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Volumn 5, Issue , 2015, Pages

Nuclear factor, erythroid 2-like 2-associated molecular signature predicts lung cancer survival

Author keywords

[No Author keywords available]

Indexed keywords

NFE2L2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTOME;

EID: 84948126735     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16889     Document Type: Article
Times cited : (44)

References (51)
  • 1
    • 84907907866 scopus 로고    scopus 로고
    • Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses
    • Biswas, C. et al. Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses. The Journal of biological chemistry 289, 26882-26894, doi: 10.1074/jbc.M114.567685 (2014).
    • (2014) The Journal of Biological Chemistry , vol.289 , pp. 26882-26894
    • Biswas, C.1
  • 2
    • 84885944468 scopus 로고    scopus 로고
    • The emerging role of the Nrf2-Keap1 signaling pathway in cancer
    • Jaramillo, M. C., Zhang, D. D. The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes & development 27, 2179-2191, doi: 10.1101/gad.225680.113 (2013).
    • (2013) Genes & Development , vol.27 , pp. 2179-2191
    • Jaramillo, M.C.1    Zhang, D.D.2
  • 3
    • 84872803731 scopus 로고    scopus 로고
    • Nrf2 and p53: Januses in cancer
    • Rotblat, B., Melino, G., Knight, R. A. Nrf2 and p53: Januses in cancer Oncotarget 3, 1272-1283 (2012).
    • (2012) Oncotarget , vol.3 , pp. 1272-1283
    • Rotblat, B.1    Melino, G.2    Knight, R.A.3
  • 4
    • 84864348569 scopus 로고    scopus 로고
    • Nrf2 and cancer: The good, the bad and the importance of context Nature reviews
    • Sporn, M. B., Liby, K. T. Nrf2 and cancer: the good, the bad and the importance of context. Nature reviews. Cancer 12, 564-571, doi: 10.1038/nrc3278 (2012).
    • (2012) Cancer , vol.12 , pp. 564-571
    • Sporn, M.B.1    Liby, K.T.2
  • 5
    • 0037015035 scopus 로고    scopus 로고
    • Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
    • Dinkova-Kostova, A. T. et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proceedings of the National Academy of Sciences of the United States of America 99, 11908-11913, doi: 10.1073/pnas.172398899 (2002).
    • (2002) Proceedings of the National Academy of Sciences of the United States of America , vol.99 , pp. 11908-11913
    • Dinkova-Kostova, A.T.1
  • 6
    • 1642282736 scopus 로고    scopus 로고
    • Cellular mechanisms of redox cell signalling: Role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products
    • Levonen, A. L. et al. Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. The Biochemical journal 378, 373-382, doi: 10.1042/BJ20031049 (2004).
    • (2004) The Biochemical Journal , vol.378 , pp. 373-382
    • Levonen, A.L.1
  • 7
    • 1942520367 scopus 로고    scopus 로고
    • Nrf2 signaling in coordinated activation of antioxidant gene expression
    • Jaiswal, A. K. Nrf2 signaling in coordinated activation of antioxidant gene expression. Free radical biology & medicine 36, 1199-1207, doi: 10.1016/j.freeradbiomed.2004.02.074 (2004).
    • (2004) Free Radical Biology & Medicine , vol.36 , pp. 1199-1207
    • Jaiswal, A.K.1
  • 8
    • 67649402187 scopus 로고    scopus 로고
    • The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
    • Nguyen, T., Nioi, P., Pickett, C. B. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. The Journal of biological chemistry 284, 13291-13295, doi: 10.1074/jbc.R900010200 (2009).
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 13291-13295
    • Nguyen, T.1    Nioi, P.2    Pickett, C.B.3
  • 9
    • 0029906134 scopus 로고    scopus 로고
    • Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene
    • Venugopal, R., Jaiswal, A. K. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proceedings of the National Academy of Sciences of the United States of America 93, 14960-14965 (1996).
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , pp. 14960-14965
    • Venugopal, R.1    Jaiswal, A.K.2
