Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome

Journal of Physiology

Volumn 593, Issue 14, 2015, Pages 3181-3197

  Pereira, Troy J ^a,b,c   Fonseca, Mario A ^a,b,c   Campbell, Kristyn E ^a,b,c   Moyce, Brittany L ^a,b,c   Cole, Laura K ^a,b,c   Hatch, Grant M ^a,b,c   Doucette, Christine A ^a,b,c   Klein, Julianne ^e   Aliani, Michel ^d   Dolinsky, Vernon W ^a,b,c  

^a Department of Pharmacology and Therapeutics ^*  (Canada)

^b Diabetes Research Envisioned and Accomplished in Manitoba (DREAM) Research Theme   (Canada)

^c Institute of Manitoba   (Canada)

^d UNIVERSITY OF MANITOBA   (Canada)

^e Diagnostic Services of Manitoba Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; INSULIN; MESSENGER RNA; NUCLEOTIDYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSPHATIDYLETHANOLAMINE; PHOSPHOETHANOLAMINE CYTIDYLYLTRANSFERASE; SUCROSE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DAM (ANIMAL); FATTY LIVER; FEMALE; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID METABOLISM; LOW FAT DIET; MALE; MATERNAL OBESITY; METABOLOME; NEWBORN; NONHUMAN; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; RAT; SUGAR INTAKE; WEIGHT GAIN; YOUNG ADULT; ADVERSE EFFECTS; ANIMAL; DIABETES, GESTATIONAL; GENETICS; LIPID DIET; LIVER; METABOLISM; OBESITY; PREGNANCY; PRENATAL EXPOSURE; SPRAGUE DAWLEY RAT;

ANIMALS; DIABETES, GESTATIONAL; DIET, HIGH-FAT; DIGLYCERIDES; FATTY LIVER; FEMALE; LIPID METABOLISM; LIVER; METABOLOME; OBESITY; PHOSPHATIDYLETHANOLAMINES; PPAR ALPHA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; SUCROSE;

EID: 84948130698     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/JP270429     Document Type: Article

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