-
1
-
-
84870206736
-
Function of members of the neuropilin family as essential pleiotropic cell surface receptors
-
Parker, M. W., Guo, H. F., Li, X., Linkugel, A. D., and Vander Kooi, C. W. (2012) Function of members of the neuropilin family as essential pleiotropic cell surface receptors. Biochemistry 51, 9437-9446
-
(2012)
Biochemistry
, vol.51
, pp. 9437-9446
-
-
Parker, M.W.1
Guo, H.F.2
Li, X.3
Linkugel, A.D.4
Vander Kooi, W.C.5
-
2
-
-
0032707249
-
A requirement for neuropilin-1 in embryonic vessel formation
-
Kawasaki, T., Kitsukawa, T., Bekku, Y., Matsuda, Y., Sanbo, M., Yagi, T., and Fujisawa, H. (1999) A requirement for neuropilin-1 in embryonic vessel formation. Development 126, 4895-4902
-
(1999)
Development
, vol.126
, pp. 4895-4902
-
-
Kawasaki, T.1
Kitsukawa, T.2
Bekku, Y.3
Matsuda, Y.4
Sanbo, M.5
Yagi, T.6
Fujisawa, H.7
-
3
-
-
0029562097
-
Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs
-
Kitsukawa, T., Shimono, A., Kawakami, A., Kondoh, H., and Fujisawa, H. (1995) Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development 121, 4309-4318
-
(1995)
Development
, vol.121
, pp. 4309-4318
-
-
Kitsukawa, T.1
Shimono, A.2
Kawakami, A.3
Kondoh, H.4
Fujisawa, H.5
-
4
-
-
84900412270
-
Control of cellular motility by neuropilin-mediated physical interactions
-
Li, X., Parker, M. W., and Vander Kooi, C. W. (2014) Control of cellular motility by neuropilin-mediated physical interactions. Biomol. Concepts 5, 157-166
-
(2014)
Biomol. Concepts
, vol.5
, pp. 157-166
-
-
Li, X.1
Parker, M.W.2
Vander Kooi, W.C.3
-
5
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., Declercq, C., Pawling, J., Moons, L., Collen, D., Risau, W., and Nagy, A. (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380, 435-439
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
6
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., O'Shea, K. S., Powell-Braxton, L., Hillan, K. J., and Moore, M. W. (1996) Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380, 439-442
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O'Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
7
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L., and Schuh, A. C. (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
Gertsenstein, M.4
Wu, X.F.5
Breitman, M.L.6
Schuh, A.C.7
-
8
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
Soker, S., Takashima, S., Miao, H. Q., Neufeld, G., and Klagsbrun, M. (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
9
-
-
50249094553
-
Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos
-
Jones, E. A., Yuan, L., Breant, C., Watts, R. J., and Eichmann, A. (2008) Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos. Development 135, 2479-2488
-
(2008)
Development
, vol.135
, pp. 2479-2488
-
-
Jones, E.A.1
Yuan, L.2
Breant, C.3
Watts, R.J.4
Eichmann, A.5
-
10
-
-
84877929726
-
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis
-
Fantin, A., Vieira, J. M., Plein, A., Denti, L., Fruttiger, M., Pollard, J. W., and Ruhrberg, C. (2013) NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis. Blood 121, 2352-2362
-
(2013)
Blood
, vol.121
, pp. 2352-2362
-
-
Fantin, A.1
Vieira, J.M.2
Plein, A.3
Denti, L.4
Fruttiger, M.5
Pollard, J.W.6
Ruhrberg, C.7
-
11
-
-
84934981272
-
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch
-
Aspalter, I. M., Gordon, E., Dubrac, A., Ragab, A., Narloch, J., Vizán, P., Geudens, I., Collins, R. T., Franco, C. A., Abrahams, C. L., Thurston, G., Fruttiger, M., Rosewell, I., Eichmann, A., and Gerhardt, H. (2015) Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. Nat. Commun. 6, 7264
-
(2015)
Nat. Commun
, vol.6
, pp. 7264
-
-
Aspalter, I.M.1
Gordon, E.2
Dubrac, A.3
Ragab, A.4
Narloch, J.5
Vizán, P.6
Geudens, I.7
Collins, R.T.8
Franco, C.A.9
Abrahams, C.L.10
Thurston, G.11
Fruttiger, M.12
Rosewell, I.13
Eichmann, A.14
Gerhardt, H.15
-
12
-
-
0036803751
-
Abnormal lymphatic vessel development in neuropilin 2 mutant mice
-
Yuan, L., Moyon, D., Pardanaud, L., Bréant, C., Karkkainen, M. J., Alitalo, K., and Eichmann, A. (2002) Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development 129, 4797-4806
-
(2002)
Development
, vol.129
, pp. 4797-4806
-
-
Yuan, L.1
Moyon, D.2
Pardanaud, L.3
Bréant, C.4
Karkkainen, M.J.5
Alitalo, K.6
Eichmann, A.7
-
13
-
-
33746503288
-
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
-
Kärpänen, T., Heckman, C. A., Keskitalo, S., Jeltsch, M., Ollila, H., Neufeld, G., Tamagnone, L., and Alitalo, K. (2006) Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J. 20, 1462-1472
-
(2006)
FASEB J
, vol.20
, pp. 1462-1472
-
-
Kärpänen, T.1
Heckman, C.A.2
Keskitalo, S.3
Jeltsch, M.4
Ollila, H.5
Neufeld, G.6
Tamagnone, L.7
Alitalo, K.8
-
14
-
-
41249088330
-
Blocking neuropilin-2 function inhibits tumor cell metastasis
-
Caunt, M., Mak, J., Liang, W. C., Stawicki, S., Pan, Q., Tong, R. K., Kowalski, J., Ho, C., Reslan, H. B., Ross, J., Berry, L., Kasman, I., Zlot, C., Cheng, Z., Le Couter, J., Filvaroff, E. H., Plowman, G., Peale, F., French, D., Carano, R., Koch, A. W., Wu, Y., Watts, R. J., Tessier-Lavigne, M., and Bagri, A. (2008) Blocking neuropilin-2 function inhibits tumor cell metastasis. Cancer Cell 13, 331-342
-
(2008)
Cancer Cell
, vol.13
, pp. 331-342
-
-
Caunt, M.1
Mak, J.2
Liang, W.C.3
Stawicki, S.4
Pan, Q.5
Tong, R.K.6
Kowalski, J.7
Ho, C.8
Reslan, H.B.9
Ross, J.10
Berry, L.11
Kasman, I.12
Zlot, C.13
Cheng, Z.14
Le Couter, J.15
Filvaroff, E.H.16
Plowman, G.17
Peale, F.18
French, D.19
Carano, R.20
Koch, A.W.21
Wu, Y.22
Watts, R.J.23
Tessier-Lavigne, M.24
Bagri, A.25
more..