  • 10
    • 0032542213 scopus 로고    scopus 로고
    • Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes
    • Venugopal, R., Jaiswal, A. K. Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes. Oncogene 17, 3145-3156, doi: 10.1038/sj. onc.1202237 (1998).
    • (1998) Oncogene , vol.17 , pp. 3145-3156
    • Venugopal, R.1    Jaiswal, A.K.2
  • 11
    • 79960060305 scopus 로고    scopus 로고
    • Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
    • DeNicola, G. M. et al. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature 475, 106-109, doi: 10.1038/nature10189 (2011).
    • (2011) Nature , vol.475 , pp. 106-109
    • DeNicola, G.M.1
  • 12
    • 63549121490 scopus 로고    scopus 로고
    • Nrf2 and KEAP1 mutations: Permanent activation of an adaptive response in cancer
    • Hayes, J. D., McMahon, M. Nrf2 and KEAP1 mutations: permanent activation of an adaptive response in cancer. Trends in biochemical sciences 34, 176-188, doi: 10.1016/j.tibs.2008.12.008 (2009).
    • (2009) Trends in Biochemical Sciences , vol.34 , pp. 176-188
    • Hayes, J.D.1    McMahon, M.2
  • 13
    • 84923222319 scopus 로고    scopus 로고
    • Dual roles of Nrf2 in tumor prevention and progression: Possible implications in cancer treatment
    • Moon, E. J., Giaccia, A. Dual roles of Nrf2 in tumor prevention and progression: Possible implications in cancer treatment. Free radical biology & medicine, doi: 10.1016/j.freeradbiomed.2014.11.009 (2014).
    • (2014) Free Radical Biology & Medicine
    • Moon, E.J.1    Giaccia, A.2
  • 14
    • 33344456501 scopus 로고    scopus 로고
    • Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer
    • Padmanabhan, B. et al. Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. Molecular cell 21, 689-700, doi: 10.1016/j.molcel.2006.01.013 (2006).
    • (2006) Molecular Cell , vol.21 , pp. 689-700
    • Padmanabhan, B.1
  • 15
    • 0035853157 scopus 로고    scopus 로고
    • Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
    • Ramos-Gomez, M. et al. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proceedings of the National Academy of Sciences of the United States of America 98, 3410-3415, doi: 10.1073/pnas.051618798 (2001).
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , pp. 3410-3415
    • Ramos-Gomez, M.1
  • 16
    • 0037106099 scopus 로고    scopus 로고
    • Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
    • Thimmulappa, R. K. et al. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer research 62, 5196-5203 (2002).
    • (2002) Cancer Research , vol.62 , pp. 5196-5203
    • Thimmulappa, R.K.1
  • 17
    • 84873469216 scopus 로고    scopus 로고
    • The transcription factor NF-E2-related factor 2 (Nrf2) a protooncogene FASEB journal: Official publication of the Federation of American
    • Shelton, P., Jaiswal, A. K. The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene FASEB journal: official publication of the Federation of American Societies for Experimental Biology 27, 414-423, doi: 10.1096/fj.12-217257 (2013).
    • (2013) Societies for Experimental Biology , vol.27 , pp. 414-423
    • Shelton, P.1    Jaiswal, A.K.2
  • 18
  • 19
    • 84907337366 scopus 로고    scopus 로고
    • Cytoprotection gone astray Nrf2 and its role in cancer
    • Geismann, C., Arlt, A., Sebens, S., Schafer, H. Cytoprotection "gone astray": Nrf2 and its role in cancer. OncoTargets and therapy 7, 1497-1518, doi: 10.2147/OTT.S36624 (2014).
    • (2014) OncoTargets and Therapy , vol.7 , pp. 1497-1518
    • Geismann, C.1    Arlt, A.2    Sebens, S.3    Schafer, H.4
  • 20
    • 84902440352 scopus 로고    scopus 로고
    • Modulation of Nrf2 signaling pathway by nuclear receptors: Implications for cancer
    • Namani, A., Li, Y., Wang, X. J., Tang, X. Modulation of Nrf2 signaling pathway by nuclear receptors: implications for cancer. Biochimica et biophysica acta 1843, 1875-1885, doi: 10.1016/j.bbamcr.2014.05.003 (2014).
    • (2014) Biochimica et Biophysica Acta , vol.1843 , pp. 1875-1885
