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Volumn 45, Issue 2, 2014, Pages 492-503

Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: A systematic review and meta-analysis

Author keywords

Antiplatelet agents; Intracranial hemorrhages; Stroke

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; PRASUGREL; TICAGRELOR; TICLOPIDINE;

EID: 84893644015     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.002590     Document Type: Review
Times cited : (63)

References (59)
  • 1
    • 0030996001 scopus 로고    scopus 로고
    • Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
    • Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet. 1997;349:1436-1442.
    • (1997) Lancet , vol.349 , pp. 1436-1442
    • Murray, C.J.1    Lopez, A.D.2
  • 2
    • 33745155419 scopus 로고    scopus 로고
    • Primary prevention of ischemic stroke: A guideline from the American Heart Association
    • American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition Physical Activity and Metabolism Council; And the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline
    • Goldstein LB, Adams R, Alberts MJ, Appel LJ, Brass LM, Bushnell CD, et al. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: the American Academy of Neurology affirms the value of this guideline. Stroke. 2006;37:1583-1633.
    • (2006) Stroke , vol.37 , pp. 1583-1633
    • Goldstein, L.B.1    Adams, R.2    Alberts, M.J.3    Appel, L.J.4    Brass, L.M.5    Bushnell, C.D.6
  • 3
    • 33646799069 scopus 로고    scopus 로고
    • Global and regional burden of disease and risk factors 2001: Systematic analysis of population health data
    • Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet. 2006;367:1747-1757.
    • (2006) Lancet , vol.367 , pp. 1747-1757
    • Lopez, A.D.1    Mathers, C.D.2    Ezzati, M.3    Jamison, D.T.4    Murray, C.J.5
  • 4
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: Collaborative meta-analysis of individual participant data from randomised trials
    • Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, Peto R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009;373:1849-1860.
    • (2009) Lancet , vol.373 , pp. 1849-1860
    • Baigent, C.1    Blackwell, L.2    Collins, R.3    Emberson, J.4    Godwin, J.5    Peto, R.6
  • 5
    • 79451474588 scopus 로고    scopus 로고
    • Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: A guideline for healthcare professionals from the American Heart Association/ American Stroke Association
    • American Heart Association Stroke Council, Council on Cardiovascular Nursing, Council on Clinical Cardiology, and Interdisciplinary Council on Quality of Care and Outcomes Research
    • Furie KL, Kasner SE, Adams RJ, Albers GW, Bush RL, Fagan SC, et al; American Heart Association Stroke Council, Council on Cardiovascular Nursing, Council on Clinical Cardiology, and Interdisciplinary Council on Quality of Care and Outcomes Research. Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/ American Stroke Association. Stroke. 2011;42:227-276.
    • (2011) Stroke , vol.42 , pp. 227-276
    • Furie, K.L.1    Kasner, S.E.2    Adams, R.J.3    Albers, G.W.4    Bush, R.L.5    Fagan, S.C.6
  • 6
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration
    • Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ. 2002;324:71-86.
    • (2002) BMJ , vol.324 , pp. 71-86
  • 7
    • 33644867063 scopus 로고    scopus 로고
    • Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: A statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: Co-sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline
    • Sacco RL, Adams R, Albers G, Alberts MJ, Benavente O, Furie K, et al. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Stroke. 2006;37:577-617.
    • (2006) Stroke , vol.37 , pp. 577-617
    • Sacco, R.L.1    Adams, R.2    Albers, G.3    Alberts, M.J.4    Benavente, O.5    Furie, K.6
  • 8
    • 1042267958 scopus 로고    scopus 로고
    • Population based study of early risk of stroke after transient ischaemic attack or minor stroke: Implications for public education and organisation of services
    • Oxford Vascular Study
    • Coull AJ, Lovett JK, Rothwell PM; Oxford Vascular Study. Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services. BMJ. 2004;328:326.