-
15
-
-
75749124699
-
Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3
-
Xu, Y., Yuan, L., Mak, J., Pardanaud, L., Caunt, M., Kasman, I., Larrivée, B., Del Toro, R., Suchting, S., Medvinsky, A., Silva, J., Yang, J., Thomas, J. L., Koch, A. W., Alitalo, K., Eichmann, A., and Bagri, A. (2010) Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3. J. Cell Biol. 188, 115-130
-
(2010)
J. Cell Biol
, vol.188
, pp. 115-130
-
-
Xu, Y.1
Yuan, L.2
Mak, J.3
Pardanaud, L.4
Caunt, M.5
Kasman, I.6
Larrivée, B.7
Del Toro, R.8
Suchting, S.9
Medvinsky, A.10
Silva, J.11
Yang, J.12
Thomas, J.L.13
Koch, A.W.14
Alitalo, K.15
Eichmann, A.16
Bagri, A.17
-
16
-
-
0037133617
-
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis
-
Takashima, S., Kitakaze, M., Asakura, M., Asanuma, H., Sanada, S., Tashiro, F., Niwa, H., Miyazaki Ji, J., Hirota, S., Kitamura, Y., Kitsukawa, T., Fujisawa, H., Klagsbrun, M., and Hori, M. (2002) Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc. Natl. Acad. Sci. U.S.A. 99, 3657-3662
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 3657-3662
-
-
Takashima, S.1
Kitakaze, M.2
Asakura, M.3
Asanuma, H.4
Sanada, S.5
Tashiro, F.6
Niwa, H.7
Miyazaki Ji, J.8
Hirota, S.9
Kitamura, Y.10
Kitsukawa, T.11
Fujisawa, H.12
Klagsbrun, M.13
Hori, M.14
-
17
-
-
34548235938
-
Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting
-
Pan, Q., Chathery, Y., Wu, Y., Rathore, N., Tong, R. K., Peale, F., Bagri, A., Tessier-Lavigne, M., Koch, A. W., and Watts, R. J. (2007) Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. J. Biol. Chem. 282, 24049-24056
-
(2007)
J. Biol. Chem
, vol.282
, pp. 24049-24056
-
-
Pan, Q.1
Chathery, Y.2
Wu, Y.3
Rathore, N.4
Tong, R.K.5
Peale, F.6
Bagri, A.7
Tessier-Lavigne, M.8
Koch, A.W.9
Watts, R.J.10
-
18
-
-
84859488831
-
Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1
-
Parker, M. W., Xu, P., Li, X., and Vander Kooi, C. W. (2012) Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1. J. Biol. Chem. 287, 11082-11089
-
(2012)
J. Biol. Chem
, vol.287
, pp. 11082-11089
-
-
Parker, M.W.1
Xu, P.2
Li, X.3
Vander Kooi, W.C.4
-
19
-
-
84869038134
-
Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition
-
Parker, M. W., Xu, P., Guo, H. F., and Vander Kooi, C. W. (2012) Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition. PLoS ONE 7, e49177
-
(2012)
PLoS ONE
, vol.7
, pp. e49177
-
-
Parker, M.W.1
Xu, P.2
Guo, H.F.3
Vander Kooi, W.C.4
-
20
-
-
0037098860
-
VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma
-
Bates, D. O., Cui, T. G., Doughty, J. M., Winkler, M., Sugiono, M., Shields, J. D., Peat, D., Gillatt, D., and Harper, S. J. (2002) VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res. 62, 4123-4131
-
(2002)
Cancer Res
, vol.62
, pp. 4123-4131
-
-
Bates, D.O.1
Cui, T.G.2
Doughty, J.M.3
Winkler, M.4
Sugiono, M.5
Shields, J.D.6
Peat, D.7
Gillatt, D.8
Harper, S.J.9
-
21
-
-
84926466448
-
Structural basis for VEGF-C binding to neuropilin-2 and sequestration by a soluble splice form
-
Parker, M. W., Linkugel, A. D., Goel, H. L., Wu, T., Mercurio, A. M., and Vander Kooi, C. W. (2015) Structural basis for VEGF-C binding to neuropilin-2 and sequestration by a soluble splice form. Structure 23, 677-687
-
(2015)
Structure
, vol.23
, pp. 677-687
-
-
Parker, M.W.1
Linkugel, A.D.2
Goel, H.L.3
Wu, T.4
Mercurio, A.M.5
Vander Kooi, W.C.6
-
22
-
-
84926501107
-
Splicing and proteolytic processing in VEGF signaling: Now it is the coreceptor's turn
-
Yao, X., and Bouyain, S. (2015) Splicing and proteolytic processing in VEGF signaling: now it is the coreceptor's turn. Structure 23, 610-611
-
(2015)
Structure
, vol.23
, pp. 610-611
-
-
Yao, X.1
Bouyain, S.2
-
23
-
-
84906819235
-
Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice
-
Dijkstra, M. H., Pirinen, E., Huusko, J., Kivelä, R., Schenkwein, D., Alitalo, K., and Ylä-Herttuala, S. (2014) Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice. Sci. Rep. 4, 6238
-
(2014)
Sci. Rep
, vol.4
, pp. 6238
-
-
Dijkstra, M.H.1
Pirinen, E.2
Huusko, J.3
Kivelä, R.4
Schenkwein, D.5
Alitalo, K.6
Ylä-Herttuala, S.7
-
24
-
-
84867672712
-
Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes
-
Hagberg, C. E., Mehlem, A., Falkevall, A., Muhl, L., Fam, B. C., Ortsäter, H., Scotney, P., Nyqvist, D., Samén, E., Lu, L., Stone-Elander, S., Proietto, J., Andrikopoulos, S., Sjöholm, A., Nash, A., and Eriksson, U. (2012) Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes. Nature 490, 426-430
-
(2012)
Nature
, vol.490
, pp. 426-430
-
-
Hagberg, C.E.1
Mehlem, A.2
Falkevall, A.3
Muhl, L.4
Fam, B.C.5
Ortsäter, H.6
Scotney, P.7
Nyqvist, D.8
Samén, E.9
Lu, L.10
Stone-Elander, S.11
Proietto, J.12
Andrikopoulos, S.13
Sjöholm, A.14
Nash, A.15
Eriksson, U.16
-
25
-
-
33646822526
-
Tuftsin binds neuropilin-1 through a sequence similar to that encoded by exon 8 of vascular endothelial growth factor
-
von Wronski, M. A., Raju, N., Pillai, R., Bogdan, N. J., Marinelli, E. R., Nanjappan, P., Ramalingam, K., Arunachalam, T., Eaton, S., Linder, K. E., Yan, F., Pochon, S., Tweedle, M. F., and Nunn, A. D. (2006) Tuftsin binds neuropilin-1 through a sequence similar to that encoded by exon 8 of vascular endothelial growth factor. J. Biol. Chem. 281, 5702-5710
-
(2006)
J. Biol. Chem
, vol.281
, pp. 5702-5710
-
-
Von Wronski, M.A.1
Raju, N.2
Pillai, R.3
Bogdan, N.J.4
Marinelli, E.R.5
Nanjappan, P.6
Ramalingam, K.7
Arunachalam, T.8
Eaton, S.9
Linder, K.E.10
Yan, F.11
Pochon, S.12
Tweedle, M.F.13
Nunn, A.D.14
-
26
-
-
33751091501
-
Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1
-
Starzec, A., Vassy, R., Martin, A., Lecouvey, M., Di Benedetto, M., Crépin, M., and Perret, G. Y. (2006) Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1. Life Sci. 79, 2370-2381
-
(2006)
Life Sci
, vol.79
, pp. 2370-2381
-
-
Starzec, A.1
Vassy, R.2
Martin, A.3
Lecouvey, M.4
Di Benedetto, M.5
Crépin, M.6
