Non-replicating Mycobacterium tuberculosis elicits a reduced infectivity profile with corresponding modifications to the cell wall and extracellular matrix

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Bacon, Joanna ^a   Alderwick, Luke J ^b   Allnutt, Jon A ^a   Gabasova, Evelina ^c   Watson, Robert ^a   Hatch, Kim A ^a   Clark, Simon O ^a   Jeeves, Rose E ^a   Marriott, Alice ^a   Rayner, Emma ^a   Tolley, Howard ^a   Pearson, Geoff ^a   Hall, Graham ^a   Besra, Gurdyal S ^b   Wernisch, Lorenz ^c   Williams, Ann ^a   Marsh, Philip D ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL VIRULENCE; BIOFILM; CARBOHYDRATE ANALYSIS; CELL DIVISION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENERGY METABOLISM; EXTRACELLULAR MATRIX; FATTY ACID METABOLISM; GENE EXPRESSION PROFILING; HYDROLYSIS; IMMUNOGENICITY; LIPID DEGRADATION; MICROARRAY ANALYSIS; MORPHOLOGY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; PROBABILITY; PROTEIN DEPLETION; THIN LAYER CHROMATOGRAPHY; TRANSCRIPTOMICS; ADAPTATION; ANIMAL; BACTERIAL LOAD; CELL WALL; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; GUINEA PIG; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MOUSE; MULTIGENE FAMILY; MYCOBACTERIOSIS; PATHOGENICITY; PATHOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; ULTRASTRUCTURE; UPREGULATION;

CARBOHYDRATE; CARBON; POLYSORBATE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BACTERIAL LOAD; CARBOHYDRATES; CARBON; CELL WALL; CHROMATOGRAPHY, THIN LAYER; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GUINEA PIGS; MICE; MOLECULAR SEQUENCE ANNOTATION; MULTIGENE FAMILY; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM TUBERCULOSIS; POLYSORBATES; UP-REGULATION;

EID: 84895541126     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087329     Document Type: Article

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