메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

Mutant cohesin affects RNA polymerase II regulation in Cornelia de Lange syndrome

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; NONHISTONE PROTEIN; PROTEIN BINDING; RNA POLYMERASE II; STRUCTURAL MAINTENANCE OF CHROMOSOME PROTEIN 1;

EID: 84947573452     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16803     Document Type: Article
Times cited : (38)

References (57)
  • 1
    • 73349127026 scopus 로고    scopus 로고
    • Cohesin: Its roles and mechanisms
    • Nasmyth, K., Haering, C. H. Cohesin: its roles and mechanisms. Annu Rev Genet 43, 525-558 (2009).
    • (2009) Annu Rev Genet , vol.43 , pp. 525-558
    • Nasmyth, K.1    Haering, C.H.2
  • 2
    • 84862202409 scopus 로고    scopus 로고
    • In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex
    • Bermudez, V. P. et al. In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex. Proc Natl Acad Sci USA 109, 9366-9371 (2012).
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 9366-9371
    • Bermudez, V.P.1
  • 3
    • 84857189905 scopus 로고    scopus 로고
    • Isolated NIBPL missense mutations that cause Cornelia de Lange syndrome alter MAU2 interaction
    • Braunholz, D. et al. Isolated NIBPL missense mutations that cause Cornelia de Lange syndrome alter MAU2 interaction. Eur J Hum Genet 20, 271-276 (2012).
    • (2012) Eur J Hum Genet , vol.20 , pp. 271-276
    • Braunholz, D.1
  • 4
    • 33747368147 scopus 로고    scopus 로고
    • Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance
    • Seitan, V. C. et al. Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance. PLoS Biol 4, e242 (2006).
    • (2006) PLoS Biol , vol.4 , pp. e242
    • Seitan, V.C.1
  • 5
    • 0037133040 scopus 로고    scopus 로고
    • Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion
    • Ivanov, D. et al. Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion. Curr Biol 12, 323-328 (2002).
    • (2002) Curr Biol , vol.12 , pp. 323-328
    • Ivanov, D.1
  • 6
    • 0033082232 scopus 로고    scopus 로고
    • Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery
    • Skibbens, R. V., Corson, L. B., Koshland, D., Hieter, P. Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery. Genes Dev 13, 307-319 (1999).
    • (1999) Genes Dev , vol.13 , pp. 307-319
    • Skibbens, R.V.1    Corson, L.B.2    Koshland, D.3    Hieter, P.4
  • 7
    • 0033083727 scopus 로고    scopus 로고
    • Yeast cohesin complex requires a conserved protein Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication
    • Toth, A. et al. Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication. Genes Dev 13, 320-333 (1999).
    • (1999) Genes Dev , vol.13 , pp. 320-333
    • Toth, A.1
  • 8
    • 33845447400 scopus 로고    scopus 로고
    • Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase
    • Gandhi, R., Gillespie, P. J., Hirano, T. Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Curr Biol 16, 2406-2417 (2006).
    • (2006) Curr Biol , vol.16 , pp. 2406-2417
    • Gandhi, R.1    Gillespie, P.J.2    Hirano, T.3
  • 9
    • 33751237384 scopus 로고    scopus 로고
    • Wapl controls the dynamic association of cohesin with chromatin
    • Kueng, S. et al. Wapl controls the dynamic association of cohesin with chromatin. Cell 127, 955-967 (2006).
    • (2006) Cell , vol.127 , pp. 955-967
    • Kueng, S.1
  • 10
    • 79953162010 scopus 로고    scopus 로고
    • Cohesin: Genomic insights into controlling gene transcription and development
    • Dorsett, D. Cohesin: genomic insights into controlling gene transcription and development. Curr Opin Genet Dev 21, 199-206 (2011).
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 199-206
    • Dorsett, D.1
  • 11
    • 77952729734 scopus 로고    scopus 로고
    • The expanding universe of cohesin functions: A new genome stability caretaker involved in human disease and cancer
    • Mannini, L., Menga, S., Musio, A. The expanding universe of cohesin functions: a new genome stability caretaker involved in human disease and cancer. Hum Mutat 31, 623-630 (2010).
