Fabrication of functional 3D hepatic tissues with polarized hepatocytes by stacking endothelial cell sheets in vitro

Journal of Tissue Engineering and Regenerative Medicine

Volumn 11, Issue 7, 2017, Pages 2071-2080

  Kim, Kyungsook ^a,b   Utoh, Rie ^a   Ohashi, Kazuo ^a,c   Kikuchi, Tetsutaro ^a   Okano, Teruo ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b Ajou University   (South Korea)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

3D tissue; cell sheet; cell cell interaction; co culture system; hepatic function; hepatocyte polarity

Indexed keywords

ARTIFICIAL ORGANS; COPYRIGHTS; CYTOLOGY; FABRICATION; HISTOLOGY; TISSUE; TISSUE ENGINEERING; TRANSMISSION ELECTRON MICROSCOPY;

3D TISSUES; CELL SHEET; CELL-CELL INTERACTION; CO-CULTURE SYSTEM; ENDOTHELIAL-CELLS; HEPATIC FUNCTION; HEPATIC TISSUE; HEPATOCYTE POLARITY; HEPATOCYTES; IN-VITRO;

ENDOTHELIAL CELLS;

ALBUMIN; CD147 ANTIGEN; CLAUDIN 3; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 3A; GELATIN; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2;

ADHESION; ANIMAL CELL; ARTICLE; BASOLATERAL MEMBRANE; CELL ADHESION; CELL CULTURE TECHNIQUE; CELL MEMBRANE; CELL POLARITY; CELLULAR DISTRIBUTION; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GEL; HYDROGEL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIVER CELL; LIVER STRUCTURE; LIVER TISSUE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; THICKNESS; ANIMAL; CYTOLOGY; ENDOTHELIUM; FISCHER 344 RAT; LIVER; MALE; METABOLISM; PROCEDURES; TISSUE ENGINEERING;

ANIMALS; ENDOTHELIUM; HEPATOCYTES; LIVER; MALE; RATS; RATS, INBRED F344; TISSUE ENGINEERING;

EID: 84949034717     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.2102     Document Type: Article

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