactosyl-human serum albumin dynamic SPECT. J Nucl Med. 1999;40(10):1644-51. (Pubitemid 29471154)
2. Kokudo N, Vera DR, Koizumi M, Seki M, Sato T, Stadalnik RC, et al. Recovery of hepatic asialoglycoprotein receptors after major hepatic resection. J Nucl Med. 1999;40(1):137-41. (Pubitemid 29044184)
3. Mitsumori A, Nagaya I, Kimoto S, Akaki S, Togami I, Takeda Y, et al. Preoperative evaluation of hepatic functional reserve following hepatectomy by technetium-99m galactosyl human serum albumin liver scintigraphy and computed tomography. Eur J Nucl Med. 1998;25(10):1377-82. (Pubitemid 28464111)
4. Stadalnik RC, Vera DR, Woodle ES, Trudeau WL, Porter BA, Ward RE, et al. Technetium-99m NGA functional hepatic imaging: preliminary clinical experience. J Nucl Med. 1985; 26(11):1233-42. (Pubitemid 16020936)
5. Kubota K, Makuuchi M, Kusaka K, Kobayashi T, Miki K, Hasegawa K, et al. Measurement of liver volume and hepatic functional reserve as a guide to decision-making in resectional surgery for hepatic tumors. Hepatology. 1997;26(5):1176-81. (Pubitemid 27509300)
6. Kwon AH, Matsui Y, Kaibori M, Ha-Kawa SK. Preoperative regional maximal removal rate of technetium-99m-galactosyl human serum albumin (GSA-Rmax) is useful for judging the safety of hepatic resection. Surgery. 2006;140(3):379-86.
7. Madoff DC, Hicks ME, Vauthey JN, Charnsangavej C, Morello FA Jr, Ahrar K, et al. Transhepatic portal vein embolization: anatomy, indications, and technical considerations. Radiographics. 2002;22(5):1063-76.
8. Matsuzaki S, Onda M, Tajiri T, Kim DY. Hepatic lobar differences in progression of chronic liver disease: correlation of asialoglycoprotein scintigraphy and hepatic functional reserve. Hepatology. 1997;25(4):828-32. (Pubitemid 27157121)
9. Kudo M, Todo A, Ikekubo K, Hino M. Receptor index via hepatic asialoglycoprotein receptor imaging: correlation with chronic hepatocellular damage. Am J Gastroenterol. 1992;87(7):865-70.
10. Kwon AH, Ha-Kawa SK, Uetsuji S, Kamiyama Y, Tanaka Y. Use of technetium 99m diethylenetriamine-pentaacetic acid-galactosyl- human serum albumin liver scintigraphy in the evaluation of preoperative and postoperative hepatic functional reserve for hepatectomy. Surgery. 1995;117(4):429-34.
11. Vera DR, Stadalnik RC, Trudeau WL, Scheibe PO, Krohn KA. Measurement of receptor concentration and forward-binding rate constant via radiopharmacokinetic modeling of technetium-99mgalactosyl- neoglycoalbumin. J Nucl Med. 1991;32(6):1169-76.
12. Ha-Kawa SK, Tanaka Y.Aquantitative model of technetium-99m- DTPA-galactosyl-HSA for the assessment of hepatic blood flow and hepatic binding receptor. J Nucl Med. 1991;32(12):2233-40.
13. Miki K, Kubota K, Kokudo N, Inoue Y, Bandai Y, Makuuchi M. Asialoglycoprotein receptor and hepatic blood flow using technetium- 99m-DTPA-galactosyl human serum albumin. J Nucl Med. 1997;38(11):1798-807. (Pubitemid 27495534)
14. Shuke N, Okizaki A, Kino S, Sato J, Ishikawa Y, Zhao C, et al. Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT. J Nucl Med. 2003;44(3):475-82. (Pubitemid 39586027)
15. Kaibori M, Ha-Kawa SK, Ishizaki M, Matsui K, Saito T, Kwon AH, et al. HA/GSA-Rmax ratio as a predictor of postoperative liver failure. World J Surg. 2008;32(11):2410-8.
16. Beppu T, Hayashi H, Okabe H, Masuda T, Mima K, Otao R, et al. Liver functional volumetry for portal vein embolization using a newly developed (99m)Tc-galactosyl human serum albumin scintigraphy SPECT-computed tomography fusion system. J Gastroenterol. 2011;46(7):938-43
17. Slankamenac K, Breitenstein S, Held U, Beck-Schimmer B, Puhan MA, Clavien PA. Development and validation of a prediction score for postoperative acute renal failure following liver resection. Ann Surg Clin Trial Valid Stud. 2009;250(5):720-8.
