메뉴 건너뛰기




Volumn 15, Issue 4, 2015, Pages

Calcineurin signaling: Lessons from Candida species

Author keywords

Calcineurin; Candida; Crz1; Drug tolerance; Hyphal growth; Virulence

Indexed keywords

CALCINEURIN; ECHINOCANDIN B DERIVATIVE; POLYENE ANTIBIOTIC AGENT; PYRROLE DERIVATIVE;

EID: 84949197587     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1093/femsyr/fov016     Document Type: Short Survey
Times cited : (48)

References (37)
  • 1
    • 79957992936 scopus 로고    scopus 로고
    • A novel specificity protein 1 (SP1)-like gene regulating protein kinase C-1 (Pkc1)- dependent cell wall integrity and virulence factors in Cryptococcus neoformans
    • Adler A, Park YD, Larsen P, et al. A novel specificity protein 1 (SP1)-like gene regulating protein kinase C-1 (Pkc1)- dependent cell wall integrity and virulence factors in Cryptococcus neoformans. J Biol Chem 2011;286:20977-90.
    • (2011) J Biol Chem , vol.286 , pp. 20977-20990
    • Adler, A.1    Park, Y.D.2    Larsen, P.3
  • 2
    • 33745625877 scopus 로고    scopus 로고
    • Role of calcineurin in stress resistance, morphogenesis, and virulence of a Candida albicans wild-type strain
    • Bader T, Schroppel K, Bentink S, et al. Role of calcineurin in stress resistance, morphogenesis, and virulence of a Candida albicans wild-type strain. Infect Immun 2006;74:4366-9.
    • (2006) Infect Immun , vol.74 , pp. 4366-4369
    • Bader, T.1    Schroppel, K.2    Bentink, S.3
  • 3
    • 84908242930 scopus 로고    scopus 로고
    • Antifungal resistance: more research needed
    • Barnes RA, Gow NA, Denning DW, et al. Antifungal resistance: more research needed. Lancet 2014;384:1427.
    • (2014) Lancet , vol.384 , pp. 1427
    • Barnes, R.A.1    Gow, N.A.2    Denning, D.W.3
  • 4
    • 76449084150 scopus 로고    scopus 로고
    • The inositol regulon controls viability in Candida glabrata
    • Bethea EK, Carver BJ, Montedonico AE, et al. The inositol regulon controls viability in Candida glabrata. Microbiology 2010;156:452-62.
    • (2010) Microbiology , vol.156 , pp. 452-462
    • Bethea, E.K.1    Carver, B.J.2    Montedonico, A.E.3
  • 5
    • 0037805741 scopus 로고    scopus 로고
    • Calcineurin is essential for Candida albicans survival in serum and virulence
    • Blankenship JR, Wormley FL, Boyce MK, et al. Calcineurin is essential for Candida albicans survival in serum and virulence. Eukaryot Cell 2003;2:422-30.
    • (2003) Eukaryot Cell , vol.2 , pp. 422-430
    • Blankenship, J.R.1    Wormley, F.L.2    Boyce, M.K.3
  • 6
    • 78650808399 scopus 로고    scopus 로고
    • Echinocandin antifungal drugs in fungal infections: a comparison
    • Chen SC, Slavin MA, Sorrell TC. Echinocandin antifungal drugs in fungal infections: a comparison. Drugs 2011;71:11-41.
    • (2011) Drugs , vol.71 , pp. 11-41
    • Chen, S.C.1    Slavin, M.A.2    Sorrell, T.C.3
  • 7
    • 79957942182 scopus 로고    scopus 로고
    • Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis
    • Chen YL, Brand A, Morrison EL, et al. Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis. Eukaryot Cell 2011;10:803-19.
    • (2011) Eukaryot Cell , vol.10 , pp. 803-819
    • Chen, Y.L.1    Brand, A.2    Morrison, E.L.3
  • 8
    • 84928920293 scopus 로고    scopus 로고
    • Candida albicans OPI1 regulates filamentous growth and virulence in vaginal infections, but not inositol biosynthesis
    • Chen YL, de Bernardis F, Yu SJ, et al. Candida albicans OPI1 regulates filamentous growth and virulence in vaginal infections, but not inositol biosynthesis. PLoS One 2015;10:e0116974.
