SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment

Nature Communications

Volumn 6, Issue , 2015, Pages

  Mian, Syed A ^a   Rouault Pierre, Kevin ^b   Smith, Alexander E ^a,c   Seidl, Thomas ^a   Pizzitola, Irene ^b   Kizilors, Aytug ^c   Kulasekararaj, Austin G ^a,c   Bonnet, Dominique ^b   Mufti, Ghulam J ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b THE FRANCIS CRICK INSTITUTE   (United Kingdom)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA6 INTEGRIN; CD34 ANTIGEN; CD38 ANTIGEN; CD45RA ANTIGEN; THY 1 ANTIGEN; PHOSPHOPROTEIN; RNA SPLICING FACTOR; SF3B1 PROTEIN, HUMAN; SMALL NUCLEAR RIBONUCLEOPROTEIN;

CANCER; CELL ORGANELLE; DISEASE TREATMENT; MEDICINE; MUTATION;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLONAL EVOLUTION; COHORT ANALYSIS; CONTROLLED STUDY; ERYTHROCYTE; EVOLUTION; EXOME; GENE; GENE MUTATION; HEMATOPOIETIC STEM CELL; HUMAN; MEGAKARYOCYTE; MOUSE; MUTATIONAL ANALYSIS; MYELODYSPLASTIC SYNDROME; MYELOID PROGENITOR CELL; NONHUMAN; PATHOGENESIS; PROGENY; SF3B1 GENE; SIDEROBLASTIC ANEMIA; XENOTRANSPLANTATION; ACUTE MYELOID LEUKEMIA; AGED; ANIMAL; BONE MARROW; CANCER TRANSPLANTATION; CELL TRANSFORMATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETICS; GENOTYPE; HETEROZYGOSITY LOSS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; MUTATION; YOUNG ADULT;

MUS;

AGED; ANIMALS; BONE MARROW; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENOTYPE; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, MYELOID, ACUTE; LOSS OF HETEROZYGOSITY; MALE; MICE; MIDDLE AGED; MUTATION; MYELODYSPLASTIC SYNDROMES; NEOPLASM TRANSPLANTATION; PHOSPHOPROTEINS; RIBONUCLEOPROTEIN, U2 SMALL NUCLEAR; RNA SPLICING FACTORS; YOUNG ADULT;

EID: 84949495917     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10004     Document Type: Article

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