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Volumn 172, Issue 23, 2015, Pages 5425-5429

Chinese innovation in cardiovascular drug discovery

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALDOSTERONE ANTAGONIST; BONE MORPHOGENETIC PROTEIN 4; CARDIOVASCULAR AGENT; EPITHELIAL SODIUM CHANNEL; G PROTEIN COUPLED RECEPTOR; HYDROGEN SULFIDE; INTERFERON REGULATORY FACTOR;

EID: 84949497298     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13363     Document Type: Review
Times cited : (4)

References (39)
  • 7
    • 84935031646 scopus 로고    scopus 로고
    • Class A1 scavenger receptors in cardiovascular diseases
    • Ben J, Zhu X, Zhang H, Chen Q, (2015). Class A1 scavenger receptors in cardiovascular diseases. Br J Pharmacol 172: 5435-5443. doi: 10.1111/bph.13105
    • (2015) Br J Pharmacol , vol.172 , pp. 5435-5443
    • Ben, J.1    Zhu, X.2    Zhang, H.3    Chen, Q.4
  • 8
    • 20044373069 scopus 로고    scopus 로고
    • Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension
    • Brunner H, Cockcroft JR, Deanfield J, Donald A, Ferrannini E, Halcox J, et al. (2005). Endothelial function and dysfunction. Part II: association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension. J Hypertens 23: 233-246.
    • (2005) J Hypertens , vol.23 , pp. 233-246
    • Brunner, H.1    Cockcroft, J.R.2    Deanfield, J.3    Donald, A.4    Ferrannini, E.5    Halcox, J.6
  • 9
    • 84949531083 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptors in cardiovascular diseases: Experimental benefits and clinical challenges
    • Cheang WS, Tian XY, Wong WT, Huang Y, (2015). The peroxisome proliferator-activated receptors in cardiovascular diseases: experimental benefits and clinical challenges. Br J Pharmacol 172: 5512-5522. doi: 10.1111/bph.13029
    • (2015) Br J Pharmacol , vol.172 , pp. 5512-5522
    • Cheang, W.S.1    Tian, X.Y.2    Wong, W.T.3    Huang, Y.4
  • 10
    • 84949539703 scopus 로고    scopus 로고
    • Regulator of G-protein signalling 5 protects against atherosclerosis in apolipoprotein E-deficient mice
    • Cheng WL, Wang PX, Wang T, Zhang Y, Du C, Li H, et al. (2015). Regulator of G-protein signalling 5 protects against atherosclerosis in apolipoprotein E-deficient mice. Br J Pharmacol 172: 5676-5689. doi: 10.1111/bph.12991
    • (2015) Br J Pharmacol , vol.172 , pp. 5676-5689
    • Cheng, W.L.1    Wang, P.X.2    Wang, T.3    Zhang, Y.4    Du, C.5    Li, H.6
  • 11
    • 84890560949 scopus 로고    scopus 로고
    • Mechanisms of aspirin resistance
    • Floyd CN, Ferro A, (2014). Mechanisms of aspirin resistance. Pharmacol Ther 141: 69-78.
    • (2014) Pharmacol Ther , vol.141 , pp. 69-78
    • Floyd, C.N.1    Ferro, A.2
  • 12
    • 0002537440 scopus 로고    scopus 로고
    • Cardiac hypertrophy: The good, the bad, and the ugly
    • Frey N, Olson EN, (2003). Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol 65: 45-79.
    • (2003) Annu Rev Physiol , vol.65 , pp. 45-79
    • Frey, N.1    Olson, E.N.2
  • 13
    • 84949522119 scopus 로고    scopus 로고
    • Cardiovascular research is thriving in China
    • Gao F, Sun RJ, Ji Y, Yang BF, (2015). Cardiovascular research is thriving in China. Br J Pharmacol 172: 5430-5434. doi: 10.1111/bph.12826
    • (2015) Br J Pharmacol , vol.172 , pp. 5430-5434
    • Gao, F.1    Sun, R.J.2    Ji, Y.3    Yang, B.F.4
  • 14
    • 84949529000 scopus 로고    scopus 로고
    • Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling
    • Gong Y, Lin M, Piao L, Li X, Yang F, Zhang J, et al. (2015). Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling. Br J Pharmacol 172: 5647-5660. doi: 10.1111/bph.12986
    • (2015) Br J Pharmacol , vol.172 , pp. 5647-5660
    • Gong, Y.1    Lin, M.2    Piao, L.3    Li, X.4    Yang, F.5    Zhang, J.6
  • 15
    • 84893644015 scopus 로고    scopus 로고
    • Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: A systematic review and meta-analysis
    • Gouya G, Arrich J, Wolzt M, Huber K, Verheugt FW, Gurbel PA, et al. (2014). Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis. Stroke 45: 492-503.
