메뉴 건너뛰기




Volumn 9, Issue 11, 2015, Pages 11064-11074

A Near-Infrared Triggered Nanophotosensitizer Inducing Domino Effect on Mitochondrial Reactive Oxygen Species Burst for Cancer Therapy

Author keywords

cancer therapy; domino effect; nanophotosensitizer; near infrared; reactive oxygen species

Indexed keywords

CELL DEATH; DISEASES; LIGHT; MITOCHONDRIA; ONCOLOGY; OXYGEN; PHOTODYNAMIC THERAPY; PHOTOSENSITIZERS;

EID: 84948463020     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b04501     Document Type: Article
Times cited : (292)

References (57)
  • 1
    • 55749099142 scopus 로고    scopus 로고
    • Nanoparticles in photodynamic therapy: An emerging paradigm
    • Chatterjee, D. K.; Fong, L. S.; Zhang, Y. Nanoparticles in photodynamic therapy: an emerging paradigm Adv. Drug Delivery Rev. 2008, 60, 1627-1637 10.1016/j.addr.2008.08.003
    • (2008) Adv. Drug Delivery Rev. , vol.60 , pp. 1627-1637
    • Chatterjee, D.K.1    Fong, L.S.2    Zhang, Y.3
  • 2
    • 77952496220 scopus 로고    scopus 로고
    • Activatable Photosensitizers for Imaging and Therapy
    • Lovell, J. F.; Liu, T. W. B.; Chen, J.; Zheng, G. Activatable Photosensitizers for Imaging and Therapy Chem. Rev. 2010, 110, 2839-2857 10.1021/cr900236h
    • (2010) Chem. Rev. , vol.110 , pp. 2839-2857
    • Lovell, J.F.1    Liu, T.W.B.2    Chen, J.3    Zheng, G.4
  • 3
    • 84910120194 scopus 로고    scopus 로고
    • Functional Nanomaterials for Phototherapies of Cancer
    • Cheng, L.; Wang, C.; Feng, L.; Yang, K.; Liu, Z. Functional Nanomaterials for Phototherapies of Cancer Chem. Rev. 2014, 114, 10869-10939 10.1021/cr400532z
    • (2014) Chem. Rev. , vol.114 , pp. 10869-10939
    • Cheng, L.1    Wang, C.2    Feng, L.3    Yang, K.4    Liu, Z.5
  • 4
    • 84907341406 scopus 로고    scopus 로고
    • A Graphene Quantum Dot Photodynamic Therapy Agent with High Singlet Oxygen Generation
    • Ge, J.; Lan, M.; Zhou, B.; Liu, W.; Guo, L.; Wang, H.; Jia, Q.; Niu, G.; Huang, X.; Zhou, H. et al. A Graphene Quantum Dot Photodynamic Therapy Agent with High Singlet Oxygen Generation Nat. Commun. 2014, 5, 4596-4603 10.1038/ncomms5596
    • (2014) Nat. Commun. , vol.5 , pp. 4596-4603
    • Ge, J.1    Lan, M.2    Zhou, B.3    Liu, W.4    Guo, L.5    Wang, H.6    Jia, Q.7    Niu, G.8    Huang, X.9    Zhou, H.10
  • 5
    • 77954900191 scopus 로고    scopus 로고
    • Targeted Therapy of Cancer Using Photodynamic Therapy in Combination with Multi-faceted Anti-Tumor Modalities
    • Olivo, M.; Bhuvaneswari, R.; Lucky, S. S.; Dendukuri, N.; Thong, P. S. Targeted Therapy of Cancer Using Photodynamic Therapy in Combination with Multi-faceted Anti-Tumor Modalities Pharmaceuticals 2010, 3, 1507-1529 10.3390/ph3051507
    • (2010) Pharmaceuticals , vol.3 , pp. 1507-1529
    • Olivo, M.1    Bhuvaneswari, R.2    Lucky, S.S.3    Dendukuri, N.4    Thong, P.S.5
  • 7
    • 33745537921 scopus 로고    scopus 로고
    • Photodynamic therapy and anti-tumour immunity
