Protective role of edaravone against cisplatin-induced ototoxicity in an auditory cell line

Hearing Research

Volumn 330, Issue , 2015, Pages 113-118

  Im, Gi Jung ^a   Chang, Jiwon ^b   Lee, Sehee ^a   Choi, June ^a   Jung, Hak Hyun ^a   Lee, Hyung Min ^b   Ryu, Sung Hoon ^b   Park, Su Kyoung ^b   Kim, Jin Hwan ^b   Kim, Hyung Jong ^b  

^a Korea University College of Medicine   (South Korea)

^b Hallym University College of Medicine   (South Korea)

Author keywords

Apoptosis; Cell culture; Cisplatin; Edaravone; Ototoxicity

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 3; CISPLATIN; FREE RADICAL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NORPHENAZONE; REACTIVE OXYGEN METABOLITE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CASP3 PROTEIN, MOUSE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PARP1 PROTEIN, MOUSE; PHENAZONE; PHENYLMETHYLPYRAZOLONE; SCAVENGER;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AUDITORY SYSTEM; CELL LINE; CELL PROLIFERATION ASSAY; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEI OC1 CELL; IMMUNOBLOTTING; INCUBATION TIME; MTT ASSAY; NEUROPROTECTION; NONHUMAN; OTOTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHEMICALLY INDUCED; COCHLEAR HAIR CELL; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; HEARING; HEARING IMPAIRMENT; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; ANTIPYRINE; APOPTOSIS; CASPASE 3; CELL LINE; CELL SURVIVAL; CISPLATIN; FREE RADICAL SCAVENGERS; HAIR CELLS, AUDITORY; HEARING; HEARING LOSS; IMMUNOBLOTTING; MICE; MICROSCOPY, FLUORESCENCE; POLY (ADP-RIBOSE) POLYMERASE-1; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES;

EID: 84948766014     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2015.08.004     Document Type: Article

References (29)

