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Volumn 108, Issue 2, 2013, Pages 177-185

American Journal of Gastroenterology Lecture: Intestinal microbiota and the role of fecal microbiota transplant (FMT) in treatment of C. difficile infection

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Indexed keywords

ANTIBIOTIC AGENT;

EID: 84873570579     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2012.450     Document Type: Review
Times cited : (150)

References (54)
  • 1
    • 84869395353 scopus 로고    scopus 로고
    • Should we standardize the 1700-year-old fecal microbiota transplantation?
    • Zhang F, Luo W, Shi Y et al. Should we standardize the 1700-year-old fecal microbiota transplantation? Am J Gastroenterol 2012; 107: 1755.
    • (2012) Am J Gastroenterol. , vol.107 , pp. 1755
    • Zhang, F.1    Luo, W.2    Shi, Y.3
  • 2
    • 84862276328 scopus 로고    scopus 로고
    • Structure, function and diversity of the healthy human microbiome
    • The Human Microbiome Project Consortium.
    • The Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486: 207-14.
    • (2012) Nature , vol.486 , pp. 207-214
  • 5
    • 32944466887 scopus 로고    scopus 로고
    • Ecological and evolutionary forces shaping microbial diversity in the human intestine
    • DOI 10.1016/j.cell.2006.02.017, PII S0092867406001929
    • Ley RE, Peterson DA, Gordon JI. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 2006; 124: 837-48. (Pubitemid 43261456)
    • (2006) Cell , vol.124 , Issue.4 , pp. 837-848
    • Ley, R.E.1    Peterson, D.A.2    Gordon, J.I.3
  • 6
    • 14844351844 scopus 로고    scopus 로고
    • Spatial organization of bacterial flora in normal and inflamed intestine: A fluorescence in situ hybridization study in mice
    • Swidsinski A, Loening-Bauke V, Lochs H, Hale LP. Spatial organization of bacterial fl ora in normal and infl amed intestine: A fl uorescence in sitühybridization study in mice. World J Gastroenterol 2005; 11: 1131-40. (Pubitemid 40352998)
    • (2005) World Journal of Gastroenterology , vol.11 , Issue.8 , pp. 1131-1140
    • Swidsinski, A.1    Loening-Baucke, V.2    Lochs, H.3    Hale, L.P.4
  • 9
    • 78650847143 scopus 로고    scopus 로고
    • Mode of delivery aff ects the bacterial community in the newborn gut
    • Biasucci G, Rubini M, Riboni S et al. Mode of delivery aff ects the bacterial community in the newborn gut. Early Hum Dev 2010; 86 (Suppl 1): 13-5.
    • (2010) Early Hum Dev , vol.86 , Issue.SUPPL. 1 , pp. 13-15
    • Biasucci, G.1    Rubini, M.2    Riboni, S.3
  • 10
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • WüGD, Chen J, Hoff mann C et al. Linking long-term dietary patterns with gut microbial enterotypes. Science 2011; 334: 105-8.
    • (2011) Science , vol.334 , pp. 105-108
    • Wü, G.D.1    Chen, J.2    Hoffmann, C.3
  • 12
    • 0035793372 scopus 로고    scopus 로고
    • Molecular analysis of commensal host-microbial relationships in the intestine
    • DOI 10.1126/science.291.5505.881
    • Hooper LV, Wong MH, Th elin A et al. Molecular analysis of commensal host-microbial relationships in the intestine. Science 2001; 291: 881-4. (Pubitemid 32120760)
    • (2001) Science , vol.291 , Issue.5505 , pp. 881-884
    • Hooper, L.V.1    Wong, M.H.2    Thelin, A.3    Hansson, L.4    Falk, P.G.5    Gordon, J.I.6
  • 13
    • 0035843993 scopus 로고    scopus 로고
    • Commensal host-bacterial relationships in the gut
    • DOI 10.1126/science.1058709
    • Hooper LV, Gordon JI. Commensal host-bacterial relationships in the gut. Science 2001; 292: 1115-8. (Pubitemid 32440925)
    • (2001) Science , vol.292 , Issue.5519 , pp. 1115-1118
    • Hooper, L.V.1    Gordon, J.I.2
  • 14
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • DOI 10.1016/j.cell.2005.05.007, PII S0092867405004514
    • Mazmanian SK, Lin CH, Tzianabos AO, Kasper DL. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005; 122: 107-18. (Pubitemid 40977944)
    • (2005) Cell , vol.122 , Issue.1 , pp. 107-118
    • Mazmanian, S.K.1    Cui, H.L.2    Tzianabos, A.O.3    Kasper, D.L.4
  • 15
    • 37849032964 scopus 로고    scopus 로고
    • Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth-factor beta
    • Zeuthen LH, Fink LN, Frokiner H. Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth-factor beta. Immunology 2008; 123: 197-208.
