Predicting pharmacodynamic drug-drug interactions through signaling propagation interference on protein-protein interaction networks

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Park, Kyunghyun ^a   Kim, Docyong ^a   Ha, Suhyun ^a   Lee, Doheon ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; OLANZAPINE; QUETIAPINE; ZIPRASIDONE; PLACEBO;

ACCESS TO INFORMATION; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; COMPUTER PROGRAM; COMPUTER SIMULATION; DRUG INTERACTION; DRUG TARGETING; INTERMETHOD COMPARISON; INTERNET; MATHEMATICAL ANALYSIS; PHARMACODYNAMICS; PREDICTION; PROBABILITY; PROTEIN PROTEIN INTERACTION; RECEIVER OPERATING CHARACTERISTIC; SIGNAL TRANSDUCTION; ALGORITHM; COMPARATIVE STUDY; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; EVALUATION STUDY; HUMAN; METABOLISM; PHARMACOKINETICS; PROCEDURES; PROTEIN ANALYSIS; PROTEIN DATABASE;

ALGORITHMS; DATABASES, PROTEIN; DRUG INTERACTIONS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; HUMANS; PHARMACOKINETICS; PLACEBOS; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS;

EID: 84948955378     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140816     Document Type: Article

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