    • Castano, A. P.; Mroz, P.; Hamblin, M. R. Photodynamic therapy and anti-tumour immunity Nat. Rev. Cancer 2006, 6, 535-545 10.1038/nrc1894
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 535-545
    • Castano, A.P.1    Mroz, P.2    Hamblin, M.R.3
  • 8
    • 58549104170 scopus 로고    scopus 로고
    • Photodynamic Therapy for Prostate Cancer-A Review of Current Status and Future Promise
    • Moore, C. M.; Pendse, D.; Emberton, M. Photodynamic Therapy for Prostate Cancer-A Review of Current Status and Future Promise Nat. Clin. Pract. Urol. 2009, 6, 18-30 10.1038/ncpuro1274
    • (2009) Nat. Clin. Pract. Urol. , vol.6 , pp. 18-30
    • Moore, C.M.1    Pendse, D.2    Emberton, M.3
  • 9
    • 84865140748 scopus 로고    scopus 로고
    • Chemical Molecule-Induced Light-Activated System for Anticancer and Antifungal Activities
    • Yuan, H.; Chong, H.; Wang, B.; Zhu, C.; Liu, L.; Yang, Q.; Lv, F.; Wang, S. Chemical Molecule-Induced Light-Activated System for Anticancer and Antifungal Activities J. Am. Chem. Soc. 2012, 134, 13184-13187 10.1021/ja304986t
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 13184-13187
    • Yuan, H.1    Chong, H.2    Wang, B.3    Zhu, C.4    Liu, L.5    Yang, Q.6    Lv, F.7    Wang, S.8
  • 10
    • 85047688673 scopus 로고    scopus 로고
    • Direct Near-infrared Luminescence Detection of Singlet Oxygen Generated by Photodynamic Therapy in Cells in Vitro and Tissues in Vivo
    • Niedre, M.; Patterson, M. S.; Wilson, B. C. Direct Near-infrared Luminescence Detection of Singlet Oxygen Generated by Photodynamic Therapy in Cells In Vitro and Tissues In Vivo Photochem. Photobiol. 2002, 75, 382-391 10.1562/0031-8655(2002)0750382DNILDO2.0.CO2
    • (2002) Photochem. Photobiol. , vol.75 , pp. 382-391
    • Niedre, M.1    Patterson, M.S.2    Wilson, B.C.3
  • 12
    • 78650356299 scopus 로고    scopus 로고
    • The Role of Porphyrin Chemistry in Tumor Imaging and Photodynamic Therapy
    • Ethirajan, M.; Chen, Y.; Joshi, P.; Pandey, R. K. The Role of Porphyrin Chemistry in Tumor Imaging and Photodynamic Therapy Chem. Soc. Rev. 2011, 40, 340-362 10.1039/B915149B
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 340-362
    • Ethirajan, M.1    Chen, Y.2    Joshi, P.3    Pandey, R.K.4
  • 14
    • 34948875233 scopus 로고    scopus 로고
    • Measuring the Lifetime of Singlet Oxygen in A Single Cell: Addressing the Issue of Cell Viability
    • Hatz, S.; Lambert, J. D. C.; Ogilby, P. R. Measuring the Lifetime of Singlet Oxygen in A Single Cell: Addressing the Issue of Cell Viability Photochem. Photobiol. Sci. 2007, 6, 1106-1116 10.1039/b707313e
    • (2007) Photochem. Photobiol. Sci. , vol.6 , pp. 1106-1116
    • Hatz, S.1    Lambert, J.D.C.2    Ogilby, P.R.3
  • 15
    • 84871629685 scopus 로고    scopus 로고
    • Synthesis and in Vitro Biological Evaluation of Lipophilic Cation Conjugated Photosensitizers for Targeting Mitochondria