    • (2004) BMJ , vol.328 , pp. 326
    • Coull, A.J.1    Lovett, J.K.2    Rothwell, P.M.3
  • 9
    • 0031929663 scopus 로고    scopus 로고
    • Survival and recurrence after first cerebral infarction: A populationbased study in Rochester Minnesota 1975 through 1989
    • Petty GW, Brown RD Jr, Whisnant JP, Sicks JD, O'Fallon WM, Wiebers DO. Survival and recurrence after first cerebral infarction: a populationbased study in Rochester, Minnesota, 1975 through 1989. Neurology. 1998;50:208-216.
    • (1998) Neurology , vol.50 , pp. 208-216
    • Petty, G.W.1    Brown Jr., R.D.2    Whisnant, J.P.3    Sicks, J.D.4    O'Fallon, W.M.5    Wiebers, D.O.6
  • 10
    • 55449099009 scopus 로고    scopus 로고
    • Secondary stroke prevention: From guidelines to clinical practice
    • Graham GD. Secondary stroke prevention: from guidelines to clinical practice. J Natl Med Assoc. 2008;100:1125-1137.
    • (2008) J Natl Med Assoc , vol.100 , pp. 1125-1137
    • Graham, G.D.1
  • 11
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (caprie)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (caprie). Lancet. 1996;348:1329-1339.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 12
    • 33947328091 scopus 로고    scopus 로고
    • Thienopyridines in cardiovascular disease: Focus on clopidogrel resistance
    • Siller-Matula J, Schrör K, Wojta J, Huber K. Thienopyridines in cardiovascular disease: focus on clopidogrel resistance. Thromb Haemost. 2007;97:385-393.
    • (2007) Thromb Haemost , vol.97 , pp. 385-393
    • Siller-Matula, J.1    Schrör, K.2    Wojta, J.3    Huber, K.4
  • 13
    • 70149101223 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • PLATO Investigators
    • Wallentin L, Becker RC, Budaj A, Cannon CP, Emanuelsson H, Held C, et al; PLATO Investigators. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2009;361:1045-1057.
    • (2009) N Engl J Med , vol.361 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3    Cannon, C.P.4    Emanuelsson, H.5    Held, C.6
  • 14
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • TRITON-TIMI 38 Investigators
    • Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, et al; TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357:2001-2015.
    • (2007) N Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3    Montalescot, G.4    Ruzyllo, W.5    Gottlieb, S.6
  • 15
    • 21644448736 scopus 로고    scopus 로고
    • Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: Results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial
    • JUMBO-TIMI 26 Investigators
    • Wiviott SD, Antman EM, Winters KJ, Weerakkody G, Murphy SA, Behounek BD, et al; JUMBO-TIMI 26 Investigators. Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial. Circulation. 2005;111:3366-3373.
    • (2005) Circulation , vol.111 , pp. 3366-3373
    • Wiviott, S.D.1    Antman, E.M.2    Winters, K.J.3    Weerakkody, G.4    Murphy, S.A.5    Behounek, B.D.6
  • 16
    • 84856158305 scopus 로고    scopus 로고
    • ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent st-segment elevation: The task force for the management of acute coronary syndromes (ACS) in patients presenting without persistent st-segment elevation of the European Society of Cardiology (ESC)
    • Hamm CW, Bassand JP, Agewall S, Bax J, Boersma E, Bueno H, et al. ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent st-segment elevation: the task force for the management of acute coronary syndromes (ACS) in patients presenting without persistent st-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2011;32:2999-3054.
    • (2011) Eur Heart J , vol.32 , pp. 2999-3054
    • Hamm, C.W.1    Bassand, J.P.2    Agewall, S.3    Bax, J.4    Boersma, E.5    Bueno, H.6
  • 17
    • 0035214102 scopus 로고    scopus 로고
    • Combination therapy with clopidogrel and aspirin: Can the CURE results be extrapolated to cerebrovascula patients?
    • Albers GW, Amarenco P. Combination therapy with clopidogrel and aspirin: can the CURE results be extrapolated to cerebrovascula patients? Stroke. 2001;32:2948-2949.
    • (2001) Stroke , vol.32 , pp. 2948-2949
    • Albers, G.W.1    Amarenco, P.2
  • 18
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • PRISMA Group
    • Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535.