    • (2010) Hum Mutat , vol.31 , pp. 623-630
    • Mannini, L.1    Menga, S.2    Musio, A.3
  • 12
    • 84875127327 scopus 로고    scopus 로고
    • CTCF and cohesin: Linking gene regulatory elements with their targets
    • Merkenschlager, M., Odom, D. T. CTCF and cohesin: linking gene regulatory elements with their targets. Cell 152, 1285-1297 (2013).
    • (2013) Cell , vol.152 , pp. 1285-1297
    • Merkenschlager, M.1    Odom, D.T.2
  • 13
    • 67650529804 scopus 로고    scopus 로고
    • Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins
    • Schaaf, C. A. et al. Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins. PLoS One 4, e6202 (2009).
    • (2009) PLoS One , vol.4 , pp. e6202
    • Schaaf, C.A.1
  • 14
    • 38849121606 scopus 로고    scopus 로고
    • Cohesins functionally associate with CTCF on mammalian chromosome arms
    • Parelho, V. et al. Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell 132, 422-433 (2008).
    • (2008) Cell , vol.132 , pp. 422-433
    • Parelho, V.1
  • 15
    • 39449111307 scopus 로고    scopus 로고
    • Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators
    • Stedman, W. et al. Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. EMBO J 27, 654-666 (2008).
    • (2008) EMBO J , vol.27 , pp. 654-666
    • Stedman, W.1
  • 16
    • 46149113242 scopus 로고    scopus 로고
    • CTCF physically links cohesin to chromatin
    • Rubio, E. D. et al. CTCF physically links cohesin to chromatin. Proc Natl Acad Sci USA 105, 8309-8314 (2008).
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8309-8314
    • Rubio, E.D.1
  • 17
    • 39149121436 scopus 로고    scopus 로고
    • Cohesin mediates transcriptional insulation by CCCTC-binding factor
    • Wendt, K. S. et al. Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature 451, 796-801 (2008).
    • (2008) Nature , vol.451 , pp. 796-801
    • Wendt, K.S.1
  • 18
    • 38349177548 scopus 로고    scopus 로고
    • Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome
    • Misulovin, Z. et al. Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome. Chromosoma 117, 89-102 (2008).
    • (2008) Chromosoma , vol.117 , pp. 89-102
    • Misulovin, Z.1
  • 19
    • 77957139539 scopus 로고    scopus 로고
    • Mediator and cohesin connect gene expression and chromatin architecture
    • Kagey, M. H. et al. Mediator and cohesin connect gene expression and chromatin architecture. Nature 467, 430-435 (2010).
    • (2010) Nature , vol.467 , pp. 430-435
    • Kagey, M.H.1
  • 20
    • 84868325694 scopus 로고    scopus 로고
    • Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules
    • Faure, A. J. et al. Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules. Genome Res 22, 2163-2175 (2012).
    • (2012) Genome Res , vol.22 , pp. 2163-2175
    • Faure, A.J.1
  • 21
    • 80052042965 scopus 로고    scopus 로고
    • A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation
    • Seitan, V. C. et al. A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature 476, 467-471 (2011).
    • (2011) Nature , vol.476 , pp. 467-471
    • Seitan, V.C.1
  • 22
    • 84876010302 scopus 로고    scopus 로고
    • Genome-wide control of RNA polymerase II activity by cohesin
    • Schaaf, C. A. et al. Genome-wide control of RNA polymerase II activity by cohesin. PLoS Genet 9, e1003382 (2013).
    • (2013) PLoS Genet , vol.9 , pp. e1003382
    • Schaaf, C.A.1
  • 23
    • 2642542322 scopus 로고    scopus 로고
    • Cornelia de Lange syndrome is caused by mutations in NIPBL the human homolog of Drosophila melanogaster Nipped-B
    • Krantz, I. D. et al. Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B. Nat Genet 36, 631-635 (2004).
