Protective effect of metformin against cisplatin-induced ototoxicity in an auditory cell line

JARO - Journal of the Association for Research in Otolaryngology

Volumn 15, Issue 2, 2014, Pages 149-158

  Chang, Jiwon ^a   Jung, Hak Hyun ^a   Yang, Ji Yoon ^a   Lee, Sehee ^a   Choi, June ^a   Im, Gi Jung ^a   Chae, Sung Won ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

calcium imaging; cell culture; cisplatin; metformin; ototoxicity

Indexed keywords

3 (4,5 DIMETHYLTHIAZOL 2 YL) 2,5 DIPHENYLTETRAZOLIUMBROMIDE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; BROMIDE; CASPASE 3; CISPLATIN; METFORMIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CALCIUM;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL LINE; CELL PROLIFERATION ASSAY; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FLOW CYTOMETRY; OTOTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; WESTERN BLOTTING; ANIMAL; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; HAIR CELL; METABOLISM; MOUSE; TOXICITY;

ANIMALS; ANTINEOPLASTIC AGENTS; CALCIUM; CASPASE 3; CELL LINE; CELL SURVIVAL; CISPLATIN; CYTOPROTECTION; HAIR CELLS, AUDITORY; METFORMIN; MICE; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES;

EID: 84897021769     PISSN: 15253961     EISSN: 14387573     Source Type: Journal    
DOI: 10.1007/s10162-013-0431-y     Document Type: Article

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