In HIV-positive patients, myeloid-derived suppressor cells induce T-cell anergy by suppressing CD3 expression through ELF-1 inhibition

AIDS

Volumn 29, Issue 18, 2015, Pages 2397-2407

  Tumino, Nicola ^a   Turchi, Federica ^a   Meschi, Silvia ^a   Lalle, Eleonora ^a   Bordoni, Veronica ^a   Casetti, Rita ^a   Agrati, Chiara ^a   Cimini, Eleonora ^a   Montesano, Carla ^a   Colizzic, Vittorio ^a   Martini, Federico ^a   Sacchi, Alessandra ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

CD3; HIV; HIV specific T cell response immune suppression; MDSC; T cells; T cells

Indexed keywords

CD3 ANTIGEN; CD3ZETA ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; MESSENGER RNA; TRANSCRIPTION FACTOR ELF 1; UNCLASSIFIED DRUG; CD3 ANTIGEN, ZETA CHAIN; ELF1 PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CONTACT; CLONAL ANERGY; CONTROLLED STUDY; DONOR; FLOW CYTOMETRY; GAMMA DELTA T LYMPHOCYTE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; MAJOR CLINICAL STUDY; MYELOID DERIVED SUPPRESSOR CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SUPPRESSOR CELL; UPREGULATION; WESTERN BLOTTING; ADOLESCENT; ADULT; AGED; BIOSYNTHESIS; DOWN REGULATION; FEMALE; GENE EXPRESSION PROFILING; IMMUNOLOGY; IMMUNOPHENOTYPING; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; T LYMPHOCYTE; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD3; BLOTTING, WESTERN; CLONAL ANERGY; DOWN-REGULATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HIV INFECTIONS; HUMANS; IMMUNOPHENOTYPING; MALE; MIDDLE AGED; NUCLEAR PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; YOUNG ADULT;

EID: 84947868136     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0000000000000871     Document Type: Article

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