-
1
-
-
84896455574
-
New antituberculosis drugs, regimens, and adjunct therapies: Needs, advances, and future prospects
-
Zumla, A.I.et al. New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects. Lancet Infect. Dis. 14, 327-340 (2014
-
(2014)
Lancet Infect. Dis
, vol.14
, pp. 327-340
-
-
Zumla, A.I.1
-
2
-
-
84906997561
-
Sar analysis of new anti-tb drugs currently in pre-clinical and clinical development
-
Poce, G., Cocozza, M., Consalvi, S. & Biava, M. SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development. Eur. J. Med. Chem. 86, 335-351 (2014
-
(2014)
Eur. J. Med. Chem
, vol.86
, pp. 335-351
-
-
Poce, G.1
Cocozza, M.2
Consalvi, S.3
Biava, M.4
-
3
-
-
77956930778
-
Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism
-
Kim, M. J, et al. Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism. EMBO Mol. Med. 2, 258-274 (2010
-
(2010)
EMBO Mol. Med
, vol.2
, pp. 258-274
-
-
Kim, M.J.1
-
4
-
-
0029976980
-
An in vitro model for sequential study of shiftdown of mycobacterium tuberculosis through two stages of nonreplicating persistence
-
Wayne, L. G. & Hayes, L. G. An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect. Immun. 64, 2062-2069 (1996
-
(1996)
Infect. Immun
, vol.64
, pp. 2062-2069
-
-
Wayne, L.G.1
Hayes, L.G.2
-
5
-
-
84874064350
-
Activities of drug combinations against mycobacterium tuberculosis grown in aerobic and hypoxic acidic conditions
-
Piccaro, G., Giannoni, F., Filippini, P., Mustazzolu, A. & Fattorini, L. Activities of drug combinations against Mycobacterium tuberculosis grown in aerobic and hypoxic acidic conditions. Antimicrob. Agents Chemother. 57, 1428-1433 (2013
-
(2013)
Antimicrob. Agents Chemother
, vol.57
, pp. 1428-1433
-
-
Piccaro, G.1
Giannoni, F.2
Filippini, P.3
Mustazzolu, A.4
Fattorini, L.5
-
6
-
-
84874297088
-
Improved BM212 mmpl3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection
-
Poce, G, et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 8, e56980 (2013
-
(2013)
PLoS One
, vol.8
, pp. e56980
-
-
Poce, G.1
-
7
-
-
38649085328
-
In vitro-selected linezolidresistant mycobacterium tuberculosis mutants
-
Hillemann, D., Rüsch-Gerdes, S. & Richter, E. In vitro-selected linezolidresistant Mycobacterium tuberculosis mutants. Antimicrob. Agents Chemother. 52, 800-801 (2008
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, pp. 800-801
-
-
Hillemann, D.1
Rüsch-Gerdes, S.2
Richter, E.3
-
8
-
-
47349123717
-
Effect of meropenem against multidrug-resistant Mycobacterium tuberculosis
-
Coban, A. Y., Bilgin, K., Tasdelen Fisgin, N., Uzun, M. & Durupinar, B. Effect of meropenem against multidrug-resistant Mycobacterium tuberculosis. J. Chemother. 20, 395-396 (2008
-
(2008)
J. Chemother
, vol.20
, pp. 395-396
-
-
Coban, A.Y.1
Bilgin, K.2
Tasdelen Fisgin, N.3
Uzun, M.4
Durupinar, B.5
-
9
-
-
79952466815
-
Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery
-
Ekins, S., Freundlich, J. S., Choi, I., Sarker, M. & Talcott, C. Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery. Trends Microbiol. 19, 65-74 (2011
-
(2011)
Trends Microbiol
, vol.19
, pp. 65-74
-
-
Ekins, S.1
Freundlich, J.S.2
Choi, I.3
Sarker, M.4
Talcott, C.5
-
10
-
-
84887406804
-
Why are membrane targets discovered by phenotypic screens and genome sequencing in Mycobacterium tuberculosis?