    • (2014) Stroke , vol.45 , pp. 492-503
    • Gouya, G.1    Arrich, J.2    Wolzt, M.3    Huber, K.4    Verheugt, F.W.5    Gurbel, P.A.6
  • 16
    • 84949535666 scopus 로고    scopus 로고
    • Novel strategies and underlying protective mechanisms of modulation of vagal activity in cardiovascular diseases
    • He X, Zhao M, Bi X, Sun L, Yu X, Zhao M, et al. (2015). Novel strategies and underlying protective mechanisms of modulation of vagal activity in cardiovascular diseases. Br J Pharmacol 172: 5489-5500. doi: 10.1111/bph.13010
    • (2015) Br J Pharmacol , vol.172 , pp. 5489-5500
    • He, X.1    Zhao, M.2    Bi, X.3    Sun, L.4    Yu, X.5    Zhao, M.6
  • 17
    • 84879202874 scopus 로고    scopus 로고
    • Forecasting the impact of heart failure in the United States: A policy statement from the American Heart Association
    • Heidenreich PA, Albert NM, Allen LA, Bluemke DA, Butler J, Fonarow GC, et al. (2013). Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association. Circ Heart Fail 6: 606-619.
    • (2013) Circ Heart Fail , vol.6 , pp. 606-619
    • Heidenreich, P.A.1    Albert, N.M.2    Allen, L.A.3    Bluemke, D.A.4    Butler, J.5    Fonarow, G.C.6
  • 18
    • 84866041941 scopus 로고    scopus 로고
    • The pathophysiology of heart failure
    • Kemp CD, Conte JV, (2012). The pathophysiology of heart failure. Cardiovasc Pathol 21: 365-371.
    • (2012) Cardiovasc Pathol , vol.21 , pp. 365-371
    • Kemp, C.D.1    Conte, J.V.2
  • 19
    • 84949534029 scopus 로고    scopus 로고
    • Activation of TRPV1 attenuates high salt-induced cardiac hypertrophy through improvement of mitochondrial function
    • Lang H, Li Q, Yu H, Li P, Lu Z, Xiong S, et al. (2015). Activation of TRPV1 attenuates high salt-induced cardiac hypertrophy through improvement of mitochondrial function. Br J Pharmacol 172: 5548-5558. doi: 10.1111/bph.12987
    • (2015) Br J Pharmacol , vol.172 , pp. 5548-5558
    • Lang, H.1    Li, Q.2    Yu, H.3    Li, P.4    Lu, Z.5    Xiong, S.6
  • 20
    • 84879569545 scopus 로고    scopus 로고
    • Immune effector mechanisms implicated in atherosclerosis: From mice to humans
    • Libby P, Lichtman AH, Hansson GK, (2013). Immune effector mechanisms implicated in atherosclerosis: from mice to humans. Immunity 38: 1092-1104.
