Non-cultured dermal-derived mesenchymal cells attenuate sepsis induced by cecal ligation and puncture in mice

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Wang, Yu ^a   Tan, Li ^a   Jin, Jie ^b   Sun, Huiqin ^a   Chen, Zelin ^a   Tan, Xu ^a   Su, Yongping ^a   Shi, Chunmeng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LIPOPOLYSACCHARIDE; MICRORNA;

ADVERSE EFFECTS; ANIMAL; BLOOD; C57BL MOUSE; CECUM; CELL CULTURE; CELL MOTION; COCULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DERMIS; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GENETICS; HUMAN; INJURIES; LIGATION; MACROPHAGE; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; NEWBORN; PHAGOCYTOSIS; PROCEDURES; PUNCTURE; SEPSIS; SURGERY;

ANIMALS; ANIMALS, NEWBORN; CECUM; CELL MOVEMENT; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOKINES; DERMIS; GENE EXPRESSION PROFILING; GENE ONTOLOGY; HUMANS; LIGATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE, INBRED C57BL; MICRORNAS; MICROSCOPY, CONFOCAL; PHAGOCYTOSIS; PUNCTURES; SEPSIS;

EID: 84947746058     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16973     Document Type: Article

References (36)

1. Cribbs, S. K. et al. Circulating endothelial progenitor cells inversely associate with organ dysfunction in sepsis. Intensive Care Med 38, 429-436, doi: 10.1007/s00134-012-2480-9 (2012).
2. Angus, D. C., Wax, R. S. Epidemiology of sepsis: an update. Crit Care Med 29, S109-116 (2001).
3. Lin, H. Sepsis-Challenges and Strategies. Chinese Critical Care Medicine, 325-327 (2004).
4. Angus, D. C. et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 29, 1303-1310 (2001).
5. Clark, M. A. et al. Effect of a chimeric antibody to tumor necrosis factor-alpha on cytokine and physiologic responses in patients with severe sepsis-a randomized, clinical trial. Crit Care Med 26, 1650-1659 (1998).
6. Reinhart, K. et al. Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study. Crit Care Med 29, 765-769 (2001).
7. Fisher, C. J., Jr. et al. Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group. JAMA 271, 1836-1843 (1994).
8. Albrecht, D. M. et al. Efficacy and Safety of the Platelet-Activating Factor Receptor Antagonist BN 52021 (Ginkgolide B) in Patients with Severe Sepsis: A Randomised, Double-Blind, Placebo-Controlled, Multicentre Trial. Clin Drug Investig 24, 137-147, doi: 2432 [pii] (2004).
9. Dhainaut, J. F. et al. Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group. Crit Care Med 26, 1963-1971 (1998).
10. Fletcher, A. L. et al. Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis. Sci Transl Med 6, 249ra109, doi: 6/249/249ra109 [pii]10.1126/scitranslmed.3009377 (2014).
11. Le Blanc, K. et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363, 1439-1441 (2004).
12. Xu, J. et al. Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol 293, L131-141 (2007).
13. Gupta, N. et al. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol 179, 1855-1863 (2007).
14. Ylostalo, J. H., Bartosh, T. J., Coble, K., Prockop, D. J. Human mesenchymal stem/stromal cells cultured as spheroids are selfactivated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. Stem Cells 30, 2283-2296, doi: 10.1002/stem.1191 (2012).
15. Gao, L. et al. The immunosuppressive properties of non-cultured dermal-derived mesenchymal stromal cells and the control of graft-versus-host disease. Biomaterials 35, 3582-3588, doi:S0142-9612(14)00010-6 [pii]10.1016/j.biomaterials.2014.01.008 (2014).
16. Rittirsch, D., Huber-Lang, M. S., Flierl, M. A., Ward, P. A. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 4, 31-36, doi: nprot.2008.214 [pii]10.1038/nprot.2008.214 (2009).
17. Zhang, C. et al. Labeling stem cells with a near-infrared fluorescent heptamethine dye for noninvasive optical tracking. Cell Transplant 20, 741-751, doi: ct0155zhang [pii]10.3727/096368910X536536 (2011).
