Running for your life: A review of physical activity and cardiovascular disease risk reduction in individuals with schizophrenia

Journal of Sports Sciences

Volumn 34, Issue 16, 2016, Pages 1500-1515

  Chalfoun, Claire ^a   Karelis, Antony D ^b   Stip, Emmanuel ^a,c   Abdel Baki, Amal ^a,c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Aerobic interval training; Cardiorespiratory fitness; Metabolic complications; Non pharmacological interventions; Psychosis

Indexed keywords

NEUROLEPTIC AGENT;

CARDIORESPIRATORY FITNESS; CARDIOVASCULAR DISEASES; COMPLICATION; EXERCISE; HUMAN; PATHOPHYSIOLOGY; RISK FACTOR; SCHIZOPHRENIA;

ANTIPSYCHOTIC AGENTS; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR DISEASES; EXERCISE; HUMANS; PHYSICAL CONDITIONING, HUMAN; RISK FACTORS; SCHIZOPHRENIA;

EID: 84948745343     PISSN: 02640414     EISSN: 1466447X     Source Type: Journal    
DOI: 10.1080/02640414.2015.1119875     Document Type: Review

References (87)

1. Abdel-Baki, A., Brazzini-Poisson, V., Marois, F., Letendre, E., & Karelis, A. D. (2013). Effects of aerobic interval training on metabolic complications and cardiorespiratory fitness in young adults with psychotic disorders: A pilot study. Schizophrenia Research, 149(1-3), 112-115.
2. Addington, J., Mansley, C., & Addington, D. (2003). Weight gain in firstepisode psychosis. Canadian Journal of Psychiatry, 48(4), 272-276.
3. Alvarez-Jimenez, M., Hetrick, S. E., Gonzalez-Blanch, C., Gleeson, J. F., & McGorry, P. D. (2008). Non-pharmacological management of antipsychotic-induced weight gain: Systematic review and meta-analysis of randomised controlled trials. British Journal of Psychiatry, 193(2), 101-107.
4. Ball, M. P., Coons, V. B., & Buchanan, R. W. (2001). A program for treating olanzapine-related weight gain. Psychiatric Services, 52(7), 967-969.
5. Bassilios, B., Judd, F., Pattison, P., Nicholas, A., & Moeller-Saxone, K. (2015). Predictors of exercise in individuals with schizophrenia: A test of the transtheoretical model of behavior change. Clinical Schizophrenia & Related Psychoses, 8(4), 173-182, 182A.
6. Battaglia, G., Alesi, M., Inguglia, M., Roccella, M., Caramazza, G., Bellafiore, M., & Palma, A. (2013). Soccer practice as an add-on treatment in the management of individuals with a diagnosis of schizophrenia. Neuropsychiatric Disease and Treatment, 9, 595-603.
7. Beebe, L. H. (2008). Obesity in schizophrenia: Screening, monitoring, and health promotion. Perspective Psychiatric Care, 44(1), 25-31.
8. Beebe, L. H., Burk, R., McIntyre, K., Smith, K., Velligan, D., Resnick, B., Dessieux, O. (2009). Motivating persons with schizophrenia spectrum disorders to exercise: Rationale and design. Clinical Schizophrenia & Related Psychoses, 3(2), 111-116.
9. Beebe, L. H., Tian, L., Morris, N., Goodwin, A., Allen, S. S., & Kuldau, J. (2005). Effects of exercise on mental and physical health parameters of persons with schizophrenia. Issues in Mental Health Nursing, 26(6), 661-676.
10. Bernard, P., & Ninot, G. (2012). Benefits of exercise for people with schizophrenia: A systematic review. Encephale, 38(4), 280-287.
11. Bradshaw, T., Lovell, K., & Harris, N. (2005). Healthy living interventions and schizophrenia: A systematic review. Journal of Advanced Nursing, 49(6), 634-654.
12. Cabassa, L. J., Ezell, J. M., & Lewis-Fernandez, R. (2010). Lifestyle interventions for adults with serious mental illness: A systematic literature review. Psychiatric Services, 61(8), 774-782.
13. Caemmerer, J., Correll, C. U., & Maayan, L. (2012). Acute and maintenance effects of non-pharmacologic interventions for antipsychotic associated weight gain and metabolic abnormalities: A meta-analytic comparison of randomized controlled trials. Schizophrenia Research, 140(1-3), 159-168.
14. Cimo, A., Stergiopoulos, E., Cheng, C., Bonato, S., & Dewa, C. S. (2012). Effective lifestyle interventions to improve type II diabetes self-management for those with schizophrenia or schizoaffective disorder: A systematic review. BMC Psychiatry, 12(1), 24.