    • (2013) Immunity , vol.38 , pp. 1092-1104
    • Libby, P.1    Lichtman, A.H.2    Hansson, G.K.3
  • 21
    • 84949535497 scopus 로고    scopus 로고
    • Dietary salt regulates epithelial sodium channels in rat endothelial cells: Adaptation of vasculature to salt
    • Liu HB, Zhang J, Sun YY, Li XY, Jiang S, Liu MY, et al. (2015a). Dietary salt regulates epithelial sodium channels in rat endothelial cells: adaptation of vasculature to salt. Br J Pharmacol 172: 5634-5646. doi: 10.1111/bph.13185
    • (2015) Br J Pharmacol , vol.172 , pp. 5634-5646
    • Liu, H.B.1    Zhang, J.2    Sun, Y.Y.3    Li, X.Y.4    Jiang, S.5    Liu, M.Y.6
  • 22
    • 84949537809 scopus 로고    scopus 로고
    • Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: Role of lectin-like oxidized LDL receptor-1 (LOX-1)
    • Liu Z, Xu S, Huang X, Wang J, Gao S, Li H, et al. (2015b). Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: role of lectin-like oxidized LDL receptor-1 (LOX-1). Br J Pharmacol 172: 5661-5675. doi: 10.1111/bph.13068
    • (2015) Br J Pharmacol , vol.172 , pp. 5661-5675
    • Liu, Z.1    Xu, S.2    Huang, X.3    Wang, J.4    Gao, S.5    Li, H.6
  • 24
    • 84949531129 scopus 로고    scopus 로고
    • Aldosterone down-regulates the slowly activated delayed rectifier potassium current in adult Guinea pig cardiomyocytes
    • Lv Y, Bai S, Zhang H, Zhang H, Meng J, Li L, et al. (2015). Aldosterone down-regulates the slowly activated delayed rectifier potassium current in adult guinea pig cardiomyocytes. Br J Pharmacol 172: 5596-5608. doi: 10.1111/bph.13163
    • (2015) Br J Pharmacol , vol.172 , pp. 5596-5608
    • Lv, Y.1    Bai, S.2    Zhang, H.3    Zhang, H.4    Meng, J.5    Li, L.6
  • 25
    • 84881638673 scopus 로고    scopus 로고
    • Clinical pharmacology of n-3 polyunsaturated fatty acids: Non-lipidic metabolic and hemodynamic effects in human patients
    • Marangoni F, Poli A, (2013). Clinical pharmacology of n-3 polyunsaturated fatty acids: non-lipidic metabolic and hemodynamic effects in human patients. Atheroscler Suppl 14: 230-236.
    • (2013) Atheroscler Suppl , vol.14 , pp. 230-236
    • Marangoni, F.1    Poli, A.2
  • 26
    • 84949492191 scopus 로고    scopus 로고
    • Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases
    • Meng G, Ma Y, Xie L, Ferro A, Ji Y, (2015). Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases. Br J Pharmacol 172: 5501-5511. doi: 10.1111/bph.12900
    • (2015) Br J Pharmacol , vol.172 , pp. 5501-5511
    • Meng, G.1    Ma, Y.2    Xie, L.3    Ferro, A.4    Ji, Y.5
  • 27
    • 0023788435 scopus 로고
    • Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements
    • Miyamoto M, Fujita T, Kimura Y, Maruyama M, Harada H, Sudo Y, et al. (1988). Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell 54: 903-913.
    • (1988) Cell , vol.54 , pp. 903-913
    • Miyamoto, M.1    Fujita, T.2    Kimura, Y.3    Maruyama, M.4    Harada, H.5    Sudo, Y.6
  • 28
    • 53749090260 scopus 로고    scopus 로고
    • Parasympathetic nervous system and heart failure: Pathophysiology and potential implications for therapy
    • Olshansky B, Sabbah HN, Hauptman PJ, Colucci WS, (2008). Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy. Circulation 118: 863-871.
    • (2008) Circulation , vol.118 , pp. 863-871
    • Olshansky, B.1    Sabbah, H.N.2    Hauptman, P.J.3    Colucci, W.S.4
  • 29
    • 84949529440 scopus 로고    scopus 로고
    • Advances in exploring the role of microRNAs in the pathogenesis, diagnosis and therapy of cardiac diseases in China
    • Pan ZW, Lu YJ, Yang BF, (2015). Advances in exploring the role of microRNAs in the pathogenesis, diagnosis and therapy of cardiac diseases in China. Br J Pharmacol 172: 5435-5443. doi: 10.1111/bph.13015
    • (2015) Br J Pharmacol , vol.172 , pp. 5435-5443
    • Pan, Z.W.1    Lu, Y.J.2    Yang, B.F.3
  • 30
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledgebase of drug targets and their ligands
    • NC-IUPHAR
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR. (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-D1106.