    • (2004) Nat Genet , vol.36 , pp. 631-635
    • Krantz, I.D.1
  • 24
    • 2642565901 scopus 로고    scopus 로고
    • NIPBL encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B is mutated in Cornelia de Lange syndrome
    • Tonkin, E. T., Wang, T. J., Lisgo, S., Bamshad, M. J., Strachan, T. NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome. Nat Genet 36, 636-641 (2004).
    • (2004) Nat Genet , vol.36 , pp. 636-641
    • Tonkin, E.T.1    Wang, T.J.2    Lisgo, S.3    Bamshad, M.J.4    Strachan, T.5
  • 25
    • 33646379870 scopus 로고    scopus 로고
    • X-linked Cornelia de Lange syndrome owing to SMC1L1 mutations
    • Musio, A. et al. X-linked Cornelia de Lange syndrome owing to SMC1L1 mutations. Nat Genet 38, 528-530 (2006).
    • (2006) Nat Genet , vol.38 , pp. 528-530
    • Musio, A.1
  • 26
    • 33847196427 scopus 로고    scopus 로고
    • Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation
    • Deardorff, M. A. et al. Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation. Am J Hum Genet 80, 485-494 (2007).
    • (2007) Am J Hum Genet , vol.80 , pp. 485-494
    • Deardorff, M.A.1
  • 27
    • 84866183822 scopus 로고    scopus 로고
    • HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle
    • Deardorff, M. A. et al. HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature 489, 313-317 (2012).
    • (2012) Nature , vol.489 , pp. 313-317
    • Deardorff, M.A.1
  • 28
    • 84862142852 scopus 로고    scopus 로고
    • RAD21 mutations cause a human cohesinopathy
    • Deardorff, M. A. et al. RAD21 mutations cause a human cohesinopathy. Am J Hum Genet 90, 1014-1027 (2012).
    • (2012) Am J Hum Genet , vol.90 , pp. 1014-1027
    • Deardorff, M.A.1
  • 29
    • 84887615981 scopus 로고    scopus 로고
    • Mutation spectrum and genotype-phenotype correlation in Cornelia de Lange syndrome
    • Mannini, L., Cucco, F., Quarantotti, V., Krantz, I. D., Musio, A. Mutation spectrum and genotype-phenotype correlation in Cornelia de Lange syndrome. Hum Mutat 34, 1589-1596 (2013).
    • (2013) Hum Mutat , vol.34 , pp. 1589-1596
    • Mannini, L.1    Cucco, F.2    Quarantotti, V.3    Krantz, I.D.4    Musio, A.5
  • 30
    • 70349878942 scopus 로고    scopus 로고
    • Premature chromatid separation is not a useful diagnostic marker for Cornelia de Lange syndrome
    • Castronovo, P. et al. Premature chromatid separation is not a useful diagnostic marker for Cornelia de Lange syndrome. Chromosome Res 17, 763-771 (2009).
    • (2009) Chromosome Res , vol.17 , pp. 763-771
    • Castronovo, P.1
  • 31
    • 58749104967 scopus 로고    scopus 로고
    • Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA
    • Revenkova, E. et al. Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA. Hum Mol Genet 18, 418-427 (2009).
    • (2009) Hum Mol Genet , vol.18 , pp. 418-427
    • Revenkova, E.1
  • 32
    • 1842557791 scopus 로고    scopus 로고
    • Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene
    • Rollins, R. A., Korom, M., Aulner, N., Martens, A., Dorsett, D. Drosophila nipped-B protein supports sister chromatid cohesion and opposes the stromalin/Scc3 cohesion factor to facilitate long-range activation of the cut gene. Mol Cell Biol 24, 3100-3111 (2004).
    • (2004) Mol Cell Biol , vol.24 , pp. 3100-3111
    • Rollins, R.A.1    Korom, M.2    Aulner, N.3    Martens, A.4    Dorsett, D.5
  • 33
    • 70349690201 scopus 로고    scopus 로고
    • Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/) mouse a model of Cornelia de Lange Syndrome
    • Kawauchi, S. et al. Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/) mouse, a model of Cornelia de Lange Syndrome. PLoS Genet 5, e1000650 (2009).