    • (2008) Immunology. , vol.123 , pp. 197-208
    • Zeuthen, L.H.1    Fink, L.N.2    Frokiner, H.3
  • 17
    • 36749024487 scopus 로고    scopus 로고
    • Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota
    • DOI 10.1016/j.chom.2007.10.010, PII S1931312807002806
    • Bates JM, Akerland J, M ittge E, Guillemin K. Intestinal alkaline phosphatase detoxifi es lipopolysaccharide and prevents infl ammation in zebrafi sh in response to the gut microbiota. Cell Host Microbe 2007; 2: 371-82. (Pubitemid 350215326)
    • (2007) Cell Host and Microbe , vol.2 , Issue.6 , pp. 371-382
    • Bates, J.M.1    Akerlund, J.2    Mittge, E.3    Guillemin, K.4
  • 18
    • 34447292335 scopus 로고    scopus 로고
    • Impact of selected Lactobacillus and Bifidobacterium species on Listeria monocytogenes infection and the mucosal immune response
    • DOI 10.1111/j.1574-695X.2007.00264.x
    • Corr SC, Gahan CG, Hill C. Impact of selected Lactobacillus and Bifi dobacterium species on Listeria monocytogenes infection and the mucosal immune response. FEMS Immunol Med Microbiol 2007; 50: 380-8. (Pubitemid 47041463)
    • (2007) FEMS Immunology and Medical Microbiology , vol.50 , Issue.3 , pp. 380-388
    • Corr, S.C.1    Gahan, C.G.M.2    Hill, C.3
  • 19
    • 80054103361 scopus 로고    scopus 로고
    • Obesity and the gut microbiota
    • Flint HJ. Obesity and the gut microbiota. J Clin Gastroenterol 2011; 45: S128-32.
    • (2011) J Clin Gastroenterol , vol.45
    • Flint, H.J.1
  • 20
    • 17844404232 scopus 로고    scopus 로고
    • Gut microorganisms, mammalian metabolism and personalized health care
    • DOI 10.1038/nrmicro1152
    • Nicholson JK, Holmes E, Wilson ID. Gut microorganisms, mammalian metabolism, and personalized health care. Nat Rev Microbiol 2005; 3: 431-8. (Pubitemid 40590386)
    • (2005) Nature Reviews Microbiology , vol.3 , Issue.5 , pp. 431-438
    • Nicholson, J.K.1    Holmes, E.2    Wilson, I.D.3
  • 21
    • 82955233474 scopus 로고    scopus 로고
    • Fecal Microbiota Transplantation (FMT) Workgroup. Treating Clostridium diffi cile infection with fecal microbiota transplantation
    • Bakken JS, Borody T, Brandt LJ et al. Fecal Microbiota Transplantation (FMT) Workgroup. Treating Clostridium diffi cile infection with fecal microbiota transplantation. Clin Gastroenterol and Hepatol 2011; 9: 1044-9.
    • (2011) Clin Gastroenterol and Hepatol. , vol.9 , pp. 1044-9
    • Bakken, J.S.1    Borody, T.2    Brandt, L.J.3
  • 22
    • 0001412472 scopus 로고
    • Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis
    • Eiseman B, Silen W, Bascom GS et al. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery 1958; 44: 854-9.
    • (1958) Surgery. , vol.44 , pp. 854-859
    • Eiseman, B.1    Silen, W.2    Bascom, G.S.3
  • 23
    • 0021097993 scopus 로고
    • Relapsing Clostridium diffi cile enterocolitis cured by rectal infusion of homologous faeces
    • Schwan A, Sjolin S, Trottestam Üet al. Relapsing Clostridium diffi cile enterocolitis cured by rectal infusion of homologous faeces. Lancet 1983; 2: 845.
