The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer

Nature Genetics

Volumn 48, Issue 1, 2015, Pages 53-58

  Siprashvili, Zurab ^a   Webster, Dan E ^a   Johnston, Danielle ^a   Shenoy, Rajani M ^a   Ungewickell, Alexander J ^a   Bhaduri, Aparna ^a   Flockhart, Ross ^a   Zarnegar, Brian J ^a   Che, Yonglu ^a   Meschi, Francesca ^a   Puglisi, Joseph D ^a   Khavari, Paul A ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RNA BINDING PROTEIN; SMALL NUCLEOLAR RNA; SNORD50A RNA; SNORD50B RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA; RAS PROTEIN;

ARTICLE; BIOLOGICAL ACTIVITY; BREAST ADENOCARCINOMA; CANCER SURVIVAL; CARCINOGENESIS; COLON CANCER; FARNESYLATION; GENE DELETION; GENE LOCUS; GENE LOSS; GENE MUTATION; GENETIC ASSOCIATION; LYMPHOMA; MELANOMA; MELANOMA CELL; NEOPLASM; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN PRENYLATION; RNA ANALYSIS; RNA SEQUENCE; SIGNAL TRANSDUCTION; ANIMAL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DRUG SCREENING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MORTALITY; MUTATION; NONOBESE DIABETIC MOUSE; PRENYLATION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANOSINE TRIPHOSPHATE; HUMANS; MICE, INBRED NOD; MUTATION; NEOPLASMS; PRENYLATION; RAS PROTEINS; RNA, SMALL NUCLEOLAR; RNA, UNTRANSLATED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84947967845     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3452     Document Type: Article

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