Perret, G.Y.7
-
27
-
-
33744965754
-
Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 binding and role of NP-1 in KDR signaling
-
Jia, H., Bagherzadeh, A., Hartzoulakis, B., Jarvis, A., Löhr, M., Shaikh, S., Aqil, R., Cheng, L., Tickner, M., Esposito, D., Harris, R., Driscoll, P. C., Selwood, D. L., and Zachary, I. C. (2006) Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 binding and role of NP-1 in KDR signaling. J. Biol. Chem. 281, 13493-13502
-
(2006)
J. Biol. Chem
, vol.281
, pp. 13493-13502
-
-
Jia, H.1
Bagherzadeh, A.2
Hartzoulakis, B.3
Jarvis, A.4
Löhr, M.5
Shaikh, S.6
Aqil, R.7
Cheng, L.8
Tickner, M.9
Esposito, D.10
Harris, R.11
Driscoll, P.C.12
Selwood, D.L.13
Zachary, I.C.14
-
28
-
-
70349482671
-
C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
-
Teesalu, T., Sugahara, K. N., Kotamraju, V. R., and Ruoslahti, E. (2009) C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration. Proc. Natl. Acad. Sci. U.S.A. 106, 16157-16162
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 16157-16162
-
-
Teesalu, T.1
Sugahara, K.N.2
Kotamraju, V.R.3
Ruoslahti, E.4
-
29
-
-
77952341533
-
Furin processing of semaphorin 3F determines its antiangiogenic activity by regulating direct binding and competition for neuropilin
-
Parker, M. W., Hellman, L. M., Xu, P., Fried, M. G., and Vander Kooi, C. W. (2010) Furin processing of semaphorin 3F determines its antiangiogenic activity by regulating direct binding and competition for neuropilin. Biochemistry 49, 4068-4075
-
(2010)
Biochemistry
, vol.49
, pp. 4068-4075
-
-
Parker, M.W.1
Hellman, L.M.2
Xu, P.3
Fried, M.G.4
Vander Kooi, W.C.5
-
30
-
-
34547520925
-
Structural basis for ligand and heparin binding to neuropilin B domains
-
Vander Kooi, C. W., Jusino, M. A., Perman, B., Neau, D. B., Bellamy, H. D., and Leahy, D. J. (2007) Structural basis for ligand and heparin binding to neuropilin B domains. Proc. Natl. Acad. Sci. U.S.A. 104, 6152-6157
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 6152-6157
-
-
Vander Kooi, C.W.1
Jusino, M.A.2
Perman, B.3
Neau, D.B.4
Bellamy, H.D.5
Leahy, D.J.6
-
31
-
-
84855582590
-
Mapping of vascular ZIP codes by phage display
-
Teesalu, T., Sugahara, K. N., and Ruoslahti, E. (2012) Mapping of vascular ZIP codes by phage display. Methods Enzymol. 503, 35-56
-
(2012)
Methods Enzymol
, vol.503
, pp. 35-56
-
-
Teesalu, T.1
Sugahara, K.N.2
Ruoslahti, E.3
-
32
-
-
84930654052
-
An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability
-
Pang, H. B., Braun, G. B., Friman, T., Aza-Blanc, P., Ruidiaz, M. E., Sugahara, K. N., Teesalu, T., and Ruoslahti, E. (2014) An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability. Nat. Commun. 5, 4904
-
(2014)
Nat. Commun
, vol.5
, pp. 4904
-
-
Pang, H.B.1
Braun, G.B.2
Friman, T.3
Aza-Blanc, P.4
Ruidiaz, M.E.5
Sugahara, K.N.6
Teesalu, T.7
Ruoslahti, E.8
-
33
-
-
84991501298
-
Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding
-
Gelfand, M. V., Hagan, N., Tata, A., Oh, W. J., Lacoste, B., Kang, K. T., Kopycinska, J., Bischoff, J., Wang, J. H., and Gu, C. (2014) Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding. Elife 3, e03720
-
(2014)
Elife
, vol.3
, pp. e03720
-
-
Gelfand, M.V.1
Hagan, N.2
Tata, A.3
Oh, W.J.4
Lacoste, B.5
Kang, K.T.6
Kopycinska, J.7
Bischoff, J.8
Wang, J.H.9
Gu, C.10
-
34
-
-
0034282885
-
The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor Flt-1
-
Fuh, G., Garcia, K. C., and de Vos, A. M. (2000) The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor Flt-1. J. Biol. Chem. 275, 26690-26695
-
(2000)
J. Biol. Chem
, vol.275
, pp. 26690-26695
-
-
Fuh, G.1
Garcia, K.C.2
De Vos, A.M.3
-
35
-
-
35148839019
-
Molecular mapping and functional characterization of the VEGF164 heparin-binding domain
-
Krilleke, D., DeErkenez, A., Schubert, W., Giri, I., Robinson, G. S., Ng, Y. S., and Shima, D. T. (2007) Molecular mapping and functional characterization of the VEGF164 heparin-binding domain. J. Biol. Chem. 282, 28045-28056
-
(2007)
J. Biol. Chem
, vol.282
, pp. 28045-28056
-
-
Krilleke, D.1
DeErkenez, A.2
Schubert, W.3
Giri, I.4
Robinson, G.S.5
Ng, Y.S.6
Shima, D.T.7
-
36
-
-
84903852019
-
Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars
-
Uniewicz, K. A., Ori, A., Ahmed, Y. A., Yates, E. A., and Fernig, D. G. (2014) Characterisation of the interaction of neuropilin-1 with heparin and a heparan sulfate mimetic library of heparin-derived sugars. PeerJ 2, e461
-
(2014)
PeerJ
, vol.2
, pp. e461
-
-
Uniewicz, K.A.1
Ori, A.2
Ahmed, Y.A.3
Yates, E.A.4
Fernig, D.G.5
-
37
-
-
84941313393
-
Synergistic Binding of vascular endothelial growth factor-A and its receptors to heparin selectively modulates complex affinity
-
Teran, M., and Nugent, M. A. (2015) Synergistic Binding of vascular endothelial growth factor-A and its receptors to heparin selectively modulates complex affinity. J. Biol. Chem. 290, 16451-16462
-
(2015)
J. Biol. Chem
, vol.290
, pp. 16451-16462
-
-
Teran, M.1
Nugent, M.A.2
-
38
-
-
33746320397
-
Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling
-
Shintani, Y., Takashima, S., Asano, Y., Kato, H., Liao, Y., Yamazaki, S., Tsukamoto, O., Seguchi, O., Yamamoto, H., Fukushima, T., Sugahara, K. Kitakaze, M., and Hori, M. (2006) Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling. EMBO J. 25, 3045-3055
-
(2006)
EMBO J
, vol.25
, pp. 3045-3055
-
-
Shintani, Y.1
Takashima, S.2
Asano, Y.3
Kato, H.4
Liao, Y.5
Yamazaki, S.6
Tsukamoto, O.7
Seguchi, O.8
Yamamoto, H.9
Fukushima, T.10
Sugahara Kitakaze K, M.11
Hori, M.12
-
39
-
-
84867848485
-
Plexin structures are coming: Opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions
-
Hota, P. K., and Buck, M. (2012) Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions. Cell. Mol. Life Sci. 69, 3765-3805
-
(2012)
Cell. Mol. Life Sci
, vol.69
, pp. 3765-3805
-
-
Hota, P.K.1
Buck, M.2
-
40
-
-
0037124068
-
Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165
-
Gu, C., Limberg, B. J., Whitaker, G. B., Perman, B., Leahy, D. J., Rosenbaum, J. S., Ginty, D. D., and Kolodkin, A. L. (2002) Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. J. Biol. Chem. 277, 18069-18076
-
(2002)
J. Biol. Chem
, vol.277
, pp. 18069-18076
-
-
Gu, C.1
Limberg, B.J.2
Whitaker, G.B.3
Perman, B.4
Leahy, D.J.5
Rosenbaum, J.S.6
Ginty, D.D.7
Kolodkin, A.L.8
-
41
-
-
77951619146
-
A forward genetic screen in mice identifies Sema3AK108N, which binds to neuropilin-1 but cannot signal
-
Merte, J., Wang, Q., Vander Kooi, C. W., Sarsfield, S., Leahy, D. J., Kolodkin, A. L., and Ginty, D. D. (2010) A forward genetic screen in mice identifies Sema3AK108N, which binds to neuropilin-1 but cannot signal. J. Neurosci. 30, 5767-5775
-
(2010)
J. Neurosci
, vol.30
, pp. 5767-5775
-
-
Merte, J.1
Wang, Q.2
Vander Kooi, C.W.3
Sarsfield, S.4
Leahy, D.J.5
Kolodkin, A.L.6
Ginty, D.D.7
-
42
-
-
84870784265
-
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex
-
Janssen, B. J., Malinauskas, T., Weir, G. A., Cader, M. Z., Siebold, C., and Jones, E. Y. (2012) Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat. Struct. Mol. Biol. 19, 1293-1299
-
(2012)
Nat. Struct. Mol. Biol
, vol.19
, pp. 1293-1299
-
-
Janssen, B.J.1
Malinauskas, T.2
Weir, G.A.3
Cader, M.Z.4
Siebold, C.5
Jones, E.Y.6
-
43
-
-
0030722135
-
The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing
-
Adams, R. H., Lohrum, M., Klostermann, A., Betz, H., and Püschel, A. W. (1997) The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing. EMBO J. 16, 6077-6086
-
(1997)
EMBO J
, vol.16
, pp. 6077-6086
-
-
Adams, R.H.1
Lohrum, M.2
Klostermann, A.3
Betz, H.4
Püschel, A.W.5
-
44
-
-
84866166943
-
SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome
-
Hanchate, N. K., Giacobini, P., Lhuillier, P., Parkash, J., Espy, C., Fouveaut, C., Leroy, C., Baron, S., Campagne, C., Vanacker, C., Collier, F., Cruaud, C., Meyer, V., García-Piñero, A., Dewailly, D., Cortet-Rudelli, C., Gersak, K., Metz, C., Chabrier, G., Pugeat, M., Young, J., Hardelin, J. P., Prevot, V., and Dodé, C. (2012) SEMA3A, a gene involved in axonal pathfinding, is mutated in patients with Kallmann syndrome. PLoS Genet. 8, e1002896
-
(2012)
PLoS Genet
, vol.8
, pp. e1002896
-
-
Hanchate, N.K.1
Giacobini, P.2
Lhuillier, P.3
Parkash, J.4
Espy, C.5
Fouveaut, C.6
Leroy, C.7
Baron, S.8
Campagne, C.9
Vanacker, C.10
Collier, F.11
Cruaud, C.12
Meyer, V.13
García-Piñero, A.14
Dewailly, D.15
Cortet-Rudelli, C.16
Gersak, K.17
Metz, C.18
Chabrier, G.19
Pugeat, M.20
Young, J.21
Hardelin, J.P.22
Prevot, V.23
Dodé, C.24
more..
-
45
-
-
84884206864
-
Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis
-
Delgoffe, G. M., Woo, S. R., Turnis, M. E., Gravano, D. M., Guy, C., Overacre, A. E., Bettini, M. L., Vogel, P., Finkelstein, D., Bonnevier, J., Workman, C. J., and Vignali, D. A. (2013) Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature 501, 252-256
-
(2013)
Nature
, vol.501
, pp. 252-256
-
-
Delgoffe, G.M.1
Woo, S.R.2
Turnis, M.E.3
Gravano, D.M.4
Guy, C.5
Overacre, A.E.6
Bettini, M.L.7
Vogel, P.8
Finkelstein, D.9
Bonnevier, J.10
Workman, C.J.11
Vignali, D.A.12
-
46
-
-
84942816655
-
Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesis
-
Yang, W. J., Hu, J., Uemura, A., Tetzlaff, F., Augustin, H. G., and Fischer, A. (2015) Semaphorin-3C signals through Neuropilin-1 and PlexinD1 receptors to inhibit pathological angiogenesis. EMBO Mol. Med. 7, 1267-1284
-
(2015)
EMBO Mol. Med
, vol.7
, pp. 1267-1284
-
-
Yang, W.J.1
Hu, J.2
Uemura, A.3
Tetzlaff, F.4
Augustin, H.G.5
Fischer, A.6
-
47
-
-
84937019661
-
Regulation of mTOR signaling by Semaphorin 3F-Neuropilin 2 interactions in vitro and in vivo
-
Nakayama, H., Bruneau, S., Kochupurakkal, N., Coma, S., Briscoe, D. M., and Klagsbrun, M. (2015) Regulation of mTOR signaling by Semaphorin 3F-Neuropilin 2 interactions in vitro and in vivo. Sci. Rep. 5, 11789
-
(2015)
Sci. Rep
, vol.5
, pp. 11789
-
-
Nakayama, H.1
Bruneau, S.2
Kochupurakkal, N.3
Coma, S.4
Briscoe, D.M.5
Klagsbrun, M.6
-
48
-
-
84934881264
-
Full-Length Semaphorin-3C is an inhibitor of tumor lymphangiogenesis and metastasis
-
Mumblat, Y., Kessler, O., Ilan, N., and Neufeld, G. (2015) Full-Length Semaphorin-3C is an inhibitor of tumor lymphangiogenesis and metastasis. Cancer Res. 75, 2177-2186
-
(2015)
Cancer Res
, vol.75
, pp. 2177-2186
-
-
Mumblat, Y.1
Kessler, O.2
Ilan, N.3
Neufeld, G.4
-
49
-
-
0038686623
-
Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
-
Gu, C., Rodriguez, E. R., Reimert, D. V., Shu, T., Fritzsch, B., Richards, L. J., Kolodkin, A. L., and Ginty, D. D. (2003) Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev. Cell 5, 45-57
-
(2003)
Dev. Cell
, vol.5
, pp. 45-57
-
-
Gu, C.1
Rodriguez, E.R.2
Reimert, D.V.3
Shu, T.4
Fritzsch, B.5
Richards, L.J.6
Kolodkin, A.L.7
Ginty, D.D.8
-
50
-
-
0041530325
-
Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
-
Serini, G., Valdembri, D., Zanivan, S., Morterra, G., Burkhardt, C., Caccavari, F., Zammataro, L., Primo, L., Tamagnone, L., Logan, M., Tessier-Lavigne, M., Taniguchi, M., Püschel, A. W., and Bussolino, F. (2003) Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 424, 391-397
-
(2003)
Nature
, vol.424
, pp. 391-397
-
-
Serini, G.1
Valdembri, D.2
Zanivan, S.3
Morterra, G.4
Burkhardt, C.5
Caccavari, F.6
Zammataro, L.7
Primo, L.8
Tamagnone, L.9
Logan, M.10
Tessier-Lavigne, M.11
Taniguchi, M.12
Püschel, A.W.13
Bussolino, F.14
-
51
-
-
79961213450
-
Semaphorin signals on the road of endothelial tip cells
-
Tamagnone, L., and Mazzone, M. (2011) Semaphorin signals on the road of endothelial tip cells. Dev. Cell 21, 189-190
-
(2011)
Dev. Cell
, vol.21
, pp. 189-190
-
-
Tamagnone, L.1
Mazzone, M.2
-
52
-
-
84887061696
-
Mechanistic basis for the potent anti-angiogenic activity of Semaphorin 3F
-