    • (1983) Lancet. , vol.2 , pp. 845
    • Schwan, A.1    Sjolin, S.2    Trottestam, U.3
  • 24
    • 0037373020 scopus 로고    scopus 로고
    • Recurrent Clostridium difficile colitis: Case series involving 18 patients treated with donor stool administered via a nasogastric tube
    • DOI 10.1086/367657
    • Aas J, Gessert CE, Bakken JS. Recurrent Clostridium diffi cile colitis: Case series involving 18 patients treated with donor stool administered via a nasogastric tube. Clin Infect Dis 2003; 36: 580-5. (Pubitemid 36259562)
    • (2003) Clinical Infectious Diseases , vol.36 , Issue.5 , pp. 580-585
    • Aas, J.1    Gessert, C.E.2    Bakken, J.S.3
  • 25
    • 0033766160 scopus 로고    scopus 로고
    • Treatment of recurrent Clostridium diffi cile -associated diarrhea by administration of donated stool directly through a colonoscope
    • Persky SE, Brandt LJ. Treatment of recurrent Clostridium diffi cile -associated diarrhea by administration of donated stool directly through a colonoscope. Am J Gastroenterol 2000; 95: 3283-5.
    • (2000) Am J Gastroenterol. , vol.95 , pp. 3283-5
    • Persky, S.E.1    Brandt, L.J.2
  • 26
    • 77950861655 scopus 로고    scopus 로고
    • Success of self-administered home fecal transplantation for chronic Clostridium diffi cile infection
    • Silverman MS, Davis I, Pillai DR. Success of self-administered home fecal transplantation for chronic Clostridium diffi cile infection. Clin Gastroenterol Hepatol 2010; 8: 471-3.
    • (2010) Clin Gastroenterol Hepatol. , vol.8 , pp. 471-3
    • Silverman, M.S.1    Davis, I.2    Pillai, D.R.3
  • 27
    • 80054111987 scopus 로고    scopus 로고
    • Fecal microbiota transplantation for recurrent Clostridium diffi cile infection
    • Brandt LJ, Reddy S. Fecal microbiota transplantation for recurrent Clostridium diffi cile infection. J Clin Gastroenterol 2011; 45: S159-67.
    • (2011) J Clin Gastroenterol. , vol.45
    • Brandt, L.J.1    Reddy, S.2
  • 28
    • 80054736926 scopus 로고    scopus 로고
    • Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium diffi cile infection
    • Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium diffi cile infection. Clin Infect Dis 2011; 53: 994-1002.
    • (2011) Clin Infect Dis. , vol.53 , pp. 994-1002
    • Gough, E.1    Shaikh, H.2    Manges, A.R.3
  • 29
    • 84857640098 scopus 로고    scopus 로고
    • Fecal Transplantation, through colonoscopy, is eff ective therapy for recurrent Clostridium diffi cile infection
    • Mattila E, Uusitalo-Sepp ä l ä R, Wuorela M et al. Fecal Transplantation, through colonoscopy, is eff ective therapy for recurrent Clostridium diffi cile infection. Gastroenterology 2010; 142: 490-6.
    • (2010) Gastroenterology , vol.142 , pp. 490-496
    • Mattila, E.1    Uusitalo-Seppälä, R.2    Wuorela, M.3
  • 30
    • 84872818314 scopus 로고    scopus 로고
    • Fecal microbiome transplantation for recurrent Clostridium diffi cile infection: Report on a case series
    • 23 November 2012 pii S1075 - 9964 12)00153-12)00159 doi: 10.1016/j.anaerobe.2012.11.004 (e-pub ahead of print)
    • Rubin TA, Gessert CE, Aas J, Bakken JS. Fecal microbiome transplantation for recurrent Clostridium diffi cile infection: Report on a case series. Anaerobe; 23 November 2012 pii S1075-9964(12)00153-9; doi: 10.1016/j.anaerobe. 2012.11.004 (e-pub ahead of print).
    • Anaerobe
    • Rubin, T.A.1    Gessert, C.E.2    Aas, J.3    Bakken, J.S.4
  • 32
    • 0032614375 scopus 로고    scopus 로고
    • Recurrent Clostridium diffi cile Disease. Epidemiology and Clinical Characteristics
    • McFarland LV, Surawicz CM, Rubin M et al. Recurrent Clostridium diffi cile Disease. Epidemiology and Clinical Characteristics. Infect Contr and Hosp Epidemiol 1999; 20: 43-50.
    • (1999) Infect Contr and Hosp Epidemiol. , vol.20 , pp. 43-50
    • McFarland, L.V.1    Surawicz, C.M.2    Rubin, M.3
  • 33
    • 84868158515 scopus 로고    scopus 로고
    • Targeted restoration of the intestinal microbiota with a simple, defi ned bacteriotherapy resolves relapsing Clostridium diffi cile disease in mice
    • doi: 10.1371/journal.ppat.1002995
    • Lawley TD, Clare S, Walker AW et al. Targeted restoration of the intestinal microbiota with a simple, defi ned bacteriotherapy resolves relapsing Clostridium diffi cile disease in mice. PLoS Pathog 8: E1002995; doi: 10.1371/journal.ppat.1002995.