    • Rajaputra, P.; Nkepang, G.; Watley, R.; You, Y. Synthesis and In Vitro Biological Evaluation of Lipophilic Cation Conjugated Photosensitizers for Targeting Mitochondria Bioorg. Med. Chem. 2013, 21, 379-387 10.1016/j.bmc.2012.11.032
    • (2013) Bioorg. Med. Chem. , vol.21 , pp. 379-387
    • Rajaputra, P.1    Nkepang, G.2    Watley, R.3    You, Y.4
  • 16
    • 84921813517 scopus 로고    scopus 로고
    • Titania Coated Upconversion Nanoparticles for Near-Infrared Light Triggered Photodynamic Therapy
    • Lucky, S. S.; Idris, N. M.; Li, Z.; Huang, K.; Soo, K. C.; Zhang, Y. Titania Coated Upconversion Nanoparticles for Near-Infrared Light Triggered Photodynamic Therapy ACS Nano 2015, 9, 191-205 10.1021/nn503450t
    • (2015) ACS Nano , vol.9 , pp. 191-205
    • Lucky, S.S.1    Idris, N.M.2    Li, Z.3    Huang, K.4    Soo, K.C.5    Zhang, Y.6
  • 17
    • 84925652434 scopus 로고    scopus 로고
    • UV-Emitting Upconversion-Based TiO2 Photosensitizing Nanoplatform: Near-Infrared Light Mediated in Vivo Photodynamic Therapy via Mitochondria-Involved Apoptosis Pathway
    • Hou, Z.; Zhang, Y.; Deng, K.; Chen, Y.; Li, X.; Deng, X.; Cheng, Z.; Lian, H.; Li, C.; Lin, J. UV-Emitting Upconversion-Based TiO2 Photosensitizing Nanoplatform: Near-Infrared Light Mediated in Vivo Photodynamic Therapy via Mitochondria-Involved Apoptosis Pathway ACS Nano 2015, 9, 2584-2599 10.1021/nn506107c
    • (2015) ACS Nano , vol.9 , pp. 2584-2599
    • Hou, Z.1    Zhang, Y.2    Deng, K.3    Chen, Y.4    Li, X.5    Deng, X.6    Cheng, Z.7    Lian, H.8    Li, C.9    Lin, J.10
  • 18
    • 84864691258 scopus 로고    scopus 로고
    • Covalently Assembled NIR Nanoplatform for Simultaneous Fluorescence Imaging and Photodynamic Therapy of Cancer Cells
    • Liu, K.; Liu, X.; Zeng, Q.; Zhang, Y.; Tu, L.; Liu, T.; Kong, X.; Wang, Y.; Cao, F.; Lambrechts, S. A. G. et al. Covalently Assembled NIR Nanoplatform for Simultaneous Fluorescence Imaging and Photodynamic Therapy of Cancer Cells ACS Nano 2012, 6, 4054-4062 10.1021/nn300436b
    • (2012) ACS Nano , vol.6 , pp. 4054-4062
    • Liu, K.1    Liu, X.2    Zeng, Q.3    Zhang, Y.4    Tu, L.5    Liu, T.6    Kong, X.7    Wang, Y.8    Cao, F.9    Lambrechts, S.A.G.10
  • 19
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, Oxidants, and Aging
    • Balaban, R. S.; Nemoto, S.; Finkel, T. Mitochondria, Oxidants, and Aging Cell 2005, 120, 483-495 10.1016/j.cell.2005.02.001
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 21
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial Membrane Permeabilization in Cell Death
    • Kroemer, G.; Galluzzi, L.; Brenner, C. Mitochondrial Membrane Permeabilization in Cell Death Physiol. Rev. 2007, 87, 99-163 10.1152/physrev.00013.2006
    • (2007) Physiol. Rev. , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 22
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial Diseases in Man and Mouse
    • Wallace, D. C. Mitochondrial Diseases in Man and Mouse Science 1999, 283, 1482-1488 10.1126/science.283.5407.1482