15. Das, C., Mendez, G., Jagasia, S., & Labbate, L. A. (2012). Second-generation antipsychotic use in schizophrenia and associated weight gain: A critical review and meta-analysis of behavioral and pharmacologic treatments. Annals of Clinical Psychiatry, 24(3), 225-239.
16. Daumit, G. L., Dickerson, F. B., Wang, N.-Y., Dalcin, A., Jerome, G. J., Anderson, C. A. M., Appel, L. J. (2013). A behavioral weight-loss intervention in persons with serious mental illness. New England Journal of Medicine, 368(17), 1594-1602.
17. Daussin, F. N., Zoll, J., Dufour, S. P., Ponsot, E., Lonsdorfer-Wolf, E., Doutreleau, S., & Richard, R. (2008). Effect of interval versus continuous training on cardiorespiratory and mitochondrial functions: Relationship to aerobic performance improvements in sedentary subjects. American Journal of Physiology: Regulative Integrative and Comparative Physiology, 295(1), R264-272.
18. De Hert, M., Detraux, J., Van Winkel, R., Yu, W., & Correll, C. U. (2011). Metabolic and cardiovascular adverse effects associated with antipsychotic drugs. Nature Reviews Endocrinology, 8(2), 114-126.
19. De Hert, M., Dobbelaere, M., Sheridan, E. M., Cohen, D., & Correll, C. U. (2011). Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: A systematic review of randomized, placebo controlled trials and guidelines for clinical practice. European Psychiatry, 26(3), 144-158.
20. De Hert, M., Schreurs, V., Vancampfort, D., & VAN Winkel, R. (2009). Metabolic syndrome in people with schizophrenia: A review. World Psychiatry, 8(1), 15-22.
21. Dellal, A., Varliette, C., Owen, A., Chirico, E. N., & Pialoux, V. (2012). Smallsided games versus interval training in amateur soccer players: Effects on the aerobic capacity and the ability to perform intermittent exercises with changes of direction. Journal of Strength and Conditioning Research, 26(10), 2712-2720.
22. Faulkner, G., Cohn, T., & Remington, G. (2007). Interventions to reduce weight gain in schizophrenia. Schizophrenia Bulletin, 33(3), 654-656.
23. Fex, A., Leduc-Gaudet, J. P., Filion, M. E., Karelis, A. D., & Aubertin-Leheudre, M. (2014). Effect of elliptical high intensity interval training on metabolic risk factor in pre-and type 2 diabetes patients: A pilot study. Journal of Physical Activity & Health. doi:10.1123/jpah.2014-0123
24. Filik, R., Sipos, A., Kehoe, P. G., Burns, T., Cooper, S. J., Stevens, H., Harrison, G. (2006). The cardiovascular and respiratory health of people with schizophrenia. Acta Psychiatrica Scandinavica, 113(4), 298-305.
25. Fogarty, M., & Happell, B. (2005). Exploring the benefits of an exercise program for people with schizophrenia: A qualitative study. Issues in Mental Health Nursing, 26(3), 341-351.
26. Gabriele, J. M., Dubbert, P. M., & Reeves, R. R. (2009). Efficacy of behavioural interventions in managing atypical antipsychotic weight gain. Obesity Reviews, 10(4), 442-455.
27. Ganguli, R. (2007). Behavioral therapy for weight loss in patients with schizophrenia. Journal of Clinical Psychiatry, 68 (Suppl 4), 19-25.
28. Gebhardt, S., Theisen, F. M., Haberhausen, M., Heinzel-Gutenbrunner, M., Wehmeier, P. M., Krieg, J.-C., Hebebrand, J. (2010). Body weight gain induced by atypical antipsychotics: An extension of the monocygotic twin and sib pair study. Journal of Clinical Pharmacy and Therapeutics, 35(2), 207-211.
29. Ghanizadeh, A., Nikseresht, M. S., & Sahraian, A. (2013). The effect of zonisamide on antipsychotic-associated weight gain in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial. Schizophrenia Research, 147(1), 110-115.
30. Gibala, M. J., & McGee, S. L. (2008). Metabolic adaptations to short-term high-intensity interval training: A little pain for a lot of gain? Exercise and Sport Sciences Reviews, 36(2), 58-63.
31. Goodpaster, B. H., Katsiaras, A., & Kelley, D. E. (2003). Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity. Diabetes, 52(9), 2191-2197.
32. Gorczynski, P., & Faulkner, G. (2010). Exercise therapy for schizophrenia. Cochrane Database of Systematic Reviews, 12(5), CD004412.
