메뉴 건너뛰기




Volumn 126, Issue 21, 2015, Pages 2404-2414

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NANOTUBE; PREDNISOLONE; TUNNELING NANOTUBE; UNCLASSIFIED DRUG;

EID: 84949034427     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-03-634238     Document Type: Article
Times cited : (146)

References (58)
  • 1
    • 57849108116 scopus 로고    scopus 로고
    • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
    • Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science. 2008;322(5909):1861-1865.
    • (2008) Science , vol.322 , Issue.5909 , pp. 1861-1865
    • Colmone, A.1    Amorim, M.2    Pontier, A.L.3    Wang, S.4    Jablonski, E.5    Sipkins, D.A.6
  • 2
    • 33947574961 scopus 로고    scopus 로고
    • Donor cell leukemia: Insight into cancer stem cells and the stem cell niche
    • Flynn CM, Kaufman DS. Donor cell leukemia: insight into cancer stem cells and the stem cell niche. Blood. 2007;109(7):2688-2692.
    • (2007) Blood , vol.109 , Issue.7 , pp. 2688-2692
    • Flynn, C.M.1    Kaufman, D.S.2
  • 3
    • 77950862042 scopus 로고    scopus 로고
    • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
    • Raaijmakers MH, Mukherjee S, Guo S, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 2010; 464(7290):852-857.
    • (2010) Nature , vol.464 , Issue.7290 , pp. 852-857
    • Raaijmakers, M.H.1    Mukherjee, S.2    Guo, S.3
  • 4
    • 34250331610 scopus 로고    scopus 로고
    • A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency
    • Walkley CR, Olsen GH, Dworkin S, et al. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell. 2007;129(6):1097-1110.
    • (2007) Cell , vol.129 , Issue.6 , pp. 1097-1110
    • Walkley, C.R.1    Olsen, G.H.2    Dworkin, S.3
  • 5
    • 34250363611 scopus 로고    scopus 로고
    • Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment
    • Walkley CR, Shea JM, Sims NA, Purton LE, Orkin SH. Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. Cell. 2007;129(6):1081-1095.
    • (2007) Cell , vol.129 , Issue.6 , pp. 1081-1095
    • Walkley, C.R.1    Shea, J.M.2    Sims, N.A.3    Purton, L.E.4    Orkin, S.H.5
  • 6
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • Yilmaz OH, Valdez R, Theisen BK, et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. 2006; 441(7092):475-482.
    • (2006) Nature , vol.441 , Issue.7092 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3
  • 7
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/ angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • Arai F, Hirao A, Ohmura M, et al. Tie2/ angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell. 2004;118(2):149-161.
    • (2004) Cell , vol.118 , Issue.2 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3
  • 8
    • 79958279325 scopus 로고    scopus 로고
    • In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
    • Fujisaki J, Wu J, Carlson AL, et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 2011; 474(7350):216-219.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 216-219
    • Fujisaki, J.1    Wu, J.2    Carlson, A.L.3
  • 9
    • 77950542260 scopus 로고    scopus 로고
    • Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity
    • McMillin DW, Delmore J, Weisberg E, et al. Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity. Nat Med. 2010;16(4):483-489.
    • (2010) Nat Med , vol.16 , Issue.4 , pp. 483-489
    • McMillin, D.W.1    Delmore, J.2    Weisberg, E.3
  • 10
    • 84859820567 scopus 로고    scopus 로고
    • Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance
    • Nakasone ES, Askautrud HA, Kees T, et al. Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell. 2012;21(4):488-503.
    • (2012) Cancer Cell , vol.21 , Issue.4 , pp. 488-503
    • Nakasone, E.S.1    Askautrud, H.A.2    Kees, T.3
  • 11
    • 33749515476 scopus 로고    scopus 로고
    • Targeting of CD44 eradicates human acute myeloid leukemic stem cells
    • Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med. 2006; 12(10):1167-1174.