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 23
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial Dysfunction and Oxidative Stress in Neurodegenerative Diseases
    • Lin, M. T.; Beal, M. F. Mitochondrial Dysfunction and Oxidative Stress in Neurodegenerative Diseases Nature 2006, 443, 787-795 10.1038/nature05292
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 24
    • 44449147036 scopus 로고    scopus 로고
    • Tumor Cell Metabolism: Cancer's Achilles' Heel
    • Kroemer, G.; Pouyssegur, J. Tumor Cell Metabolism: Cancer's Achilles' Heel Cancer Cell 2008, 13, 472-482 10.1016/j.ccr.2008.05.005
    • (2008) Cancer Cell , vol.13 , pp. 472-482
    • Kroemer, G.1    Pouyssegur, J.2
  • 25
    • 34547578624 scopus 로고    scopus 로고
    • Sequential Opening of Mitochondrial Ion Channels as a Function of Glutathione Redox Thiol Status
    • Aon, M. A.; Cortassa, S.; Maack, C.; O'Rourke, B. Sequential Opening of Mitochondrial Ion Channels as a Function of Glutathione Redox Thiol Status J. Biol. Chem. 2007, 282, 21889-21900 10.1074/jbc.M702841200
    • (2007) J. Biol. Chem. , vol.282 , pp. 21889-21900
    • Aon, M.A.1    Cortassa, S.2    Maack, C.3    O'Rourke, B.4
  • 26
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and Apoptosis
    • Green, D. R.; Reed, J. C. Mitochondria and Apoptosis Science 1998, 281, 1309-1312 10.1126/science.281.5381.1309
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 27
    • 0037621465 scopus 로고    scopus 로고
    • Potentiation of Fas-Mediated Apoptosis by Attenuated Production of Mitochondria-Derived Reactive Oxygen Species
    • Aronis, A.; Melendez, J. A.; Golan, O.; Shilo, S.; Dicter, N.; Tirosh, O. Potentiation of Fas-Mediated Apoptosis by Attenuated Production of Mitochondria-Derived Reactive Oxygen Species Cell Death Differ. 2003, 10, 335-344 10.1038/sj.cdd.4401150
    • (2003) Cell Death Differ. , vol.10 , pp. 335-344
    • Aronis, A.1    Melendez, J.A.2    Golan, O.3    Shilo, S.4    Dicter, N.5    Tirosh, O.6
  • 29
    • 84872852396 scopus 로고    scopus 로고
    • In Vivo Targeted Deep-Tissue Photodynamic Therapy Based on Near-Infrared Light Triggered Upconversion Nanoconstruct
    • Cui, S.; Yin, D.; Chen, Y.; Di, Y.; Chen, H.; Ma, Y.; Achilefu, S.; Gu, Y. In Vivo Targeted Deep-Tissue Photodynamic Therapy Based on Near-Infrared Light Triggered Upconversion Nanoconstruct ACS Nano 2013, 7, 676-688 10.1021/nn304872n
    • (2013) ACS Nano , vol.7 , pp. 676-688
    • Cui, S.1    Yin, D.2    Chen, Y.3    Di, Y.4    Chen, H.5    Ma, Y.6    Achilefu, S.7    Gu, Y.8
  • 30
    • 77649096724 scopus 로고    scopus 로고
    • Simultaneous Phase and Size Control of Upconversion Nanocrystals Through Lanthanide Doping
    • Wang, F.; Han, Y.; Lim, C. S.; Lu, Y.; Wang, J.; Xu, J.; Chen, H.; Zhang, C.; Hong, M.; Liu, X. Simultaneous Phase and Size Control of Upconversion Nanocrystals Through Lanthanide Doping Nature 2010, 463, 1061-1065 10.1038/nature08777
    • (2010) Nature , vol.463 , pp. 1061-1065