    • (2009) BMJ , vol.339
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 19
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta- analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta- analysis. Stat Med. 2002;21:1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 20
    • 78650701981 scopus 로고    scopus 로고
    • Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: The clopidogrel after surgery for coronary artery disease (CASCADE) Trial
    • Kulik A, Le May MR, Voisine P, Tardif JC, Delarochelliere R, Naidoo S, et al. Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) Trial. Circulation. 2010;122:2680-2687.
    • (2010) Circulation , vol.122 , pp. 2680-2687
    • Kulik, A.1    Le May, M.R.2    Voisine, P.3    Tardif, J.C.4    Delarochelliere, R.5    Naidoo, S.6
  • 22
    • 84867177857 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel for acute coronary syndromes without revascularization
    • TRILOGY ACS Investigators
    • Roe MT, Armstrong PW, Fox KA, White HD, Prabhakaran D, Goodman SG, et al; TRILOGY ACS Investigators. Prasugrel versus clopidogrel for acute coronary syndromes without revascularization. N Engl.. 2012;367:1297-1309.
    • (2012) N Engl. , vol.367 , pp. 1297-1309
    • Roe, M.T.1    Armstrong, P.W.2    Fox, K.A.3    White, H.D.4    Prabhakaran, D.5    Goodman, S.G.6
  • 23
    • 84856452781 scopus 로고    scopus 로고
    • Six- month versus 12-month dual antiplatelet therapy after implantation of drug-eluting stents: The Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss after Stenting (EXCELLENT) randomized, multicenter study
    • Gwon HC, Hahn JY, Park KW, Song YB, Chae IH, Lim DS, et al. Six- month versus 12-month dual antiplatelet therapy after implantation of drug-eluting stents: the Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting (EXCELLENT) randomized, multicenter study. Circulation. 2012;125:505-513.
    • (2012) Circulation , vol.125 , pp. 505-513
    • Gwon, H.C.1    Hahn, J.Y.2    Park, K.W.3    Song, Y.B.4    Chae, I.H.5    Lim, D.S.6
  • 24
    • 84860135329 scopus 로고    scopus 로고
    • Short- versus long-term duration of dual-antiplatelet therapy after coronary stenting: A randomized multicenter trial
    • Prolonging Dual Antiplatelet Treatment After Grading Stent-Induced Intimal Hyperplasia Study (PRODIGY) Investigators
    • Valgimigli M, Campo G, Monti M, Vranckx P, Percoco G, Tumscitz C, et al; Prolonging Dual Antiplatelet Treatment After Grading Stent-Induced Intimal Hyperplasia Study (PRODIGY) Investigators. Short- versus long-term duration of dual-antiplatelet therapy after coronary stenting: a randomized multicenter trial. Circulation. 2012;125:2015-2026.
    • (2012) Circulation , vol.125 , pp. 2015-2026
    • Valgimigli, M.1    Campo, G.2    Monti, M.3    Vranckx, P.4    Percoco, G.5    Tumscitz, C.6
  • 25
    • 84879775488 scopus 로고    scopus 로고
    • Clopidogrel with aspirin in acute minor stroke or transient ischemic attack
    • CHANCE Investigators
    • Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, et al; CHANCE Investigators. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013;369:11-19.
    • (2013) N Engl J Med , vol.369 , pp. 11-19
    • Wang, Y.1    Wang, Y.2    Zhao, X.3    Liu, L.4    Wang, D.5    Wang, C.6
  • 26
    • 65249116339 scopus 로고    scopus 로고
    • Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: The Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial
    • WATCH Trial Investigators
    • Massie BM, Collins JF, Ammon SE, Armstrong PW, Cleland JG, Ezekowitz M, et al; WATCH Trial Investigators. Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial. Circulation. 2009;119:1616-1624.
    • (2009) Circulation , vol.119 , pp. 1616-1624
    • Massie, B.M.1    Collins, J.F.2    Ammon, S.E.3    Armstrong, P.W.4    Cleland, J.G.5    Ezekowitz, M.6
  • 28
    • 18244404294 scopus 로고    scopus 로고
    • Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using Doppler embolic signal detection: The Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial
    • Markus HS, Droste DW, Kaps M, Larrue V, Lees KR, Siebler M, et al. Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using Doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial. Circulation. 2005;111:2233-2240.