    • (2006) Nat Med , vol.12 , Issue.10 , pp. 1167-1174
    • Jin, L.1    Hope, K.J.2    Zhai, Q.3    Smadja-Joffe, F.4    Dick, J.E.5
  • 12
    • 0141461414 scopus 로고    scopus 로고
    • Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
    • Matsunaga T, Takemoto N, Sato T, et al. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia. Nat Med. 2003;9(9):1158-1165.
    • (2003) Nat Med , vol.9 , Issue.9 , pp. 1158-1165
    • Matsunaga, T.1    Takemoto, N.2    Sato, T.3
  • 13
    • 67650410440 scopus 로고    scopus 로고
    • Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
    • Nervi B, Ramirez P, Rettig MP, et al. Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. Blood. 2009;113(24):6206-6214.
    • (2009) Blood , vol.113 , Issue.24 , pp. 6206-6214
    • Nervi, B.1    Ramirez, P.2    Rettig, M.P.3
  • 15
    • 13744255245 scopus 로고    scopus 로고
    • CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice
    • Tavor S, Petit I, Porozov S, et al. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. Cancer Res. 2004; 64(8):2817-2824.
    • (2004) Cancer Res , vol.64 , Issue.8 , pp. 2817-2824
    • Tavor, S.1    Petit, I.2    Porozov, S.3
  • 16
    • 67650367598 scopus 로고    scopus 로고
    • Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML
    • Zeng Z, Shi YX, Samudio IJ, et al. Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML. Blood. 2009;113(24):6215-6224.
    • (2009) Blood , vol.113 , Issue.24 , pp. 6215-6224
    • Zeng, Z.1    Shi, Y.X.2    Samudio, I.J.3
  • 17
    • 77950398569 scopus 로고    scopus 로고
    • Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells
    • Chauveau A, Aucher A, Eissmann P, Vivier E, Davis DM. Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells. Proc Natl Acad Sci USA. 2010;107(12):5545-5550.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.12 , pp. 5545-5550
    • Chauveau, A.1    Aucher, A.2    Eissmann, P.3    Vivier, E.4    Davis, D.M.5
  • 18
    • 3242767507 scopus 로고    scopus 로고
    • Cutting edge: Membrane nanotubes connect immune cells
    • Onfelt B, Nedvetzki S, Yanagi K, Davis DM. Cutting edge: Membrane nanotubes connect immune cells. J Immunol. 2004;173(3):1511-1513.
    • (2004) J Immunol , vol.173 , Issue.3 , pp. 1511-1513
    • Onfelt, B.1    Nedvetzki, S.2    Yanagi, K.3    Davis, D.M.4
  • 19
    • 84881041895 scopus 로고    scopus 로고
    • H-Ras transfers from B to T cells via tunneling nanotubes
    • Rainy N, Chetrit D, Rouger V, et al. H-Ras transfers from B to T cells via tunneling nanotubes. Cell Death Dis. 2013;4: e726.
    • (2013) Cell Death Dis , vol.4
    • Rainy, N.1    Chetrit, D.2    Rouger, V.3
  • 20
    • 1142286348 scopus 로고    scopus 로고
    • Nanotubular highways for intercellular organelle transport
    • Rustom A, Saffrich R, Markovic I, Walther P, Gerdes HH. Nanotubular highways for intercellular organelle transport. Science. 2004; 303(5660):1007-1010.
    • (2004) Science , vol.303 , Issue.5660 , pp. 1007-1010
    • Rustom, A.1    Saffrich, R.2    Markovic, I.3    Walther, P.4    Gerdes, H.H.5
  • 21
    • 38849168755 scopus 로고    scopus 로고
    • Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission
    • Sowinski S, Jolly C, Berninghausen O, et al. Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. Nat Cell Biol. 2008;10(2):211-219.
    • (2008) Nat Cell Biol , vol.10 , Issue.2 , pp. 211-219
    • Sowinski, S.1    Jolly, C.2    Berninghausen, O.3
  • 22
    • 24944582967 scopus 로고    scopus 로고
    • Functional connectivity between immune cells mediated by tunneling nanotubules
    • Watkins SC, Salter RD. Functional connectivity between immune cells mediated by tunneling nanotubules. Immunity. 2005;23(3):309-318.
