Evidence that a lipolytic enzyme-hematopoietic-specific phospholipase C-β2-promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes

Leukemia

Volumn 30, Issue 4, 2016, Pages 919-928

  Adamiak, M ^a   Poniewierska Baran, A ^a   Borkowska, S ^a   Schneider, G ^a   Abdelbaset Ismail, A ^a   Suszynska, M ^b   Abdel Latif, A ^b   Kucia, M ^a,c   Ratajczak, J ^a   Ratajczak, M Z ^a,c  

^a UNIVERSITY OF LOUISVILLE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENZYME; CHEMOKINE RECEPTOR CXCR4; COMPLEMENT COMPONENT C5A; GLYCOSYLPHOSPHATIDYLINOSITOL; MEMBRANE LIPID; PHOSPHOLIPASE C BETA2; STROMAL CELL DERIVED FACTOR 1; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4; PHOSPHOLIPASE C BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CELL PERMEABILIZATION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DEGRANULATION; ENZYME RELEASE; FEMALE; GRANULOCYTE; HEMATOPOIETIC STEM CELL; LIPID RAFT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL MOBILIZATION; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL ADHESION; CELL CULTURE; CELL MEMBRANE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; ENZYME IMMUNOASSAY; ENZYMOLOGY; FLOW CYTOMETRY; HUMAN; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; APOPTOSIS; BONE MARROW; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COMPLEMENT C5A; FLOW CYTOMETRY; GRANULOCYTES; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOLIPASE C BETA; SIGNAL TRANSDUCTION;

EID: 84949255244     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2015.315     Document Type: Article

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