18. Yang, K. Y. et al. IV delivery of induced pluripotent stem cells attenuates endotoxin-induced acute lung injury in mice. Chest 140, 1243-1253, doi: chest.11-0539 [pii]10.1378/chest. 11-0539 (2011).
19. Tsai, W. C. et al. MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma. Hepatology 49, 1571-1582, doi: 10.1002/hep.22806 (2009).
20. Moore, C. C., McKillop, I. H., Huynh, T. MicroRNA expression following activated protein C treatment during septic shock. J Surg Res 182, 116-126, doi: S0022-4804(12)00717-2 [pii]10.1016/j.jss.2012.07.063 (2013).
21. Huang da, W., Sherman, B. T., Lempicki, R. A. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37, 1-13, doi: gkn923 [pii]10.1093/nar/gkn923 (2009).
22. Pavelka, K. et al. The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled study with primary end points at two months after the end of a three-month treatment period. Arthritis Rheum 56, 4055-4064, doi: 10.1002/art.23056 (2007).
23. Li, L., Fukunaga-Kalabis, M., Herlyn, M. Isolation, characterization, and differentiation of human multipotent dermal stem cells. Methods Mol Biol 989, 235-246, doi: 10.1007/978-1-62703-330-5-18 (2013).
24. Shi, C. M. et al. Transplantation of dermal multipotent cells promotes the hematopoietic recovery in sublethally irradiated rats. J Radiat Res 45, 19-24 (2004).
25. Ortiz, L. A. et al. Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury. Proc Natl Acad Sci USA 104, 11002-11007, doi: 0704421104 [pii]10.1073/pnas.0704421104 (2007).
26. Aicher, A. et al. Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling. Circulation 107, 2134-2139, doi: 10.1161/01.CIR.0000062649.63838.C901.CIR.0000062649.63838.C9 [pii] (2003).
27. Mahmood, A., Lu, D., Lu, M., Chopp, M. Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells. Neurosurgery 53, 697-702, discussion 702-693 (2003).
28. Li, Z. H. et al. Intravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head. Int J Med Sci 8, 74-83 (2011).
29. Hauger, O. et al. MR evaluation of the glomerular homing of magnetically labeled mesenchymal stem cells in a rat model of nephropathy. Radiology 238, 200-210, doi: 238/1/200 [pii]10.1148/radiol.2381041668 (2006).
30. Li, C., Yang, G., Ruan, J. Sphingosine kinase-1/sphingosine-1-phosphate receptor type 1 signalling axis is induced by transforming growth factor-beta1 and stimulates cell migration in RAW264.7 macrophages. Biochem Biophys Res Commun 426, 415-420, doi: S0006-291X(12)01674-9 [pii]10.1016/j.bbrc.2012.08.108 (2012).
31. Nemeth, K. et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 15, 42-49, doi: nm.1905 [pii]10.1038/nm.1905 (2009).
32. Mei, S. H. et al. Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis. Am J Respir Crit Care Med 182, 1047-1057, doi: 201001-0010OC [pii]10.1164/rccm.201001-0010OC (2010).
33. Linch, S. N. et al. Interleukin 5 is protective during sepsis in an eosinophil-independent manner. Am J Respir Crit Care Med 186, 246-254, doi: rccm.201201-0134OC [pii]10.1164/rccm.201201-0134OC (2012).
34. Hayes, M., Curley, G., Ansari, B., Laffey, J. G. Clinical review: Stem cell therapies for acute lung injury/acute respiratory distress syndrome-hope or hype Crit Care 16, 205, doi: cc10570 [pii]10.1186/cc10570 (2012).
35. Wang, X. et al. Loss of duplexmiR-223 (5p and 3p) aggravates myocardial depression and mortality in polymicrobial sepsis. Biochim Biophys Acta 1842, 701-711, doi: S0925-4439(14)00028-3 [pii]10.1016/j.bbadis.2014.01.012 (2014).
36. Wu, S. C. et al. Profiling circulating microRNA expression in experimental sepsis using cecal ligation and puncture. PLoS One 8, e77936, doi:10.1371/journal.pone.0077936PONE-D-13-21439 [pii] (2013).