T cell mediated autoimmune glomerular disease in mice

Current Protocols in Immunology

Volumn 2014, Issue , 2014, Pages 15.27.1-15.27.19

  Ooi, Joshua ^a   Gan, Poh Yi ^a   Odobasic, Dragana ^a   Holdsworth, Stephen R ^a,b   Kitching, A Richard ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b SOUTHERN HEALTH   (Australia)

Author keywords

Autoimmunity; Cell mediated immunity; Glomerulonephritis; T lymphocytes

Indexed keywords

COLLAGEN TYPE 4; FC RECEPTOR IIB; HLA DR ANTIGEN; HLA DRB1 ANTIGEN; MYELOPEROXIDASE; RECOMBINANT PROTEIN; AUTOANTIBODY; AUTOANTIGEN;

ARTICLE; AUTOIMMUNITY; CELL DIFFERENTIATION; CELL EXPANSION; CELLULAR IMMUNITY; ENZYME ACTIVITY; EXPERIMENTAL AUTOIMMUNE GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; LEUKOCYTE ACTIVATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; T LYMPHOCYTE; ANIMAL; AUTOIMMUNE DISEASE; GLOMERULONEPHRITIS; HUMAN; IMMUNOLOGY; MOUSE; PATHOLOGY;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; GLOMERULAR BASEMENT MEMBRANE; GLOMERULONEPHRITIS; HUMANS; MICE; T-LYMPHOCYTES;

EID: 84949208815     PISSN: 19343671     EISSN: 1934368X     Source Type: Journal    
DOI: 10.1002/0471142735.im1527s107     Document Type: Article

References (34)