    • (2005) Circulation , vol.111 , pp. 2233-2240
    • Markus, H.S.1    Droste, D.W.2    Kaps, M.3    Larrue, V.4    Lees, K.R.5    Siebler, M.6
  • 29
    • 33645861080 scopus 로고    scopus 로고
    • Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events
    • CHARISMA Investigators
    • Bhatt DL, Fox KA, Hacke W, Berger PB, Black HR, Boden WE, et al; CHARISMA Investigators. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med. 2006;354:1706-1717.
    • (2006) N Engl J Med , vol.354 , pp. 1706-1717
    • Bhatt, D.L.1    Fox, K.A.2    Hacke, W.3    Berger, P.B.4    Black, H.R.5    Boden, W.E.6
  • 30
    • 20144373281 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
    • CLARITY-TIMI 28 Investigators
    • Sabatine MS, Cannon CP, Gibson CM, López-Sendón JL, Montalescot G, Theroux P, et al; CLARITY-TIMI 28 Investigators. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med. 2005;352:1179-1189.
    • (2005) N Engl J Med , vol.352 , pp. 1179-1189
    • Sabatine, M.S.1    Cannon, C.P.2    Gibson, C.M.3    López-Sendón, J.L.4    Montalescot, G.5    Theroux, P.6
  • 31
    • 27644548513 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: Randomised placebo-controlled trial
    • COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) Collaborative Group
    • Chen ZM, Jiang LX, Chen YP, Xie JX, Pan HC, Peto R, et al; COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) Collaborative Group. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. Lancet. 2005;366:1607-1621.
    • (2005) Lancet , vol.366 , pp. 1607-1621
    • Chen, Z.M.1    Jiang, L.X.2    Chen, Y.P.3    Xie, J.X.4    Pan, H.C.5    Peto, R.6
  • 32
    • 0037145863 scopus 로고    scopus 로고
    • Clopidogrel for the Reduction of Events during Observation. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial
    • CREDO Investigators
    • Steinhubl SR, Berger PB, Mann JT III, Fry ET, DeLago A, Wilmer C, et al; CREDO Investigators. Clopidogrel for the Reduction of Events During Observation. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA. 2002;288:2411-2420.
    • (2002) JAMA , vol.288 , pp. 2411-2420
    • Steinhubl, S.R.1    Berger, P.B.2    Mann III, J.T.3    Fry, E.T.4    Delago, A.5    Wilmer, C.6
  • 33
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK; Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 34
    • 35248821708 scopus 로고    scopus 로고
    • Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): A randomised controlled pilot trial
    • FASTER Investigators
    • Kennedy J, Hill MD, Ryckborst KJ, Eliasziw M, Demchuk AM, Buchan AM; FASTER Investigators. Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial. Lancet Neurol. 2007;6:961-969.
    • (2007) Lancet Neurol , vol.6 , pp. 961-969
    • Kennedy, J.1    Hill, M.D.2    Ryckborst, K.J.3    Eliasziw, M.4    Demchuk, A.M.5    Buchan, A.M.6
  • 35
    • 3242770664 scopus 로고    scopus 로고
    • Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomised, double-blind, placebo- controlled trial
    • MATCH Investigators
    • Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, et al; MATCH Investigators. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo- controlled trial. Lancet. 2004;364:331-337.
    • (2004) Lancet , vol.364 , pp. 331-337
    • Diener, H.C.1    Bogousslavsky, J.2    Brass, L.M.3    Cimminiello, C.4    Csiba, L.5    Kaste, M.6
  • 36
    • 77951001904 scopus 로고    scopus 로고
    • Duration of dual antiplatelet therapy after implantation of drug-eluting stents
    • Park SJ, Park DW, Kim YH, Kang SJ, Lee SW, Lee CW, et al. Duration of dual antiplatelet therapy after implantation of drug-eluting stents. N Engl J Med. 2010;362:1374-1382.