    • Wang, F.1    Han, Y.2    Lim, C.S.3    Lu, Y.4    Wang, J.5    Xu, J.6    Chen, H.7    Zhang, C.8    Hong, M.9    Liu, X.10
  • 31
    • 81955164771 scopus 로고    scopus 로고
    • Tuning Upconversion through Energy Migration in Core-Shell Nanoparticles
    • Wang, F.; Deng, R.; Wang, J.; Wang, Q.; Han, Y.; Zhu, H.; Chen, X.; Liu, X. Tuning Upconversion through Energy Migration in Core-Shell Nanoparticles Nat. Mater. 2011, 10, 968-973 10.1038/nmat3149
    • (2011) Nat. Mater. , vol.10 , pp. 968-973
    • Wang, F.1    Deng, R.2    Wang, J.3    Wang, Q.4    Han, Y.5    Zhu, H.6    Chen, X.7    Liu, X.8
  • 33
    • 84924565892 scopus 로고    scopus 로고
    • Lanthanide-Doped Upconversion Nano-Bioprobes: Electronic Structures, Optical Properties, and Biodetection
    • Zheng, W.; Huang, P.; Tu, D.; Ma, E.; Zhu, H.; Chen, X. Lanthanide-Doped Upconversion Nano-Bioprobes: Electronic Structures, Optical Properties, and Biodetection Chem. Soc. Rev. 2015, 44, 1379-1415 10.1039/C4CS00178H
    • (2015) Chem. Soc. Rev. , vol.44 , pp. 1379-1415
    • Zheng, W.1    Huang, P.2    Tu, D.3    Ma, E.4    Zhu, H.5    Chen, X.6
  • 34
    • 84903594941 scopus 로고    scopus 로고
    • Lanthanide-Doped Upconversion Nanoparticles Electrostatically Coupled with Photosensitizers for Near-Infrared-Triggered Photodynamic Therapy
    • Wang, M.; Chen, Z.; Zheng, W.; Zhu, H.; Lu, S.; Ma, E.; Tu, D.; Zhou, S.; Huang, M.; Chen, X. Lanthanide-Doped Upconversion Nanoparticles Electrostatically Coupled with Photosensitizers for Near-Infrared-Triggered Photodynamic Therapy Nanoscale 2014, 6, 8274-8282 10.1039/c4nr01826e
    • (2014) Nanoscale , vol.6 , pp. 8274-8282
    • Wang, M.1    Chen, Z.2    Zheng, W.3    Zhu, H.4    Lu, S.5    Ma, E.6    Tu, D.7    Zhou, S.8    Huang, M.9    Chen, X.10
  • 35
    • 84870294469 scopus 로고    scopus 로고
    • In Vivo Photodynamic Therapy Using Upconversion Nanoparticles as Remote-Controlled Nanotransducers
    • Idris, N. M.; Gnanasammandhan, M. K.; Zhang, J.; Ho, P. C.; Mahendran, R.; Zhang, Y. In Vivo Photodynamic Therapy Using Upconversion Nanoparticles as Remote-Controlled Nanotransducers Nat. Med. 2008, 18, 1580-1586 10.1038/nm.2933
    • (2008) Nat. Med. , vol.18 , pp. 1580-1586
    • Idris, N.M.1    Gnanasammandhan, M.K.2    Zhang, J.3    Ho, P.C.4    Mahendran, R.5    Zhang, Y.6
  • 36
    • 80053301640 scopus 로고    scopus 로고
    • Iridium(III) Complex-Coated Nanosystem for Ratiometric Upconversion Luminescence Bioimaging of Cyanide Anions
    • Liu, J.; Liu, Y.; Liu, Q.; Li, C.; Sun, L.; Li, F. Iridium(III) Complex-Coated Nanosystem for Ratiometric Upconversion Luminescence Bioimaging of Cyanide Anions J. Am. Chem. Soc. 2011, 133, 15276-15279 10.1021/ja205907y
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 15276-15279
    • Liu, J.1    Liu, Y.2    Liu, Q.3    Li, C.4    Sun, L.5    Li, F.6
  • 38
    • 34547486889 scopus 로고    scopus 로고
    • Titanium Dioxide Nanomaterials: Synthesis, Properties, Modifications, and Applications