    • (2015) PLoS One , vol.10 , pp. e0116974
    • Chen, Y.L.1    de Bernardis, F.2    Yu, S.J.3
  • 9
    • 84883416226 scopus 로고    scopus 로고
    • Convergent evolution of calcineurin pathway roles in thermotolerance and virulence in Candida glabrata
    • Chen YL, Konieczka JH, Springer DJ, et al. Convergent evolution of calcineurin pathway roles in thermotolerance and virulence in Candida glabrata. G3 2012;2:675-91.
    • (2012) G3 , vol.2 , pp. 675-691
    • Chen, Y.L.1    Konieczka, J.H.2    Springer, D.J.3
  • 10
    • 79952194334 scopus 로고    scopus 로고
    • On the roles of calcineurin in fungal growth and pathogenesis
    • Chen YL, Kozubowski L, Cardenas ME, et al. On the roles of calcineurin in fungal growth and pathogenesis. Curr Fungal Infect Rep 2010;4:244-55.
    • (2010) Curr Fungal Infect Rep , vol.4 , pp. 244-255
    • Chen, Y.L.1    Kozubowski, L.2    Cardenas, M.E.3
  • 11
    • 84883250066 scopus 로고    scopus 로고
    • Calcineurin governs thermotolerance and virulence of Cryptococcus gattii
    • Chen YL, Lehman VN, Lewit Y, et al. Calcineurin governs thermotolerance and virulence of Cryptococcus gattii. G3 2013;3:527-39.
    • (2013) G3 , vol.3 , pp. 527-539
    • Chen, Y.L.1    Lehman, V.N.2    Lewit, Y.3
  • 12
    • 84903608440 scopus 로고    scopus 로고
    • Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis
    • Chen YL, Yu SJ, Huang HY, et al. Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis. Eukaryot Cell 2014;13:844-54.
    • (2014) Eukaryot Cell , vol.13 , pp. 844-854
    • Chen, Y.L.1    Yu, S.J.2    Huang, H.Y.3
  • 13
    • 47049104386 scopus 로고    scopus 로고
    • Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus
    • Cramer RA, Jr, Perfect BZ, Pinchai N, et al. Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus. Eukaryot Cell 2008;7: 1085-97.
    • (2008) Eukaryot Cell , vol.7 , pp. 1085-1097
    • Cramer, R.A.1    Perfect, B.Z.2    Pinchai, N.3
  • 14
    • 84876434668 scopus 로고    scopus 로고
    • Regulation of cation balance in Saccharomyces cerevisiae
    • Cyert MS, Philpott CC. Regulation of cation balance in Saccharomyces cerevisiae. Genetics 2013;193:677-713.
    • (2013) Genetics , vol.193 , pp. 677-713
    • Cyert, M.S.1    Philpott, C.C.2
  • 15
    • 84926058258 scopus 로고    scopus 로고
    • Howto bolster the antifungal pipeline
    • Denning DW, Bromley MJ. Howto bolster the antifungal pipeline. Science 2015;347:1414-6.
    • (2015) Science , vol.347 , pp. 1414-1416
    • Denning, D.W.1    Bromley, M.J.2
  • 16
    • 82455174370 scopus 로고    scopus 로고
    • Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans
    • Ding C, Vidanes GM, Maguire SL, et al. Conserved and divergent roles of Bcr1 and CFEM proteins in Candida parapsilosis and Candida albicans. PLoS One 2011;6:e28151.
    • (2011) PLoS One , vol.6 , pp. e28151
    • Ding, C.1    Vidanes, G.M.2    Maguire, S.L.3
  • 18
    • 0028856422 scopus 로고
    • A new human gene from the Down syndrome critical region encodes a prolinerich protein highly expressed in fetal brain and heart
    • Fuentes JJ, Pritchard MA, Planas AM, et al. A new human gene from the Down syndrome critical region encodes a prolinerich protein highly expressed in fetal brain and heart. Human Mol Genet 1995;4:1935-44.
    • (1995) Human Mol Genet , vol.4 , pp. 1935-1944
    • Fuentes, J.J.1    Pritchard, M.A.2    Planas, A.M.3
  • 19
    • 84905574813 scopus 로고    scopus 로고
    • The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity
    • Goldman A, Roy J, Bodenmiller B, et al. The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity. Mol Cell 2014;55: 422-35.
    • (2014) Mol Cell , vol.55 , pp. 422-435
    • Goldman, A.1    Roy, J.2    Bodenmiller, B.3
  • 20
    • 34547829234 scopus 로고    scopus 로고
    • Ribosomal protein genes in the yeast Candida albicans may be activated by a heterodimeric transcription factor related to Ino2 and Ino4 from S. cerevisiae.
    • Hoppen J, Dietz M, Warsow G, et al. Ribosomal protein genes in the yeast Candida albicans may be activated by a heterodimeric transcription factor related to Ino2 and Ino4 from S. cerevisiae. Mol Genet Genomics 2007;278:317-30.
    • (2007) Mol Genet Genomics , vol.278 , pp. 317-330
    • Hoppen, J.1    Dietz, M.2    Warsow, G.3
  • 21
    • 84926026219 scopus 로고    scopus 로고
    • Calcineurin as a multifunctional regulator: unraveling novel functions in fungal stress responses, hyphal growth, drug resistance, and pathogenesis
    • Juvvadi PR, Lamoth F, Steinbach WJ. Calcineurin as a multifunctional regulator: unraveling novel functions in fungal stress responses, hyphal growth, drug resistance, and pathogenesis. Fungal Biol Rev 2014;28:56-69.
    • (2014) Fungal Biol Rev , vol.28 , pp. 56-69
    • Juvvadi, P.R.1    Lamoth, F.2    Steinbach, W.J.3
  • 22
    • 0034234963 scopus 로고    scopus 로고
    • A conserved family of calcineurin regulators
    • Kingsbury TJ, Cunningham KW. A conserved family of calcineurin regulators. Gene Dev 2000;14:1595-604.
    • (2000) Gene Dev , vol.14 , pp. 1595-1604
    • Kingsbury, T.J.1    Cunningham, K.W.2
  • 23
    • 0001018554 scopus 로고
    • Calcineurin: a calcium- and calmodulin-binding protein of the nervous system
    • Klee CB, Crouch TH, Krinks MH. Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. P Natl Acad Sci USA 1979;76:6270-3.
    • (1979) P Natl Acad Sci USA , vol.76 , pp. 6270-6273
    • Klee, C.B.1    Crouch, T.H.2    Krinks, M.H.3
  • 24
    • 84884681688 scopus 로고    scopus 로고
    • Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides
    • Lee SC, Li A, Calo S, et al. Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. PLoS Pathog 2013;9:e1003625.
    • (2013) PLoS Pathog , vol.9 , pp. e1003625
    • Lee, S.C.1    Li, A.2    Calo, S.3
  • 25
    • 0025809351 scopus 로고
    • The Saccharomyces cerevisiae genes (CMP1 and CMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B
    • Liu Y, Ishii S, Tokai M, et al. The Saccharomyces cerevisiae genes (CMP1 and CMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B. Mol Gen Genet 1991;227:52-9.
    • (1991) Mol Gen Genet , vol.227 , pp. 52-59
    • Liu, Y.1    Ishii, S.2    Tokai, M.3
  • 26
    • 34250204870 scopus 로고    scopus 로고
    • Transcriptional rewiring of fungal galactose-metabolism circuitry
    • Martchenko M, Levitin A, Hogues H, et al. Transcriptional rewiring of fungal galactose-metabolism circuitry. Curr Biol 2007;17:1007-13.
    • (2007) Curr Biol , vol.17 , pp. 1007-1013
    • Martchenko, M.1    Levitin, A.2    Hogues, H.3
  • 27
    • 33847232569 scopus 로고    scopus 로고
    • Transcriptional activation domains of the Candida albicans Gcn4p and Gal4p homologs
    • Martchenko M, Levitin A, Whiteway M. Transcriptional activation domains of the Candida albicans Gcn4p and Gal4p homologs. Eukaryot Cell 2007;6:291-301.
    • (2007) Eukaryot Cell , vol.6 , pp. 291-301
    • Martchenko, M.1    Levitin, A.2    Whiteway, M.3
  • 28
    • 0031008864 scopus 로고    scopus 로고