    • (2010) N Engl J Med , vol.362 , pp. 1374-1382
    • Park, S.J.1    Park, D.W.2    Kim, Y.H.3    Kang, S.J.4    Lee, S.W.5    Lee, C.W.6
  • 37
    • 35548995394 scopus 로고    scopus 로고
    • Safety, tolerability, and initial efficacy of azd6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-st-segment elevation acute coronary syndrome: Primary results of the disperse-2 trial
    • Cannon CP, Husted S, Harrington RA, Scirica BM, Emanuelsson H, Peters G, et al. Safety, tolerability, and initial efficacy of azd6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-st-segment elevation acute coronary syndrome: primary results of the disperse-2 trial. J Am Coll Cardiol. 2007;50:1844-1851.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1844-1851
    • Cannon, C.P.1    Husted, S.2    Harrington, R.A.3    Scirica, B.M.4    Emanuelsson, H.5    Peters, G.6
  • 38
    • 85027946204 scopus 로고    scopus 로고
    • Safety and tolerability of atopaxar in the treatment of patients with acute coronary syndromes: The lessons from antagonizing the cellular effects of thrombin-acute coronary syndromes trial
    • O'Donoghue ML, Bhatt DL, Wiviott SD, Goodman SG, Fitzgerald DJ, Angiolillo DJ, et al. Safety and tolerability of atopaxar in the treatment of patients with acute coronary syndromes: the lessons from antagonizing the cellular effects of thrombin-acute coronary syndromes trial. Circulation. 2011;123:1843-1853.
    • (2011) Circulation , vol.123 , pp. 1843-1853
    • O'Donoghue, M.L.1    Bhatt, D.L.2    Wiviott, S.D.3    Goodman, S.G.4    Fitzgerald, D.J.5    Angiolillo, D.J.6
  • 39
    • 77649207578 scopus 로고    scopus 로고
    • Safety and exploratory efficacy of the novel thrombin receptor (PAR-1) antagonist SCH530348 for non-ST-segment elevation acute coronary syndrome
    • Goto S, Yamaguchi T, Ikeda Y, Kato K, Yamaguchi H, Jensen P. Safety and exploratory efficacy of the novel thrombin receptor (PAR-1) antagonist SCH530348 for non-ST-segment elevation acute coronary syndrome. J Atheroscler Thromb. 2010;17:156-164.
    • (2010) J Atheroscler Thromb , vol.17 , pp. 156-164
    • Goto, S.1    Yamaguchi, T.2    Ikeda, Y.3    Kato, K.4    Yamaguchi, H.5    Jensen, P.6
  • 40
  • 42
    • 79958770159 scopus 로고    scopus 로고
    • Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): A randomised, double- blind, parallel-group trial
    • PERFORM Study Investigators
    • Bousser MG, Amarenco P, Chamorro A, Fisher M, Ford I, Fox KM, et al; PERFORM Study Investigators. Terutroban versus aspirin in patients with cerebral ischaemic events (PERFORM): a randomised, double- blind, parallel-group trial. Lancet. 2011;377:2013-2022.
    • (2011) Lancet , vol.377 , pp. 2013-2022
    • Bousser, M.G.1    Amarenco, P.2    Chamorro, A.3    Fisher, M.4    Ford, I.5    Fox, K.M.6
  • 43
    • 84862146372 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack
    • PLATO Study Group
    • James SK, Storey RF, Khurmi NS, Husted S, Keltai M, Mahaffey KW, et al; PLATO Study Group. Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack. Circulation. 2012;125:2914-2921.
    • (2012) Circulation , vol.125 , pp. 2914-2921
    • James, S.K.1    Storey, R.F.2    Khurmi, N.S.3    Husted, S.4    Keltai, M.5    Mahaffey, K.W.6
  • 44
    • 84893647929 scopus 로고    scopus 로고
    • Acute coronary syndromes managed by percutaneous coronary intervention - Prasugrel
    • FDA Division of Cardiovascular and Renal Drugs
    • FDA Division of Cardiovascular and Renal Drugs. Acute coronary syndromes managed by percutaneous coronary intervention - prasugrel. Advisory Committee Briefing Document. 2009:110-112.