1. Aitman, T.J., Dong, R., Vyse, T.J., Norsworthy, P.J., Johnson, M.D., Smith, J., Mangion, J., Roberton-Lowe, C., Marshall, A.J., Petretto, E., Hodges, M.D., Bhangal, G., Patel, S.G., Sheehan-Rooney, K., Duda, M., Cook, P.R., Evans, D.J., Domin, J., Flint, J., Boyle, J.J., Pusey, C.D., Cook, H.T. 2006. Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature 439:851-855.
2. Apostolopoulos, J., Ooi, J.D., Odobasic, D., Holdsworth, S.R., Kitching, A.R. 2006. The isolation and purification of biologically active recombinant and native autoantigens for the study of autoimmune disease. J. Immunol. Methods 308:167-178.
3. Bolton, W.K., Tucker, F.L., Sturgill, B.C. 1984. New avian model of experimental glomerulonephritis consistent with mediation by cellular immunity. Nonhumorally mediated glomerulonephritis in chickens. J. Clin. Invest. 73:1263-1276.
4. Bradley, P.P., Priebat, D.A., Christensen, R.D., Rothstein, G. 1982. Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol. 78:206-209.
5. Couser, W.G. 1999. Glomerulonephritis. Lancet 353:1509-1515
6. Cunningham, M.A., Huang, X.R., Dowling, J.P., Tipping, P.G., Holdsworth, S.R. 1999. Prominence of cell-mediated immunity effectors in "pauci-immune" glomerulonephritis. J. Am. Soc. Nephrol. 10:499-506.
7. Dean, E.G., Wilson, G.R., Li, M., Edgtton, K.L., O'Sullivan, K.M., Hudson, B.G., Holdsworth, S.R., Kitching, A.R. 2005. Experimental autoimmune Goodpasture's disease: A pathogenetic role for both effector cells and antibody in injury. Kidney Int. 67:566-575.
8. Falk, R.J. and Jennette, J.C. 1988. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N. Engl. J. Med. 318:1651-1657.
9. Falk, R.J., Terrell, R.S., Charles, L.A., Jennette, J.C. 1990. Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc. Natl. Acad. Sci. U.S.A. 87:4115-4119.
10. Gan, P.Y., Steinmetz, O.M., Tan, D.S., O'Sullivan, K.M., Ooi, J.D., Iwakura, Y., Kitching, A.R., Holdsworth, S.R. 2010. Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis. J. Am. Soc. Nephrol. 21:925-931.
11. Gan, P.Y., Summers, S.A., Ooi, J.D., O'Sullivan, K.M., Tan, D.S., Muljadi, R.C., Odobasic, D., Kitching, A.R., Holdsworth, S.R. 2012. Mast cells contribute to peripheral tolerance and attenuate autoimmune vasculitis. J. Am. Soc. Nephrol. 23:1955-1966.
12. Heeringa, P., Brouwer, E., Klok, P.A., Huitema, M.G., van den Born, J., Weening, J.J., Kallenberg, C.G. 1996. Autoantibodies to myeloperoxidase aggravate mild anti-glomerular- basement-membrane-mediated glomerular injury in the rat. Am. J. Pathol. 149:1695-1706.
13. Hopfer, H., Maron, R., Butzmann, U., Helmchen, U., Weiner, H.L., Kalluri, R. 2003. The importance of cell-mediated immunity in the course and severity of autoimmune antiglomerular basement membrane disease in mice. FASEB J. 17:860-868.
14. Hopfer, H., Holzer, J., Hunemorder, S., Paust, H.J., Sachs, M., Meyer-Schwesinger, C., Turner, J.E., Panzer, U., Mittrucker, H.W. 2012. Characterization of the renal CD4(+) T-cell response in experimental autoimmune glomerulonephritis. Kidney Int. 82:60-71.
15. Jennette, J.C. and Falk, R.J. 1997. Small-vessel vasculitis. N. Engl. J. Med. 337:1512-1523.
16. Kalluri, R., Danoff, T.M., Okada, H., Neilson, E.G. 1997. Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice. J. Clin. Invest. 100:2263-2275.
17. Kessenbrock, K., Krumbholz, M., Schonermarck, U., Back, W., Gross, W.L., Werb, Z., Grone, H.J., Brinkmann, V., Jenne, D.E. 2009. Netting neutrophils in autoimmune small-vessel vasculitis. Nat. Med. 15:623-625.
18. Kettle, A.J. andWinterbourn, C.C. 1994. Assays for the chlorination activity of myeloperoxidase. In Methods in Enzymology, Vol. 233 (L. Packer, ed.) pp. 502-512. Academic Press, San Diego.
19. Kitching, A.R., Turner, A.L., Semple, T., Li, M., Edgtton, K.L., Wilson, G.R., Timoshanko, J.R., Hudson, B.G., Holdsworth, S.R. 2004. Experimental autoimmune anti-glomerular basement membrane glomerulonephritis: A protective role for IFN-gamma. J. Am. Soc. Nephrol. 15:1764-1774.
20. Miner, J.H. and Sanes, J.R. 1994. Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches. J. Cell Biol. 127:879-891.
21. Neale, T.J., Tipping, P.G., Carson, S.D., Holdsworth, S.R. 1988. Participation of cellmediated immunity in deposition of fibrin in glomerulonephritis. Lancet 2:421-424.
22. Ooi, J.D., Phoon, R.K., Holdsworth, S.R., Kitching, A.R. 2009. IL-23, not IL-12, directs autoimmunity to the Goodpasture antigen. J. Am. Soc. Nephrol. 20:980-989.
23. Ooi, J.D., Chang, J., Hickey, M.J., Borza, D.B., Fugger, L., Holdsworth, S.R., Kitching, A.R. 2012. The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis. Proc. Natl. Acad. Sci. U.S.A. 109:E2615-E2624.
24. Ooi, J.D., Chang, J., O'Sullivan, K.M., Pedchenko, V., Hudson, B.G., Vandenbark, A.A., Fugger, L., Holdsworth, S.R., Kitching, A.R. 2013. The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. J. Am. Soc. Nephrol. 24:419-431.
25. Reynolds, J., Tam, F.W., Chandraker, A., Smith, J., Karkar, A.M., Cross, J., Peach, R., Sayegh, M.H., Pusey, C.D. 2000. CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis. J. Clin. Invest. 105:643-651.
26. Reynolds, J., Khan, S.B., Allen, A.R., Benjamin, C.D., Pusey, C.D. 2004. Blockade of the CD154-CD40 costimulatory pathway prevents the development of experimental autoimmune glomerulonephritis. Kidney Int. 66:1444-1452.
27. Reynolds, J., Cook, P.R., Behmoaras, J., Smith, J., Bhangal, G., Tadros, S., Tee, J., Salama, A.D., Evans, D.J., Aitman, T.J., Cook, H.T., Pusey, C.D. 2012. Genetic susceptibility to experimental autoimmune glomerulonephritis in the Wistar Kyoto rat. Am. J. Pathol. 180:1843-1851.
28. Ruth, A.J., Kitching, A.R., Kwan, R.Y., Odobasic, D., Ooi, J.D., Timoshanko, J.R., Hickey, M.J., Holdsworth, S.R. 2006. Antineutrophil cytoplasmic antibodies and effector CD4+ cells play nonredundant roles in antimyeloperoxidase crescentic glomerulonephritis. J. Am. Soc. Nephrol. 17:1940-1949.
29. Sado, Y., Naito, I., andOkigaki, T. 1989. Transfer of anti-glomerular basement membrane antibodyinduced glomerulonephritis in inbred rats with isologous antibodies from the urine of nephritic rats. J. Pathol. 158:325-332.
30. Steblay, R.W. 1962. Glomerulonephritis induced in sheep by injections of heterologous glomerular basement membrane and Freund's complete adjuvant. J. Exp. Med. 116:253-272.
31. Tan, D.S., Gan, P.Y., O'Sullivan, K.M., Hammett, M.V., Summers, S.A., Ooi, J.D., Lundgren, B.A., Boyd, R.L., Scott, H.S., Kitching, A.R., Chidgey, A.P., Holdsworth, S.R. 2013. Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN. J. Am. Soc. Nephrol. 24:573-585.
32. Valtieri, M., Tweardy, D.J., Caracciolo, D., Johnson, K., Mavilio, F., Altmann, S., Santoli, D., Rovera, G. 1987. Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line. J. Immunol. 138:3829-3835.
33. Wu, J., Hicks, J., Borillo, J., Glass, W.F., II, and Lou, Y.H. 2002. CD4(+) T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis. J. Clin. Invest. 109:517-524.
34. Xiao, H., Heeringa, P., Hu, P., Liu, Z., Zhao, M., Aratani, Y., Maeda, N., Falk, R.J., Jennette, J.C. 2002. Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J. Clin. Invest. 110:955-963.