-
Goldman, R. C. Why are membrane targets discovered by phenotypic screens and genome sequencing in Mycobacterium tuberculosis?. Tuberculosis. 93, 569-588 (2013
-
(2013)
Tuberculosis
, vol.93
, pp. 569-588
-
-
Goldman, R.C.1
-
11
-
-
84904208365
-
Predicting natural product value, an exploration of anti-tb drug space
-
Dashti, Y., Grkovic, T. & Quinn, R. J. Predicting natural product value, an exploration of anti-TB drug space. Nat. Prod. Rep. 31, 990-998 (2014
-
(2014)
Nat. Prod. Rep
, vol.31
, pp. 990-998
-
-
Dashti, Y.1
Grkovic, T.2
Quinn, R.J.3
-
12
-
-
84896716778
-
Towards a new combination therapy for tuberculosis with next generation benzothiazinones
-
Makarov, V, et al. Towards a new combination therapy for tuberculosis with next generation benzothiazinones. EMBO Mol. Med. 6, 372-383 (2014
-
(2014)
EMBO Mol. Med
, vol.6
, pp. 372-383
-
-
Makarov, V.1
-
13
-
-
84948651641
-
-
ed. Mandic E. International Association of Physical Chemists (IAPC) Publishing, Zagreb, Croatia
-
Takacs-Novak, K. in Physico-Chemical Methods in Drug Discovery and Development (ed. Mandic E.) 2-52 International Association of Physical Chemists (IAPC) Publishing, Zagreb, Croatia, (2012
-
(2012)
Physico-Chemical Methods in Drug Discovery and Development
, pp. 2-52
-
-
Takacs-Novak, K.1
-
14
-
-
84908126151
-
Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis
-
Gillespie, S. H, et al. Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis. N. Engl. J. Med. 371, 1577-1587 (2014
-
(2014)
N. Engl. J. Med
, vol.371
, pp. 1577-1587
-
-
Gillespie, S.H.1
-
15
-
-
84908147456
-
A four-month gatifloxacin-containing regimen for treating tuberculosis
-
Merle, C. S, et al A four-month gatifloxacin-containing regimen for treating tuberculosis. N. Engl. J. Med. 371, 1588-1598 (2014
-
(2014)
N. Engl. J. Med
, vol.371
, pp. 1588-1598
-
-
Merle, C.S.1
-
16
-
-
84908139920
-
High-dose rifapentine with moxifloxacin for pulmonary tuberculosis
-
Jindani, A, et al. High-dose rifapentine with moxifloxacin for pulmonary tuberculosis. N. Engl. J. Med. 371, 1599-1608 (2014
-
(2014)
N. Engl. J. Med
, vol.371
, pp. 1599-1608
-
-
Jindani, A.1
-
17
-
-
84914701171
-
-
World Health Organization Chapter 9: Research and development. WHO/HTM/TB/2014. 08
-
World Health Organization. Global Tuberculosis Report 2014. Chapter 9: Research and development. WHO/HTM/TB/2014.08.
-
(2014)
Global Tuberculosis Report
-
-
-
18
-
-
84861137329
-
Sterilizing activities of novel combinations lacking first- and secondline drugs in a murine model of tuberculosis
-
Williams, K, et al. Sterilizing activities of novel combinations lacking first- and secondline drugs in a murine model of tuberculosis. Antimicrob. Agents Chemother. 56, 3114-3120 (2012
-
(2012)
Antimicrob. Agents Chemother
, vol.56
, pp. 3114-3120
-
-
Williams, K.1
-
19
-
-
84920127117
-
Contribution of the nitroimidazoles pa-824 and tba-354 to the activity of novel regimens in murine models of tuberculosis
-
Tasneen, R, et al. Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis. Antimicrob. Agents Chemother. 59, 129-135 (2015
-
(2015)
Antimicrob. Agents Chemother
, vol.59
, pp. 129-135
-
-
Tasneen, R.1
-
20
-
-
84875205011
-
Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating mycobacterium tuberculosis
-
Sarathy, J., Dartois, V., Dick, T. & Gengenbacher, M. Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 57, 1648-1653 (2013
-
(2013)
Antimicrob. Agents Chemother
, vol.57
, pp. 1648-1653
-
-
Sarathy, J.1
Dartois, V.2
Dick, T.3
Gengenbacher, M.4
-
21
-
-
84895541126
-
Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix
-
Bacon, J, et al. Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix. PLoS One. 9, e87329 (2014
-
(2014)
PLoS One
, vol.9
, pp. e87329
-
-
Bacon, J.1
-
22
-
-
84918534582
-
An acyl-coa synthetase in Mycobacterium tuberculosis involved in triacylglycerol accumulation during dormancy
-
Daniel, J., Sirakova, T. & Kolattukudy, P. An acyl-CoA synthetase in Mycobacterium tuberculosis involved in triacylglycerol accumulation during dormancy. PLoS One. 9, e114877 (2014
-
(2014)
PLoS One
, vol.9
, pp. e114877
-
-
Daniel, J.1
Sirakova, T.2
Kolattukudy, P.3
-
23
-
-
84894068321
-
The path of anti-tuberculosis drugs: From blood to lesions to mycobacterial cells
-
Dartois, V. The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells. Nat. Rev. Microbiol. 12, 159-167 (2014
-
(2014)
Nat. Rev. Microbiol
, vol.12
, pp. 159-167
-
-
Dartois, V.1
-
24
-
-
84923172431
-
Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses
-
Lenaerts, A., Barry, C. E. 3rd & Dartois, V. Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses. Immunol. Rev. 264, 288-307 (2015
-
(2015)
Immunol. Rev
, vol.264
, pp. 288-307
-
-
Lenaerts, A.1
Barry, C.E.2
Dartois, V.3
-
25
-
-
84928178295
-
Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-tb agents
-
Lakshminarayana, S. B, et al. Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents. J. Antimicrob. Chemother. 70, 857-867 (2015
-
(2015)
J. Antimicrob. Chemother
, vol.70
, pp. 857-867
-
-
Lakshminarayana, S.B.1
|