-
1
-
-
84927615838
-
Antibody-mediated delivery of anti-KRAS-siRNA in vivo overcomes therapy resistance in colon cancer
-
Bäumer, S. et al. Antibody-mediated delivery of anti-KRAS-siRNA in vivo overcomes therapy resistance in colon cancer. Clin. Cancer Res. 21, 1383-1394 (2015).
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 1383-1394
-
-
Bäumer, S.1
-
2
-
-
72149099569
-
The systemic delivery of siRNAs by a cell penetrating peptide, low-molecular-weight protamine
-
Choi, Y.S. et al. The systemic delivery of siRNAs by a cell penetrating peptide, low-molecular-weight protamine. Biomaterials 31, 1429-1443 (2009).
-
(2009)
Biomaterials
, vol.31
, pp. 1429-1443
-
-
Choi, Y.S.1
-
3
-
-
84870575710
-
Exosome-mediated delivery of siRNA in vitro and in vivo
-
El-Andaloussi, S. et al. Exosome-mediated delivery of siRNA in vitro and in vivo. Nat. Protoc. 7, 2112-2126 (2012).
-
(2012)
Nat. Protoc.
, vol.7
, pp. 2112-2126
-
-
El-Andaloussi, S.1
-
4
-
-
38449109145
-
Exploring cell type-specific internalizing antibodies for targeted delivery of siRNA
-
Liu, B. Exploring cell type-specific internalizing antibodies for targeted delivery of siRNA. Brief. Funct. Genomics Proteomics 6, 112-119 (2007).
-
(2007)
Brief. Funct. Genomics Proteomics
, vol.6
, pp. 112-119
-
-
Liu, B.1
-
5
-
-
84865173355
-
A simple and rapid nonviral approach to efficiently transfect primary tissue-derived cells using polyethylenimine
-
Hsu, C.Y. & Uludag, H. A simple and rapid nonviral approach to efficiently transfect primary tissue-derived cells using polyethylenimine. Nat. Protoc. 7, 935-945 (2012).
-
(2012)
Nat. Protoc.
, vol.7
, pp. 935-945
-
-
Hsu, C.Y.1
Uludag, H.2
-
6
-
-
82955187719
-
Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma
-
Di Paolo, D. et al. Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma. Mol. Ther. 19, 2201-2212 (2011).
-
(2011)
Mol. Ther.
, vol.19
, pp. 2201-2212
-
-
Di Paolo, D.1
-
7
-
-
84862690092
-
Antibody-drug conjugates: Basic concepts, examples and future perspectives
-
Casi, G. & Neri, D. Antibody-drug conjugates: basic concepts, examples and future perspectives. J. Control. Release 161, 422-428 (2012).
-
(2012)
J. Control. Release
, vol.161
, pp. 422-428
-
-
Casi, G.1
Neri, D.2
-
8
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
-
Song, E. et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat. Biotechnol. 23, 709-717 (2005).
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 709-717
-
-
Song, E.1
-
9
-
-
0036667102
-
Cetuximab (Imclone/Merck/Bristol-Myers Squibb)
-
Kies, M.S. & Harari, P.M. Cetuximab (Imclone/Merck/Bristol-Myers Squibb). Curr. Opin. Investig. Drugs 3, 1092-1100 (2002).
-
(2002)
Curr. Opin. Investig. Drugs
, vol.3
, pp. 1092-1100
-
-
Kies, M.S.1
Harari, P.M.2
-
10
-
-
77949756180
-
Novel siRNA delivery system to target podocytes in vivo
-
Hauser, P.V. et al. Novel siRNA delivery system to target podocytes in vivo. PLoS ONE 5, e9463 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e9463
-
-
Hauser, P.V.1
-
11
-
-
84860211700
-
Targeted delivery of PLK1-siRNA by ScFv suppresses Her2+ breast cancer growth and metastasis
-
Yao, Y.D. et al. Targeted delivery of PLK1-siRNA by ScFv suppresses Her2+ breast cancer growth and metastasis. Sci. Transl. Med. 4, 130ra48 (2012).
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 130ra48
-
-
Yao, Y.D.1
-
12
-
-
34247255870
-
Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1
-
Peer, D., Zhu, P., Carman, C.V., Lieberman, J. & Shimaoka, M. Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1. Proc. Natl. Acad. Sci. USA 104, 4095-4100 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4095-4100
-
-
Peer, D.1
Zhu, P.2
Carman, C.V.3
Lieberman, J.4
Shimaoka, M.5
-
13
-
-
34247873185
-
Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies
-
Kittler, R. et al. Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. Nat. Methods 4, 337-344 (2007).