Guo, H. F., Li, X., Parker, M. W., Waltenberger, J., Becker, P. M., and Vander Kooi, C. W. (2013) Mechanistic basis for the potent anti-angiogenic activity of Semaphorin 3F. Biochemistry 52, 7551-7558
-
(2013)
Biochemistry
, vol.52
, pp. 7551-7558
-
-
Guo, H.F.1
Li, X.2
Parker, M.W.3
Waltenberger, J.4
Becker, P.M.5
Vander Kooi, W.C.6
-
53
-
-
84886725991
-
Effect of C-terminal sequence on competitive Semaphorin binding to Neuropilin-1
-
Parker, M. W., Linkugel, A. D., and Vander Kooi, C. W. (2013) Effect of C-terminal sequence on competitive Semaphorin binding to Neuropilin-1. J. Mol. Biol. J. Mol. Biol. 425, 4405-4414
-
(2013)
J. Mol. Biol. J. Mol. Biol
, vol.425
, pp. 4405-4414
-
-
Parker, M.W.1
Linkugel, A.D.2
Vander Kooi, W.C.3
-
54
-
-
0141816865
-
Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells
-
Bachelder, R. E., Lipscomb, E. A., Lin, X., Wendt, M. A., Chadborn, N. H., Eickholt, B. J., and Mercurio, A. M. (2003) Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. Cancer Res. 63, 5230-5233
-
(2003)
Cancer Res
, vol.63
, pp. 5230-5233
-
-
Bachelder, R.E.1
Lipscomb, E.A.2
Lin, X.3
Wendt, M.A.4
Chadborn, N.H.5
Eickholt, B.J.6
Mercurio, A.M.7
-
55
-
-
84877300380
-
Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer
-
Bender, R. J., and Mac Gabhann, F. (2013) Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer. PLoS ONE 8, e61788
-
(2013)
PLoS ONE
, vol.8
, pp. e61788
-
-
Bender, R.J.1
Mac Gabhann, F.2
-
56
-
-
33745772365
-
Neuropilin-1 is involved in human T-cell lymphotropic virus type 1 entry
-
Ghez, D., Lepelletier, Y., Lambert, S., Fourneau, J. M., Blot, V., Janvier, S., Arnulf, B., van Endert, P. M., Heveker, N., Pique, C., and Hermine, O. (2006) Neuropilin-1 is involved in human T-cell lymphotropic virus type 1 entry. J. Virol. 80, 6844-6854
-
(2006)
J. Virol
, vol.80
, pp. 6844-6854
-
-
Ghez, D.1
Lepelletier, Y.2
Lambert, S.3
Fourneau, J.M.4
Blot, V.5
Janvier, S.6
Arnulf, B.7
Van Endert, P.M.8
Heveker, N.9
Pique, C.10
Hermine, O.11
-
57
-
-
65949101737
-
HTLV-1 uses HSPG and neuropilin-1 for entry by molecular mimicry of VEGF165
-
Lambert, S., Bouttier, M., Vassy, R., Seigneuret, M., Petrow-Sadowski, C., Janvier, S., Heveker, N., Ruscetti, F. W., Perret, G., Jones, K. S., and Pique, C. (2009) HTLV-1 uses HSPG and neuropilin-1 for entry by molecular mimicry of VEGF165. Blood 113, 5176-5185
-
(2009)
Blood
, vol.113
, pp. 5176-5185
-
-
Lambert, S.1
Bouttier, M.2
Vassy, R.3
Seigneuret, M.4
Petrow-Sadowski, C.5
Janvier, S.6
Heveker, N.7
Ruscetti, F.W.8
Perret, G.9
Jones, K.S.10
Pique, C.11
-
58
-
-
84923108419
-
Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells
-
Wang, H. B., Zhang, H., Zhang, J. P., Li, Y., Zhao, B., Feng, G. K., Du, Y., Xiong, D., Zhong, Q., Liu, W. L., Du, H., Li, M. Z., Huang, W. L., Tsao, S. W., Hutt-Fletcher, L., Zeng, Y. X., Kieff, E., and Zeng, M. S. (2015) Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells. Nat. Commun. 6, 6240
-
(2015)
Nat. Commun
, vol.6
, pp. 6240
-
-
Wang, H.B.1
Zhang, H.2
Zhang, J.P.3
Li, Y.4
Zhao, B.5
Feng, G.K.6
Du, Y.7
Xiong, D.8
Zhong, Q.9
Liu, W.L.10
Du, H.11
Li, M.Z.12
Huang, W.L.13
Tsao, S.W.14
Hutt-Fletcher, L.15
Zeng, Y.X.16
Kieff, E.17
Zeng, M.S.18
-
59
-
-
0035869241
-
Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis
-
Yamada, Y., Takakura, N., Yasue, H., Ogawa, H., Fujisawa, H., and Suda, T. (2001) Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis. Blood 97, 1671-1678
-
(2001)
Blood
, vol.97
, pp. 1671-1678
-
-
Yamada, Y.1
Takakura, N.2
Yasue, H.3
Ogawa, H.4
Fujisawa, H.5
Suda, T.6
-
60
-
-
78650954703
-
Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis
-
Uniewicz, K. A., Cross, M. J., and Fernig, D. G. (2011) Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis. J. Biol. Chem. 286, 12-23
-
(2011)
J. Biol. Chem
, vol.286
, pp. 12-23
-
-
Uniewicz, K.A.1
Cross, M.J.2
Fernig, D.G.3
-
61
-
-
0034646262
-
Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity
-
Gagnon, M. L., Bielenberg, D. R., Gechtman, Z., Miao, H. Q., Takashima, S., Soker, S., and Klagsbrun, M. (2000) Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: in vivo expression and antitumor activity. Proc. Natl. Acad. Sci. U.S.A. 97, 2573-2578
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 2573-2578
-
-
Gagnon, M.L.1
Bielenberg, D.R.2
Gechtman, Z.3
Miao, H.Q.4
Takashima, S.5
Soker, S.6
Klagsbrun, M.7
-
62
-
-
0034545620
-
Genomic organization of human neuropilin-1 and neuropilin-2 genes: Identification and distribution of splice variants and soluble isoforms
-
Rossignol, M., Gagnon, M. L., and Klagsbrun, M. (2000) Genomic organization of human neuropilin-1 and neuropilin-2 genes: identification and distribution of splice variants and soluble isoforms. Genomics 70, 211-222
-
(2000)
Genomics
, vol.70
, pp. 211-222
-
-
Rossignol, M.1
Gagnon, M.L.2
Klagsbrun, M.3
-
63
-
-
0037114642
-
In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo
-
Schuch, G., Machluf, M., Bartsch, G., Jr., Nomi, M., Richard, H., Atala, A., and Soker, S. (2002) In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo. Blood 100, 4622-4628
-
(2002)
Blood
, vol.100
, pp. 4622-4628
-
-
Schuch, G.1
Machluf, M.2
Bartsch, G.3
Nomi, M.4
Richard, H.5
Atala, A.6
Soker, S.7
-
64
-
-
55449114832
-
VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling
-
Swendeman, S., Mendelson, K., Weskamp, G., Horiuchi, K., Deutsch, U., Scherle, P., Hooper, A., Rafii, S., and Blobel, C. P. (2008) VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circ. Res. 103, 916-918
-
(2008)
Circ. Res
, vol.103
, pp. 916-918
-
-
Swendeman, S.1
Mendelson, K.2
Weskamp, G.3
Horiuchi, K.4
Deutsch, U.5
Scherle, P.6
Hooper, A.7
Rafii, S.8
Blobel, C.P.9
-
65
-
-
84926500685
-
Circulating soluble neuropilin-1 in patients with early cervical cancer and cervical intraepithelial neoplasia can be used as a valuable diagnostic biomarker
-
