Computational fluid dynamic simulations of image-based stented coronary bifurcation models

Journal of the Royal Society Interface

Volumn 10, Issue 84, 2013, Pages

  Chiastra, Claudio ^a   Morlacchi, Stefano ^a   Gallo, Diego ^b   Morbiducci, Umberto ^b   Cárdenes, Rubén ^c   Larrabide, Ignacio ^c   Migliavacca, Francesco ^a  

^a POLITECNICO DI MILANO   (Italy)

^b POLITECNICO DI TORINO   (Italy)

^c UNIVERSITAT POMPEU FABRA   (Spain)

Author keywords

Computational fluid dynamics; Coronary bifurcation; Helicity; Patient specific model; Stent; Wall shear stress

Indexed keywords

BIFURCATION (MATHEMATICS); BLOOD VESSELS; COMPUTATIONAL FLUID DYNAMICS; DISEASES; HEMODYNAMICS; STENTS; STRUTS;

COMPUTED TOMOGRAPHY ANGIOGRAPHY; CORONARY ANGIOGRAPHY; EXPERIMENTAL TECHNIQUES; HELICITIES; LEFT ANTERIOR DESCENDING; PATIENT-SPECIFIC MODELS; STENT; WALL SHEAR STRESS;

COMPUTER SIMULATION;

ADULT; ANGIOCARDIOGRAPHY; ARTERY WALL; BLOOD FLOW VELOCITY; CASE REPORT; COMPUTATIONAL FLUID DYNAMICS; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CORONARY ARTERY; CORONARY ARTERY BIFURCATION; CORONARY STENT; DRUG ELUTING STENT; FEMALE; FLOW MEASUREMENT; FLOW RATE; HEART HEMODYNAMICS; HUMAN; IMPLANTATION; IN-STENT RESTENOSIS; LEFT ANTERIOR DESCENDING CORONARY ARTERY; ORGAN PERFUSION; REVIEW; SHEAR STRESS; SIMULATION; ARTICLE; AUDIOVISUAL EQUIPMENT; BIOLOGICAL MODEL; BIOLOGY; BIOMECHANICS; COMPUTER SIMULATION; CORONARY BIFURCATION; CORONARY BLOOD VESSEL; HELICITY; HEMODYNAMICS; METHODOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PATIENT-SPECIFIC MODEL; RESTENOSIS; STENT;

COMPUTATIONAL FLUID DYNAMICS; CORONARY BIFURCATION; HELICITY; PATIENT-SPECIFIC MODEL; STENT; WALL SHEAR STRESS;

BIOMECHANICS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; CORONARY ANGIOGRAPHY; CORONARY RESTENOSIS; CORONARY VESSELS; HEMODYNAMICS; HUMANS; MODELS, ANATOMIC; MODELS, CARDIOVASCULAR;

EID: 84878639815     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2013.0193     Document Type: Article

References (55)