1. Asplund M.S., Lidian A., Linder B., Takumida M., Anniko M. Protective effect of edaravone against tobramycin-induced ototoxicity. Acta Otolaryngol. 2009, 129(2009):8-13.
2. Bánfi B., Malgrange B., Knisz J., Steger K., Dubois-Dauphin M., Krause K.-H. NOX3, a superoxide-generating NADPH oxidase of the inner ear. J. Biol. Chem. 2004, 279:46065-47232.
3. Campbell K.C., Meech R.P., Rybak L.P., Hughes L.F. The effect of D-methionine on cochlear oxidative state with and without cisplatin administration: mechanisms of otoprotection. J. Am. Acad. Audiol. 2003, 14(3):144-156.
4. Casares C., Ramírez-Camacho R., Trinidad A., Roldán A., Jorge E., García-Berrocal J.R. Reactive oxygen species in apoptosis induced by cisplatin: review of physiopathological mechanisms in animal models. Eur. Arch. Otorhinolaryngol. 2012, 269(12):2455-2459.
5. Chang J., Jung H.H., Yang J.Y., Lee S., Choi J., Im G.J., Chae S.W. Protective effect of metformin against cisplatin-induced ototoxicity in an auditory cell line. J. Assoc. Res. Otolaryngol. 2014, 15(2):149-158.
6. Choe W.T., Chinosornvatana N., Chang W.K. Prevention of cisplatin ototoxicity using transtympanic N-acetylcysteine and lactate. Otol. Neurotol. 2004, 25:910-915.
7. Dickey T.D., Mulcoon L.L., Kraemer D.F., Neuwelt E.A. Protection against cisplatin induced ototoxicity by N-acetyl-cysteine in rat model. Hear Res. 2004, 193:25-30.
8. Gutteridge J.M., Halliwell B. Antioxidants: molecules, medicines and myths. Biochem. Biophys. Res. Commun. 2010, 393(4):561-564.
9. Higashi Y., Jitsuiki D., Chayama K., Yoshizumi M. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases. Recent Pat. Cardiovasc Drug Discov. 2006, 1(1):85-93.
10. Hong S.J., Im G.J., Chang J., Chae S.W., Lee S.H., Kwon S.Y., Jung H.H., Chung A.Y., Park H.C., Choi J. Protective effects of edaravone against cisplatin-induced hair cell damage in zebrafish. Int. J. Pediatr. Otorhinolaryngol. 2013, 77(6):1025-1031.
11. Horiike O., Shimogori H., Ikeda T., Yamashita H. Protective effect of edaravone against streptomycin-induced vestibulotoxicity in the guinea pig. Eur. J. Pharmacol. 2003, 464:75-78.
12. Ikeda K., Sunose H., Takasaka T. Effects of free radicals on the intracellular calcium concentration in the isolated hair cell of the guinea pig cochlea. Acta Otolaryngol. 1993, 113:137-141.
13. Kalinec G.M., Webster P., Lim D.J., Kalinec F. A cochlear cell line as an in vitro system for drug ototoxicity screening. Audiol. Neurootol. 2003, 8:177-189.
14. Kim J., Cho H.J., Sagong B., Kim S.J., Lee J.T., So H.S., Lee I.K., Kim U.K., Lee K.Y., Choo Y.S. Alpha-lipoic acid protects against cisplatin-induced ototoxicity via the regulation of MAPKs and proinflammatory cytokines. Biochem. Biophys. Res. Commun. 2014, 449(2):183-189.
15. Lee M.K., Kang S.J., Poncz M., Sibg K.J., Park K.S. Resveratrol protects SH-SY5Y neuroblastoma cells from apoptosis induced by dopamine. Exp. Mol. Med. 2007, 39(3):376-384.
16. Maekawa H., Matsunobu T., Tsuda H., Onozato K., Masuda Y., Tanabe T., Shiotani A. Therapeutic effect of edaravone on inner ear barotrauma in the guinea pig. Neurochem. Int. 2009, 54:513-518.
17. McKeage M.J. Comparative adverse effect profiles of platinum drugs. Drug Saf. 1995, 13:228-244.
18. Mishina M., Komaba Y., Kobayashi S., Tanaka N., Kominami S., Fukuchi T., et al. Efficacy of edaravone, a free radical scavenger, for the treatment of acute lacunar infarction. Neurol. Med. Chir. (Tokyo) 2005, 45:344-348. discussion 348.
19. Pigeolet E., Corbisier P., Houbion A., Lambert D., Michiels C., Raes M., et al. Glutathione peroxidase, superoxide dismutase and catalase inactivation by peroxides and oxygen derived free radicals. Mech. Ageing Dev. 1990, 50:283-297.
20. Roland J.T., Cohen N.L. Vestibular and auditory ototoxicity. Otolaryngology & Head and Neck Surgery 1998, Mosby, St. Louis, 3186e3197. third ed. C.W. Cummings, J.M. Frederickson, L.A. Harker, C.J. Krause, D.F. Schuller, M.A. Richardson (Eds.).
21. Rybak L.P. Mechanisms of cisplatin ototoxicity and progress in otoprotection. Curr. Opin. Otolaryngol. Head. Neck Surg. 2007, 15:364-369.
22. Rybak L.P., Mukherjea D., Jajoo S., Ramkumar V. Cisplatin ototoxicity and protection: clinical and experimental studies. Tohoku J. Exp. Med. 2009, 219:177-186.
23. Saleh S., El-Demerdash E. Protective effects of L-arginine against cisplatin-induced renal oxidative stress and toxicity: role nitric oxide. Basic Clin. Pharmacol. Toxicol. 2005, 97:91-97.
24. Takemoto T., Sugahara K., Okuda T., Shimogori H., Yamashita H. The clinical free radical scavenger, edaravone, protects cochlear hair cells from acoustic trauma. Eur. J. Pharmaology 2004, 487:113-116.
25. Takumida M., Anniko M. Protective effect of edaravone against the ototoxicity of Pseudomonas aeruginosa exotoxin A. Acta Otolaryngol. 2006, 126(1):15-19.
26. Tsujita K., Shimomura H., Kawano H., Hokamaki J., Fukuda M., Yamashita T., et al. Effects of edaravone on reperfusion injury in patients with acute myocardial infarction. Am. J. Cardiol. 2004, 94:481-484.
27. Wang D., Lippard S.J. Cellular processing of platinum anticancer drugs. Nat. Rev. Drug Discov. 2005, 4:307-320.
28. Wang J., Lloyd Faulconbridge R.V., Fetoni A., Guitton M.J., Pujol R., Puel J.L. Local application of sodium thiosulfate prevents cisplatin-induced hearing loss in the guinea pig. Neuropharmacology 2003, 45(3):380-393.
29. Watanabe T., Morita I., Nishi H., Murota S. Preventive effect of MCI-186 on 15-HPETE induced vascular endothelial cell injury in vitro. Prostagl. Leukot. Essent. Fat. Acids 1988, 33(1):81-87.