메뉴 건너뛰기




Volumn 13, Issue SUPPL1, 2013, Pages

Rule-based multi-scale simulation for drug effect pathway analysis

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

EID: 84875921750     PISSN: None     EISSN: 14726947     Source Type: Journal    
DOI: 10.1186/1472-6947-13-S1-S4     Document Type: Article
Times cited : (14)

References (28)
  • 1
    • 84855906454 scopus 로고    scopus 로고
    • Systems pharmacology: Network analysis to identify multiscale mechanisms of drug action
    • 10.1146/annurev-pharmtox-010611-134520 22235860
    • Systems pharmacology: network analysis to identify multiscale mechanisms of drug action. Zhao S, Iyengar R, Annual review of pharmacology and toxicology 2012 52 505 521 10.1146/annurev-pharmtox-010611-134520 22235860
    • (2012) Annual Review of Pharmacology and Toxicology , vol.52 , pp. 505-521
    • Zhao, S.1    Iyengar, R.2
  • 2
    • 5044226336 scopus 로고    scopus 로고
    • Systems biology in drug discovery
    • 10.1038/nbt1017 15470465
    • Systems biology in drug discovery. Butcher EC, Berg EL, Kunkel EJ, Nature biotechnology 2004 22 10 1253 1259 10.1038/nbt1017 15470465
    • (2004) Nature Biotechnology , vol.22 , Issue.10 , pp. 1253-1259
    • Butcher, E.C.1    Berg, E.L.2    Kunkel, E.J.3
  • 3
    • 84855882587 scopus 로고    scopus 로고
    • Novel computational approaches to polypharmacology as a means to define responses to individual drugs
    • 10.1146/annurev-pharmtox-010611-134630 22017683
    • Novel computational approaches to polypharmacology as a means to define responses to individual drugs. Xie L, Kinnings SL, Bourne PE, Annual review of pharmacology and toxicology 2012 52 361 379 10.1146/annurev-pharmtox-010611- 134630 22017683
    • (2012) Annual Review of Pharmacology and Toxicology , vol.52 , pp. 361-379
    • Xie, L.1    Kinnings, S.L.2    Bourne, P.E.3
  • 4
    • 67049100457 scopus 로고    scopus 로고
    • Drug discovery using chemical systems biology: Identification of the protein-ligand binding network to explain the side effects of CETP inhibitors
    • 10.1371/journal.pcbi.1000387 19436720
    • Drug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitors. Xie L, Li J, Bourne PE, PLoS computational biology 2009 5 5 1000387 10.1371/journal.pcbi.1000387 19436720
    • (2009) PLoS Computational Biology , vol.5 , Issue.5 , pp. 51000387
    • Xie, L.1    Li, J.2    Bourne, P.E.3
  • 5
    • 60449115552 scopus 로고    scopus 로고
    • The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
    • 10.1016/j.mvr.2008.08.003 18805433
    • The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions. Lu L, Payvandi F, Wu L, Zhang LH, Hariri RJ, Man HW, Chen RS, Muller GW, Hughes CC, Stirling DI, et al. Microvascular research 2009 77 2 78 86 10.1016/j.mvr.2008.08.003 18805433
    • (2009) Microvascular Research , vol.77 , Issue.2 , pp. 78-86
    • Lu, L.1    Payvandi, F.2    Wu, L.3    Zhang, L.H.4    Hariri, R.J.5    Man, H.W.6    Chen, R.S.7    Muller, G.W.8    Hughes, C.C.9    Stirling, D.I.10
  • 6
    • 35148824614 scopus 로고    scopus 로고
    • Network pharmacology
    • 10.1038/nbt1007-1110 17921993
    • Network pharmacology. Hopkins AL, Nature biotechnology 2007 25 10 1110 1111 10.1038/nbt1007-1110 17921993
    • (2007) Nature Biotechnology , vol.25 , Issue.10 , pp. 1110-1111
    • Hopkins, A.L.1
  • 8
    • 33749011163 scopus 로고    scopus 로고
    • The NCI60 human tumour cell line anticancer drug screen
    • 10.1038/nrc1951 16990858
    • The NCI60 human tumour cell line anticancer drug screen. Shoemaker RH, Nature reviews Cancer 2006 6 10 813 823 10.1038/nrc1951 16990858
    • (2006) Nature Reviews Cancer , vol.6 , Issue.10 , pp. 813-823
    • Shoemaker, R.H.1
  • 9
    • 70049113642 scopus 로고    scopus 로고
    • Optimal drug combinations and minimal hitting sets
    • 10.1186/1752-0509-3-81 19660129
    • Optimal drug combinations and minimal hitting sets. Vazquez A, BMC systems biology 2009 3 81 10.1186/1752-0509-3-81 19660129
    • (2009) BMC Systems Biology , vol.3 , pp. 81
    • Vazquez, A.1
  • 10
    • 79960047322 scopus 로고    scopus 로고
    • Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles
    • 10.1186/1752-0509-5-109 21745399
    • Simulating quantitative cellular responses using asynchronous threshold Boolean network ensembles. Jack J, Wambaugh JF, Shah I, BMC systems biology 2011 5 109 10.1186/1752-0509-5-109 21745399
    • (2011) BMC Systems Biology , vol.5 , pp. 109
    • Jack, J.1    Wambaugh, J.F.2    Shah, I.3
  • 11
    • 79959473110 scopus 로고    scopus 로고
    • An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data
    • 10.1093/bioinformatics/btr202 21685086