1. Steinman DA, Taylor CA. 2005 Flow imaging and computing: large artery hemodynamics. Ann. Biomed. Eng. 33, 1704-1709. (doi:10.1007/s10439-005-8772-2)
2. Murphy EA, Boyle FJ. 2012 Reducing in-stent restenosis through novel stent flow field augmentation. Cardiovasc. Eng. Technol. 3, 353-373. (doi:10.1007/s13239-012-0109-3)
3. Williams AR, Koo B, Gundert TJ, Fitzgerald PJ, LaDisa Jr JF. 2010 Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. J. Appl. Physiol. 109 532-540. (doi:10.1152/japplphysiol.00086. 2010)
4. Morlacchi S, Chiastra C, Gastaldi D, Pennati G, Dubini G, Migliavacca F. 2011 Sequential structural and fluid dynamic numerical simulations of a stented bifurcated coronary artery. J. Biomech. Eng. 133, 121010. (doi:10.1115/1. 4005476)
5. Behan MW et al. 2011 Simple or complex stenting for bifurcation coronary lesions: a patient-level pooled-analysis of the Nordic bifurcation study and the British bifurcation coronary study. Circ. Cardiovasc. Interv. 4, 57-64. (doi:10.1161/CIRCINTERVENTIONS.110.958512)
6. Chiastra C, Morlacchi S, Pereira S, Dubini G, Migliavacca F. 2012 Fluid dynamics of stented coronary bifurcations studied with a hybrid discretization method. Eur. J. Mech. B/Fluids 35, 76-84. (doi:10.1016/j.euromechflu.2012.01. 011)
7. Sgueglia GA, Chevalier B. 2012 Kissing balloon inflation in percutaneous coronary interventions. JACC: Cardiovasc. Interv. 5, 803-811. (doi:10.1016/j.jcin.2012.06.005)
8. Foin N et al. 2012 Kissing balloon or sequential dilation of the side branch and main vessel for provisional stenting of bifurcations. JACC: Cardiovasc. Interv. 5, 47-56. (doi:10.1016/j.jcin.2011.08.019)
9. Gundert TJ, Shadden SC, Williams AR, Koo B, Feinstein JA, LaDisa Jr JF. 2011 Rapid and computationally inexpensive method to virtually implant current and next-generation stents into subject-specific computational fluid dynamics models. Ann. Biomed. Eng. 39, 1423-1436. (doi:10.1007/s10439-010-0238-5)
10. Ellwein LM, Otake H, Gundert TJ, Koo B, Shinke T, Honda Y, Shite J, LaDisa Jr JF. 2011 Optical coherence tomography for patient-specific 3D artery reconstruction and evaluation of wall shear stress in a left circumflex coronary artery. Cardiovasc. Eng. Technol. 2, 212-227. (doi:10.1007/s13239-011-0047-5)
11. Cárdenes R, Díez JL, Larrabide I, Bogunović H, Frangi AF. 2011 3D modeling of coronary artery bifurcations from CTA and conventional coronary angiography. Med. Image Comput. Assist. Interv. 14, 395-402. (doi:10.1007/978-3-642-23626-6-49)
12. Morlacchi S, Colleoni SG, Cardenes R, Chiastra C, Diez JL, Larrabide I, Migliavacca F. In press. Patientspecific simulations of stenting procedures in coronary bifurcations: two clinical cases. Med. Eng. Phys. (doi:10.1016/j. medengphy.2013.01.007)
13. Murphy JB, Boyle FJ. 2010 Predicting neointimal hyperplasia in stented arteries using timedependent computational fluid dynamics: a review. Comput. Biol. Med. 40, 408-418. (doi:10.1016/j.compbiomed.2010.02.005)
14. Kilner PJ, Yang GZ, Mohiaddin RH, Firmin DN, Longmore DB. 1993 Helical and retrograde secondary flow patterns in the aortic arch studied by three-directional magnetic resonance velocity mapping. Circulation 88, 2235-2247. (doi:10.1161/01.CIR.88.5.2235)
15. Morbiducci U, Ponzini R, Rizzo G, Cadioli M, Esposito A, Montevecchi FM, Redaelli A. 2011 Mechanistic insight into the physiological relevance of helical blood flow in the human aorta: an in vivo study. Biomech. Model. Mechanobiol. 10, 339-355. (doi:10.1007/s10237-010-0238-2)
16. Gallo D, Steinman DA, Bijari PB, Morbiducci U. 2012 Helical flow in carotid bifurcation as surrogate marker of exposure to disturbed shear. J. Biomech. 45, 2398-2404. (doi:10.1016/j.jbiomech.2012.07.007)
17. Morbiducci U, Ponzini R, Grigioni M, Redaelli A. 2007 Helical flow as fluid dynamic signature for atherogenesis in aortocoronary bypass. A numeric study. J. Biomech. 40, 519-534. (doi:10.1016/j.jbiomech.2006.02.017)
18. Chan Z, Fan Y, Deng X, Xu Z. 2011 A new way to reduce flow disturbance in endovascular stents: a numerical study. Artif. Organs 35, 392-397. (doi:10.1111/j.1525-1594.2010.01106.x)