    • (2009) PLoS Genet , vol.5 , pp. e1000650
    • Kawauchi, S.1
  • 34
    • 66249144416 scopus 로고    scopus 로고
    • Transcriptional dysregulation in NIPBL and cohesin mutant human cells
    • Liu, J. et al. Transcriptional dysregulation in NIPBL and cohesin mutant human cells. PLoS Biol 7, e1000119 (2009).
    • (2009) PLoS Biol , vol.7 , pp. e1000119
    • Liu, J.1
  • 35
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray, S. J. Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 7, 678-689 (2006).
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 36
  • 37
    • 78650679999 scopus 로고    scopus 로고
    • An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates
    • Guo, T. et al. An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. Nat Neurosci 14, 31-36 (2011).
    • (2011) Nat Neurosci , vol.14 , pp. 31-36
    • Guo, T.1
  • 38
    • 0036158262 scopus 로고    scopus 로고
    • A 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly
    • Goodman, F. R., Majewski, F., Collins, A. L., Scambler, P. J. A 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly. Am J Hum Genet 70, 547-555 (2002).
    • (2002) Am J Hum Genet , vol.70 , pp. 547-555
    • Goodman, F.R.1    Majewski, F.2    Collins, A.L.3    Scambler, P.J.4
  • 39
    • 84883450963 scopus 로고    scopus 로고
    • Genetic dissection of ventral folding morphogenesis in mouse: Embryonic visceral endoderm-supplied BMP2 positions head and heart
    • Gavrilov, S., Lacy, E. Genetic dissection of ventral folding morphogenesis in mouse: embryonic visceral endoderm-supplied BMP2 positions head and heart. Curr Opin Genet Dev 23, 461-469 (2013).
    • (2013) Curr Opin Genet Dev , vol.23 , pp. 461-469
    • Gavrilov, S.1    Lacy, E.2
  • 40
    • 84860539709 scopus 로고    scopus 로고
    • A unique role of cohesin-SA1 in gene regulation and development
    • Remeseiro, S., Cuadrado, A., Gomez-Lopez, G., Pisano, D. G., Losada, A. A unique role of cohesin-SA1 in gene regulation and development. EMBO J 31, 2090-2102 (2012).
    • (2012) EMBO J , vol.31 , pp. 2090-2102
    • Remeseiro, S.1    Cuadrado, A.2    Gomez-Lopez, G.3    Pisano, D.G.4    Losada, A.5
  • 41
    • 84910624115 scopus 로고    scopus 로고
    • Stage-specific binding profiles of cohesin in resting and activated B lymphocytes suggest a role for cohesin in immunoglobulin class switching and maturation
    • Gunal-Sadik, G. et al. Stage-specific binding profiles of cohesin in resting and activated B lymphocytes suggest a role for cohesin in immunoglobulin class switching and maturation. PLoS One 9, e111748 (2014).
    • (2014) PLoS One , vol.9 , pp. e111748
    • Gunal-Sadik, G.1
  • 42
    • 0030960672 scopus 로고    scopus 로고
    • Transcriptional activation by recruitment
    • Ptashne, M., Gann, A. Transcriptional activation by recruitment. Nature 386, 569-577 (1997).
    • (1997) Nature , vol.386 , pp. 569-577
    • Ptashne, M.1    Gann, A.2
  • 43
    • 70249104647 scopus 로고    scopus 로고
    • Defining mechanisms that regulate RNA polymerase II transcription in vivo
    • Fuda, N. J., Ardehali, M. B., Lis, J. T. Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature 461, 186-192 (2009).
    • (2009) Nature , vol.461 , pp. 186-192
    • Fuda, N.J.1    Ardehali, M.B.2    Lis, J.T.3
  • 44
    • 80053581321 scopus 로고    scopus 로고
    • The dark side of cohesin: The carcinogenic point of view
    • Mannini, L., Musio, A. The dark side of cohesin: the carcinogenic point of view. Mutat Res 728, 81-87 (2011).
    • (2011) Mutat Res , vol.728 , pp. 81-87
    • Mannini, L.1    Musio, A.2
  • 45
    • 84901735084 scopus 로고    scopus 로고
    • A cohesin-independent role for NIPBL at promoters provides insights in CdLS
    • Zuin, J. et al. A cohesin-independent role for NIPBL at promoters provides insights in CdLS. PLoS Genet 10, e1004153 (2014).
