Integrative mouse and human studies implicate ANGPT1 and ZBTB7C as susceptibility genes to ischemic injury

Stroke

Volumn 46, Issue 12, 2015, Pages 3514-3522

  Du, Rose ^a   Zhou, Jing ^a   Lorenzano, Svetlana ^b,c   Liu, Wenming ^a,d   Charoenvimolphan, Nareerat ^a   Qian, Baogang ^a   Xu, Jun ^a,e   Wang, Jian ^a   Zhang, Xinmu ^a   Wang, Xin ^a   Berndt, Annerose ^f,g   Devan, William J ^b,h   Valant, Valerie J ^b,i   Wang, Jinyi ^d   Furie, Karen L ^j   Rosand, Jonathan ^b   Rost, Natalia ^b   Friedlander, Robert M ^g   Paigen, Beverly ^f   Weiss, Scott T ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d NORTHWEST A F UNIVERSITY   (China)

^e CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^f JACKSON LABORATORY   (United States)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^h QUINNIPIAC UNIVERSITY   (United States)

ⁱ UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^j BROWN UNIVERSITY   (United States)

more..

Author keywords

brain ischemia; cerebral infarction; genetics; models, animal; stroke

Indexed keywords

ANGIOPOIETIN 1; UNCLASSIFIED DRUG; ZINC FINGER AND BTB DOMAIN CONTAINING 7C; ZINC FINGER PROTEIN; ANGPT1 PROTEIN, HUMAN; PROTEIN; ZBTB7C PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; CLINICAL ARTICLE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INBRED STRAIN; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL DISEASE BY BODY FUNCTION; POPULATION STRUCTURE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SINGLE NUCLEOTIDE POLYMORPHISM; STROKE PATIENT; UMBILICAL VEIN ENDOTHELIAL CELL; 129 MOUSE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DBA MOUSE; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; NONOBESE DIABETIC MOUSE; PROCEDURES; SPECIES DIFFERENCE;

ANGIOPOIETIN-1; ANIMALS; BRAIN ISCHEMIA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED NOD; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; SPECIES SPECIFICITY;

EID: 84948119794     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.115.010767     Document Type: Article

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