19. Zheng T, Wen J, Diang W, Deng X, Fan Y. In press. Numerical investigation of oxygen mass transfer in a helical-type artery bypass graft. Comput. Methods Biomech. Biomed. Eng. (doi:10.1080/10255842.2012.702764)
20. Gradus-Pizlo I, Bigelow B, Mahomed Y, Sawada SG, Rieger K, Feigenbaum H. 2003 Left anterior descending coronary artery wall thickness measured by high-frequency transthoracic and epicardial echocardiography includes adventitia. Am. J. Cardiol. 91, 27-32. (doi:10.1016/S0002-9149(02)02993-4)
21. Gastaldi D, Morlacchi S, Nichetti R, Capelli C, Dubini G, Petrini L, Migliavacca F. 2010 Modelling of the provisional side-branch stenting approach for the treatment of atherosclerotic coronary bifurcations: effects of stent positioning. Biomech. Model Mechanobiol. 9, 551-561. (doi:10.1007/s10237-010- 0196-8)
22. Davies JE et al. 2006 Evidence of dominant backward-propagating suction wave responsible for diastolic coronary filling in humans, attenuated in left ventricular hypertrophy. Circulation 113, 1768-1778. (doi:10.1161/ circulationaha.105.603050)
23. van der Giessen AG, Groen HC, Doriot P, de Feyter PJ, van der Steen AFW, van de Vosse FN, Wentzel JJ, Gijsen FJH. 2011 The influence of boundary conditions on wall shear stress distribution in patients specific coronary trees. J. Biomech. 44, 1089-1095. (doi:10.1016/j.jbiomech.2011.01.036)
24. Doriot PA, Dorsaz PA, Dorsaz L, De Benedetti E, Chatelain P, Delafontaine P. 2000 In-vivo measurements of wall shear stress in human coronary arteries. Coron. Artery Dis. 11, 495-502. (doi:10.1097/00019501-200009000-00008)
25. Seo T, Schachter LG, Barakat AI. 2005 Computational study of fluid mechanical disturbance induced by endovascular stents. Ann. Biomed. Eng. 33, 444-456. (doi:10.1007/s10439-005-2499-y)
26. Malek AM, Alper SL, Izumo S. 1999 Hemodynamic shear stress and its role in atherosclerosis. J. Am. Med. Assoc. 282, 2035-2042. (doi:10.1001/jama.282.21. 2035)
27. LaDisa Jr JF, Olson LE, Molthen RC, Hettrick DA, Pratt PF, Hardel MD, Kersten JR, Warltier DC, Pagel PS. 2005 Alterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries. Am. J. Physiol. Heart. Circ. Physiol. 288, H2465-H2475. (doi:10.1152/ajpheart.01107.2004)
28. Zarins CK, Giddens DP, Bharadvaj BK, Sottiurai VS, Mabon RF, Glagov S. 1983 Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ. Res. 53, 502-514. (Pubitemid 14231103)
29. Himburg HA, Grzybowski DM, Hazel AL, LaMack JA, Li XM, Friedman MH. 2004 Spatial comparison between wall shear stress measures and porcine arterial endothelial permeability. Am. J. Physiol. Heart Circ. Physiol. 286, H1916-H1922. (doi:10.1152/ajpheart.00897.2003)
30. Malek AM, Izumo S. 1992 Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium. Am. J. Physiol. Cell Physiol. 263, C389-C396.
31. Chiu JJ, Chien S. 2011 Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol. Rev. 91, 327-387. (doi:10.1152/physrev.00047.2009)
32. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. 2007 Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll. Cardiol. 49, 2379-2393. (Pubitemid 46962266)
33. Yin W, Shanmugavelayudam SK, Rubenstein DA. 2011 The effect of physiologically relevant dynamic shear stress on platelet and endothelial cell activation. Thromb. Res. 127, 235-241. (doi:10.1016/j.thromres.2010.11.021)
34. Dardik A, Chen L, Frattini J, Asada H, Aziz F, Kudo FA, Sumpio BE. 2005 Differential effects of orbital and laminar shear stress on endothelial cells. J. Vasc. Surg. 41, 869-880. (doi:10.1016/j.jvs.2005.01.020)
35. Dai G, Kaazempur-Mofrad MR, Natarajan S, Zhang Y, Vaughn S, Blackman BR, Kamm RD, García-Cardeña G, Gimbrone Jr MA. 2004 Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proc. Natl Acad. Sci. USA 101, 14 871-14 876. (doi:10.1073/pnas.0406073101)
36. Hoi Y, Zhou Y, Zhang X, Henkelman X, Steinman DA. 2011 Correlation between local hemodynamics and lesion distribution in a novel aortic regurgitation murine model of atherosclerosis. Ann. Biomed. Eng. 39, 1414-1422. (doi:10.1007/s10439-011-0255-z)