    • PLoS Pathog , vol.8
    • Lawley, T.D.1    Clare, S.2    Walker, A.W.3
  • 35
    • 80054111810 scopus 로고    scopus 로고
    • Fermentation in the human large intestine. Its physiologic consequences and the potential contribution of probiotics
    • Macfarlane GT, Macfarlane S. Fermentation in the human large intestine. Its physiologic consequences and the potential contribution of probiotics. J Clin Gastrooenterol 2011; 45: S120-7.
    • (2011) J Clin Gastrooenterol. , vol.45
    • Macfarlane, G.T.1    Macfarlane, S.2
  • 36
    • 84862309942 scopus 로고    scopus 로고
    • Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium diffi cile infection
    • Hamilton MJ, Weingarden AR, Sadowsky MJ et al. Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium diffi cile infection. Am J Gastroenterol 2012; 107: 761-7.
    • (2012) Am J Gastroenterol , vol.107 , pp. 761-767
    • Hamilton, M.J.1    Weingarden, A.R.2    Sadowsky, M.J.3
  • 37
    • 84863719891 scopus 로고    scopus 로고
    • Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium diffi cile infection
    • Brandt LJ, Aroniadis OC, Mellow M et al. Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium diffi cile infection. Am J Gastroenterol. 2012; 107: 1079-87.
    • (2012) Am J Gastroenterol. , vol.107 , pp. 1079-87
    • Brandt, L.J.1    Aroniadis, O.C.2    Mellow, M.3
  • 38
    • 70350707366 scopus 로고    scopus 로고
    • Struggling with recurrent Clostridium diffi cile infections: Is donor faeces the solution?
    • van Nood E, Speelman P, Kuiper EJ et al. Struggling with recurrent Clostridium diffi cile infections: Is donor faeces the solution? Euro Surveill 2009; 14: Pii:19316.
    • (2009) Euro Surveill. , vol.14 , pp. 19316
    • Van Nood, E.1    Speelman, P.2    Kuiper, E.J.3
  • 39
    • 80052024909 scopus 로고    scopus 로고
    • Endoscopic Fecal Microbiota Transplantation: "First-Line" treatment for severe Clostridium difficile infection
    • Brandt LJ, Borody TJ, Campbell J. Endoscopic Fecal Microbiota Transplantation: " First-Line " treatment for severe Clostridium diffi cile infection. J Clin Gastroenterol. 2011; 45: 655-7.
    • (2011) J Clin Gastroenterol. , vol.45 , pp. 655-657
    • Brandt, L.J.1    Borody, T.J.2    Campbell, J.3
  • 40
    • 38649115342 scopus 로고    scopus 로고
    • Microbial infl uences in infl ammatory bowel diseases
    • Sartour RB. Microbial infl uences in infl ammatory bowel diseases. Gastroenterology 2008; 134: 577-94.
    • (2008) Gastroenterology. , vol.134 , pp. 577-94
    • Sartour, R.B.1
  • 41
    • 80054857288 scopus 로고    scopus 로고
    • Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
    • Rajiilic-Stojanovic M, Biagi E, Heilig HG et al. Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology 2011; 141: 1792-801.
    • (2011) Gastroenterology , vol.141 , pp. 1792-1801
    • Rajiilic-Stojanovic, M.1    Biagi, E.2    Heilig, H.G.3
  • 42
    • 79952397377 scopus 로고    scopus 로고
    • The enteric microbiota in the pathogenesis and management of constipation
    • Quigley E. The enteric microbiota in the pathogenesis and management of constipation. Best Pract Res Clin Gastroenterol 2011; 25: 119-26.
    • (2011) Best Pract Res Clin Gastroenterol. , vol.25 , pp. 119-26
    • Quigley, E.1
  • 43
    • 84864750634 scopus 로고    scopus 로고
    • Faecal transplant eases symptoms of parkinson's
    • 2796 19 January 2011
    • Anathaswamy A. Faecal transplant eases symptoms of Parkinson's. New Scientist; issue 2796, 19 January 2011.
    • New Scientist
    • Anathaswamy, A.1
  • 44
    • 84873568840 scopus 로고    scopus 로고
    • Bacteriotherapy in chronic fatigue syndrome: A retrospective review
    • A1481)
    • Borody TJ, Nowak A, Torres M et al. Bacteriotherapy in chronic fatigue syndrome: A retrospective review. Am J Gastroenterol 2012; 107 (Suppl 1) , S591-592 (A1481).
