Developmental programming by maternal insulin resistance: Hyperinsulinemia, glucose intolerance, and dysregulated lipid metabolism in male offspring of insulin-resistant mice

Diabetes

Volumn 63, Issue 2, 2014, Pages 688-700

  Isganaitis, Elvira ^a   Woo, Melissa ^a   Ma, Huijuan ^a   Chen, Michael ^a   Kong, Wen ^a   Lytras, Aristides ^a   Sales, Vicencia ^a   DeCoste Lopez, Jennifer ^a   Lee, Kyung Ju ^a   Leatherwood, Cianna ^a   Lee, Deborah ^a   Fitzpatrick, Connor ^a   Gall, Walter ^b   Watkins, Steven ^c   Patti, Mary Elizabeth ^a  

^a JOSLIN DIABETES CENTER   (United States)

^b METABOLON INC   (United States)

^c Lipomics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCEROPHOSPHATE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LEPTIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLASMINOGEN ACTIVATOR INHIBITOR 1; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR AP 2; TUMOR NECROSIS FACTOR ALPHA;

ADIPOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRTH WEIGHT; BODY WEIGHT; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HAPLOINSUFFICIENCY; HISTOLOGY; HYPERINSULINEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; LITTER SIZE; LIVER HISTOLOGY; MALE; MATERNAL INSULIN RESISTANCE; MATERNAL PLASMA; MOUSE; NONHUMAN; OBESITY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WEIGHT GAIN;

AGING; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DYSLIPIDEMIAS; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE INTOLERANCE; HAPLOTYPES; HYPERINSULINISM; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MALE; MICE; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 84893150294     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0558     Document Type: Article

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