18. Sugahara K, Togashi H, Takahashi K, Onodera Y, Sanjo M, Misawa K, et al. Separate analysis of asialoglycoprotein receptors in the right and left hepatic lobes using Tc-GSA SPECT. Hepatology. 2003;38(6):1401-9. (Pubitemid 37466966)
19. Balzan S, Belghiti J, Farges O, Ogata S, Sauvanet A, Delefosse D, et al. The ''50-50 criteria'' on postoperative day 5: an accurate predictor of liver failure and death after hepatectomy. Ann Surg. 2005;242(6):824-8. discussion 8-9.
20. Paugam-Burtz C, Janny S, Delefosse D, Dahmani S, Dondero F, Mantz J, et al. Prospective validation of the ''fifty-fifty'' criteria as an early and accurate predictor of death after liver resection in intensive care unit patients. Ann Surg. 2009;249(1):124-8.
21. Jarnagin WR, Gonen M, Fong Y, DeMatteo RP, Ben-Porat L, Little S, et al. Improvement in perioperative outcome after hepatic resection: analysis of 1,803 consecutive cases over the past decade. Ann Surg. 2002;236(4):397-406, discussion 7.
22. Shirabe K, Shimada M, Gion T, Hasegawa H, Takenaka K, Utsunomiya T, et al. Postoperative liver failure after major hepatic resection for hepatocellular carcinoma in the modern era with special reference to remnant liver volume. J Am Coll Surg. 1999;188(3):304-9. (Pubitemid 29113766)
23. Ashwell G, Morell AG. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. Adv Enzymol Relat Areas Mol Biol. 1974;41:99-128.
24. Marshall JS, Green AM, Pensky J, Williams S, Zinn A, Carlson DM. Measurement of circulating desialylated glycoproteins and correlation with hepatocellular damage. J Clin Invest. 1974;54(3): 555-62.
25. Sawamura T, Kawasato S, Shiozaki Y, Sameshima Y, Nakada H, Tashiro Y. Decrease of a hepatic binding protein specific for asialoglycoproteins with accumulation of serum asialoglycoproteins in galactosamine-treated rats. Gastroenterology. 1981;81(3): 527-33. (Pubitemid 11061553)
26. Kwon AH, Ha-Kawa SK, Uetsuji S, Inoue T, Matsui Y, Kamiyama Y. Preoperative determination of the surgical procedure for hepatectomy using technetium-99m-galactosyl human serum albumin (99mTc-GSA) liver scintigraphy. Hepatology. 1997; 25(2):426-9. (Pubitemid 27069066)
27. Sasaki N, Shiomi S, Iwata Y, Nishiguchi S, Kuroki T, Kawabe J, et al. Clinical usefulness of scintigraphy with 99mTc-galactosylhuman serum albumin for prognosis of cirrhosis of the liver. J Nucl Med. 1999;40(10):1652-6. (Pubitemid 29471155)
28. Kira T, Tomiguchi S, Takahashi M, Yoshimatsu S, Sagara K, Kurano R. Correlation of 99mTc-GSA hepatic scintigraphy with liver biopsies in patients with chronic active hepatitis type C. Radiat Med. 1999;17(2):125-30. (Pubitemid 29252202)
29. Seo Y, Mari C, Hasegawa BH. Technological development and advances in single-photon emission computed tomography/computed tomography. Semin Nucl Med. 2008;38(3):177-98. (Pubitemid 351466914)
30. Yumoto Y, Yagi T, Sato S, Nouso K, Kobayashi Y, Ohmoto M, et al. Preoperative estimation of remnant hepatic function using fusion images obtained by (99m)Tc-labelled galactosyl-human serum albumin liver scintigraphy and computed tomography. Br J Surg. 2010;97(6):934-44.
31. Bachellier P, Rosso E, Pessaux P, Oussoultzoglou E, Nobili C, Panaro F, et al. Risk factors for liver failure and mortality after hepatectomy associated with portal vein resection. Ann Surg. 2011;253(1):173-9.
32. Mathur AK, Ghaferi AA, Osborne NH, Pawlik TM, Campbell DA, Englesbe MJ, et al. Body mass index and adverse perioperative outcomes following hepatic resection. J Gastrointest Surg. 2010;14(8):1285-91.
33. Lynch RJ, Ranney DN, Shijie C, Lee DS, Samala N, Englesbe MJ. Obesity, surgical site infection, and outcome following renal transplantation. Ann Surg. 2009;250(6):1014-20.
34. Wei AC, Tung-Ping Poon R, Fan ST, Wong J. Risk factors for perioperative morbidity and mortality after extended hepatectomy for hepatocellular carcinoma. Br J Surg. 2003;90(1):33-41. (Pubitemid 37040968)
35. Takenaka K, Kanematsu T, Fukuzawa K, Sugimachi K. Can hepatic failure after surgery for hepatocellular carcinoma in cirrhotic patients be prevented? World J Surg. 1990;14(1):123-7. (Pubitemid 20091468)