33. Grundy, S. M., Brewer, H. B., Jr., Cleeman, J. I., Smith, S. C., Jr., & Lenfant, C. (2004). Definition of metabolic syndrome: Report of the national heart, lung, and blood institute/American heart association conference on scientific issues related to definition. Circulation, 109(3), 433-438.
34. Grundy, S. M., Brewer, H. B., Jr., Cleeman, J. I., Smith, S. C., Jr., Lenfant, C., National Heart, L., & American Heart, A. (2004). Definition of metabolic syndrome: Report of the national heart, lung, and blood institute/ American heart association conference on scientific issues related to definition. Arteriosclerosis, Thrombosis and Vascular Biology, 24(2), e13-18.
35. Gupta, A., & Gupta, V. (2010). Metabolic syndrome: What are the risks for humans? Bioscience Trends, 4(5), 204-212.
36. Hansen, T., Ingason, A., Djurovic, S., Melle, I., Fenger, M., Gustafsson, O., Werge, T. (2011). At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia. Biological Psychiatry, 70(1), 59-63.
37. Heggelund, J., Nilsberg, G. E., Hoff, J., Morken, G., & Helgerud, J. (2011). Effects of high aerobic intensity training in patients with schizophrenia —A controlled trial. Nordic Journal of Psychiatry, 65(4), 269-275.
38. Herbsleb, M., Muhlhaus, T., & Bar, K. J. (2014). Differential cardiac effects of aerobic interval training versus moderate continuous training in a patient with schizophrenia: A case report. Frontiers in Psychiatry, 5, 119.
39. Huang, T. L., & Chen, J. F. (2005). Serum lipid profiles and schizophrenia: Effects of conventional or atypical antipsychotic drugs in Taiwan. Schizophrenia Research, 80(1), 55-59.
40. Hwang, C. L., Wu, Y. T., & Chou, C. H. (2011). Effect of aerobic interval training on exercise capacity and metabolic risk factors in people with cardiometabolic disorders: A meta-analysis. Journal of Cardiopulmonary Rehabilitation and Prevention, 31(6), 378-385.
41. Johnson, J. L., Slentz, C. A., Houmard, J. A., Samsa, G. P., Duscha, B. D., Aiken, L. B., Kraus, W. E. (2007). Exercise training amount and intensity effects on metabolic syndrome (from studies of a targeted risk reduction intervention through defined exercise). The American Journal of Cardiology, 100(12), 1759-1766.
42. Kessler, H. S., Sisson, S. B., & Short, K. R. (2012). The potential for highintensity interval training to reduce cardiometabolic disease risk. Sports Medicine, 42(6), 489-509.
43. Kodama, S., Saito, K., Tanaka, S., Maki, M., Yachi, Y., Asumi, M., Sone, H. (2009). Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: A meta-analysis. Journal of the American Medical Association, 301(19), 2024-2035.
44. Krogh, J., Speyer, H., Norgaard, H. C., Moltke, A., & Nordentoft, M. (2014). Can exercise increase fitness and reduce weight in patients with schizophrenia and depression? Frontiers in Psychiatry, 5, 89.
45. Kuo, F. C., Lee, C. H., Hsieh, C. H., Kuo, P., Chen, Y. C., & Hung, Y. J. (2012). Lifestyle modification and behavior therapy effectively reduce body weight and increase serum level of brain-derived neurotrophic factor in obese non-diabetic patients with schizophrenia. Psychiatry Research, 209(2), 150-154.
46. Lieberman, J., Stroup, S., & Perkins, D. (2006). The American psychiatric publishing textbook of schizophrenia (1st ed.). Washington, DC: American Psychiatric Pub.
47. Little, J. P., Safdar, A., Bishop, D., Tarnopolsky, M. A., & Gibala, M. J. (2011). An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1alpha and activates mitochondrial biogenesis in human skeletal muscle. American Journal of Physiology: Regulatory Integrative Comparatrive Physiology, 300(6), R1303-1310.
48. Loh, C., Meyer, J. M., & Leckband, S. G. (2006). A comprehensive review of behavioral interventions for weight management in schizophrenia. Annals of Clinical Psychiatry, 18(1), 23-31.
49. Maayan, L., & Correll, C. U. (2010). Management of antipsychotic-related weight gain. Expert Review of Neurotherapeutics, 10(7), 1175-1200.
50. Maayan, L., Vakhrusheva, J., & Correll, C. U. (2010). Effectiveness of medications used to attenuate antipsychotic-related weight gain and metabolic abnormalities: A systematic review and meta-analysis. Neuropsychopharmacology, 35(7), 1520-1530.