    • (2014) PLoS Genet , vol.10 , pp. e1004153
    • Zuin, J.1
  • 46
    • 84884730929 scopus 로고    scopus 로고
    • Regional chromatin decompaction in Cornelia de Lange syndrome associated with NIPBL disruption can be uncoupled from cohesin and CTCF
    • Nolen, L. D., Boyle, S., Ansari, M., Pritchard, E., Bickmore, W. A. Regional chromatin decompaction in Cornelia de Lange syndrome associated with NIPBL disruption can be uncoupled from cohesin and CTCF. Hum Mol Genet 22, 4180-4193 (2013).
    • (2013) Hum Mol Genet , vol.22 , pp. 4180-4193
    • Nolen, L.D.1    Boyle, S.2    Ansari, M.3    Pritchard, E.4    Bickmore, W.A.5
  • 47
    • 84870863653 scopus 로고    scopus 로고
    • Proteomic profile identifies dysregulated pathways in Cornelia de Lange syndrome cells with distinct mutations in SMC1A and SMC3 genes
    • Gimigliano, A. et al. Proteomic profile identifies dysregulated pathways in Cornelia de Lange syndrome cells with distinct mutations in SMC1A and SMC3 genes. J Proteome Res 11, 6111-6123 (2012).
    • (2012) J Proteome Res , vol.11 , pp. 6111-6123
    • Gimigliano, A.1
  • 48
    • 84925840671 scopus 로고    scopus 로고
    • Germline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesin
    • Izumi, K. et al. Germline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesin. Nat Genet 47, 338-344 (2015).
    • (2015) Nat Genet , vol.47 , pp. 338-344
    • Izumi, K.1
  • 50
    • 75949126139 scopus 로고    scopus 로고
    • AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia
    • Lin, C. et al. AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Molecular Cell 37, 429-437 (2010).
    • (2010) Molecular Cell , vol.37 , pp. 429-437
    • Lin, C.1
  • 51
    • 84355166398 scopus 로고    scopus 로고
    • SMC1A codon 496 mutations affect the cellular response to genotoxic treatments
    • Mannini, L. et al. SMC1A codon 496 mutations affect the cellular response to genotoxic treatments. Am J Med Genet A 158A, 224-228 (2012).
    • (2012) Am J Med Genet A 158A , pp. 224-228
    • Mannini, L.1
  • 53
    • 80255127234 scopus 로고    scopus 로고
    • Cutadapt removes adapter sequences from high-throughput sequencing reads
    • Martin, M. Cutadapt removes adapter sequences from high-throughput sequencing reads. EMBnet. journal 17, 10-12 (2011).
    • (2011) EMBnet. Journal , vol.17 , pp. 10-12
    • Martin, M.1
  • 54
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead, B., Trapnell, C., Pop, M., Salzberg, S. L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10, R25 (2009).
    • (2009) Genome Biol , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 55
    • 53849146020 scopus 로고    scopus 로고
    • Model-based analysis of ChIP-Seq (MACS)
    • Zhang, Y. et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol 9, R137 (2008).
    • (2008) Genome Biol , vol.9 , pp. R137
    • Zhang, Y.1
  • 56
    • 70349871718 scopus 로고    scopus 로고
    • CEAS: Cis-regulatory element annotation system
    • Shin, H., Liu, T., Manrai, A. K., Liu, X. S. CEAS: cis-regulatory element annotation system. Bioinformatics 25, 2605-2606, (2009).
    • (2009) Bioinformatics , vol.25 , pp. 2605-2606
    • Shin, H.1    Liu, T.2    Manrai, A.K.3    Liu, X.S.4
  • 57
    • 78651271733 scopus 로고    scopus 로고
    • Integrative genomics viewer
    • Robinson, J. T. et al. Integrative genomics viewer. Nat Biotechnol 29, 24-26 (2011).
    • (2011) Nat Biotechnol , vol.29 , pp. 24-26
    • Robinson, J.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.