Yang, S., Cheng, H., Huang, Z., Wang, X., Wan, Y., Cai, J., and Wang, Z. (2015) Circulating soluble neuropilin-1 in patients with early cervical cancer and cervical intraepithelial neoplasia can be used as a valuable diagnostic biomarker. Dis. Markers 2015, 506428
-
(2015)
Dis. Markers 2015
, pp. 506428
-
-
Yang, S.1
Cheng, H.2
Huang, Z.3
Wang, X.4
Wan, Y.5
Cai, J.6
Wang, Z.7
-
66
-
-
80052515065
-
The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins
-
Fantin, A., Schwarz, Q., Davidson, K., Normando, E. M., Denti, L., and Ruhrberg, C. (2011) The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins. Development 138, 4185-4191
-
(2011)
Development
, vol.138
, pp. 4185-4191
-
-
Fantin, A.1
Schwarz, Q.2
Davidson, K.3
Normando, E.M.4
Denti, L.5
Ruhrberg, C.6
-
67
-
-
84876976777
-
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis
-
Lanahan, A., Zhang, X., Fantin, A., Zhuang, Z., Rivera-Molina, F., Speichinger, K., Prahst, C., Zhang, J., Wang, Y., Davis, G., Toomre, D., Ruhrberg, C., and Simons, M. (2013) The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev. Cell 25, 156-168
-
(2013)
Dev. Cell
, vol.25
, pp. 156-168
-
-
Lanahan, A.1
Zhang, X.2
Fantin, A.3
Zhuang, Z.4
Rivera-Molina, F.5
Speichinger, K.6
Prahst, C.7
Zhang, J.8
Wang, Y.9
Davis, G.10
Toomre, D.11
Ruhrberg, C.12
Simons, M.13
-
68
-
-
0033179591
-
Cloning and characterization of neuropilin-1-interacting protein: A PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1
-
Cai, H., and Reed, R. R. (1999) Cloning and characterization of neuropilin-1-interacting protein: a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1. J. Neurosci. 19, 6519-6527
-
(1999)
J. Neurosci
, vol.19
, pp. 6519-6527
-
-
Cai, H.1
Reed, R.R.2
-
69
-
-
33845678052
-
C terminus of RGSGAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis
-
Wang, L., Mukhopadhyay, D., and Xu, X. (2006) C terminus of RGSGAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB J. 20, 1513-1515
-
(2006)
FASEB J
, vol.20
, pp. 1513-1515
-
-
Wang, L.1
Mukhopadhyay, D.2
Xu, X.3
-
70
-
-
33744483170
-
Selective regulation of arterial branching morphogenesis by synectin
-
Chittenden, T. W., Claes, F., Lanahan, A. A., Autiero, M., Palac, R. T., Tkachenko, E. V., Elfenbein, A., Ruiz de Almodovar, C., Dedkov, E., Tomanek, R., Li, W., Westmore, M., Singh, J. P., Horowitz, A., Mulligan-Kehoe, M. J., Moodie, K. L., Zhuang, Z. W., Carmeliet, P., and Simons, M. (2006) Selective regulation of arterial branching morphogenesis by synectin. Dev. Cell 10, 783-795
-
(2006)
Dev. Cell
, vol.10
, pp. 783-795
-
-
Chittenden, T.W.1
Claes, F.2
Lanahan, A.A.3
Autiero, M.4
Palac, R.T.5
Tkachenko, E.V.6
Elfenbein, A.7
Ruiz De Almodovar, C.8
Dedkov, E.9
Tomanek, R.10
Li, W.11
Westmore, M.12
Singh, J.P.13
Horowitz, A.14
Mulligan-Kehoe, M.J.15
Moodie, K.L.16
Zhuang, Z.W.17
Carmeliet, P.18
Simons, M.19
-
71
-
-
54449093538
-
Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1
-
Prahst, C., Héroult, M., Lanahan, A. A., Uziel, N., Kessler, O., Shraga-Heled, N., Simons, M., Neufeld, G., and Augustin, H. G. (2008) Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1. J. Biol. Chem. 283, 25110-25114
-
(2008)
J. Biol. Chem
, vol.283
, pp. 25110-25114
-
-
Prahst, C.1
Héroult, M.2
Lanahan, A.A.3
Uziel, N.4
Kessler, O.5
Shraga-Heled, N.6
Simons, M.7
Neufeld, G.8
Augustin, H.G.9
-
72
-
-
58849090461
-
Neuropilin-1/GIPC1 signaling regulatesα5β1 integrin traffic and function in endothelial cells
-
Valdembri, D., Caswell, P. T., Anderson, K. I., Schwarz, J. P., König, I., Astanina, E., Caccavari, F., Norman, J. C., Humphries, M. J., Bussolino, F., and Serini, G. (2009) Neuropilin-1/GIPC1 signaling regulatesα5β1 integrin traffic and function in endothelial cells. PLoS Biol. 7, e25
-
(2009)
PLoS Biol
, vol.7
, pp. e25
-
-
Valdembri, D.1
Caswell, P.T.2
Anderson, K.I.3
Schwarz, J.P.4
König, I.5
Astanina, E.6
Caccavari, F.7
Norman, J.C.8
Humphries, M.J.9
Bussolino, F.10
Serini, G.11
-
73
-
-
84855261162
-
The reception and the party after: How vascular endothelial growth factor receptor 2 explores cytoplasmic space
-
Berger, P., and Ballmer-Hofer, K. (2011) The reception and the party after: how vascular endothelial growth factor receptor 2 explores cytoplasmic space. Swiss Med. Wkly. 141, w13318
-
(2011)
Swiss Med. Wkly
, vol.141
, pp. w13318
-
-
Berger, P.1
Ballmer-Hofer, K.2
-
74
-
-
84886285242
-
The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnover
-
Seerapu, H. R., Borthakur, S., Kong, N., Agrawal, S., Drazba, J., Vasanji, A., Fantin, A., Ruhrberg, C., Buck, M., and Horowitz, A. (2013) The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnover. FEBS Lett. 587, 3392-3399
-
(2013)
FEBS Lett
, vol.587
, pp. 3392-3399
-
-
Seerapu, H.R.1
Borthakur, S.2
Kong, N.3
Agrawal, S.4
Drazba, J.5
Vasanji, A.6
Fantin, A.7
Ruhrberg, C.8
Buck, M.9
Horowitz, A.10
-
75
-
-
24344442787
-
GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: Evidence supporting an adapter function for GLUT1CBP
-
Reed, B. C., Cefalu, C., Bellaire, B. H., Cardelli, J. A., Louis, T., Salamon, J., Bloecher, M. A., and Bunn, R. C. (2005) GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP. Mol. Biol. Cell 16, 4183-4201
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4183-4201
-
-
Reed, B.C.1
Cefalu, C.2
Bellaire, B.H.3
Cardelli, J.A.4
Louis, T.5
Salamon, J.6
Bloecher, M.A.7
Bunn, R.C.8
-
76
-
-
33748077106
-
Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles
-
Naccache, S. N., Hasson, T., and Horowitz, A. (2006) Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles. Proc. Natl. Acad. Sci. U.S.A. 103, 12735-12740
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 12735-12740
-
-
Naccache, S.N.1
Hasson, T.2
Horowitz, A.3
-
77
-
-
84876810591
-
Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer
-
