메뉴 건너뛰기




Volumn 29, Issue 2, 2015, Pages 770-778

Activation of Nrf2/HO-1signaling pathway involves the anti-inflammatory activity of magnolol in Porphyromonas gingivalis lipopolysaccharide-stimulated mouse RAW 264.7 macrophages

Author keywords

Heme oxygenase 1; Inflammation; Lipopolysaccharide; Magnolol; Porphyromonas gingivalis

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYCLOOXYGENASE 2; CYTOKINE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MAGNOLOL; NITRITE; PROSTAGLANDIN E2; PROTOPORPHYRIN TIN; TRANSCRIPTION FACTOR NRF2; BIPHENYL DERIVATIVE; LIGNAN; LIPOPOLYSACCHARIDE; METALLOPORPHYRIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NFE2L2 PROTEIN, MOUSE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTOPORPHYRIN; REACTIVE OXYGEN METABOLITE;

EID: 84948581105     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.08.042     Document Type: Article
Times cited : (45)

References (32)
  • 1
    • 72249085837 scopus 로고    scopus 로고
    • Host-parasite interactions in periodontitis: Subgingival infection and host sensing
    • A. Amano Host-parasite interactions in periodontitis: subgingival infection and host sensing Periodontol. 52 2010 7 11
    • (2010) Periodontol. , vol.52 , pp. 7-11
    • Amano, A.1
  • 2
    • 0141448875 scopus 로고    scopus 로고
    • Receptor activator NF kappaB ligand (RANKL) and osteoprotegerin (OPG) protein expression in periodontitis
    • T. Crotti, M.D. Smith, R. Hirsch, S. Soukoulis, H. Weedon, and M. Capone Receptor activator NF kappaB ligand (RANKL) and osteoprotegerin (OPG) protein expression in periodontitis J. Periodontal Res. 38 2003 380 387
    • (2003) J. Periodontal Res. , vol.38 , pp. 380-387
    • Crotti, T.1    Smith, M.D.2    Hirsch, R.3    Soukoulis, S.4    Weedon, H.5    Capone, M.6
  • 4
    • 77953192729 scopus 로고    scopus 로고
    • Mechanisms and control of pathologic bone loss in periodontitis
    • P.M. Bartold, M.D. Cantley, and D.R. Haynes Mechanisms and control of pathologic bone loss in periodontitis Periodontol. 53 2010 55 69
    • (2010) Periodontol. , vol.53 , pp. 55-69
    • Bartold, P.M.1    Cantley, M.D.2    Haynes, D.R.3
  • 5
    • 77953616099 scopus 로고    scopus 로고
    • Periodontitis: A polymicrobial disruption of host homeostasis
    • R.P. Darveau Periodontitis: a polymicrobial disruption of host homeostasis Nat. Rev. Microbiol. 8 2010 481 490
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 481-490
    • Darveau, R.P.1
  • 7
    • 78049442406 scopus 로고    scopus 로고
    • Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
    • A. Paine, B. Eiz Vesper, R. Blasczyk, and S. Immenschuh Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential Biochem. Pharmacol. 80 2010 1895 1903
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 1895-1903
    • Paine, A.1    Eiz Vesper, B.2    Blasczyk, R.3    Immenschuh, S.4
  • 8
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • N.G. Abraham, and A. Kappas Pharmacological and clinical aspects of heme oxygenase Pharmacol. Rev. 60 2008 79 127
    • (2008) Pharmacol. Rev. , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 9
    • 0030886054 scopus 로고    scopus 로고
    • Reduced stress defense in heme oxygenase 1-deficient cells
    • K.D. Poss, and S. Tonegawa Reduced stress defense in heme oxygenase 1-deficient cells Proc. Natl. Acad. Sci. U. S. A. 94 1997 10925 10930
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 10925-10930
    • Poss, K.D.1    Tonegawa, S.2
  • 10
    • 84886777392 scopus 로고    scopus 로고
    • Inhibitory effects of tert-butylhydroquinone on osteoclast differentiation via up-regulation of heme oxygenase-1 and down-regulation of HMGB1 release and NFATc1 expression
    • Y. Yamaguchi, E. Sakai, H. Sakamoto, R. Fumimoto, Y. Fukuma, K. Nishishita, K. Okamoto, and T. Tsukuba Inhibitory effects of tert-butylhydroquinone on osteoclast differentiation via up-regulation of heme oxygenase-1 and down-regulation of HMGB1 release and NFATc1 expression J. Appl. Toxicol. 34 2014 49 56
    • (2014) J. Appl. Toxicol. , vol.34 , pp. 49-56
    • Yamaguchi, Y.1    Sakai, E.2    Sakamoto, H.3    Fumimoto, R.4    Fukuma, Y.5    Nishishita, K.6    Okamoto, K.7    Tsukuba, T.8
