Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencing

Oncotarget

Volumn 6, Issue 35, 2015, Pages 37169-37184

  Tang, Man Hung Eric ^a   Dahlgren, Malin ^a   Brueffer, Christian ^a   Tjitrowirjo, Tamara ^a   Winter, Christof ^a   Chen, Yilun ^a   Olsson, Eleonor ^a   Wang, Kun ^a   Törngren, Therese ^a   Sjöström, Martin ^a   Grabau, Dorthe ^b   Bendahl, Pär Ola ^a   Rydén, Lisa ^a   Niméus, Emma ^a   Saal, Lao H ^a   Borg, Åke ^a   Gruvberger Saal, Sofia K ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Breast cancer; Chromosomal rearrangements; Chromothripsis; Metastasis; Whole genome sequencing

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; MESSENGER RNA; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER PATIENT; CARCINOGENESIS; CHROMOSOME REARRANGEMENT; CHROMOSOME STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DISTANT METASTASIS; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HUMAN; PRIMARY TUMOR; AGED; BREAST TUMOR; CHROMOSOME ABERRATION; COMPARATIVE STUDY; FEMALE; GENE REARRANGEMENT; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN CHROMOSOME; HUMAN GENOME; METASTASIS; MIDDLE AGED; PATHOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; BIOMARKERS, TUMOR; BREAST NEOPLASMS; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN; FEMALE; GENE REARRANGEMENT; GENOME, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MIDDLE AGED; NEOPLASM METASTASIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84947785184     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5951     Document Type: Article

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