Simulation of the microscopic process during initiation of stent thrombosis

Computers in Biology and Medicine

Volumn 56, Issue , 2015, Pages 182-191

  Chesnutt, Jennifer K W ^a   Han, Hai Chao ^a,b  

^a The University of Texas at San Antonio   (United States)

^b University of Texas Health Science Center   (United States)

Author keywords

Computational simulation; Coronary arteries; Discrete element model; Endothelium activation; Shear induced platelet activation; Stent thrombosis

Indexed keywords

CHEMICAL ACTIVATION; COMPUTATIONAL FLUID DYNAMICS; DEPOSITS; DISEASES; PLATELETS; SHEAR STRESS; STENTS; STRUTS;

COMPUTATIONAL SIMULATION; CORONARY ARTERIES; DISCRETE ELEMENT MODELING; PLATELET ACTIVATION; STENT THROMBOSIS;

BLOOD VESSELS;

ARTICLE; BLOOD CLOTTING; COMPUTER SIMULATION; CORONARY ARTERY; CORONARY STENTING; DRUG ELUTING STENT; ENDOTHELIAL DYSFUNCTION; ERYTHROCYTE; HUMAN; MICROSCOPY; SHEAR RATE; SHEAR STRESS; STENT THROMBOSIS; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; VASCULAR ENDOTHELIUM; BIOLOGICAL MODEL; CORONARY ARTERY THROMBOSIS; CORONARY BLOOD VESSEL; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; STENT; THROMBOCYTE;

BLOOD PLATELETS; CORONARY THROMBOSIS; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; HUMANS; MODELS, CARDIOVASCULAR; STENTS;

EID: 84949116786     PISSN: 00104825     EISSN: 18790534     Source Type: Journal    
DOI: 10.1016/j.compbiomed.2014.11.006     Document Type: Article

References (49)