    • Calcineurin is required for virulence of Cryptococcus neoformans
    • Odom A, Muir S, Lim E, et al. Calcineurin is required for virulence of Cryptococcus neoformans. EMBO J 1997;16:2576-89.
    • (1997) EMBO J , vol.16 , pp. 2576-2589
    • Odom, A.1    Muir, S.2    Lim, E.3
  • 29
    • 33750582208 scopus 로고    scopus 로고
    • Calcineurin promotes infection of the cornea by Candida albicans and can be targeted to enhance fluconazole therapy
    • Onyewu C, Afshari NA, Heitman J. Calcineurin promotes infection of the cornea by Candida albicans and can be targeted to enhance fluconazole therapy. Antimicrob Agents Ch 2006;50:3963-5.
    • (2006) Antimicrob Agents Ch , vol.50 , pp. 3963-3965
    • Onyewu, C.1    Afshari, N.A.2    Heitman, J.3
  • 30
    • 0038016755 scopus 로고    scopus 로고
    • Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence
    • Sanglard D, Ischer F, Marchetti O, et al. Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence. Mol Microbiol 2003;48: 959-76.
    • (2003) Mol Microbiol , vol.48 , pp. 959-976
    • Sanglard, D.1    Ischer, F.2    Marchetti, O.3
  • 31
    • 39849097989 scopus 로고    scopus 로고
    • Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA
    • Soriani FM, Malavazi I, da Silva FerreiraME, et al. Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA. Mol Microbiol 2008;67:1274-91.
    • (2008) Mol Microbiol , vol.67 , pp. 1274-1291
    • Soriani, F.M.1    Malavazi, I.2    da Silva, FerreiraM.E.3
  • 32
    • 33746239608 scopus 로고    scopus 로고
    • Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus
    • Steinbach WJ, Cramer RA, Jr, Perfect BZ, et al. Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus. Eukaryot Cell 2006;5:1091-103.
    • (2006) Eukaryot Cell , vol.5 , pp. 1091-1103
    • Steinbach, W.J.1    Cramer, R.A.2    Perfect, B.Z.3
  • 33
    • 34249069582 scopus 로고    scopus 로고
    • Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections
    • Steinbach WJ, Reedy JL, Cramer RA, Jr, et al. Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections. Nat Rev 2007;5:418-30.
    • (2007) Nat Rev , vol.5 , pp. 418-430
    • Steinbach, W.J.1    Reedy, J.L.2    Cramer, R.A.3
  • 35
    • 0026088571 scopus 로고
    • The OPI1 gene of Saccharomyces cerevisiae, a negative regulator of phospholipid biosynthesis, encodes a protein containing polyglutamine tracts and a leucine zipper
    • White MJ, Hirsch JP, Henry SA. The OPI1 gene of Saccharomyces cerevisiae, a negative regulator of phospholipid biosynthesis, encodes a protein containing polyglutamine tracts and a leucine zipper. J Biol Chem 1991;266:863-72.
    • (1991) J Biol Chem , vol.266 , pp. 863-872
    • White, M.J.1    Hirsch, J.P.2    Henry, S.A.3
  • 36
    • 84865019052 scopus 로고    scopus 로고
    • Comparative analysis of calcineurin signaling between Candida dubliniensis and Candida albicans
    • Zhang J, Heitman J, Chen YL. Comparative analysis of calcineurin signaling between Candida dubliniensis and Candida albicans. Commun Integr Biol 2012;5:122-6.
    • (2012) Commun Integr Biol , vol.5 , pp. 122-126
    • Zhang, J.1    Heitman, J.2    Chen, Y.L.3
  • 37
    • 84865626877 scopus 로고    scopus 로고
    • Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae
    • Zhang J, Silao FG, Bigol UG, et al. Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae. PLoS One 2012;7:e44192.
    • (2012) PLoS One , vol.7 , pp. e44192
    • Zhang, J.1    Silao, F.G.2    Bigol, U.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.