51. Marzolini, S., Jensen, B., & Melville, P. (2009). Feasibility and effects of a group-based resistance and aerobic exercise program for individuals with severe schizophrenia: A multidisciplinary approach. Mental Health and Physical Activity, 2(1), 29-36.
52. Messier, V., Brazeau, A. S., Rabasa-Lhoret, R., & Karelis, A. D. (2011). Physical exercise in the prevention and treatment of obesity, diabetes and metabolic syndrome. In M. Mancini (Ed.), Nutritional and metabolic bases of cardiovascular disease. Chichester: Wiley-Blackwell.
53. Mukundan, A., Faulkner, G., Cohn, T., & Remington, G. (2010). Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems. Cochrane Database of Systematic Reviews, 8(12), CD006629.
54. Myers, J., Prakash, M., Froelicher, V., Do, D., Partington, S., & Atwood, J. E. (2002). Exercise capacity and mortality among men referred for exercise testing. New England Journal of Medicine, 346(11), 793-801.
55. Nemoto, K., Gen-no, H., Masuki, S., Okazaki, K., & Nose, H. (2007). Effects of highintensity interval walking training on physical fitness and blood pressure in middle-aged and older people. Mayo Clinic Proceedings, 82(7), 803-811.
56. Newcomer, J. W., & Hennekens, C. H. (2007). Severe mental illness and risk of cardiovascular disease. Journal of the American Medical Association, 298(15), 1794-1796.
57. Nilsson, B. B., Westheim, A., & Risberg, M. A. (2008). Effects of group-based high-intensity aerobic interval training in patients with chronic heart failure. The American Journal of Cardiology, 102(10), 1361-1365.
58. Nyboe, L., & Lund, H. (2013). Low levels of physical activity in patients with severe mental illness. Nordic Journal of Psychiatry, 67(1), 43-46.
59. Ohlsen, R., Treasure, J., & Pilowsky, L. (2004). Behavioral management of antipsychotic-induced weight gain. Acta Psychiatrica Scandanavica, 109 (2), 156; author reply 156.
60. Pajonk, F.-G., Wobrock, T., Gruber, O., Scherk, H., Berner, D., Kaizl, I., Falkai, P. (2010). Hippocampal plasticity in response to exercise in schizophrenia. Archives of General Psychiatry, 67(2), 133-143.
61. Papanastasiou, E. (2012). Interventions for the metabolic syndrome in schizophrenia: A review. Therapeutic Advances in Endocrinology and Metabolism, 3(5), 141-162.
62. Pelham, T. W., Campagna, P. D., Ritvo, P. G., & Birnie, W. A. (1993). The effects of exercise therapy on clients in a psychiatric rehabilitation program. Psychosocial Rehabilitation Journal, 16(4), 75-84.
63. Poulin, M.-J., Chaput, J.-P., Simard, V., Vincent, P., Bernier, J., Gauthier, Y., Tremblay, A. (2007). Management of antipsychotic-induced weight gain: Prospective naturalistic study of the effectiveness of a supervised exercise programme. Australian and New Zealand Journal of Psychiatry, 41(12), 980-989.
64. Rastad, C., Martin, C., & Asenlof, P. (2014). Barriers, benefits, and strategies for physical activity in patients with schizophrenia. Physical Therapy, 94 (10), 1467-1479.
65. Ratliff, J. C., Palmese, L. B., Reutenauer, E. L., Liskov, E., Grilo, C. M., & Tek, C. (2012). The effect of dietary and physical activity pattern on metabolic profile in individuals with schizophrenia: A cross-sectional study. Comprehensive Psychiatry, 53(7), 1028-1033.
66. Roberts, S. H., & Bailey, J. E. (2011). Incentives and barriers to lifestyle interventions for people with severe mental illness: A narrative synthesis of quantitative, qualitative and mixed methods studies. Journal of Advanced Nursing, 67(4), 690-708.
67. Rognmo, O., Moholdt, T., Bakken, H., Hole, T., Molstad, P., Myhr, N. E., Wisloff, U. (2012). Cardiovascular risk of high-versus moderate-intensity aerobic exercise in coronary heart disease patients. Circulation, 126(12), 1436-1440.
68. Sassen, B., Cornelissen, V. A., Kiers, H., Wittink, H., Kok, G., & Vanhees, L. (2009). Physical fitness matters more than physical activity in controlling cardiovascular disease risk factors. European Journal of Cardiovascular Prevention & Rehabilitation, 16(6), 677-683.
69. Scheewe, T. W., Takken, T., Kahn, R. S., Cahn, W., & Backx, F. J. (2012). Effects of exercise therapy on cardiorespiratory fitness in patients with schizophrenia. Medicine and Science in Sports Exercise, 44(10), 1834-1842.