-
(2007)
Nat. Methods
, vol.4
, pp. 337-344
-
-
Kittler, R.1
-
14
-
-
84863908472
-
Phase II study of ganitumab, a fully human anti-type-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors
-
Tap, W.D. et al. Phase II study of ganitumab, a fully human anti-type-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors. J. Clin. Oncol. 30, 1849-1856 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 1849-1856
-
-
Tap, W.D.1
-
15
-
-
78649846572
-
Insulin-like growth factor 1 receptor antibody induces rhabdomyosarcoma cell death via a process involving AKT and bcl-x(L)
-
Mayeenuddin, L.H., Yu, Y., Kang, Z., Helman, L.J. & Cao, L. Insulin-like growth factor 1 receptor antibody induces rhabdomyosarcoma cell death via a process involving AKT and bcl-x(L). Oncogene 29, 6367-6377 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 6367-6377
-
-
Mayeenuddin, L.H.1
Yu, Y.2
Kang, Z.3
Helman, L.J.4
Cao, L.5
-
16
-
-
0025078257
-
Monoclonal antibody alpha IR-3 inhibits the ability of insulin-like growth factor II to stimulate a signal from the type i receptor without inhibiting its binding
-
Steele-Perkins, G. & Roth, R.A. Monoclonal antibody alpha IR-3 inhibits the ability of insulin-like growth factor II to stimulate a signal from the type I receptor without inhibiting its binding. Biochem. Biophys. Res. Commun. 171, 1244-1251 (1990).
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.171
, pp. 1244-1251
-
-
Steele-Perkins, G.1
Roth, R.A.2
-
17
-
-
34347367165
-
Monoclonal antibody alpha IR-3 inhibits non-small cell lung cancer growth in vitro and in vivo
-
Zia, F. et al. Monoclonal antibody alpha IR-3 inhibits non-small cell lung cancer growth in vitro and in vivo. J. Cell. Biochem. Suppl. 24, 269-275 (1996).
-
(1996)
J. Cell. Biochem. Suppl.
, vol.24
, pp. 269-275
-
-
Zia, F.1
-
18
-
-
84911466839
-
In vivo shRNA screens in solid tumors
-
Gargiulo, G., Serresi, M., Cesaroni, M., Hulsman, D. & van Lohuizen, M. In vivo shRNA screens in solid tumors. Nat. Protoc. 9, 2880-2902 (2014).
-
(2014)
Nat. Protoc.
, vol.9
, pp. 2880-2902
-
-
Gargiulo, G.1
Serresi, M.2
Cesaroni, M.3
Hulsman, D.4
Van Lohuizen, M.5
-
19
-
-
80052627990
-
Current progress of siRNA/shRNA therapeutics in clinical trials
-
Burnett, J.C., Rossi, J.J. & Tiemann, K. Current progress of siRNA/shRNA therapeutics in clinical trials. Biotechnol. J. 6, 1130-1146 (2011).
-
(2011)
Biotechnol. J.
, vol.6
, pp. 1130-1146
-
-
Burnett, J.C.1
Rossi, J.J.2
Tiemann, K.3
-
20
-
-
84877120847
-
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
-
Tabernero, J. et al. First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement. Cancer Discov. 3, 406-417 (2013).
-
(2013)
Cancer Discov.
, vol.3
, pp. 406-417
-
-
Tabernero, J.1
-
21
-
-
49549117077
-
T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice
-
Kumar, P. et al. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell 134, 577-586 (2008).
-
(2008)
Cell
, vol.134
, pp. 577-586
-
-
Kumar, P.1
-
22
-
-
84934439055
-
Designing efficient and specific endoribonuclease-prepared siRNAs
-
Surendranath, V., Theis, M., Habermann, B.H. & Buchholz, F. Designing efficient and specific endoribonuclease-prepared siRNAs. Methods Mol. Biol. 942, 193-204 (2013).
-
(2013)
Methods Mol. Biol.
, vol.942
, pp. 193-204
-
-
Surendranath, V.1
Theis, M.2
Habermann, B.H.3
Buchholz, F.4
-
23
-
-
33947701466
-
Housing, husbandry and handling of rodents for behavioral experiments
-
Deacon, R.M. Housing, husbandry and handling of rodents for behavioral experiments. Nat. Protoc. 1, 936-946 (2006).
-
(2006)
Nat. Protoc.
, vol.1
, pp. 936-946
-
-
Deacon, R.M.1
-
24
-
-
81755161347
-
The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth
-
Schmidt, L.H. et al. The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth. J. Thorac. Oncol. 6, 1984-1992 (2011).
-
(2011)
J. Thorac. Oncol.
, vol.6
, pp. 1984-1992
-
-
Schmidt, L.H.1
-
25
-
-
84937865328
-
A limited role for the cell cycle regulator cyclin A1 in murine leukemogenesis
-
Bäumer, N. et al. A limited role for the cell cycle regulator cyclin A1 in murine leukemogenesis. PLoS ONE 10, e0129147 (2015).
-
(2015)
PLoS ONE
, vol.10
-
-
Bäumer, N.1
-
26
-
-
0037767890
-
Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6
-
Bäumer, N. et al. Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6. Development 130, 2903-2915 (2003).
-
(2003)
Development
, vol.130
, pp. 2903-2915
-
-
Bäumer, N.1
-
27
-
-
47249095860
-
A simple protocol for paraffin-embedded myelin sheath staining with osmium tetroxide for light microscope observation
-
Di Scipio, F., Raimondo, S., Tos, P. & Geuna, S. A simple protocol for paraffin-embedded myelin sheath staining with osmium tetroxide for light microscope observation. Microsc. Res. Tech. 71, 497-502 (2008).
-
(2008)
Microsc. Res. Tech.
, vol.71
, pp. 497-502
-
-
Di Scipio, F.1
Raimondo, S.2
Tos, P.3
Geuna, S.4
|