Confirmatory platelet-activating factor receptor antagonist trial in patients with severe Gram-negative bacterial sepsis: A phase III, randomized, double-blind, placebo-controlled, multicenter trial

Critical Care Medicine

Volumn 26, Issue 12, 1998, Pages 1963-1971

  Dhainaut, Jean François A ^a   Tenaillon, Alain ^b   Hemmer, Margaret ^c   Damas, Pierre ^d   Le Tulzo, Yves ^e   Radermacher, Peter ^f   Schaller, Marie Denise ^g   Sollet, Jean Pierre ^h   Wolff, Michel ⁱ   Holzapfel, Laurent ^j   Zeni, Fabrice ^k   Vedrinne, Jean Marc ^l   De Vathaire, Florent ^m   Gourlay, Marie Laurence ⁿ   Guinot, Philippe ⁿ   Mira, Jean Paul ^a  

^a Cochin Port Roy University Hospital ^*  (France)

^b L Michel University Hospital   (France)

^c University Hospitals   (Luxembourg)

^d UNIVERSITY OF LIÈGE   (Belgium)

^e PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^f UNIVERSITY HOSPITAL ULM   (Germany)

^g LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^h CENTRE HOSPITALIER VICTOR DUPOUY   (France)

ⁱ BICHAT HOSPITAL   (France)

^j Bourg en Bresse Hospital   (France)

^k SERVICE DE NEUROLOGIE   (France)

^l EDOUARD HERRIOT HOSPITAL   (France)

^m INSTITUT GUSTAVE ROUSSY   (France)

ⁿ IPSEN   (France)

more..

Author keywords

Clinical trials; Critical illness; Gram negative bacterial infection; Inflammation; Mortality rate; Multiple organ failure; Platelet activating factor; Randomized controlled trials; Sepsis; Sepsis syndrome; Septic shock

Indexed keywords

GINKGOLIDE B; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST;

BACTERICIDAL ACTIVITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; GRAM NEGATIVE INFECTION; HUMAN; MAJOR CLINICAL STUDY; MORTALITY; MULTICENTER STUDY; MULTIPLE ORGAN FAILURE; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; REVIEW;

ADULT; AGED; ANALYSIS OF VARIANCE; APACHE; DITERPENES; DOUBLE-BLIND METHOD; FREE RADICAL SCAVENGERS; GINKGOLIDES; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; LACTONES; MIDDLE AGED; PLATELET ACTIVATING FACTOR; PROSPECTIVE STUDIES; SEPSIS; SURVIVAL ANALYSIS;

EID: 0032433468     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199812000-00021     Document Type: Review

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