    • (2005) Immunity , vol.23 , Issue.3 , pp. 309-318
    • Watkins, S.C.1    Salter, R.D.2
  • 23
    • 73849142314 scopus 로고    scopus 로고
    • Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes
    • Arkwright PD, Luchetti F, Tour J, et al. Fas stimulation of T lymphocytes promotes rapid intercellular exchange of death signals via membrane nanotubes. Cell Res. 2010;20(1):72-88.
    • (2010) Cell Res , vol.20 , Issue.1 , pp. 72-88
    • Arkwright, P.D.1    Luchetti, F.2    Tour, J.3
  • 24
    • 84857746017 scopus 로고    scopus 로고
    • Different modalities of intercellular membrane exchanges mediate cell-to-cell p-glycoprotein transfers in MCF-7 breast cancer cells
    • Pasquier J, Galas L, Boulangé-Lecomte C, et al. Different modalities of intercellular membrane exchanges mediate cell-to-cell p-glycoprotein transfers in MCF-7 breast cancer cells. J Biol Chem. 2012;287(10):7374-7387.
    • (2012) J Biol Chem , vol.287 , Issue.10 , pp. 7374-7387
    • Pasquier, J.1    Galas, L.2    Boulangé-Lecomte, C.3
  • 25
    • 44449108230 scopus 로고    scopus 로고
    • Cutting edge: Membrane nanotubes in vivo: A feature of MHC class II1 cells in the mouse cornea
    • Chinnery HR, Pearlman E, McMenamin PG. Cutting edge: Membrane nanotubes in vivo: a feature of MHC class II1 cells in the mouse cornea. J Immunol. 2008;180(9):5779-5783.
    • (2008) J Immunol , vol.180 , Issue.9 , pp. 5779-5783
    • Chinnery, H.R.1    Pearlman, E.2    McMenamin, P.G.3
  • 26
    • 84866327994 scopus 로고    scopus 로고
    • Multifaceted roles of tunneling nanotubes in intercellular communication
    • Marzo L, Gousset K, Zurzolo C. Multifaceted roles of tunneling nanotubes in intercellular communication. Front Physiol. 2012;3:72.
    • (2012) Front Physiol , vol.3 , pp. 72
    • Marzo, L.1    Gousset, K.2    Zurzolo, C.3
  • 27
    • 84872137228 scopus 로고    scopus 로고
    • Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction
    • Seyed-Razavi Y, Hickey MJ, Kuffová L, McMenamin PG, Chinnery HR. Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction. Immunol Cell Biol. 2013;91(1):89-95.
    • (2013) Immunol Cell Biol , vol.91 , Issue.1 , pp. 89-95
    • Seyed-Razavi, Y.1    Hickey, M.J.2    Kuffová, L.3    McMenamin, P.G.4    Chinnery, H.R.5
  • 28
    • 84875932682 scopus 로고    scopus 로고
    • Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance
    • Pasquier J, Guerrouahen BS, Al Thawadi H, et al. Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance. J Transl Med. 2013;11:94.
    • (2013) J Transl Med , vol.11 , pp. 94
    • Pasquier, J.1    Guerrouahen, B.S.2    Al Thawadi, H.3
  • 29
    • 84857926403 scopus 로고    scopus 로고
    • Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma
    • Lou E, Fujisawa S, Morozov A, et al. Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma. PLoS One. 2012;7(3): e33093.
    • (2012) PLoS One , vol.7 , Issue.3
    • Lou, E.1    Fujisawa, S.2    Morozov, A.3
  • 30
    • 61849178720 scopus 로고    scopus 로고
    • Prions hijack tunnelling nanotubes for intercellular spread
    • Gousset K, SchiffE, Langevin C, et al. Prions hijack tunnelling nanotubes for intercellular spread. Nat Cell Biol. 2009;11(3):328-336.
