Essential role of the EF-hand domain in targeting sperm phospholipase Cζ to membrane phosphatidylinositol 4,5-bisphosphate (PIP2)

Journal of Biological Chemistry

Volumn 290, Issue 49, 2015, Pages 29519-29530

  Nomikos, Michail ^a   Sanders, Jessica R ^a   Parthimos, Dimitris ^a   Buntwal, Luke ^a   Calver, Brian L ^a   Stamatiadis, Panagiotis ^a   Smith, Adrian ^a   Clue, Matthew ^a   Sideratou, Zili ^b   Swann, Karl ^a   Lai, F Anthony ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINS; MAMMALS; PHOSPHOLIPIDS;

ANIONIC PHOSPHOLIPIDS; PHOSPHATIDYLINOSITOL 4 ,5-BISPHOSPHATE; PHOSPHATIDYLSERINE; PLECKSTRIN HOMOLOGY DOMAINS; POSITIVELY CHARGED; POTENTIAL MECHANISM; SEQUENTIAL REDUCTIONS; SPERM-SPECIFIC PHOSPHOLIPASE;

CALCIUM;

LIPOSOME; MUTANT PROTEIN; PHOSPHATIDIC ACID; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLSERINE; PHOSPHOLIPASE C DELTA; CALCIUM; CATION; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PLCZ1 PROTEIN, MOUSE; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; EF HAND DOMAIN; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SPERM; ANIMAL; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; ENZYMOLOGY; FEMALE; HYDROLYSIS; MALE; METABOLISM; MUTATION; OOCYTE; PLASMID; SPERMATOZOON; THEORETICAL MODEL;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CATIONS; CELL MEMBRANE; EF HAND MOTIFS; FEMALE; HYDROLYSIS; LIPOSOMES; MALE; MICE; MODELS, THEORETICAL; MUTATION; OOCYTES; PHOSPHATIDIC ACIDS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHATIDYLSERINES; PHOSPHOINOSITIDE PHOSPHOLIPASE C; PLASMIDS; PROTEIN BINDING; SPERMATOZOA;

EID: 84949033253     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.658443     Document Type: Article

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