  • 11
    • 84874111758 scopus 로고    scopus 로고
    • The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation
    • H.K. Bryan, A. Olayanju, C.E. Goldring, and B.K. Park The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation Biochem. Pharmacol. 85 2013 705 717
    • (2013) Biochem. Pharmacol. , vol.85 , pp. 705-717
    • Bryan, H.K.1    Olayanju, A.2    Goldring, C.E.3    Park, B.K.4
  • 12
    • 79960698211 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 via PI3K/Akt and Nrf-2 signaling pathways mediates the anti-inflammatory activity of schisandrin in Porphyromonas gingivalis LPS-stimulated macrophages
    • S.Y. Park, J. Park da, Y.H. Kim, Y. Kim, S.G. Kim, and K.J. Shon Upregulation of heme oxygenase-1 via PI3K/Akt and Nrf-2 signaling pathways mediates the anti-inflammatory activity of schisandrin in Porphyromonas gingivalis LPS-stimulated macrophages Immunol. Lett. 139 2011 93 101
    • (2011) Immunol. Lett. , vol.139 , pp. 93-101
    • Park, S.Y.1    Parkda, J.2    Kim, Y.H.3    Kim, Y.4    Kim, S.G.5    Shon, K.J.6
  • 13
    • 1942455887 scopus 로고    scopus 로고
    • Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles
    • K. Itoh, K.I. Tong, and M. Yamamoto Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles Free Radic. Biol. Med. 36 2004 1208 1213
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 1208-1213
    • Itoh, K.1    Tong, K.I.2    Yamamoto, M.3
  • 15
    • 84864942152 scopus 로고    scopus 로고
    • The antiplatelet activity of magnolol is mediated by PPAR-beta/gamma
    • C.Y. Shih, and T.C. Chou The antiplatelet activity of magnolol is mediated by PPAR-beta/gamma Biochem. Pharmacol. 84 2012 793 803
    • (2012) Biochem. Pharmacol. , vol.84 , pp. 793-803
    • Shih, C.Y.1    Chou, T.C.2
  • 18
    • 84871290824 scopus 로고    scopus 로고
    • Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-kappaB and MAPKs signaling pathways
    • Y. Fu, B. Liu, N. Zhang, Z. Liu, D. Liang, and F. Li Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-kappaB and MAPKs signaling pathways J. Ethnopharmacol. 145 2013 193 199
    • (2013) J. Ethnopharmacol. , vol.145 , pp. 193-199
    • Fu, Y.1    Liu, B.2    Zhang, N.3    Liu, Z.4    Liang, D.5    Li, F.6
  • 19
    • 84876550088 scopus 로고    scopus 로고
    • Magnolol ameliorates ligature-induced periodontitis in rats and osteoclastogenesis: In vivo and in vitro study
    • S.H. Lu, R.Y. Huang, and T.C. Chou Magnolol ameliorates ligature-induced periodontitis in rats and osteoclastogenesis: in vivo and in vitro study Evid. Based Complement. Alternat. Med. 634095 2013
    • (2013) Evid. Based Complement. Alternat. Med. , vol.634
    • Lu, S.H.1    Huang, R.Y.2    Chou, T.C.3
  • 20
    • 80053343616 scopus 로고    scopus 로고
    • Simvastatin inhibits pro-inflammatory mediators through induction of heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW 264.7 macrophages
    • P.O. Leung, S.H. Wang, S.H. Lu, W.H. Chou, C.Y. Shiau, and T.C. Chou Simvastatin inhibits pro-inflammatory mediators through induction of heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW 264.7 macrophages Toxicol. Lett. 207 2011 159 166
    • (2011) Toxicol. Lett. , vol.207 , pp. 159-166
    • Leung, P.O.1    Wang, S.H.2    Lu, S.H.3    Chou, W.H.4    Shiau, C.Y.5    Chou, T.C.6
  • 21
    • 77749237377 scopus 로고    scopus 로고
    • 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway
    • Y. Furukawa, T. Urano, M. Minamimura, M. Nakajima, S. Okuyama, and S. Furukawa 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway Biomed. Res. 31 2010 45 52
    • (2010) Biomed. Res. , vol.31 , pp. 45-52
    • Furukawa, Y.1    Urano, T.2    Minamimura, M.3    Nakajima, M.4    Okuyama, S.5    Furukawa, S.6
  • 22
    • 33644501791 scopus 로고    scopus 로고
    • Activation of the Nrf2-ARE signaling pathway: A promising strategy in cancer prevention
    • A. Giudice, and M. Montella Activation of the Nrf2-ARE signaling pathway: a promising strategy in cancer prevention BioEssays 28 2006 169 181
    • (2006) BioEssays , vol.28 , pp. 169-181
    • Giudice, A.1    Montella, M.2
  • 23
    • 84898785937 scopus 로고    scopus 로고
    • Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics
    • A.L. Levonen, B.G. Hill, E. Kansanen, J. Zhang, and V.M. Darley Usmar Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics Free Radic. Biol. Med. 71 2014 196 207
    • (2014) Free Radic. Biol. Med. , vol.71 , pp. 196-207
    • Levonen, A.L.1    Hill, B.G.2    Kansanen, E.3    Zhang, J.4    Darley Usmar, V.M.5
  • 24
    • 3142570440 scopus 로고    scopus 로고
    • The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
    • T. Nguyen, C.S. Yang, and C.B. Pickett The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress Free Radic. Biol. Med. 37 2004 433 441
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 433-441
    • Nguyen, T.1    Yang, C.S.2    Pickett, C.B.3
  • 25
    • 33646050056 scopus 로고    scopus 로고
    • Heme oxygenase-1 contributes to the cytoprotection of alpha-lipoic acid via activation of p44/42 mitogen-activated protein kinase in vascular smooth muscle cells
    • P.Y. Cheng, Y.M. Lee, N.L. Shih, Y.C. Chen, and M.H. Yen Heme oxygenase-1 contributes to the cytoprotection of alpha-lipoic acid via activation of p44/42 mitogen-activated protein kinase in vascular smooth muscle cells Free Radic. Biol. Med. 40 2006 1313 1322
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 1313-1322
    • Cheng, P.Y.1    Lee, Y.M.2    Shih, N.L.3    Chen, Y.C.4    Yen, M.H.5
  • 26
    • 84866736492 scopus 로고    scopus 로고
    • Inhibitory effects of Ginkgo biloba extract on inflammatory mediator production by Porphyromonas gingivalis lipopolysaccharide in murine macrophages via Nrf-2 mediated heme oxygenase-1 signaling pathways
    • E.Y. Ryu, A.J. Park, S.Y. Park, S.H. Park, H.W. Eom, Y.H. Kim, G. Park, and S.J. Lee Inhibitory effects of Ginkgo biloba extract on inflammatory mediator production by Porphyromonas gingivalis lipopolysaccharide in murine macrophages via Nrf-2 mediated heme oxygenase-1 signaling pathways Inflammation 35 2012 1477 1486
    • (2012) Inflammation , vol.35 , pp. 1477-1486
    • Ryu, E.Y.1    Park, A.J.2    Park, S.Y.3    Park, S.H.4    Eom, H.W.5    Kim, Y.H.6    Park, G.7    Lee, S.J.8
  • 27
    • 0034746919 scopus 로고    scopus 로고
    • NF-kappaB: A key role in inflammatory diseases
    • P.P. Tak, and G.S. Firestein NF-kappaB: a key role in inflammatory diseases J. Clin. Invest. 107 2001 7 11
    • (2001) J. Clin. Invest. , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 28
    • 57449111441 scopus 로고    scopus 로고
    • Regulatory potential for concerted modulation of Nrf2- and NF-κB-mediated gene expression in inflammation and carcinogenesis
    • S. Nair, S.T. Doh, J.Y. Chan, A.N. Kong, and L. Cai Regulatory potential for concerted modulation of Nrf2- and NF-κB-mediated gene expression in inflammation and carcinogenesis Br. J. Cancer 99 2008 2070 2082
    • (2008) Br. J. Cancer , vol.99 , pp. 2070-2082
    • Nair, S.1    Doh, S.T.2    Chan, J.Y.3    Kong, A.N.4    Cai, L.5
  • 29
    • 59549099432 scopus 로고    scopus 로고
    • Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury
    • W. Jin, H. Wang, W. Yan, L. Xu, X. Wang, X. Zhao, X. Yang, G. Chen, and Y. Ji Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury Mediat. Inflamm. 725174 2008
    • (2008) Mediat. Inflamm. , vol.725
    • Jin, W.1    Wang, H.2    Yan, W.3    Xu, L.4    Wang, X.5    Zhao, X.6    Yang, X.7    Chen, G.8    Ji, Y.9
  • 30
    • 77955653742 scopus 로고    scopus 로고
    • Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation
    • J.E. Kim, D.J. You, C. Lee, C. Ahn, J.Y. Seong, and J.I. Hwang Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation Cell. Signal. 22 2010 1645 1654
    • (2010) Cell. Signal. , vol.22 , pp. 1645-1654
    • Kim, J.E.1    You, D.J.2    Lee, C.3    Ahn, C.4    Seong, J.Y.5    Hwang, J.I.6
  • 32
    • 79251605391 scopus 로고    scopus 로고
    • Heme oxygenase-1/carbon monoxide: Novel therapeutic strategies in critical care medicine
    • S.W. Ryter, and A.M. Choi Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine Curr. Drug Targets 11 2010 1485 1494
    • (2010) Curr. Drug Targets , vol.11 , pp. 1485-1494
    • Ryter, S.W.1    Choi, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.