    • (2009) Nat Cell Biol , vol.11 , Issue.3 , pp. 328-336
    • Gousset, K.1    Schiff, E.2    Langevin, C.3
  • 31
    • 0141799965 scopus 로고    scopus 로고
    • Patient stratification based on prednisolone-vincristineasparaginase resistance profiles in children with acute lymphoblastic leukemia
    • Den Boer ML, Harms DO, Pieters R, et al. Patient stratification based on prednisolone-vincristineasparaginase resistance profiles in children with acute lymphoblastic leukemia. J Clin Oncol. 2003; 21(17):3262-3268.
    • (2003) J Clin Oncol , vol.21 , Issue.17 , pp. 3262-3268
    • Den Boer, M.L.1    Harms, D.O.2    Pieters, R.3
  • 32
    • 84903697068 scopus 로고    scopus 로고
    • Disturbed CXCR4/CXCL12 axis in paediatric precursor B-cell acute lymphoblastic leukaemia
    • van den Berk LC, van der Veer A, Willemse ME, et al. Disturbed CXCR4/CXCL12 axis in paediatric precursor B-cell acute lymphoblastic leukaemia. Br J Haematol. 2014;166(2):240-249.
    • (2014) Br J Haematol , vol.166 , Issue.2 , pp. 240-249
    • Van Den Berk, L.C.1    Van Der Veer, A.2    Willemse, M.E.3
  • 33
    • 78651502971 scopus 로고    scopus 로고
    • Optimized methods for imaging membrane nanotubes between T cells and trafficking of HIV-1
    • Sowinski S, Alakoskela JM, Jolly C, Davis DM. Optimized methods for imaging membrane nanotubes between T cells and trafficking of HIV-1. Methods. 2011;53(1):27-33.
    • (2011) Methods , vol.53 , Issue.1 , pp. 27-33
    • Sowinski, S.1    Alakoskela, J.M.2    Jolly, C.3    Davis, D.M.4
  • 34
    • 84862520770 scopus 로고    scopus 로고
    • Fiji: An open-source platform for biological-image analysis
    • Schindelin J, Arganda-Carreras I, Frise E, et al. Fiji: an open-source platform for biological-image analysis. Nat Methods. 2012;9(7):676-682.
    • (2012) Nat Methods , vol.9 , Issue.7 , pp. 676-682
    • Schindelin, J.1    Arganda-Carreras, I.2    Frise, E.3
  • 35
    • 33846036832 scopus 로고    scopus 로고
    • Inefficient human immunodeficiency virus replication in mobile lymphocytes
    • Sourisseau M, Sol-Foulon N, Porrot F, Blanchet F, Schwartz O. Inefficient human immunodeficiency virus replication in mobile lymphocytes. J Virol. 2007;81(2):1000-1012.
    • (2007) J Virol , vol.81 , Issue.2 , pp. 1000-1012
    • Sourisseau, M.1    Sol-Foulon, N.2    Porrot, F.3    Blanchet, F.4    Schwartz, O.5
  • 36
    • 79960944057 scopus 로고    scopus 로고
    • Membrane vesicles, current state-of-the-art: Emerging role of extracellular vesicles
    • György B, Szabó TG, Pásztói M, et al. Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles. Cell Mol Life Sci. 2011; 68(16):2667-2688.
    • (2011) Cell Mol Life Sci , vol.68 , Issue.16 , pp. 2667-2688
    • György, B.1    Szabó, T.G.2    Pásztói, M.3
  • 37
    • 58149260269 scopus 로고    scopus 로고
    • Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
    • Lo Celso C, Fleming HE, Wu JW, et al. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 2009;457(7225):92-96.
    • (2009) Nature , vol.457 , Issue.7225 , pp. 92-96
    • Lo Celso, C.1    Fleming, H.E.2    Wu, J.W.3
  • 38
    • 33846246384 scopus 로고    scopus 로고
    • Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells
    • Alon R, Dustin ML. Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. Immunity. 2007;26(1):17-27.
    • (2007) Immunity , vol.26 , Issue.1 , pp. 17-27
    • Alon, R.1    Dustin, M.L.2
  • 39
    • 50849132538 scopus 로고    scopus 로고
    • Cells on the run: Shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells
    • Alon R, Ley K. Cells on the run: shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells. Curr Opin Cell Biol. 2008; 20(5):525-532.