    • (2009) Advisory Committee Briefing Document , pp. 110-112
  • 45
    • 84872228959 scopus 로고    scopus 로고
    • Impact of clopidogrel and potent P2Y 12 -inhibitors on mortality and stroke in patients with acute coronary syndrome or undergoing percutaneous coronary intervention: A systematic review and meta-analysis
    • Aradi D, Komócsi A, Vorobcsuk A, Serebruany VL. Impact of clopidogrel and potent P2Y 12 -inhibitors on mortality and stroke in patients with acute coronary syndrome or undergoing percutaneous coronary intervention: a systematic review and meta-analysis. Thromb Haemost. 2013;109:93-101.
    • (2013) Thromb Haemost , vol.109 , pp. 93-101
    • Aradi, D.1    Komócsi, A.2    Vorobcsuk, A.3    Serebruany, V.L.4
  • 46
    • 84862800180 scopus 로고    scopus 로고
    • Dual or mono antiplatelet therapy for patients with acute ischemic stroke or transient ischemic attack: Systematic review and meta-analysis of randomized controlled trials
    • Acute Antiplatelet Stroke Trialists Collaboration
    • Geeganage CM, Diener HC, Algra A, Chen C, Topol EJ, Dengler R, et al; Acute Antiplatelet Stroke Trialists Collaboration. Dual or mono antiplatelet therapy for patients with acute ischemic stroke or transient ischemic attack: systematic review and meta-analysis of randomized controlled trials. Stroke. 2012;43:1058-1066.
    • (2012) Stroke , vol.43 , pp. 1058-1066
    • Geeganage, C.M.1    Diener, H.C.2    Algra, A.3    Chen, C.4    Topol, E.J.5    Dengler, R.6
  • 47
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK; Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345:494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 48
    • 84863126312 scopus 로고    scopus 로고
    • Effects of combined aspirin and clopidogrel therapy on cardiovascular outcomes: A systematic review and meta-analysis
    • Zhou YH, Wei X, Lu J, Ye XF, Wu MJ, Xu JF, et al. Effects of combined aspirin and clopidogrel therapy on cardiovascular outcomes: a systematic review and meta-analysis. PLoS One. 2012;7:e31642.
    • (2012) PLoS One , vol.7
    • Zhou, Y.H.1    Wei, X.2    Lu, J.3    Ye, X.F.4    Wu, M.J.5    Xu, J.F.6
  • 49
    • 41149144263 scopus 로고    scopus 로고
    • Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: A meta-analysis
    • Verro P, Gorelick PB, Nguyen D. Aspirin plus dipyridamole versus aspirin for prevention of vascular events after stroke or TIA: a meta-analysis. Stroke. 2008;39:1358-1363.
    • (2008) Stroke , vol.39 , pp. 1358-1363
    • Verro, P.1    Gorelick, P.B.2    Nguyen, D.3
  • 50
    • 51449085994 scopus 로고    scopus 로고
    • Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the prevention regimen for effectively avoiding second strokes (PROFESS) trial: A double-blind, active and placebo-controlled study
    • Diener HC, Sacco RL, Yusuf S, Cotton D, Ounpuu S, Lawton WA, et al. Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the prevention regimen for effectively avoiding second strokes (PROFESS) trial: a double-blind, active and placebo-controlled study. Lancet Neurol. 2008;7:875-884.
    • (2008) Lancet Neurol , vol.7 , pp. 875-884
    • Diener, H.C.1    Sacco, R.L.2    Yusuf, S.3    Cotton, D.4    Ounpuu, S.5    Lawton, W.A.6
  • 52
    • 0033933641 scopus 로고    scopus 로고
    • Thienopyridines or aspirin to prevent stroke and other serious vascular events in patients at high risk of vascular disease? A systematic review of the evidence from randomized trials
    • Hankey GJ, Sudlow CL, Dunbabin DW. Thienopyridines or aspirin to prevent stroke and other serious vascular events in patients at high risk of vascular disease? A systematic review of the evidence from randomized trials. Stroke. 2000;31:1779-1784.
