The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 39, 2012, Pages

  Ooi, Joshua D ^a   Chang, Janet ^a   Hickey, Michael J ^a   Borza, Dorin Bogdan ^c   Fugger, Lars ^d   Holdsworth, Stephen R ^a,b   Kitching, A Richard ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b MONASH MEDICAL CENTRE   (Australia)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Autoimmunity; Lymphocytes; Macrophages; T helper 1 cells

Indexed keywords

AMINO ACID; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 17; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY; RAG1 PROTEIN;

ANCA ASSOCIATED VASCULITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMYELOPEROXIDASE GLOMERULONEPHRITIS; ARTICLE; BASEMENT MEMBRANE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GLOMERULONEPHRITIS; IMMUNIZATION; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; AUTOANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; EPITOPE MAPPING; EPITOPES, T-LYMPHOCYTE; GLOMERULONEPHRITIS; IMMUNITY, CELLULAR; MICE; MICE, KNOCKOUT; MICROSCOPIC POLYANGIITIS; NEUTROPHIL ACTIVATION; NEUTROPHILS; PEROXIDASE;

MURINAE; MUS;

EID: 84866880246     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210147109     Document Type: Article

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