    • (2014) Nucl Acids Res , vol.42 , Issue.DATABASE ISSUE , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 31
    • 84949533708 scopus 로고    scopus 로고
    • Genistein alleviates pressure overload-induced cardiac dysfunction and interstitial fibrosis in mice
    • Qin W, Du N, Zhang L, Wu X, Hu Y, Li X, et al. (2015). Genistein alleviates pressure overload-induced cardiac dysfunction and interstitial fibrosis in mice. Br J Pharmacol 172: 5559-5572. doi: 10.1111/bph.13002
    • (2015) Br J Pharmacol , vol.172 , pp. 5559-5572
    • Qin, W.1    Du, N.2    Zhang, L.3    Wu, X.4    Hu, Y.5    Li, X.6
  • 32
    • 84949530737 scopus 로고    scopus 로고
    • Nuciferine relaxes rat mesenteric arteries through endothelium-dependent and -independent mechanisms
    • Wang X, Cheang WS, Yang H, Xiao L, Lai B, Zhang M, et al. (2015a). Nuciferine relaxes rat mesenteric arteries through endothelium-dependent and -independent mechanisms. Br J Pharmacol 172: 5609-5618. doi: 10.1111/bph.13021
    • (2015) Br J Pharmacol , vol.172 , pp. 5609-5618
    • Wang, X.1    Cheang, W.S.2    Yang, H.3    Xiao, L.4    Lai, B.5    Zhang, M.6
  • 33
    • 84949534660 scopus 로고    scopus 로고
    • Oestrogen inhibits BMP4-induced BMP4 expression in cardiomyocytes: A potential mechanism of oestrogen-mediated protection against cardiac hypertrophy
    • Wang YC, Xiao XL, Li N, Yang D, Xing Y, Huo R, et al. (2015b). Oestrogen inhibits BMP4-induced BMP4 expression in cardiomyocytes: a potential mechanism of oestrogen-mediated protection against cardiac hypertrophy. Br J Pharmacol 172: 5586-5595. doi: 10.1111/bph.12983
    • (2015) Br J Pharmacol , vol.172 , pp. 5586-5595
    • Wang, Y.C.1    Xiao, X.L.2    Li, N.3    Yang, D.4    Xing, Y.5    Huo, R.6
  • 34
    • 84949519043 scopus 로고    scopus 로고
    • 2-adrenoceptor signalling in heart failure: Pathophysiology and drug discovery
    • 2-adrenoceptor signalling in heart failure: pathophysiology and drug discovery. Br J Pharmacol 172: 5444-5456. doi: 10.1111/bph.12965
    • (2015) Br J Pharmacol , vol.172 , pp. 5444-5456
    • Woo, A.Y.1    Song, Y.2    Xiao, R.3    Zhu, W.4
  • 36
    • 84949539515 scopus 로고    scopus 로고
    • A metabolite of Danshen formulae attenuates cardiac fibrosis induced by isoprenaline, via a NOX2/ROS/p38 pathway
    • Yin Q, Lu H, Bai Y, Tian A, Yang Q, Wu J, et al. (2015). A metabolite of Danshen formulae attenuates cardiac fibrosis induced by isoprenaline, via a NOX2/ROS/p38 pathway. Br J Pharmacol 172: 5573-5585. doi: 10.1111/bph.13133
    • (2015) Br J Pharmacol , vol.172 , pp. 5573-5585
    • Yin, Q.1    Lu, H.2    Bai, Y.3    Tian, A.4    Yang, Q.5    Wu, J.6
  • 37
    • 84949533120 scopus 로고    scopus 로고
    • The virtual heart as a platform for screening drug cardiotoxicity
    • Yuan Y, Bai X, Luo C, Wang K, Zhang H, (2015). The virtual heart as a platform for screening drug cardiotoxicity. Br J Pharmacol 172: 5531-5547. doi: 10.1111/bph.12996
    • (2015) Br J Pharmacol , vol.172 , pp. 5531-5547
    • Yuan, Y.1    Bai, X.2    Luo, C.3    Wang, K.4    Zhang, H.5
  • 38
    • 84949529544 scopus 로고    scopus 로고
    • The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases
    • Zhang XJ, Jiang DS, Li H, (2015). The interferon regulatory factors as novel potential targets in the treatment of cardiovascular diseases. Br J Pharmacol 172: 5457-5476. doi: 10.1111/bph.12881
    • (2015) Br J Pharmacol , vol.172 , pp. 5457-5476
    • Zhang, X.J.1    Jiang, D.S.2    Li, H.3
  • 39
    • 84949529495 scopus 로고    scopus 로고
    • Protective effect of 23-hydroxybetulinic acid on doxorubicin-induced cardiotoxicity: A correlation with the inhibition of carbonyl reductase-mediated metabolism
    • Zhou F, Hao G, Zhang J, Zheng Y, Wu X, Hao K, et al. (2015). Protective effect of 23-hydroxybetulinic acid on doxorubicin-induced cardiotoxicity: a correlation with the inhibition of carbonyl reductase-mediated metabolism. Br J Pharmacol 172: 5690-5703. doi: 10.1111/bph.12995
    • (2015) Br J Pharmacol , vol.172 , pp. 5690-5703
    • Zhou, F.1    Hao, G.2    Zhang, J.3    Zheng, Y.4    Wu, X.5    Hao, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.