Staton, C. A., Koay, I., Wu, J. M., Hoh, L., Reed, M. W., and Brown, N. J. (2013) Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer. Histopathology 62, 908-915
-
(2013)
Histopathology
, vol.62
, pp. 908-915
-
-
Staton, C.A.1
Koay, I.2
Wu, J.M.3
Hoh, L.4
Reed, M.W.5
Brown, N.J.6
-
78
-
-
0037369210
-
Neuropilin-1 on hematopoietic cells as a source of vascular development
-
Yamada, Y., Oike, Y., Ogawa, H., Ito, Y., Fujisawa, H., Suda, T., and Takakura, N. (2003) Neuropilin-1 on hematopoietic cells as a source of vascular development. Blood 101, 1801-1809
-
(2003)
Blood
, vol.101
, pp. 1801-1809
-
-
Yamada, Y.1
Oike, Y.2
Ogawa, H.3
Ito, Y.4
Fujisawa, H.5
Suda, T.6
Takakura, N.7
-
79
-
-
84897421093
-
NRP1 presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation
-
Koch, S., van Meeteren, L. A., Morin, E., Testini, C., Weström, S., Björkelund, H., Le Jan, S., Adler, J., Berger, P., and Claesson-Welsh, L. (2014) NRP1 presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation. Dev. Cell 28, 633-646
-
(2014)
Dev. Cell
, vol.28
, pp. 633-646
-
-
Koch, S.1
Van Meeteren, L.A.2
Morin, E.3
Testini, C.4
Weström, S.5
Björkelund, H.6
Le Jan, S.7
Adler, J.8
Berger, P.9
Claesson-Welsh, L.10
-
80
-
-
0033674846
-
Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression
-
Miao, H. Q., Lee, P., Lin, H., Soker, S., and Klagsbrun, M. (2000) Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression. FASEB J. 14, 2532-2539
-
(2000)
FASEB J
, vol.14
, pp. 2532-2539
-
-
Miao, H.Q.1
Lee, P.2
Lin, H.3
Soker, S.4
Klagsbrun, M.5
-
81
-
-
84880867496
-
Neuropilin-2 promotes extravasation and metastasis by interacting with endothelialα5 integrin
-
Cao, Y., Hoeppner, L. H., Bach, S., Guangqi, E., Guo, Y., Wang, E., Wu, J., Cowley, M. J., Chang, D. K., Waddell, N., Grimmond, S. M., Biankin, A. V., Daly, R. J., Zhang, X., and Mukhopadhyay, D. (2013) Neuropilin-2 promotes extravasation and metastasis by interacting with endothelialα5 integrin. Cancer Res. 73, 4579-4590
-
(2013)
Cancer Res
, vol.73
, pp. 4579-4590
-
-
Cao, Y.1
Hoeppner, L.H.2
Bach, S.3
Guangqi, E.4
Guo, Y.5
Wang, E.6
Wu, J.7
Cowley, M.J.8
Chang, D.K.9
Waddell, N.10
Grimmond, S.M.11
Biankin, A.V.12
Daly, R.J.13
Zhang, X.14
Mukhopadhyay, D.15
-
82
-
-
1542571789
-
Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration
-
Wang, L., Zeng, H., Wang, P., Soker, S., and Mukhopadhyay, D. (2003) Neuropilin-1-mediated vascular permeability factor/vascular endothelial growth factor-dependent endothelial cell migration. J. Biol. Chem. 278, 48848-48860
-
(2003)
J. Biol. Chem
, vol.278
, pp. 48848-48860
-
-
Wang, L.1
Zeng, H.2
Wang, P.3
Soker, S.4
Mukhopadhyay, D.5
-
83
-
-
79952255709
-
Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells
-
Evans, I. M., Yamaji, M., Britton, G., Pellet-Many, C., Lockie, C., Zachary, I. C., and Frankel, P. (2011) Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Mol. Cell. Biol. 31, 1174-1185
-
(2011)
Mol. Cell. Biol
, vol.31
, pp. 1174-1185
-
-
Evans, I.M.1
Yamaji, M.2
Britton, G.3
Pellet-Many, C.4
Lockie, C.5
Zachary, I.C.6
Frankel, P.7
-
84
-
-
84921595875
-
Neuropilin-2 mediates lymphangiogenesis of colorectal carcinoma via a VEGFC/VEGFR3 independent signaling
-
Ou, J. J., Wei, X., Peng, Y., Zha, L., Zhou, R. B., Shi, H., Zhou, Q., and Liang, H. J. (2015) Neuropilin-2 mediates lymphangiogenesis of colorectal carcinoma via a VEGFC/VEGFR3 independent signaling. Cancer Lett. 358, 200-209
-
(2015)
Cancer Lett
, vol.358
, pp. 200-209
-
-
Ou, J.J.1
Wei, X.2
Peng, Y.3
Zha, L.4
Zhou, R.B.5
Shi, H.6
Zhou, Q.7
Liang, H.J.8
-
85
-
-
20244362645
-
Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2
-
West, D. C., Rees, C. G., Duchesne, L., Patey, S. J., Terry, C. J., Turnbull, J. E., Delehedde, M., Heegaard, C. W., Allain, F., Vanpouille, C., Ron, D., and Fernig, D. G. (2005) Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2. J. Biol. Chem. 280, 13457-13464
-
(2005)
J. Biol. Chem
, vol.280
, pp. 13457-13464
-
-
West, D.C.1
Rees, C.G.2
Duchesne, L.3
Patey, S.J.4
Terry, C.J.5
Turnbull, J.E.6
Delehedde, M.7
Heegaard, C.W.8
Allain, F.9
Vanpouille, C.10
Ron, D.11
Fernig, D.G.12
-
86
-
-
33750457687
-
Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1
-
Banerjee, S., Sengupta, K., Dhar, K., Mehta, S., D'Amore, P. A., Dhar, G., and Banerjee, S. K. (2006) Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1. Mol. Carcinog. 45, 871-880
-
(2006)
Mol. Carcinog
, vol.45
, pp. 871-880
-
-
Banerjee, S.1
Sengupta, K.2
Dhar, K.3
Mehta, S.4
D'Amore, P.A.5
Dhar, G.6
Banerjee, S.K.7
-
87
-
-
46949088806
-
Neuropilin-1 is a receptor for transforming growth factorβ-1, activates its latent form, and promotes regulatory T cell activity
-
Glinka, Y., and Prud'homme, G. J. (2008) Neuropilin-1 is a receptor for transforming growth factorβ-1, activates its latent form, and promotes regulatory T cell activity. J. Leukoc. Biol. 84, 302-310
-
(2008)
J. Leukoc. Biol
, vol.84
, pp. 302-310
-
-
Glinka, Y.1
Prud'Homme, G.J.2
-
88
-
-
84941564643
-
Suppressing ∼3-integrin triggers a neuropilin-1 dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis
-
Ellison, T. S., Atkinson, S. J., Steri, V., Kirkup, B. M., Preedy, M. E., Johnson, R. T., Ruhrberg, C., Edwards, D. R., Schneider, J. G., Weilbaecher, K., and Robinson, S. D. (2015) Suppressing ∼3-integrin triggers a neuropilin-1 dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis. Dis. Model. Mech. 8, 1105-1119
-
(2015)
Dis. Model. Mech
, vol.8
, pp. 1105-1119
-
-
Ellison, T.S.1
Atkinson, S.J.2
Steri, V.3
Kirkup, B.M.4
Preedy, M.E.5
Johnson, R.T.6
Ruhrberg, C.7
Edwards, D.R.8
Schneider, J.G.9
Weilbaecher, K.10
Robinson, S.D.11
-
89
-
-
35948965519
-
Neuropilin-1 interacts with integrinβ1 and modulates pancreatic cancer cell growth, survival and invasion
-
Fukasawa, M., Matsushita, A., and Korc, M. (2007) Neuropilin-1 interacts with integrinβ1 and modulates pancreatic cancer cell growth, survival and invasion. Cancer Biol. Ther. 6, 1173-1180