    • (2012) Am J Gastroenterol. , vol.107 , Issue.SUPPL. 1
    • Borody, T.J.1    Nowak, A.2    Torres, M.3
  • 45
    • 84856966182 scopus 로고    scopus 로고
    • Fecal microbiota transplantation (FMT) in multiple sclerosis (MS) [abstract]
    • Borody TJ, Leis S, Campbell J et al. Fecal microbiota transplantation (FMT) in multiple sclerosis (MS) [abstract]. Am J Gastroenterol 2011; 106: S352.
    • (2011) Am J Gastroenterol. , vol.106
    • Borody, T.J.1    Leis, S.2    Campbell, J.3
  • 46
    • 84856966182 scopus 로고    scopus 로고
    • Myoclonus-dystonia (M-D) mediated by GI microbiota diarrhoea treatment improves M-D symptoms
    • Borody TJ, Rosen DM, Torres M et al. Myoclonus-dystonia (M-D) mediated by GI microbiota diarrhoea treatment improves M-D symptoms. Am J Gastroenterol 2011; 106: S352.
    • (2011) Am J Gastroenterol. , vol.106
    • Borody, T.J.1    Rosen, D.M.2    Torres, M.3
  • 47
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • DOI 10.1038/nature05414, PII NATURE05414
    • Turnbaugh PJ, Ley RE, Mahowald MA et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006; 444: 1027-31. (Pubitemid 46018515)
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 48
    • 84866738529 scopus 로고    scopus 로고
    • Transfer of intestinal microbiota from lean donors increases insulin sensitivity in subjects with metabolic syndrome
    • Vrieze A, van Nood E, Holleman F et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in subjects with metabolic syndrome. Gastroenterology 2012; 143: 913-916.
    • (2012) Gastroenterology. , vol.143 , pp. 913-916
    • Vrieze, A.1    Van Nood, E.2    Holleman, F.3
  • 49
    • 0036061028 scopus 로고    scopus 로고
    • Gastrointestinal micro fl ora studies in late-onset autism
    • Finegold SM, Molitors D, Song Y. Gastrointestinal micro fl ora studies in late-onset autism. Clin Infect Dis. 2002; 35: S6-16.
    • (2002) Clin Infect Dis. , vol.35
    • Finegold, S.M.1    Molitors, D.2    Song, Y.3
  • 50
    • 84856971587 scopus 로고    scopus 로고
    • Reversal of idiopathic thrombocytopenic purpura (ITP) with fecal microbiota transplantation (FMT) [abstract]
    • Borody TJ, Campbell J, Torres M et al. Reversal of idiopathic thrombocytopenic purpura (ITP) with fecal microbiota transplantation (FMT) [abstract]. Am J Gastroenterol 2011; 106: S352.
    • (2011) Am J Gastroenterol. , vol.106
    • Borody, T.J.1    Campbell, J.2    Torres, M.3
  • 51
    • 65449159712 scopus 로고    scopus 로고
    • The Relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease
    • Collins SM, Bercik P. The Relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease. Gastroenterology 2009; 136: 2003-14.
    • (2009) Gastroenterology. , vol.136 , pp. 2003-14
    • Collins, S.M.1    Bercik, P.2
  • 52
    • 80052965474 scopus 로고    scopus 로고
    • Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
    • Bravo JA, Forsythe P, Chew MV et al. Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci USA 2011; 108: 16050-5.
    • (2011) Proc Natl Acad Sci USA. , vol.108 , pp. 16050-5
    • Bravo, J.A.1    Forsythe, P.2    Chew, M.V.3
  • 53
    • 81855194317 scopus 로고    scopus 로고
    • The anxiolytic eff ect of Bifi dobacterium longum NCC3001 involves vagal pathways for gut-brain communication
    • Bercik P, Park AJ, Sinclair D et al. The anxiolytic eff ect of Bifi dobacterium longum NCC3001 involves vagal pathways for gut-brain communication. Neurogastroenterol Motil 2011; 23: 1132-9.
    • (2011) Neurogastroenterol Motil. , vol.23 , pp. 1132-9
    • Bercik, P.1    Park, A.J.2    Sinclair, D.3
  • 54
    • 79959201412 scopus 로고    scopus 로고
    • Human nutrition, the gut micro biome, and immune system: Envisioning the future
    • KaüAL, Ahern PP, Griff en NW et al. Human nutrition, the gut micro biome, and immune system: Envisioning the future. Nature 2011; 474: 327-36.
    • (2011) Nature , vol.474 , pp. 327-336
    • Kaü, A.L.1    Ahern, P.P.2    Griffen, N.W.3


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