37. Massai D, Soloperto G, Gallo D, Xu XY, Morbiducci U. 2012 Shear-induced platelet activation and its relationship with blood flow topology in a numerical model of stenosed carotid bifurcation. Eur. J. Mech. B Fluids 35, 92-101. (doi:10.1016/j.euromechflu.2012.03.011)
38. Moffatt HK, Tsinober A. 1992 Helicity in laminar and turbulent flow. Annu. Rev. Fluid Mech. 24, 281-312. (doi:10.1146/annurev.fl.24.010192.001433)
39. Murphy JB, Boyle FJ. 2010 A numerical methodology to fully elucidate the altered wall shear stress in a stented coronary artery. Cardiovasc. Eng. Technol. 1, 256-268. (doi:10.1007/s13239-10-0028-0)
40. Frazin LJ, Vonesh MJ, Chandran KB, Shipkowitz T, Yaacoub AS, McPherson DD. 1996 Confirmation and initial documentation of thoracic and abdominal aortic helical flow. An ultrasound study. ASAIO J. 42, 951-956. (Pubitemid 26415139)
41. Wentzel JJ, Gijsen FJH, Schuurbiers JCH, van der Steen AFW, Serruys PW. 2008 The influence of shear stress on in-stent restenosis and thrombosis. EuroIntervention 4(Suppl. C), C27-C32.
42. Gundert TJ, Dholakia RJ, McMahon D, LaDisa Jr JF. 2013 Computational fluid dynamics evaluation of equivalency in hemodynamic alterations between Driver, Integrity, and similar stents implanted into an idealized coronary artery. J. Med. Devices 7, 011004. (doi:10.1115/1.4023413)
43. Balossino R, Gervaso F, Migliavacca F, Dubini G. 2008 Effects of different stent designs on local hemodynamics in stented arteries. J. Biomech. 41, 1053-1061. (doi:10.1016/j.jbiomech.2007.12.005)
44. Asakura T, Karino T. 1990 Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries. Circ Res. 66, 1045-1066. (doi:10.1161/01.RES.66.4.1045)
45. Ku DN. 1997 Blood flow in arteries. Annu. Rev. Fluid Mech. 29, 399-434. (doi:10.1146/annurev. fluid.29.1.399)
46. Liu X, Fan Y, Deng X. 2009 Effect of spiral flow on the transport of oxygen in the aorta: a numerical study. Ann. Biomed. Eng. 38, 917-926. (doi:10. 1007/s10439-009-9878-8)
47. Lantz J, Karlsson M. 2012 Large eddy simulation of LDL surface concentration in a subject specific human aorta. J. Biomech. 45, 537-542. (doi:10.1016/j.jbiomech.2011.11.039)
48. Sun A, Fan Y, Deng X. 2012 Intentionally induced swirling flow may improve the hemodynamic performance of coronary bifurcation stenting. Catheter. Cardiovasc. Interv. 79, 371-377. (doi:10.1002/ccd.22969)
49. Kolachalama VB, Levine EG, Edelman ER. 2009 Luminal flow amplifies stent-based drug deposition in arterial bifurcations. PLoS ONE 4, e8105 (doi:10.1371/journal.pone.0008105.s001)
50. D'Angelo C, Zunino P, Porpora A, Morlacchi S, Migliavacca F. 2011 Model reduction strategies enable computational analysis of controlled drug release from cardiovascular stents. SIAM J. Appl. Math. 71, 2312-2333. (doi:10.1137/10081695X)
51. Cutrí E, Zunino P, Morlacchi S, Chiastra C, Migliavacca F. In press. Drug delivery patterns for different stenting techniques in coronary bifurcations: a comparative computational study. Biomech. Model Mechanobiol. (doi:10.1007/s10237-012-0432-5)
52. Arbab-Zadeh A, Texter J, Ostbye K. 2010 Quantification of lumen stenosis with known dimensions by conventional angiography and CT: implications for the use of angiography as a gold standard. Heart 9, 1358-1363. (doi:10.1136/hrt. 2009.186783)
53. Malvè M, Garcia A, Ohayon J, Martinez MA. 2012 Unsteady blood flow and mass transfer of a human left coronary artery bifurcation: FSI versus CFD. Int. Commun. Heat Mass 39, 745-751. (doi:10.1016/j.icheatmasstransfer.2012.04. 009)
54. Theodorakakos A, Gavaises M, Andriotis A, Zifan A, Liatsis P, Pantos I, Efstathopoulos EP, Katritsis D. 2008 Simulation of cardiac motion on non-Newtonian, pulsating flow development in the human left anterior descending coronary artery. Phys. Med. Biol. 53, 4875-4892. (doi:10.1088/0031-9155/53/18/ 002)
55. Zeng D, Ding Z, Friedman MH, Ethier CR. 2003 Effects of cardiac motion on right coronary artery hemodynamics. Ann. Biomed. Eng. 31, 420-429.