-
(2007)
Cancer Biol. Ther
, vol.6
, pp. 1173-1180
-
-
Fukasawa, M.1
Matsushita, A.2
Korc, M.3
-
90
-
-
84865140752
-
Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment
-
Yaqoob, U., Cao, S., Shergill, U., Jagavelu, K., Geng, Z., Yin, M., de Assuncao, T. M., Cao, Y., Szabolcs, A., Thorgeirsson, S., Schwartz, M., Yang, J. D., Ehman, R., Roberts, L., Mukhopadhyay, D., and Shah, V. H. (2012) Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment. Cancer Res. 72, 4047-4059
-
(2012)
Cancer Res
, vol.72
, pp. 4047-4059
-
-
Yaqoob, U.1
Cao, S.2
Shergill, U.3
Jagavelu, K.4
Geng, Z.5
Yin, M.6
De Assuncao, T.M.7
Cao, Y.8
Szabolcs, A.9
Thorgeirsson, S.10
Schwartz, M.11
Yang, J.D.12
Ehman, R.13
Roberts, L.14
Mukhopadhyay, D.15
Shah, V.H.16
-
91
-
-
84858118438
-
Neuropilin-2 regulatesα6β1 integrin in the formation of focal adhesions and signaling
-
Goel, H. L., Pursell, B., Standley, C., Fogarty, K., and Mercurio, A. M. (2012) Neuropilin-2 regulatesα6β1 integrin in the formation of focal adhesions and signaling. J. Cell Sci. 125, 497-506
-
(2012)
J. Cell Sci
, vol.125
, pp. 497-506
-
-
Goel, H.L.1
Pursell, B.2
Standley, C.3
Fogarty, K.4
Mercurio, A.M.5
-
92
-
-
84875804419
-
GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
-
Goel, H. L., Pursell, B., Chang, C., Shaw, L. M., Mao, J., Simin, K., Kumar, P., Vander Kooi, C. W., Shultz, L. D., Greiner, D. L., Norum, J. H., Toftgard, R., Kuperwasser, C., and Mercurio, A. M. (2013) GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol. Med. 5, 488-508
-
(2013)
EMBO Mol. Med
, vol.5
, pp. 488-508
-
-
Goel, H.L.1
Pursell, B.2
Chang, C.3
Shaw, L.M.4
Mao, J.5
Simin, K.6
Kumar, P.7
Vander Kooi, C.W.8
Shultz, L.D.9
Greiner, D.L.10
Norum, J.H.11
Toftgard, R.12
Kuperwasser, C.13
Mercurio, A.M.14
-
93
-
-
84945157013
-
GPNMB cooperates with neuropilin-1 to promote mammary tumor growth and engages integrinα for efficient breast cancer metastasis
-
Maric, G., Annis, M. G., Dong, Z., Rose, A. A., Ng, S., Perkins, D., Mac-Donald, P. A., Ouellet, V., Russo, C., and Siegel, P. M. (2015) GPNMB cooperates with neuropilin-1 to promote mammary tumor growth and engages integrinα for efficient breast cancer metastasis. Oncogene 34, 5494-5504
-
(2015)
Oncogene
, vol.34
, pp. 5494-5504
-
-
Maric, G.1
Annis, M.G.2
Dong, Z.3
Rose, A.A.4
Ng, S.5
Perkins, D.6
Mac-Donald, P.A.7
Ouellet, V.8
Russo, C.9
Siegel, P.M.10
-
94
-
-
84899962484
-
Regulated splicing of theα6 integrin cytoplasmic domain determines the fate of breast cancer stem cells
-
Goel, H. L., Gritsko, T., Pursell, B., Chang, C., Shultz, L. D., Greiner, D. L., Norum, J. H., Toftgard, R., Shaw, L. M., and Mercurio, A. M. (2014) Regulated splicing of theα6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. Cell Rep. 7, 747-761
-
(2014)
Cell Rep
, vol.7
, pp. 747-761
-
-
Goel, H.L.1
Gritsko, T.2
Pursell, B.3
Chang, C.4
Shultz, L.D.5
Greiner, D.L.6
Norum, J.H.7
Toftgard, R.8
Shaw, L.M.9
Mercurio, A.M.10
-
95
-
-
71749099202
-
V ∼3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis
-
Robinson, S. D., Reynolds, L. E., Kostourou, V., Reynolds, A. R., da Silva, R. G., Tavora, B., Baker, M., Marshall, J. F., and Hodivala-Dilke, K. M. (2009)v ∼3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis. J. Biol. Chem. 284, 33966-33981
-
(2009)
J. Biol. Chem
, vol.284
, pp. 33966-33981
-
-
Robinson, S.D.1
Reynolds, L.E.2
Kostourou, V.3
Reynolds, A.R.4
Da Silva, R.G.5
Tavora, B.6
Baker, M.7
Marshall, J.F.8
Hodivala-Dilke, K.M.9
-
96
-
-
84901760004
-
Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells
-
Raimondi, C., Fantin, A., Lampropoulou, A., Denti, L., Chikh, A., and Ruhrberg, C. (2014) Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. J. Exp. Med. 211, 1167-1183
-
(2014)
J. Exp. Med
, vol.211
, pp. 1167-1183
-
-
Raimondi, C.1
Fantin, A.2
Lampropoulou, A.3
Denti, L.4
Chikh, A.5
Ruhrberg, C.6
-
97
-
-
33845927886
-
Molecular pathways regulating pro-migratory effects of Hedgehog signaling
-
Hochman, E., Castiel, A., Jacob-Hirsch, J., Amariglio, N., and Izraeli, S. (2006) Molecular pathways regulating pro-migratory effects of Hedgehog signaling. J. Biol. Chem. 281, 33860-33870
-
(2006)
J. Biol. Chem
, vol.281
, pp. 33860-33870
-
-
Hochman, E.1
Castiel, A.2
Jacob-Hirsch, J.3
Amariglio, N.4
Izraeli, S.5
-
98
-
-
81255195354
-
Neuropilins are positive regulators of Hedgehog signal transduction
-
Hillman, R. T., Feng, B. Y., Ni, J., Woo, W. M., Milenkovic, L., Hayden Gephart, M. G., Teruel, M. N., Oro, A. E., Chen, J. K., and Scott, M. P. (2011) Neuropilins are positive regulators of Hedgehog signal transduction. Genes Dev. 25, 2333-2346
-
(2011)
Genes Dev
, vol.25
, pp. 2333-2346
-
-
Hillman, R.T.1
Feng, B.Y.2
Ni, J.3
Woo, W.M.4
Milenkovic, L.5
Hayden Gephart, M.G.6
Teruel, M.N.7
Oro, A.E.8
Chen, J.K.9
Scott, M.P.10
-
99
-
-
55349113212
-
Neuropilin-1 upholds dedifferentiation and propagation phenotypes of renal cell carcinoma cells by activating Akt and sonic hedgehog axes
-
Cao, Y., Wang, L., Nandy, D., Zhang, Y., Basu, A., Radisky, D., and Mukhopadhyay, D. (2008) Neuropilin-1 upholds dedifferentiation and propagation phenotypes of renal cell carcinoma cells by activating Akt and sonic hedgehog axes. Cancer Res. 68, 8667-8672
-
(2008)
Cancer Res
, vol.68
, pp. 8667-8672
-
-
Cao, Y.1
Wang, L.2
Nandy, D.3
Zhang, Y.4
Basu, A.5
Radisky, D.6
Mukhopadhyay, D.7
-
100
-
-
84886592079
-
Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma
-
Hayden Gephart, M. G., Su, Y. S., Bandara, S., Tsai, F. C., Hong, J., Conley, N., Rayburn, H., Milenkovic, L., Meyer, T., and Scott, M. P. (2013) Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma. J. Neurooncol. 115, 161-168
-
(2013)
J. Neurooncol
, vol.115
, pp. 161-168
-
-
Hayden Gephart, M.G.1
Su, Y.S.2
Bandara, S.3
Tsai, F.C.4
Hong, J.5
Conley, N.6
Rayburn, H.7
Milenkovic, L.8
Meyer, T.9
Scott, M.P.10
|