    • Namani, A.1    Li, Y.2    Wang, X.J.3    Tang, X.4
  • 21
    • 84863764614 scopus 로고    scopus 로고
    • Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming
    • Mitsuishi, Y. et al. Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer cell 22, 66-79, doi: 10.1016/j.ccr.2012.05.016 (2012).
    • (2012) Cancer Cell , vol.22 , pp. 66-79
    • Mitsuishi, Y.1
  • 22
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar, R., Domrachev, M., Lash, A. E. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic acids research 30, 207-210 (2002).
    • (2002) Nucleic Acids Research , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 24
    • 79961102335 scopus 로고    scopus 로고
    • Gene expression profiling reveals novel biomarkers in nonsmall cell lung cancer
    • Sanchez-Palencia, A. et al. Gene expression profiling reveals novel biomarkers in nonsmall cell lung cancer. International journal of cancer. Journal international du cancer 129, 355-364, doi: 10.1002/ijc.25704 (2011).
    • (2011) International Journal of Cancer. Journal International du Cancer , vol.129 , pp. 355-364
    • Sanchez-Palencia, A.1
  • 26
    • 58149343905 scopus 로고    scopus 로고
    • Prediction of recurrence-free survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expression
    • Lee, E. S. et al. Prediction of recurrence-free survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expression. Clinical cancer research : an official journal of the American Association for Cancer Research 14, 7397-7404, doi: 10.1158/1078-0432.CCR-07-4937 (2008).
    • (2008) Clinical Cancer Research An Official Journal of the American Association for Cancer Research , vol.14 , pp. 7397-7404
    • Lee, E.S.1
  • 27
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild, A. H. et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 439, 353-357, doi: 10.1038/nature04296 (2006).
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1
  • 28
    • 84866529515 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase defines critical prognostic genes of stage i lung adenocarcinoma
    • Yamauchi, M. et al. Epidermal growth factor receptor tyrosine kinase defines critical prognostic genes of stage I lung adenocarcinoma. PloS one 7, e43923, doi: 10.1371/journal.pone.0043923 (2012).
    • (2012) PloS One , vol.7 , pp. e43923
    • Yamauchi, M.1
  • 29
    • 84871959921 scopus 로고    scopus 로고
    • Biomarker discovery in non-small cell lung cancer: Integrating gene expression profiling, meta-analysis, and tissue microarray validation
    • Botling, J. et al. Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation. Clinical cancer research: an official journal of the American Association for Cancer Research 19, 194-204, doi: 10.1158/1078-0432.CCR-12-1139 (2013).
    • (2013) Clinical Cancer Research An Official Journal of the American Association for Cancer Research , vol.19 , pp. 194-204
    • Botling, J.1
  • 30
    • 84891830936 scopus 로고    scopus 로고
    • Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients
    • Der, S. D. et al. Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients. Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer 9, 59-64, doi: 10.1097/JTO.0000000000000042 (2014).
    • (2014) Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer , vol.9 , pp. 59-64
    • Der, S.D.1
  • 31
    • 80055090025 scopus 로고    scopus 로고
    • Most random gene expression signatures are significantly associated with breast cancer outcome
    • Venet, D., Dumont, J. E., Detours, V. Most random gene expression signatures are significantly associated with breast cancer outcome. PLoS computational biology 7, e1002240, doi: 10.1371/journal.pcbi.1002240 (2011).
    • (2011) PLoS Computational Biology , vol.7 , pp. e1002240
    • Venet, D.1    Dumont, J.E.2    Detours, V.3
  • 33
    • 33646160623 scopus 로고    scopus 로고
    • Inflammation a key event in cancer development
