Trimodal Therapy: Combining Hyperthermia with Repurposed Bexarotene and Ultrasound for Treating Liver Cancer

ACS Nano

Volumn 9, Issue 11, 2015, Pages 10695-10718

  Misra, Santosh K ^a   Ghoshal, Goutam ^f   Gartia, Manas R ^a   Wu, Zhe ^b   De, Arun K ^a   Ye, Mao ^a   Bromfield, Corinne R ^c   Williams, Emery M ^f   Singh, Kuldeep ^d   Tangella, Krishnarao V ^e   Rund, Laurie ^a   Schulten, Klaus ^b,d   Schook, Lawrence B ^a,f   Ray, Partha S ^a,d   Burdette, Everette C ^f   Pan, Dipanjan ^a,b,d,g  

^a Department of Bioengineering ^*  (United States)

^b University of Illinois at Urbana Champaign   (United States)

^c Agricultural Animal Care and Use Program   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e Pathology and Internal Medicine   (United States)

^f Acoustic MedSystems   (United States)

^g CARLE FOUNDATION HOSPITAL   (United States)

Author keywords

anticancer prodrug nanobubble; drug repurposing; liver cancer; thermal ablation

Indexed keywords

ABLATION; CHEMICAL STABILITY; HYPERTHERMIA THERAPY; T-CELLS; ULTRASONICS;

ATTRACTIVE STRATEGIES; CLINICAL APPLICATION; HEPATOCELLULAR CARCINOMA; LIVER CANCERS; NANO-BUBBLE; PHYSICO-CHEMICAL CHARACTERIZATION; REPURPOSING; THERMAL ABLATION;

DISEASES;

BEXAROTENE; NANOPARTICLE; PRODRUG; RETINOID X RECEPTOR ALPHA; TETRALIN DERIVATIVE;

AGONISTS; ANIMAL; CATHETER; CHEMISTRY; DIAGNOSTIC IMAGING; DISEASE MODEL; DRUG REPOSITIONING; ECHOGRAPHY; ELECTRICITY; ELECTROPHORESIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HEP-G2 CELL LINE; HUMAN; LIVER NEOPLASMS; METABOLISM; MOLECULAR DYNAMICS; MULTIMODALITY CANCER THERAPY; PATHOLOGY; PH; PIG; QUANTUM THEORY; RAMAN SPECTROMETRY; SYNTHESIS; THERMODYNAMICS; THERMOTHERAPY; ULTRASOUND;

ANIMALS; CATHETERS; COMBINED MODALITY THERAPY; DISEASE MODELS, ANIMAL; DRUG REPOSITIONING; ELECTRICITY; ELECTROPHORESIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; HYPERTHERMIA, INDUCED; LIVER NEOPLASMS; MOLECULAR DYNAMICS SIMULATION; NANOPARTICLES; PRODRUGS; QUANTUM THEORY; RETINOID X RECEPTOR ALPHA; SPECTRUM ANALYSIS, RAMAN; SUS SCROFA; TETRAHYDRONAPHTHALENES; THERMODYNAMICS; ULTRASONICS; ULTRASONOGRAPHY;

EID: 84948404912     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b05974     Document Type: Article

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