    • (2008) Curr Opin Cell Biol , vol.20 , Issue.5 , pp. 525-532
    • Alon, R.1    Ley, K.2
  • 40
    • 84865483514 scopus 로고    scopus 로고
    • The antitumour activities induced by pegylated liposomal cytochalasin D in murine models
    • Huang FY, Mei WL, Li YN, et al. The antitumour activities induced by pegylated liposomal cytochalasin D in murine models. Eur J Cancer. 2012;48(14):2260-2269.
    • (2012) Eur J Cancer , vol.48 , Issue.14 , pp. 2260-2269
    • Huang, F.Y.1    Mei, W.L.2    Li, Y.N.3
  • 41
    • 30744432663 scopus 로고    scopus 로고
    • Effects of cytochalasin D-eluting stents on intimal hyperplasia in a porcine coronary artery model
    • Salu KJ, Bosmans JM, Huang Y, et al. Effects of cytochalasin D-eluting stents on intimal hyperplasia in a porcine coronary artery model. Cardiovasc Res. 2006;69(2):536-544.
    • (2006) Cardiovasc Res , vol.69 , Issue.2 , pp. 536-544
    • Salu, K.J.1    Bosmans, J.M.2    Huang, Y.3
  • 43
    • 0023637601 scopus 로고
    • New perspectives in cell adhesion: RGD and integrins
    • Ruoslahti E, Pierschbacher MD. New perspectives in cell adhesion: RGD and integrins. Science. 1987;238(4826):491-497.
    • (1987) Science , vol.238 , Issue.4826 , pp. 491-497
    • Ruoslahti, E.1    Pierschbacher, M.D.2
  • 44
    • 84864285794 scopus 로고    scopus 로고
    • Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
    • Straussman R, Morikawa T, Shee K, et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature. 2012;487(7408):500-504.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 500-504
    • Straussman, R.1    Morikawa, T.2    Shee, K.3
  • 45
    • 84864286442 scopus 로고    scopus 로고
    • Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
    • Wilson TR, Fridlyand J, Yan Y, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012; 487(7408):505-509.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 505-509
    • Wilson, T.R.1    Fridlyand, J.2    Yan, Y.3
  • 46
    • 84875174768 scopus 로고    scopus 로고
    • The role of tumour-stromal interactions in modifying drug response: Challenges and opportunities
    • McMillin DW, Negri JM, Mitsiades CS. The role of tumour-stromal interactions in modifying drug response: challenges and opportunities. Nat Rev Drug Discov. 2013;12(3):217-228.
    • (2013) Nat Rev Drug Discov , vol.12 , Issue.3 , pp. 217-228
    • McMillin, D.W.1    Negri, J.M.2    Mitsiades, C.S.3
  • 47
    • 84902200836 scopus 로고    scopus 로고
    • Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit
    • Medyouf H, Mossner M, Jann JC, et al. Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit. Cell Stem Cell. 2014;14(6):824-837.
    • (2014) Cell Stem Cell , vol.14 , Issue.6 , pp. 824-837
    • Medyouf, H.1    Mossner, M.2    Jann, J.C.3
  • 48
    • 84884164883 scopus 로고    scopus 로고
    • Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a selfreinforcing leukemic niche
    • Schepers K, Pietras EM, Reynaud D, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a selfreinforcing leukemic niche. Cell Stem Cell. 2013; 13(3):285-299.
    • (2013) Cell Stem Cell , vol.13 , Issue.3 , pp. 285-299
    • Schepers, K.1    Pietras, E.M.2    Reynaud, D.3
  • 49
    • 84859832491 scopus 로고    scopus 로고
    • Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia
    • Zhang B, Ho YW, Huang Q, et al. Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia. Cancer Cell. 2012;21(4):577-592.
