Conformational determinants of phosphotyrosine peptides complexed with the Src SH2 domain

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Nachman, Joseph ^a   Gish, Gerry ^b   Virag, Cristina ^b   Pawson, Tony ^b   Pomès, Régis ^a,c   Pai, Emil ^a,d,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; ISOLEUCINE; LIGAND; PHOSPHOPEPTIDE; PHOSPHOTYROSINE; POLYPEPTIDE; PEPTIDE;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DRUG DESIGN; FLUORESCENCE POLARIZATION; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; SIMULATION; SRC HOMOLOGY DOMAIN; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMISTRY; HYDROPHOBICITY; METABOLISM; MOLECULAR DYNAMICS; TEMPERATURE; THERMODYNAMICS;

AMINO ACID SEQUENCE; HYDROPHOBICITY; MOLECULAR DYNAMICS SIMULATION; PEPTIDES; PHOSPHOTYROSINE; PROTEIN BINDING; SRC HOMOLOGY DOMAINS; TEMPERATURE; THERMODYNAMICS;

EID: 77955295230     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011215     Document Type: Article

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