70. Sharpe, J. K., Stedman, T. J., Byrne, N. M., Wishart, C., & Hills, A. P. (2006). Energy expenditure and physical activity in clozapine use: Implications for weight management. Australian New Zealand Journal of Psychiatry, 40(9), 810-814.
71. Siren, R., Eriksson, J. G., & Vanhanen, H. (2012). Waist circumference a good indicator of future risk for type 2 diabetes and cardiovascular disease. BMC Public Health, 12, 631.
72. Skrinar, G. S., Huxley, N. A., Hutchinson, D. S., Menninger, E., & Glew, P. (2005). The role of a fitness intervention on people with serious psychiatric disabilities. Psychiatric Rehabilitation Journal, 29(2), 122-127.
73. Stahl, S. M., & Stahl, S. M. (2008). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (3rd ed., fully rev. and expand ed.). Cambridge: Cambridge University Press.
74. Stip, E., Lungu, O. V., Anselmo, K., Letourneau, G., Mendrek, A., Stip, B., Bentaleb, L. A. (2012). Neural changes associated with appetite information processing in schizophrenic patients after 16 weeks of olanzapine treatment. Translational Psychiatry, 2(6), e128.
75. Strassnig, M., Brar, J. S., & Ganguli, R. (2011). Low cardiorespiratory fitness and physical functional capacity in obese patients with schizophrenia. Schizophrenia Research, 126(1-3), 103-109.
76. Takahashi, H., Sassa, T., Shibuya, T., Kato, M., Koeda, M., Murai, T., Okubo, Y. (2012). Effects of sports participation on psychiatric symptoms and brain activations during sports observation in schizophrenia. Translational Psychiatry, 2, e96.
77. Tjonna, A. E., Lee, S. J., Rognmo, O., Stolen, T. O., Bye, A., Haram, P. M., Wisloff, U. (2008). Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: A pilot study. Circulation, 118(4), 346-354.
78. Tjonna, A. E., Stolen, T. O., Bye, A., Volden, M., Slordahl, S. A., Odegard, R., Wisloff, U. (2009). Aerobic interval training reduces cardiovascular risk factors more than a multitreatment approach in overweight adolescents. Clinical Science (Lond), 116(4), 317-326.
79. Trapp, E. G., Chisholm, D. J., Freund, J., & Boutcher, S. H. (2008). The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women. International Journal of Obesity (Lond), 32(4), 684-691.
80. Vancampfort, D., Knapen, J., Probst, M., van Winkel, R., Deckx, S., Maurissen, K., De Hert, M. (2010). Considering a frame of reference for physical activity research related to the cardiometabolic risk profile in schizophrenia. Psychiatry Research, 177(3), 271-279.
81. Vancampfort, D., Probst, M., Helvik Skjaerven, L., Catalan-Matamoros, D., Lundvik-Gyllensten, A., Gomez-Conesa, A., De Hert, M. (2012). Systematic review of the benefits of physical therapy within a multidisciplinary care approach for people with schizophrenia. Physical Therapy, 92(1), 11-23.
82. Werneke, U., Taylor, D., Sanders, T. A., & Wessely, S. (2003). Behavioural management of antipsychotic-induced weight gain: A review. Acta Psychiatrica Scandinavica, 108(4), 252-259.
83. Weston, K. S., Wisloff, U., & Coombes, J. S. (2014). High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: A systematic review and meta-analysis. British Journal of Sports Medicine, 48(16), 1227-1234.
84. Willis, L. H., Slentz, C. A., Bateman, L. A., Shields, A. T., Piner, L. W., Bales, C. W., Kraus, W. E. (2012). Effects of aerobic and/or resistance training on body mass and fat mass in overweight or obese adults. Journal of Applied Physiology, 113(12), 1831-1837.
85. Wisloff, U., Ellingsen, O., & Kemi, O. J. (2009). High-intensity interval training to maximize cardiac benefits of exercise training?. Exercise and Sport Science Reviews, 37(3), 139-146.
86. Wu, M. K., Wang, C. K., Bai, Y. M., Huang, C. Y., & Lee, S. D. (2007). Outcomes of obese, clozapine-treated inpatients with schizophrenia placed on a six-month diet and physical activity program. Psychiatric Services, 58(4), 544-550.
87. Yusuf, S., Hawken, S., Ounpuu, S., Dans, T., Avezum, A., Lanas, F., Investigators, I. S. (2004). Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet, 364(9438), 937-952.