1. Palmaz J.C. Intravascular stents in the last and the next 10 years. J. Endovasc. Ther. 2004, 11(Suppl 2):SII200-SII206.
2. Lewis G. Materials, fluid dynamics, and solid mechanics aspects of coronary artery stents: a state-of-the-art review. J. Biomed. Mater. Res. Part B-Appl. Biomater. 2008, 86B(2):569-590.
3. Valenti R., et al. Clinical and angiographic outcomes of patients treated with everolimus-eluting stents or first-generation Paclitaxel-eluting stents for unprotected left main disease. J. Am. Coll. Cardiol. 2012, 60(14):1217-1222.
4. Kohn C.G., et al. Short-term consequences of angiographically-confirmed coronary stent thrombosis. PLoS One 2013, 8(10):e77330.
5. Inoue T., et al. Vascular inflammation and repair: implications for re-endothelialization, restenosis, and stent thrombosis. JACC Cardiovasc. Interv. 2011, 4(10):1057-1066.
6. Nakano M., et al. Causes of early stent thrombosis in patients presenting with acute coronary syndrome: an ex vivo human autopsy study. J. Am. Coll. Cardiol. 2014, 63(23):2510-2520.
7. Van der Heiden K., et al. The effects of stenting on shear stress: relevance to endothelial injury and repair. Cardiovasc. Res. 2013, 99(2):269-275.
8. Koskinas K.C., et al. Role of endothelial shear stress in stent restenosis and thrombosis: pathophysiologic mechanisms and implications for clinical translation. J. Am. Coll. Cardiol. 2012, 59(15):1337-1349.
9. Otsuka F., et al. Pathologic etiologies of late and very late stent thrombosis following first-generation drug-eluting stent placement. Thrombosis 2012, 2012:608593.
10. Jimenez J.M., Davies P.F. Hemodynamically driven stent strut design. Ann. Biomed. Eng. 2009, 37(8):1483-1494.
11. Kolandaivelu K., et al. Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings. Circulation 2011, 123(13):1400-1409.
12. Wootton D.M., Ku D.N. Fluid mechanics of vascular systems, diseases, and thrombosis. Annu. Rev. Biomed. Eng. 1999, 1:299-329.
13. Duraiswamy N., et al. Spatial distribution of platelet deposition in stented arterial models under physiologic flow. Ann. Biomed. Eng. 2005, 33(12):1767-1777.
14. Chesnutt J.K.W., Marshall J.S. Blood cell transport and aggregation using discrete ellipsoidal particles. Comput. Fluids 2009, 38(9):1782-1794.
15. Chesnutt J.K.W., Marshall J.S. Effect of particle collisions and aggregation on red blood cell passage through a bifurcation. Microvasc. Res. 2009, 78(3):301-313.
16. Chesnutt J.K.W., Han H.-C. Effect of red blood cells on platelet activation and thrombus formation in tortuous arterioles. Front. Bioeng. Biotechnol. 2013, 1:1-12. (Article ID: 18).
17. Chiastra C., et al. Computational fluid dynamic simulations of image-based stented coronary bifurcation models. J. R. Soc. Interface 2013, 10(84):20130193.
18. Hara H., et al. Role of stent design and coatings on restenosis and thrombosis. Adv. Drug Deliv. Rev. 2006, 58(3):377-386.
19. Lai Y.G. Unstructured grid arbitrarily shaped element method for fluid flow simulation. AIAA J. 2000, 38(12):2246-2252.
20. Issa R.I. Solution of the implicitly discretized fluid-flow equations by operator-splitting. J. Comput. Phys. 1986, 62(1):40-65.
21. Liu X., et al. A volumetric intravascular ultrasound comparison of early drug-eluting stent thrombosis versus restenosis. JACC Cardiovasc. Interv. 2009, 2(5):428-434.
22. Kawaguchi Y., et al. Very late stent thrombosis occurring simultaneously in sirolimus-eluting stents and bare-metal stent in three different coronary vessels. Cardiovasc. Interv. Ther. 2011, 26(1):64-69.
23. Mori D., et al. Computational study on effect of red blood cells on primary thrombus formation. Thromb. Res. 2008, 123(1):114-121.
24. Flamm M.H., Sinno T., Diamond S.L. Simulation of aggregating particles in complex flows by the lattice kinetic Monte Carlo method. J. Chem. Phys. 2011, 134(3). (034905-1-10).
25. Kamada H., et al. A three-dimensional particle simulation of the formation and collapse of a primary thrombus. Int. J. Numer. Methods Biomed. Eng. 2010, 26(3-4):488-500.
26. Kolesnikova I.V., et al. Determination of volume, shape and refractive index of individual blood platelets. J. Quant. Spectrosc. Radiat. Transf. 2006, 102(1):37-45.
27. Skalak R., Ozkaya N., Skalak T.C. Biofluid mechanics. Annu. Rev. Fluid Mech. 1989, 21:167-204.
28. Skalak R., Keller S.R., Secomb T.W. Mechanics of blood flow. J. Biomech. Eng. 1981, 103(2):102-115.
29. Di Felice R. The voidage function for fluid-particle interaction systems. Int. J. Multiph. Flow 1994, 20(1):153-159.
30. Chesnutt J.K.W., Han H.C. Tortuosity triggers platelet activation and thrombus formation in microvessels. J. Biomech. Eng. Trans. ASME 2011, 133. (121004-1-11).
31. Chesnutt J.K.W., Han H.C. Platelet size and density affect shear-induced thrombus formation in tortuous arterioles. Phys. Biol. 2013, 10(5):056003.
32. Wurzinger L.J., et al. Platelet and coagulation parameters following millisecond exposure to laminar shear stress. Thromb. Haemost. 1985, 54(2):381-386.
33. Yong A.S., et al. Intracoronary shear-related up-regulation of platelet P-selectin and platelet-monocyte aggregation despite the use of aspirin and clopidogrel. Blood 2011, 117(1):11-20.
34. Alemu Y., Bluestein D. Flow-induced platelet activation and damage accumulation in a mechanical heart valve: numerical studies. Artif. Organs 2007, 31(9):677-688.
35. Sheriff J., et al. Evaluation of shear-induced platelet activation models under constant and dynamic shear stress loading conditions relevant to devices. Ann. Biomed. Eng. 2013, 41(6):1279-1296.
36. Govindarajan V., et al. Two-dimensional FSI simulation of closing dynamics of a tilting disc mechanical heart valve. J. Med. Device 2010, 4(1):11001.
37. Longest P.W., Kleinstreuer C. Particle-hemodynamics modeling of the distal end-to-side femoral bypass: effects of graft caliber and graft-end cut. Med. Eng. Phys. 2003, 25(10):843-858.
38. Casa L.C., Ku D. High shear thrombus formation under pulsatile and steady flow. Cardiovasc. Eng. Technol. 2014, 5(2):154-163.
39. Berry J.L., et al. Experimental and computational flow evaluation of coronary stents. Ann. Biomed. Eng. 2000, 28(4):386-398.
40. Maalej N., Folts J.D. Increased shear stress overcomes the antithrombotic platelet inhibitory effect of aspirin in stenosed dog coronary arteries. Circulation 1996, 93(6):1201-1205.
41. Barrett N.E., et al. Future innovations in anti-platelet therapies. Br. J. Pharmacol. 2008, 154(5):918-939.
42. Zhang Y., et al. Efficacy and safety of triple-antiplatelet therapy after percutaneous coronary intervention: a meta-analysis. Chin. Med. J. (Engl.) 2013, 126(9):1750-1754.
43. Chen Y., et al. Long-term clinical efficacy and safety of adding cilostazol to dual antiplatelet therapy for patients undergoing PCI: a meta-analysis of randomized trials with adjusted indirect comparisons. Curr. Med. Res. Opin. 2014, 30(1):37-49.
44. Zhou H., et al. Triple versus dual antiplatelet therapy for coronary heart disease patients undergoing percutaneous coronary intervention: a meta-analysis. Exp. Ther. Med. 2013, 6(4):1034-1040.
45. Johnson K.L., Kendall K., Roberts A.D. Surface energy and contact of elastic solids. Proc. R. Soc. Lond. Ser. A-Math. Phys. Sci. 1971, 324(1558):301-313.
46. Bell G.I., Dembo M., Bongrand P. Cell adhesion. Competition between nonspecific repulsion and specific bonding. Biophys. J. 1984, 45(6):1051-1064.
47. Bell G.I. Models for the specific adhesion of cells to cells. Science 1978, 200(4342):618-627.
48. Dembo M., et al. The reaction-limited kinetics of membrane-to-surface adhesion and detachment. Proc. R. Soc. Lond. B Biol. Sci. 1988, 234(1274):55-83.
49. Filipovic N., et al. Interactions of blood cell constituents: experimental investigation and computational modeling by discrete particle dynamics algorithm. Microvasc. Res. 2008, 75(2):279-284.