Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification

Development (Cambridge)

Volumn 142, Issue 23, 2015, Pages 4010-4025

  Zdravkovic, Tamara ^a,b   Nazor, Kristopher L ^c   Larocque, Nicholas ^a,b   Gormley, Matthew ^a,b   Donne, Matthew ^a,b   Hunkapillar, Nathan ^a,b   Giritharan, Gnanaratnam ^d   Bernstein, Harold S ^a,b   Wei, Grace ^a,b   Hebrok, Matthias ^b   Zeng, Xianmin ^e   Genbacev, Olga ^a,b   Mattis, Aras ^a,b   McMaster, Michael T ^a   Krtolica, Ana ^d,h   Valbuena, Diana ^f   Simón, Carlos ^f   Laurent, Louise C ^c,g   Loring, Jeanne F ^c   Fisher, Susan J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d StemLifeLine   (United States)

^e BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^f UNIVERSITY OF VALENCIA   (Spain)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h Omniox   (United States)

Author keywords

Blastomere; Epigenome; Fate specification; Human embryo; Human embryonic stem cell; Human trophoblast stem cell; Transcriptome

Indexed keywords

BETA CATENIN; EOMES PROTEIN; GROWTH DIFFERENTIATION FACTOR 15; T BRACHYURY; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG; CTNNB1 PROTEIN, HUMAN; GDF15 PROTEIN, HUMAN; TRANSCRIPTOME;

ANIMAL CELL; ARTICLE; BLASTOCYST; BLASTOMA; CELL FATE; CELL LINEAGE; CELL SPECIFICITY; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; GENE EXPRESSION; GENETIC TRANSCRIPTION; GERM LAYER; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGENY; STEM CELL LINE; TRANSCRIPTOMICS; TROPHOBLAST; CARDIAC MUSCLE CELL; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DNA MICROARRAY; EMBRYO CULTURE; ENDODERM; FIBROBLAST; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; METABOLISM; NEURAL STEM CELL;

BETA CATENIN; BLASTOCYST; BLASTOMERES; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; DNA METHYLATION; EMBRYO CULTURE TECHNIQUES; EMBRYONIC STEM CELLS; ENDODERM; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; MYOCYTES, CARDIAC; NEURAL STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTION, GENETIC; TRANSCRIPTOME; TROPHOBLASTS;

EID: 84949477631     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.122846     Document Type: Article

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