    • (2012) Cancer Cell , vol.21 , Issue.4 , pp. 577-592
    • Zhang, B.1    Ho, Y.W.2    Huang, Q.3
  • 50
    • 79952092993 scopus 로고    scopus 로고
    • Leukemia stem cells and microenvironment: Biology and therapeutic targeting
    • Konopleva MY, Jordan CT. Leukemia stem cells and microenvironment: biology and therapeutic targeting. J Clin Oncol. 2011;29(5):591-599.
    • (2011) J Clin Oncol , vol.29 , Issue.5 , pp. 591-599
    • Konopleva, M.Y.1    Jordan, C.T.2
  • 51
    • 84893502903 scopus 로고    scopus 로고
    • Sensitizing protective tumor microenvironments to antibodymediated therapy
    • Pallasch CP, Leskov I, Braun CJ, et al. Sensitizing protective tumor microenvironments to antibodymediated therapy. Cell. 2014;156(3):590-602.
    • (2014) Cell , vol.156 , Issue.3 , pp. 590-602
    • Pallasch, C.P.1    Leskov, I.2    Braun, C.J.3
  • 52
    • 79957923046 scopus 로고    scopus 로고
    • Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor
    • Manshouri T, Estrov Z, Quintás-Cardama A, et al. Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor. Cancer Res. 2011;71(11):3831-3840.
    • (2011) Cancer Res , vol.71 , Issue.11 , pp. 3831-3840
    • Manshouri, T.1    Estrov, Z.2    Quintás-Cardama, A.3
  • 53
    • 84885099905 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Sensors and switchers of inflammation
    • Bernardo ME, Fibbe WE. Mesenchymal stromal cells: sensors and switchers of inflammation. Cell Stem Cell. 2013;13(4):392-402.
    • (2013) Cell Stem Cell , vol.13 , Issue.4 , pp. 392-402
    • Bernardo, M.E.1    Fibbe, W.E.2
  • 54
    • 0029930173 scopus 로고    scopus 로고
    • Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonging survival in an autocrine fashion
    • Francia di Celle P, Mariani S, Riera L, Stacchini A, Reato G, Foa R. Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonging survival in an autocrine fashion. Blood. 1996;87(10):4382-4389.
    • (1996) Blood , vol.87 , Issue.10 , pp. 4382-4389
    • Francia di Celle, P.1    Mariani, S.2    Riera, L.3    Stacchini, A.4    Reato, G.5    Foa, R.6
  • 55
    • 84865763578 scopus 로고    scopus 로고
    • CCL2 and CXCL2 enhance survival of primary chronic lymphocytic leukemia cells in vitro
    • Burgess M, Cheung C, Chambers L, et al. CCL2 and CXCL2 enhance survival of primary chronic lymphocytic leukemia cells in vitro. Leuk Lymphoma. 2012;53(10):1988-1998.
    • (2012) Leuk Lymphoma , vol.53 , Issue.10 , pp. 1988-1998
    • Burgess, M.1    Cheung, C.2    Chambers, L.3
  • 56
    • 84856013431 scopus 로고    scopus 로고
    • Clonal evolution in cancer
    • Greaves M, Maley CC. Clonal evolution in cancer. Nature. 2012;481(7381):306-313.
    • (2012) Nature , vol.481 , Issue.7381 , pp. 306-313
    • Greaves, M.1    Maley, C.C.2
  • 57
    • 84896070368 scopus 로고    scopus 로고
    • Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation
    • Blackburn JS, Liu S, Wilder JL, et al. Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activation. Cancer Cell. 2014;25(3):366-378.
    • (2014) Cancer Cell , vol.25 , Issue.3 , pp. 366-378
    • Blackburn, J.S.1    Liu, S.2    Wilder, J.L.3
  • 58
    • 84930179795 scopus 로고    scopus 로고
    • Genomics in acute lymphoblastic leukaemia: Insights and treatment implications
    • Roberts KG, Mullighan CG. Genomics in acute lymphoblastic leukaemia: insights and treatment implications. Nat Rev Clin Oncol. 2015;12(6):344-357.
    • (2015) Nat Rev Clin Oncol , vol.12 , Issue.6 , pp. 344-357
    • Roberts, K.G.1    Mullighan, C.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.