    • Chen, X.; Mao, S. S. Titanium Dioxide Nanomaterials: Synthesis, Properties, Modifications, and Applications Chem. Rev. 2007, 107, 2891-2959 10.1021/cr0500535
    • (2007) Chem. Rev. , vol.107 , pp. 2891-2959
    • Chen, X.1    Mao, S.S.2
  • 39
    • 84915789762 scopus 로고    scopus 로고
    • Designing Multi-Branched Gold Nanoechinus for NIR Light Activated Dual Modal Photodynamic and Photothermal Therapy in the Second Biological Window
    • Vijayaraghavan, P.; Liu, C. H.; Vankayala, R.; Chiang, C. S.; Hwang, K. C. Designing Multi-Branched Gold Nanoechinus for NIR Light Activated Dual Modal Photodynamic and Photothermal Therapy in the Second Biological Window Adv. Mater. 2014, 26, 6689-6695 10.1002/adma.201400703
    • (2014) Adv. Mater. , vol.26 , pp. 6689-6695
    • Vijayaraghavan, P.1    Liu, C.H.2    Vankayala, R.3    Chiang, C.S.4    Hwang, K.C.5
  • 43
    • 84890922670 scopus 로고    scopus 로고
    • The role of Iron and Reactive Oxygen Species in Cell Death
    • Dixon, S. J.; Stockwell, B. R. The role of Iron and Reactive Oxygen Species in Cell Death Nat. Chem. Biol. 2014, 10, 9-17 10.1038/nchembio.1416
    • (2014) Nat. Chem. Biol. , vol.10 , pp. 9-17
    • Dixon, S.J.1    Stockwell, B.R.2
  • 44
    • 84892817037 scopus 로고    scopus 로고
    • Near-Infrared Photoregulated Drug Release in Living Tumor Tissue via Yolk-Shell Upconversion Nanocages
    • Zhao, L.; Peng, J.; Huang, Q.; Li, C.; Chen, M.; Sun, Y.; Lin, Q.; Zhu, L.; Li, F. Near-Infrared Photoregulated Drug Release in Living Tumor Tissue via Yolk-Shell Upconversion Nanocages Adv. Funct. Mater. 2014, 24, 363-371 10.1002/adfm.201302133
    • (2014) Adv. Funct. Mater. , vol.24 , pp. 363-371
    • Zhao, L.1    Peng, J.2    Huang, Q.3    Li, C.4    Chen, M.5    Sun, Y.6    Lin, Q.7    Zhu, L.8    Li, F.9
  • 46
    • 56849103566 scopus 로고    scopus 로고
    • Metabolic Insertion of Nanostructured TiO2 into the Patterned Biosilica of the Diatom Pinnularia sp. by a Two-Stage Bioreactor Cultivation Process
    • Jeffryes, C.; Gutu, T.; Jiao, J.; Rorrer, G. L. Metabolic Insertion of Nanostructured TiO2 into the Patterned Biosilica of the Diatom Pinnularia sp. by a Two-Stage Bioreactor Cultivation Process ACS Nano 2008, 2, 2103-2112 10.1021/nn800470x
    • (2008) ACS Nano , vol.2 , pp. 2103-2112
    • Jeffryes, C.1    Gutu, T.2    Jiao, J.3    Rorrer, G.L.4
  • 47
    • 33947426789 scopus 로고    scopus 로고
    • Cell-Penetrating Quantum Dots Based on Multivalent and Endosome-Disrupting Surface Coatings
    • Duan, H.; Nie, S. Cell-Penetrating Quantum Dots Based on Multivalent and Endosome-Disrupting Surface Coatings J. Am. Chem. Soc. 2007, 129, 3333-3338 10.1021/ja068158s
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 3333-3338
    • Duan, H.1    Nie, S.2
  • 48
    • 84867089289 scopus 로고    scopus 로고
    • Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics
    • Marrache, S.; Dhar, S. Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 16288-16293 10.1073/pnas.1210096109
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 16288-16293
    • Marrache, S.1    Dhar, S.2
  • 51
    • 80053929634 scopus 로고    scopus 로고
    • Emerging Nanomaterials for Targeting Subcellular Organelles
    • Huang, J. G.; Leshuk, T.; Gu, F. X. Emerging Nanomaterials for Targeting Subcellular Organelles Nano Today 2011, 6, 478-492 10.1016/j.nantod.2011.08.002
    • (2011) Nano Today , vol.6 , pp. 478-492
    • Huang, J.G.1    Leshuk, T.2    Gu, F.X.3
  • 52
    • 1842428673 scopus 로고    scopus 로고
    • Percolation and Criticality in a Mitochondrial Network
    • Aon, M. A.; Cortassa, S.; O'Rourke, B. Percolation and Criticality in a Mitochondrial Network Proc. Natl. Acad. Sci. U. S. A. 2004, 101, 4447-4452 10.1073/pnas.0307156101
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 4447-4452
    • Aon, M.A.1    Cortassa, S.2    O'Rourke, B.3
  • 54
    • 0037879052 scopus 로고    scopus 로고
    • The Mitochondrial Membrane Potential (m) in Apoptosis; An Update
    • Ly, J. D.; Grubb, D. R.; Lawen, A. The Mitochondrial Membrane Potential (m) in Apoptosis; An Update Apoptosis 2003, 8, 115-128 10.1023/A:1022945107762
    • (2003) Apoptosis , vol.8 , pp. 115-128
    • Ly, J.D.1    Grubb, D.R.2    Lawen, A.3
  • 55
    • 0035861589 scopus 로고    scopus 로고
    • Photodynamic Therapy-Induced Apoptosis in Epidermoid Carcinoma Cells. Reactive Oxygen Species and Mitochondrial Inner Membrane Permeabilization
    • Lam, M.; Oleinick, N. L.; Nieminen, A. L. Photodynamic Therapy-Induced Apoptosis in Epidermoid Carcinoma Cells. Reactive Oxygen Species and Mitochondrial Inner Membrane Permeabilization J. Biol. Chem. 2001, 276, 47379-47386 10.1074/jbc.M107678200
    • (2001) J. Biol. Chem. , vol.276 , pp. 47379-47386
    • Lam, M.1    Oleinick, N.L.2    Nieminen, A.L.3
  • 56
    • 79958792115 scopus 로고    scopus 로고
    • PH-Triggered Controlled Drug Release from Mesoporous Silica Nanoparticles via Intracelluar Dissolution of ZnO Nanolids
    • Muhammad, F.; Guo, M.; Qi, W.; Sun, F.; Wang, A.; Guo, Y.; Zhu, G. pH-Triggered Controlled Drug Release from Mesoporous Silica Nanoparticles via Intracelluar Dissolution of ZnO Nanolids J. Am. Chem. Soc. 2011, 133, 8778-8781 10.1021/ja200328s
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 8778-8781
    • Muhammad, F.1    Guo, M.2    Qi, W.3    Sun, F.4    Wang, A.5    Guo, Y.6    Zhu, G.7
  • 57
    • 84904359826 scopus 로고    scopus 로고
    • Carbon-Dot-Based Ratiometric Fluorescent Probe for Imaging and Biosensing of Superoxide Anion in Live Cells
    • Gao, X.; Ding, C.; Zhu, A.; Tian, Y. Carbon-Dot-Based Ratiometric Fluorescent Probe for Imaging and Biosensing of Superoxide Anion in Live Cells Anal. Chem. 2014, 86, 7071-7078 10.1021/ac501499y
    • (2014) Anal. Chem. , vol.86 , pp. 7071-7078
    • Gao, X.1    Ding, C.2    Zhu, A.3    Tian, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.