Estrogen Receptor Folding Modulates cSrc Kinase SH2 Interaction via a Helical Binding Mode

ACS Chemical Biology

Volumn 10, Issue 11, 2015, Pages 2624-2632

  Nieto, Lidia ^a   Tharun, Inga M ^a   Balk, Mark ^a   Wienk, Hans ^b   Boelens, Rolf ^b   Ottmann, Christian ^a   Milroy, Lech Gustav ^a   Brunsveld, Luc ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; PROTEIN SH2; TYROSINE; PEPTIDE; PROTEIN BINDING; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOCHEMICAL ANALYSIS; CARBOXY TERMINAL SEQUENCE; COMPARATIVE STUDY; CONTROLLED STUDY; FLUORESCENCE POLARIZATION; HELICAL BINDING MODE; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SIMULATION; BIOLOGICAL MODEL; CHEMISTRY; FEMALE; FLUORESCENCE; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN FOLDING; SRC HOMOLOGY DOMAIN;

AMINO ACID SEQUENCE; BINDING SITES; FEMALE; FLUORESCENCE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, BIOLOGICAL; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN FOLDING; RECEPTORS, ESTROGEN; SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES;

EID: 84947976691     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b00568     Document Type: Article

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