    • Lu, H., Ouyang, W., Huang, C. Inflammation, a key event in cancer development. Molecular cancer research: MCR 4, 221-233, doi: 10.1158/1541-7786.MCR-05-0261 (2006).
    • (2006) Molecular Cancer Research: MCR , vol.4 , pp. 221-233
    • Lu, H.1    Ouyang, W.2    Huang, C.3
  • 34
    • 33750885385 scopus 로고    scopus 로고
    • Dysfunctional KEAP1-Nrf2 interaction in non-small-cell lung cancer
    • Singh, A. et al. Dysfunctional KEAP1-Nrf2 interaction in non-small-cell lung cancer. PLoS medicine 3, e420, doi: 10.1371/journal.pmed.0030420 (2006).
    • (2006) PLoS Medicine , vol.3 , pp. e420
    • Singh, A.1
  • 36
    • 79952232216 scopus 로고    scopus 로고
    • Global cancer statistics. CA
    • Jemal, A. et al. Global cancer statistics. CA: a cancer journal for clinicians 61, 69-90, doi: 10.3322/caac.20107 (2011).
    • (2011) A Cancer Journal for Clinicians , vol.61 , pp. 69-90
    • Jemal, A.1
  • 37
    • 84907938125 scopus 로고    scopus 로고
    • Molecular pathology of lung cancer: Current status and future directions
    • Roh, M. S. Molecular pathology of lung cancer: current status and future directions. Tuberculosis and respiratory diseases 77, 49-54, doi: 10.4046/trd.2014.77.2.49 (2014).
    • (2014) Tuberculosis and Respiratory Diseases , vol.77 , pp. 49-54
    • Roh, M.S.1
  • 39
    • 70450223891 scopus 로고    scopus 로고
    • Common disorders are quantitative traits
    • Plomin, R., Haworth, C. M., Davis, O. S. Common disorders are quantitative traits. Nature reviews. Genetics 10, 872-878, doi: 10.1038/nrg2670 (2009).
    • (2009) Nature Reviews. Genetics , vol.10 , pp. 872-878
    • Plomin, R.1    Haworth, C.M.2    Davis, O.S.3
  • 40
    • 33947101019 scopus 로고    scopus 로고
    • Patterns of somatic mutation in human cancer genomes
    • Greenman, C. et al. Patterns of somatic mutation in human cancer genomes. Nature 446, 153-158, doi: 10.1038/nature05610 (2007).
    • (2007) Nature , vol.446 , pp. 153-158
    • Greenman, C.1
  • 42
    • 0036990103 scopus 로고    scopus 로고
    • The organ microenvironment and cancer metastasis
    • Fidler, I. J. The organ microenvironment and cancer metastasis. Differentiation; research in biological diversity 70, 498-505, doi: 10.1046/j.1432-0436.2002.700904.x (2002).
    • (2002) Differentiation; Research in Biological Diversity , vol.70 , pp. 498-505
    • Fidler, I.J.1
  • 43
    • 84867924331 scopus 로고    scopus 로고
    • The metastatic niche and stromal progression
    • Sleeman, J. P. The metastatic niche and stromal progression. Cancer metastasis reviews 31, 429-440, doi: 10.1007/s10555-012-9373-9 (2012).
    • (2012) Cancer Metastasis Reviews , vol.31 , pp. 429-440
    • Sleeman, J.P.1
  • 45
    • 84906691644 scopus 로고    scopus 로고
    • Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrencefree survival in lung and breast cancers
    • Zhou, T., Wang, T., Garcia, J. G. Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrencefree survival in lung and breast cancers. Scientific reports 4, 6107, doi: 10.1038/srep06107 (2014).
    • (2014) Scientific Reports , vol.4 , pp. 6107
    • Zhou, T.1    Wang, T.2    Garcia, J.G.3
  • 46
    • 84899419280 scopus 로고    scopus 로고
    • Genes influenced by the non-muscle isoform of Myosin light chain kinase impact human cancer prognosis
    • Zhou, T., Wang, T., Garcia, J. G. Genes influenced by the non-muscle isoform of Myosin light chain kinase impact human cancer prognosis. PloS one 9, e94325, doi: 10.1371/journal.pone.0094325 (2014).
    • (2014) PloS One , vol.9 , pp. e94325
    • Zhou, T.1    Wang, T.2    Garcia, J.G.3
  • 51
    • 21444446380 scopus 로고    scopus 로고
    • The 'miss rate' for the analysis of gene expression data
    • Taylor, J., Tibshirani, R., Efron, B. The 'miss rate' for the analysis of gene expression data. Biostatistics 6, 111-117, doi: 10.1093/biostatistics/kxh021 (2005).
    • (2005) Biostatistics , vol.6 , pp. 111-117
    • Taylor, J.1    Tibshirani, R.2    Efron, B.3


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