    • An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data. Jin G, Zhao H, Zhou X, Wong ST, Bioinformatics 2011 27 13 310 316 10.1093/bioinformatics/btr202 21685086
    • (2011) Bioinformatics , vol.27 , Issue.13 , pp. 9310-9316
    • Jin, G.1    Zhao, H.2    Zhou, X.3    Wong, S.T.4
  • 13
    • 78649842241 scopus 로고    scopus 로고
    • Genomics, type 2 diabetes, and obesity
    • 10.1056/NEJMra0906948 21142536
    • Genomics, type 2 diabetes, and obesity. McCarthy MI, The New England journal of medicine 2010 363 24 2339 2350 10.1056/NEJMra0906948 21142536
    • (2010) The New England Journal of Medicine , vol.363 , Issue.24 , pp. 2339-2350
    • McCarthy, M.I.1
  • 17
    • 20144385752 scopus 로고    scopus 로고
    • Rule-based modeling of biochemical networks
    • 10.1002/cplx.20074
    • Rule-based modeling of biochemical networks. Faeder JR, Blinov ML, Goldstein B, Hlavacek WS, Complexity 2005 10 4 22 41 10.1002/cplx.20074
    • (2005) Complexity , vol.10 , Issue.4 , pp. 22-41
    • Faeder, J.R.1    Blinov, M.L.2    Goldstein, B.3    Hlavacek, W.S.4
  • 21
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • 10.1038/nature05482 17167471
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes. Kahn SE, Hull RL, Utzschneider KM, Nature 2006 444 7121 840 846 10.1038/nature05482 17167471
    • (2006) Nature , vol.444 , Issue.7121 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 22
    • 39749147110 scopus 로고    scopus 로고
    • Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes
    • 10.1038/nrm2327 18200017
    • Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Muoio DM, Newgard CB, Nature reviews Molecular cell biology 2008 9 3 193 205 10.1038/nrm2327 18200017
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.3 , pp. 193-205
    • Muoio, D.M.1    Newgard, C.B.2
  • 23
    • 84855603512 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of metformin: An overview
    • 10.1042/CS20110386 22117616
    • Cellular and molecular mechanisms of metformin: an overview. Viollet B, Guigas B, Sanz Garcia N, Leclerc J, Foretz M, Andreelli F, Clin Sci (Lond) 2012 122 6 253 270 10.1042/CS20110386 22117616
    • (2012) Clin Sci (Lond) , vol.122 , Issue.6 , pp. 253-270
    • Viollet, B.1    Guigas, B.2    Sanz Garcia, N.3    Leclerc, J.4    Foretz, M.5    Andreelli, F.6
  • 24
    • 84860430319 scopus 로고    scopus 로고
    • Discovering context-specific relationships from biological literature by using multi-level context terms
    • 10.1186/1472-6947-12-S1-S1 22595086
    • Discovering context-specific relationships from biological literature by using multi-level context terms. Lee S, Choi J, Park K, Song M, Lee D, BMC Medical Informatics and Decision Making 2012 12 Suppl 1 1 10.1186/1472-6947-12- S1-S1 22595086
    • (2012) BMC Medical Informatics and Decision Making , vol.12 , Issue.SUPPL. 1 , pp. 191
    • Lee, S.1    Choi, J.2    Park, K.3    Song, M.4    Lee, D.5
  • 26
    • 0035374524 scopus 로고    scopus 로고
    • The synergistic effect of miglitol plus metformin combination therapy in the treatment of type 2 diabetes
    • 10.2337/diacare.24.6.989 11375358
    • The synergistic effect of miglitol plus metformin combination therapy in the treatment of type 2 diabetes. Chiasson JL, Naditch L, Diabetes care 2001 24 6 989 994 10.2337/diacare.24.6.989 11375358
    • (2001) Diabetes Care , vol.24 , Issue.6 , pp. 989-994
    • Chiasson, J.L.1    Naditch, L.2
  • 27
    • 60249095597 scopus 로고    scopus 로고
    • Safety and efficacy of nateglinide/metformin combination therapy in the treatment of type 2 diabetes
    • 19337530
    • Safety and efficacy of nateglinide/metformin combination therapy in the treatment of type 2 diabetes. Israel MK, Istvan E, Baron MA, Vascular health and risk management 2008 4 6 1167 1178 19337530
    • (2008) Vascular Health and Risk Management , vol.4 , Issue.6 , pp. 1167-1178
    • Israel, M.K.1    Istvan, E.2    Baron, M.A.3
  • 28
    • 34548311750 scopus 로고    scopus 로고
    • Effects of pioglitazone in combination with metformin or a sulfonylurea compared to a fixed-dose combination of metformin and glibenclamide in patients with type 2 diabetes
    • 10.1089/dia.2006.0023 17705695
    • Effects of pioglitazone in combination with metformin or a sulfonylurea compared to a fixed-dose combination of metformin and glibenclamide in patients with type 2 diabetes. Comaschi M, Demicheli A, Di Pietro C, Bellatreccia A, Mariz S, Diabetes technology & therapeutics 2007 9 4 387 398 10.1089/dia.2006.0023 17705695
    • (2007) Diabetes Technology & Therapeutics , vol.9 , Issue.4 , pp. 387-398
    • Comaschi, M.1    Demicheli, A.2    Di Pietro, C.3    Bellatreccia, A.4    Mariz, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.