    • (2000) Stroke , vol.31 , pp. 1779-1784
    • Hankey, G.J.1    Sudlow, C.L.2    Dunbabin, D.W.3
  • 53
    • 79952268676 scopus 로고    scopus 로고
    • Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin
    • Kamal AK, Naqvi I, Husain MR, Khealani BA. Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin. Cochrane Database Syst Rev. 2011;1:CD008076.
    • (2011) Cochrane Database Syst Rev , vol.1
    • Kamal, A.K.1    Naqvi, I.2    Husain, M.R.3    Khealani, B.A.4
  • 54
    • 0030893956 scopus 로고    scopus 로고
    • Comparable studies of the incidence of stroke and its pathological types: Results from an international collaboration. International Stroke Incidence Collaboration
    • Sudlow CL, Warlow CP. Comparable studies of the incidence of stroke and its pathological types: results from an international collaboration. International Stroke Incidence Collaboration. Stroke. 1997;28:491-499.
    • (1997) Stroke , vol.28 , pp. 491-499
    • Sudlow, C.L.1    Warlow, C.P.2
  • 55
    • 84865455487 scopus 로고    scopus 로고
    • Pathology of lacunar ischemic stroke in humans - A systematic review
    • Bailey EL, Smith C, Sudlow CL, Wardlaw JM. Pathology of lacunar ischemic stroke in humans-a systematic review. Brain Pathol. 2012;22:583-591.
    • (2012) Brain Pathol , vol.22 , pp. 583-591
    • Bailey, E.L.1    Smith, C.2    Sudlow, C.L.3    Wardlaw, J.M.4
  • 56
    • 0036193762 scopus 로고    scopus 로고
    • Severe ipsilateral carotid stenosis and middle cerebral artery disease in lacunar ischaemic stroke: Innocent bystanders?
    • Mead GE, Lewis SC, Wardlaw JM, Dennis MS, Warlow CP. Severe ipsilateral carotid stenosis and middle cerebral artery disease in lacunar ischaemic stroke: innocent bystanders? J Neurol. 2002;249:266-271.
    • (2002) J Neurol , vol.249 , pp. 266-271
    • Mead, G.E.1    Lewis, S.C.2    Wardlaw, J.M.3    Dennis, M.S.4    Warlow, C.P.5
  • 57
    • 79960555699 scopus 로고    scopus 로고
    • Adjusted indirect comparison meta-analysis of prasugrel versus ticagrelor for patients with acute coronary syndromes
    • Biondi-Zoccai G, Lotrionte M, Agostoni P, Abbate A, Romagnoli E, Sangiorgi G, et al. Adjusted indirect comparison meta-analysis of prasugrel versus ticagrelor for patients with acute coronary syndromes. Int J Cardiol. 2011;150:325-331.
    • (2011) Int J Cardiol , vol.150 , pp. 325-331
    • Biondi-Zoccai, G.1    Lotrionte, M.2    Agostoni, P.3    Abbate, A.4    Romagnoli, E.5    Sangiorgi, G.6
  • 58
    • 79955772062 scopus 로고    scopus 로고
    • Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified
    • Serebruany VL. Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified. Thromb Haemost. 2011;105:752-759.
    • (2011) Thromb Haemost , vol.105 , pp. 752-759
    • Serebruany, V.L.1
  • 59
    • 80052741598 scopus 로고    scopus 로고
    • Efficacy and safety of intensive antiplatelet therapy with prasugrel from TRITON-TIMI 38 in a core clinical cohort defined by worldwide regulatory agencies
    • Wiviott SD, Desai N, Murphy SA, Musumeci G, Ragosta M, Antman EM, et al. Efficacy and safety of intensive antiplatelet therapy with prasugrel from TRITON-TIMI 38 in a core clinical cohort defined by worldwide regulatory agencies. Am J Cardiol. 2011;108:905-911.
    • (2011) Am J Cardiol , vol.108 , pp. 905-911
    • Wiviott, S.D.1    Desai, N.2    Murphy, S.A.3    Musumeci, G.4    Ragosta, M.5    Antman, E.M.6


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